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Items: 1 to 20 of 91

1.
A STUB1 ubiquitin ligase/CHIC2 protein complex negatively regulates the IL-3, IL-5, and GM-CSF cytokine receptor common β chain (CSF2RB) protein stability
Sebastian H.J. Koochaki, Mikołaj Słabicki, Ryan Lumpkin, Charles Zou, Roger Belizaire, Eric S. Fischer, Benjamin L. Ebert
J Biol Chem. 2022 Oct; 298(10): 102484. Published online 2022 Sep 13. doi: 10.1016/j.jbc.2022.102484
PMCID:
PMC9574515
AbstractArticlePDF–1.8M
2.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
3.
STUB1 regulates antiviral RNAi through inducing ubiquitination and degradation of Dicer and AGO2 in mammals
Shumin Zhang, Xuhua Zhang, Yuanyuan Bie, Jing Kong, An Wang, Yang Qiu, Xi Zhou
Virol Sin. 2022 Aug; 37(4): 569–580. Published online 2022 May 6. doi: 10.1016/j.virs.2022.05.001
PMCID:
PMC9437610
AbstractArticlePDF–3.0M
4.
The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery
Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane
Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054
PMCID:
PMC9015699
AbstractArticlePDF–3.3M
5.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
6.
CHIP ameliorates cerebral ischemia-reperfusion injury by attenuating necroptosis and inflammation
Dabao Yao, Shuo Zhang, Zhengwei Hu, Haiyang Luo, Chengyuan Mao, Yu Fan, Mibo Tang, Fen Liu, Si Shen, Liyuan Fan, Mengjie Li, Jingjing Shi, Jiadi Li, Dongrui Ma, Yuming Xu, Changhe Shi
Aging (Albany NY) 2021 Dec 15; 13(23): 25564–25577. Published online 2021 Dec 14. doi: 10.18632/aging.203774
PMCID:
PMC8714161
AbstractArticlePDF–1.5M
7.
TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation
Xiaochen Fan, V Pragathi Masamsetti, Jane QJ Sun, Kasper Engholm-Keller, Pierre Osteil, Joshua Studdert, Mark E Graham, Nicolas Fossat, Patrick PL Tam
eLife. 2021; 10: e62873. Published online 2021 Feb 8. doi: 10.7554/eLife.62873
PMCID:
PMC7968925
AbstractArticlePDF–4.0M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
CHIP protects against MPP+/MPTP-induced damage by regulating Drp1 in two models of Parkinson’s disease
Zhengwei Hu, Chengyuan Mao, Hui Wang, Zhongxian Zhang, Shuo Zhang, Haiyang Luo, Mibo Tang, Jing Yang, Yanpeng Yuan, Yanlin Wang, Yutao Liu, Liyuan Fan, Qimeng Zhang, Dabao Yao, Fen Liu, Jonathan C. Schisler, Changhe Shi, Yuming Xu
Aging (Albany NY) 2021 Jan 15; 13(1): 1458–1472. Published online 2021 Jan 2. doi: 10.18632/aging.202389
PMCID:
PMC7834979
AbstractArticlePDF–3.3M
10.
UBXN2A regulates nicotinic receptor degradation by modulating the E3 ligase activity of CHIP
Yanfen Teng, Khosrow Rezvani, Mariella De Biasi
Biochem Pharmacol. Author manuscript; available in PMC 2021 Jan 4.
Published in final edited form as: Biochem Pharmacol. 2015 Oct 15; 97(4): 518–530. Published online 2015 Aug 8. doi: 10.1016/j.bcp.2015.08.084
PMCID:
PMC7780642
AbstractArticlePDF–1.5M
11.
CHIP phosphorylation by protein kinase G enhances protein quality control and attenuates cardiac ischemic injury
Mark J. Ranek, Christian Oeing, Rebekah Sanchez-Hodge, Kristen M. Kokkonen-Simon, Danielle Dillard, M. Imran Aslam, Peter P. Rainer, Sumita Mishra, Brittany Dunkerly-Eyring, Ronald J. Holewinski, Cornelia Virus, Huaqun Zhang, Matthew M. Mannion, Vineet Agrawal, Virginia Hahn, Dong I. Lee, Masayuki Sasaki, Jennifer E. Van Eyk, Monte S. Willis, Richard C. Page, Jonathan C. Schisler, David A. Kass
Nat Commun. 2020; 11: 5237. Published online 2020 Oct 20. doi: 10.1038/s41467-020-18980-x
PMCID:
PMC7575552
AbstractArticlePDF–2.3M
12.
Deletion of the Ubiquitin Ligase CHIP Leads to the Accumulation, But Not the Aggregation, of Both Endogenous Phospho- and Caspase-3-Cleaved Tau Species
Chad A. Dickey, Mei Yue, Wen-Lang Lin, Dennis W. Dickson, Judith H. Dunmore, Wing C. Lee, Cynthia Zehr, Gemma West, Songsong Cao, Amber M. K. Clark, Guy A. Caldwell, Kim A. Caldwell, Christopher Eckman, Cam Patterson, Michael Hutton, Leonard Petrucelli
J Neurosci. 2006 Jun 28; 26(26): 6985–6996. doi: 10.1523/JNEUROSCI.0746-06.2006
PMCID:
PMC6673930
AbstractArticlePDF–687K
13.
CHIP Overexpression Reduces Mutant Androgen Receptor Protein and Ameliorates Phenotypes of the Spinal and Bulbar Muscular Atrophy Transgenic Mouse Model
Hiroaki Adachi, Masahiro Waza, Keisuke Tokui, Masahisa Katsuno, Makoto Minamiyama, Fumiaki Tanaka, Manabu Doyu, Gen Sobue
J Neurosci. 2007 May 9; 27(19): 5115–5126. doi: 10.1523/JNEUROSCI.1242-07.2007
PMCID:
PMC6672370
AbstractArticlePDF–1.4M
14.
New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules
Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer
J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252
PMCID:
PMC6602300
AbstractArticle
15.
Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system
Laura Rinaldi, Rossella Delle Donne, Bruno Catalanotti, Omar Torres-Quesada, Florian Enzler, Federica Moraca, Robert Nisticò, Francesco Chiuso, Sonia Piccinin, Verena Bachmann, Herbert H Lindner, Corrado Garbi, Antonella Scorziello, Nicola Antonino Russo, Matthis Synofzik, Ulrich Stelzl, Lucio Annunziato, Eduard Stefan, Antonio Feliciello
Nat Commun. 2019; 10: 2572. Published online 2019 Jun 12. doi: 10.1038/s41467-019-10037-y
Correction in:
Nat Commun. 2024; 15: 4565.
PMCID:
PMC6561907
AbstractArticlePDF–2.5M
16.
The host cell ubiquitin ligase protein CHIP is a potent suppressor of HIV-1 replication
Amjad Ali, Sabihur Rahman Farooqui, Akhil C. Banerjea
J Biol Chem. 2019 May 3; 294(18): 7283–7295. Published online 2019 Mar 18. doi: 10.1074/jbc.RA118.007257
PMCID:
PMC6509501
AbstractArticlePDF–2.2M
17.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
18.
UBXN2A enhances CHIP‐mediated proteasomal degradation of oncoprotein mortalin‐2 in cancer cells
Sanam Sane, Andre Hafner, Rekha Srinivasan, Daniall Masood, John l. Slunecka, Collin J. Noldner, Alex D. Hanson, Taylor Kruisselbrink, Xuejun Wang, Yiyang Wang, Jun Yin, Khosrow Rezvani
Mol Oncol. 2018 Oct; 12(10): 1753–1777. Published online 2018 Sep 3. doi: 10.1002/1878-0261.12372
PMCID:
PMC6166003
AbstractArticlePDF–1.7M
19.
Adverse Effects of Fenofibrate in Mice Deficient in the Protein Quality Control Regulator, CHIP
Saranya Ravi, Traci L. Parry, Monte S. Willis, Pamela Lockyer, Cam Patterson, James R. Bain, Robert D. Stevens, Olga R. Ilkayeva, Christopher B. Newgard, Jonathan C. Schisler
J Cardiovasc Dev Dis. 2018 Sep; 5(3): 43. Published online 2018 Aug 15. doi: 10.3390/jcdd5030043
PMCID:
PMC6162787
AbstractArticlePDF–4.3M
20.
Disrupted structure and aberrant function of CHIP mediates the loss of motor and cognitive function in preclinical models of SCAR16
Chang-he Shi, Carrie Rubel, Sarah E. Soss, Rebekah Sanchez-Hodge, Shuo Zhang, Sabrina C. Madrigal, Saranya Ravi, Holly McDonough, Richard C. Page, Walter J. Chazin, Cam Patterson, Cheng-yuan Mao, Monte S. Willis, Hai-Yang Luo, Yu-sheng Li, Donte A. Stevens, Mi-bo Tang, Pan Du, Yao-he Wang, Zheng-wei Hu, Yu-ming Xu, Jonathan C. Schisler
PLoS Genet. 2018 Sep; 14(9): e1007664. Published online 2018 Sep 17. doi: 10.1371/journal.pgen.1007664
PMCID:
PMC6160236
AbstractArticlePDF–17M

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