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Select item 109494821.

Intestinal lysozyme1 deficiency alters microbiota composition and impacts host metabolism through the emergence of NAD⁺-secreting ASTB Qing110 bacteria

Chengye Zhang, Chen Xiang, Kaichen Zhou, Xingchen Liu, Guofeng Qiao, Yabo Zhao, Kemeng Dong, Ke Sun, Zhihua Liu

mSystems. 2024 Mar; 9(3): e01214-23. Published online 2024 Feb 16. doi: 10.1128/msystems.01214-23

PMCID:: PMC10949482

Abstract Article PDF–1.9M

Select item 107877912.

Loss of Mptx2 alters bacteria composition and intestinal homeostasis potentially by impairing autophagy

Weihui Yan, Shanshan Chen, Ying Wang, Yaying You, Ying Lu, Weipeng Wang, Bo Wu, Jun Du, Shicheng Peng, Wei Cai, Yongtao Xiao

Commun Biol. 2024; 7: 94. Published online 2024 Jan 13. doi: 10.1038/s42003-024-05785-7

PMCID:: PMC10787791

Abstract Article PDF–21M

Select item 104804263.

A tissue-intrinsic IL-33/EGF circuit promotes epithelial regeneration after intestinal injury

Marco Calafiore, Ya-Yuan Fu, Paola Vinci, Viktor Arnhold, Winston Y. Chang, Suze A. Jansen, Anastasiya Egorova, Shuichiro Takashima, Jason Kuttiyara, Takahiro Ito, Jonathan Serody, Susumu Nakae, Heth Turnquist, Johan van Es, Hans Clevers, Caroline A. Lindemans, Bruce R. Blazar, Alan M. Hanash

Nat Commun. 2023; 14: 5411. Published online 2023 Sep 5. doi: 10.1038/s41467-023-40993-5

PMCID:: PMC10480426

Abstract Article PDF–3.2M

Select item 102530024.

TCF7L1 Controls the Differentiation of Tuft Cells in Mouse Small Intestine

Valeriya V. Zinina, Melanie Sauer, Lira Nigmatullina, Nastasja Kreim, Natalia Soshnikova

Cells. 2023 Jun; 12(11): 1452. Published online 2023 May 23. doi: 10.3390/cells12111452

PMCID:: PMC10253002

Abstract Article PDF–2.4M

Select item 98294695.

Maternal exercise improves epithelial development of fetal intestine by enhancing apelin signaling and oxidative metabolism

Song Ah Chae, Jun Seok Son, Jeanene Marie de Avila, Min Du, Mei-Jun Zhu

Am J Physiol Regul Integr Comp Physiol. 2022 Nov 1; 323(5): R728–R738. Published online 2022 Oct 3. doi: 10.1152/ajpregu.00128.2022

PMCID:: PMC9829469

Abstract Article

Select item 97541006.

Pharmacological conversion of gut epithelial cells into insulin-producing cells lowers glycemia in diabetic animals

Wen Du, Junqiang Wang, Taiyi Kuo, Liheng Wang, Wendy M. McKimpson, Jinsook Son, Hitoshi Watanabe, Takumi Kitamoto, Yunkyoung Lee, Remi J. Creusot, Lloyd E. Ratner, Kasi McCune, Ya-Wen Chen, Brendan H. Grubbs, Matthew E. Thornton, Jason Fan, Nishat Sultana, Bryan S. Diaz, Iyshwarya Balasubramanian, Nan Gao, Sandro Belvedere, Domenico Accili

J Clin Invest. 2022 Dec 15; 132(24): e162720. Published online 2022 Dec 15. doi: 10.1172/JCI162720

PMCID:: PMC9754100

Abstract Article PDF–13M

Select item 88217167.

Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling

Martti Maimets, Marianne Terndrup Pedersen, Jordi Guiu, Jes Dreier, Malte Thodberg, Yasuko Antoku, Pawel J. Schweiger, Leonor Rib, Raul Bardini Bressan, Yi Miao, K. Christopher Garcia, Albin Sandelin, Palle Serup, Kim B. Jensen

Nat Commun. 2022; 13: 715. Published online 2022 Feb 7. doi: 10.1038/s41467-022-28369-7

PMCID:: PMC8821716

Abstract Article PDF–8.3M

Select item 79387708.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 76631239.

Targeted Disruption of Mouse Dip2B Leads to Abnormal Lung Development and Prenatal Lethality

Rajiv Kumar Sah, Jun Ma, Fatoumata Binta Bah, Zhenkai Xing, Salah Adlat, Zin Ma Oo, Yajun Wang, Noor Bahadar, Ameer Ali Bohio, Farooq Hayel Nagi, Xuechao Feng, Luqing Zhang, Yaowu Zheng

Int J Mol Sci. 2020 Nov; 21(21): 8223. Published online 2020 Nov 3. doi: 10.3390/ijms21218223

PMCID:: PMC7663123

Abstract Article PDF–4.7M

Select item 746161510.

Paneth cell-derived lysozyme defines the composition of mucolytic microbiota and the inflammatory tone of the intestine

Shiyan Yu, Iyshwarya Balasubramanian, Daniel Laubitz, Kevin Tong, Sheila Bandyopadhyay, Xiang Lin, Juan Flores, Rajbir Singh, Yue Liu, Carlos Macazana, Yanlin Zhao, Fabienne Béguet-Crespel, Karuna Patil, Monica T Midura-Kiela, Daniel Wang, George S. Yap, Ronaldo P. Ferraris, Zhi Wei, Edward M. Bonder, Max M. Häggblom, Lanjing Zhang, Veronique Douard, Michael P. Verzi, Ken Cadwell, Pawel R. Kiela, Nan Gao

Immunity. Author manuscript; available in PMC 2021 Aug 18.

Published in final edited form as: Immunity. 2020 Aug 18; 53(2): 398–416.e8. doi: 10.1016/j.immuni.2020.07.010

PMCID:: PMC7461615

Abstract Article PDF–4.2M

Select item 738563911.

LIF is essential for ISC function and protects against radiation-induced gastrointestinal syndrome

Huaying Wang, Jianming Wang, Yuhan Zhao, Xiao Zhang, Juan Liu, Cen Zhang, Bruce Haffty, Michael Verzi, Lanjing Zhang, Nan Gao, Zhaohui Feng, Wenwei Hu

Cell Death Dis. 2020 Jul; 11(7): 588. Published online 2020 Jul 27. doi: 10.1038/s41419-020-02790-6

PMCID:: PMC7385639

Abstract Article PDF–8.8M

Select item 733298112.

LGR5 controls extracellular matrix production by stem cells in the developing intestine

Valeria Fernandez Vallone, Morgane Leprovots, Didac Ribatallada‐Soriano, Romain Gerbier, Anne Lefort, Frédérick Libert, Gilbert Vassart, Marie‐Isabelle Garcia

EMBO Rep. 2020 Jul 3; 21(7): e49224. Published online 2020 May 28. doi: 10.15252/embr.201949224

PMCID:: PMC7332981

Abstract Article PDF–7.1M

Select item 698692813.

Tracing the origin of adult intestinal stem cells

Jordi Guiu, Edouard Hannezo, Shiro Yui, Samuel Demharter, Svetlana Ulyanchenko, Martti Maimets, Anne Jørgensen, Signe Perlman, Lene Lundvall, Linn Salto Mamsen, Agnete Larsen, Rasmus H. Olesen, Claus Yding Andersen, Lea Langhoff Thuesen, Kristine Juul Hare, Tune H. Pers, Konstantin Khodosevich, Benjamin D. Simons, Kim B. Jensen

Nature. Author manuscript; available in PMC 2020 Jan 28.

Published in final edited form as: Nature. 2019 Jun 1; 570(7759): 107–111. Published online 2019 May 15. doi: 10.1038/s41586-019-1212-5

PMCID:: PMC6986928

Abstract Article PDF–7.0M

Select item 696905214.

Single cell and genetic analyses reveal conserved populations and signaling mechanisms of gastrointestinal stromal niches

Ji-Eun Kim, Lijiang Fei, Wen-Chi Yin, Sabrina Coquenlorge, Abilasha Rao-Bhatia, Xiaoyun Zhang, Sammy Shun Wai Shi, Ju Hee Lee, Noah A. Hahn, Wasi Rizvi, Kyoung-Han Kim, Hoon-Ki Sung, Chi-chung Hui, Guoji Guo, Tae-Hee Kim

Nat Commun. 2020; 11: 334. Published online 2020 Jan 17. doi: 10.1038/s41467-019-14058-5

PMCID:: PMC6969052

Abstract Article PDF–8.7M

Select item 693639815.

Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion

Johan H. van Es, Kay Wiebrands, Carmen López-Iglesias, Marc van de Wetering, Laura Zeinstra, Maaike van den Born, Jeroen Korving, Nobuo Sasaki, Peter J. Peters, Alexander van Oudenaarden, Hans Clevers

Proc Natl Acad Sci U S A. 2019 Dec 26; 116(52): 26599–26605. Published online 2019 Dec 16. doi: 10.1073/pnas.1801888117

PMCID:: PMC6936398

Abstract Article PDF–2.3M

Select item 685102416.

Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Is Highly Expressed in Mouse Tissues With Metabolic Function

Tatiana Danilova, Emilia Galli, Emmi Pakarinen, Erik Palm, Päivi Lindholm, Mart Saarma, Maria Lindahl

Front Endocrinol (Lausanne) 2019; 10: 765. Published online 2019 Nov 6. doi: 10.3389/fendo.2019.00765

PMCID:: PMC6851024

Abstract Article PDF–3.8M

Select item 679689717.

Intestinal lysozyme liberates Nod1 ligands from microbes to direct insulin trafficking in pancreatic beta cells

Qin Zhang, Ying Pan, Benhua Zeng, Xiaojiao Zheng, Haifang Wang, Xueying Shen, Hui Li, Qian Jiang, Jiaxu Zhao, Zhuo-Xian Meng, Pingping Li, Zhengjun Chen, Hong Wei, Zhihua Liu

Cell Res. 2019 Jul; 29(7): 516–532. Published online 2019 Jun 14. doi: 10.1038/s41422-019-0190-3

PMCID:: PMC6796897

Abstract Article PDF–6.7M

Select item 629804018.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 603508519.

Paneth cell multi-potency induced by Notch activation following injury

Shiyan Yu, Kevin Tong, Yanlin Zhao, Iyshwarya Balasubramanian, George S. Yap, Ronaldo P. Ferraris, Edward M. Bonder, Michael P. Verzi, Nan Gao

Cell Stem Cell. Author manuscript; available in PMC 2019 Jul 5.

Published in final edited form as: Cell Stem Cell. 2018 Jul 5; 23(1): 46–59.e5. Published online 2018 Jun 7. doi: 10.1016/j.stem.2018.05.002

PMCID:: PMC6035085

Abstract Article PDF–1.7M

Select item 590259020.

Id2 Determines Intestinal Identity through Repression of the Foregut Transcription Factor Irx5

Kentaro Mori, Harumi Nakamura, Hisanori Kurooka, Hitoshi Miyachi, Kota Tamada, Manabu Sugai, Toru Takumi, Yoshifumi Yokota

Mol Cell Biol. 2018 May 1; 38(9): e00250-17. Prepublished online 2018 Feb 20. Published online 2018 Apr 16. doi: 10.1128/MCB.00250-17

PMCID:: PMC5902590

Abstract Article PDF–4.4M

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