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Select item 111935221.

Extracellular glucose and dysfunctional insulin receptor signaling independently upregulate arterial smooth muscle TMEM16A expression

Somasundaram Raghavan, Masuma Akter Brishti, Angelica Bernardelli, Alejandro Mata-Daboin, Jonathan H. Jaggar, M. Dennis Leo

Am J Physiol Cell Physiol. 2024 Apr 1; 326(4): C1237–C1247. Published online 2024 Mar 4. doi: 10.1152/ajpcell.00555.2023

PMCID:: PMC11193522

Abstract Article

Select item 110722912.

Tubular TMEM16A promotes tubulointerstitial fibrosis by suppressing PGC-1α-mediated mitochondrial homeostasis in diabetic kidney disease

Jia-Ling Ji, Jun-Ying Li, Jian-Xiang Liang, Yan Zhou, Cong-Cong Liu, Yao Zhang, Ai-Qing Zhang, Hong Liu, Rui-Xia Ma, Zuo-Lin Li

Cell Mol Life Sci. 2023 Dec; 80(12): 347. Published online 2023 Nov 6. doi: 10.1007/s00018-023-05000-6

PMCID:: PMC11072291

Abstract Article PDF–14M

Select item 108897213.

A Pharmacological Investigation of the TMEM16A Currents in Murine Skeletal Myogenic Precursor Cells

Marina Sciancalepore, Asja Ragnini, Paola Zacchi, Violetta Borelli, Paola D’Andrea, Paola Lorenzon, Annalisa Bernareggi

Int J Mol Sci. 2024 Feb; 25(4): 2225. Published online 2024 Feb 13. doi: 10.3390/ijms25042225

PMCID:: PMC10889721

Abstract Article PDF–4.6M

Select item 108442224.

TMEM16A in smooth muscle cells acts as a pacemaker channel in the internal anal sphincter

Ping Lu, Lawrence M. Lifshitz, Karl Bellve, Ronghua ZhuGe

Commun Biol. 2024; 7: 151. Published online 2024 Feb 5. doi: 10.1038/s42003-024-05850-1

PMCID:: PMC10844222

Abstract Article PDF–3.5M

Select item 105850955.

IP3R1 underlies diastolic ANO1 activation and pressure-dependent chronotropy in lymphatic collecting vessels

Scott D. Zawieja, Grace A. Pea, Sarah E. Broyhill, Advaya Patro, Karen H. Bromert, Min Li, Charles E. Norton, Jorge A. Castorena-Gonzalez, Edward J. Hancock, Christopher D. Bertram, Michael J. Davis

J Gen Physiol. 2023 Dec 4; 155(12): e202313358. Published online 2023 Oct 18. doi: 10.1085/jgp.202313358

PMCID:: PMC10585095

Abstract Article PDF–6.3M

Select item 103593776.

KCNE1 does not shift TMEM16A from a Ca²⁺ dependent to a voltage dependent Cl^- channel and is not expressed in renal proximal tubule

Khaoula Talbi, Jiraporn Ousingsawat, Raquel Centeio, Rainer Schreiber, Karl Kunzelmann

Pflugers Arch. 2023; 475(8): 995–1007. Published online 2023 Jul 13. doi: 10.1007/s00424-023-02829-5

PMCID:: PMC10359377

Abstract Article PDF–3.8M

Select item 102064267.

TMEM16A/F support exocytosis but do not inhibit Notch-mediated goblet cell metaplasia of BCi-NS1.1 human airway epithelium

Raquel Centeio, Inês Cabrita, Rainer Schreiber, Karl Kunzelmann

Front Physiol. 2023; 14: 1157704. Published online 2023 May 9. doi: 10.3389/fphys.2023.1157704

PMCID:: PMC10206426

Abstract Article PDF–3.0M

Select item 97925908.

Hepatocyte-specific TMEM16A deficiency alleviates hepatic ischemia/reperfusion injury via suppressing GPX4-mediated ferroptosis

Jiawei Guo, Zihao Song, Jie Yu, Chengyi Li, Chenchen Jin, Wei Duan, Xiu Liu, Yingying Liu, Shuai Huang, Yonghua Tuo, Fei Pei, Zhengyang Jian, Pengyu Zhou, Shaoyi Zheng, Zhaowei Zou, Feng Zhang, Quan Gong, Sijia Liang

Cell Death Dis. 2022 Dec; 13(12): 1072. Published online 2022 Dec 26. doi: 10.1038/s41419-022-05518-w

PMCID:: PMC9792590

Abstract Article PDF–5.8M

Select item 97304529.

Developmental spontaneous activity promotes formation of sensory domains, frequency tuning and proper gain in central auditory circuits

Calvin J. Kersbergen, Travis A. Babola, Jason Rock, Dwight E. Bergles

Cell Rep. Author manuscript; available in PMC 2022 Dec 8.

Published in final edited form as: Cell Rep. 2022 Nov 15; 41(7): 111649. doi: 10.1016/j.celrep.2022.111649

PMCID:: PMC9730452

Abstract Article PDF–4.6M

Select item 964751810.

Intracellular TMEM16A is necessary for myogenesis of skeletal muscle

Wen Yuan, Cong-Cong Cui, Jing Li, Yan-Hua Xu, Chun-E Fan, Yu-Chen Chen, Hong-Wei Fan, Bing-Xue Hu, Mei-Yun Shi, Zhi-Yuan Sun, Pei Wang, Teng-Xiang Ma, Zhao Zhang, Min-Sheng Zhu, Hua-Qun Chen

iScience. 2022 Nov 18; 25(11): 105446. Published online 2022 Nov 8. doi: 10.1016/j.isci.2022.105446

PMCID:: PMC9647518

Abstract Article PDF–3.2M

Select item 919485911.

Gating and anion selectivity are reciprocally regulated in TMEM16A (ANO1)

José J. De Jesús-Pérez, Ana E. López-Romero, Odalys Posadas, Guadalupe Segura-Covarrubias, Iván Aréchiga-Figueroa, Braulio Gutiérrez-Medina, Patricia Pérez-Cornejo, Jorge Arreola

J Gen Physiol. 2022 Aug 1; 154(8): e202113027. Published online 2022 Jun 10. doi: 10.1085/jgp.202113027

PMCID:: PMC9194859

Abstract Article PDF–4.7M

Select item 913032812.

Anoctamin 1 controls bone resorption by coupling Cl⁻ channel activation with RANKL-RANK signaling transduction

Weijia Sun, Shuai Guo, Yuheng Li, JianWei Li, Caizhi Liu, Yafei Chen, Xuzhao Wang, Yingjun Tan, Hua Tian, Cheng Wang, Ruikai Du, Guohui Zhong, Sai Shi, Biao Ma, Chang Qu, Jingxuan Fu, Xiaoyan Jin, Dingsheng Zhao, Yong Zhan, Shukuan Ling, Hailong An, Yingxian Li

Nat Commun. 2022; 13: 2899. Published online 2022 May 24. doi: 10.1038/s41467-022-30625-9