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Select item 111419141.

Role of the mitochondrial protein cyclophilin D in skin wound healing and collagen secretion

Ritu Bansal, Monica Torres, Matthew Hunt, Nuoqi Wang, Margarita Chatzopoulou, Mansi Manchanda, Evan P. Taddeo, Cynthia Shu, Orian S. Shirihai, Etty Bachar-Wikstrom, Jakob D. Wikstrom

JCI Insight. 2024 May 8; 9(9): e169213. Published online 2024 Apr 2. doi: 10.1172/jci.insight.169213

PMCID:: PMC11141914

Abstract Article PDF–28M

Select item 109942892.

Cyclophilin D knockout significantly prevents HCC development in a streptozotocin-induced mouse model of diabetes-linked NASH

Winston T. Stauffer, Michael Bobardt, Daren R. Ure, Robert T. Foster, Philippe Gallay

PLoS One. 2024; 19(4): e0301711. Published online 2024 Apr 4. doi: 10.1371/journal.pone.0301711

PMCID:: PMC10994289

Abstract Article PDF–3.0M

Select item 108979193.

Coordinated metabolic responses to cyclophilin D deletion in the developing heart

Gisela Beutner, Jonathan Ryan Burris, Michael P. Collins, Chaitanya A. Kulkarni, Sergiy M. Nadtochiy, Karen L. de Mesy Bentley, Ethan D. Cohen, Paul S. Brookes, George A. Porter, Jr.

iScience. 2024 Mar 15; 27(3): 109157. Published online 2024 Feb 9. doi: 10.1016/j.isci.2024.109157

PMCID:: PMC10897919

Abstract Article PDF–5.5M

Select item 108020724.

Inhibition of mitochondrial cyclophilin D, a downstream target of glycogen synthase kinase 3α, improves sperm motility

Seung Hyun Park, Myung Chan Gye

Reprod Biol Endocrinol. 2024; 22: 15. Published online 2024 Jan 22. doi: 10.1186/s12958-024-01186-x

PMCID:: PMC10802072

Abstract Article PDF–4.4M

Select item 105142195.

CypD induced ROS output promotes intracranial aneurysm formation and rupture by 8-OHdG/NLRP3/MMP9 pathway

Haiyan Fan, Hao Tian, Fa Jin, Xin Zhang, Shixing Su, Yanchao Liu, Zhuohua Wen, Xuying He, Xifeng Li, Chuanzhi Duan

Redox Biol. 2023 Nov; 67: 102887. Published online 2023 Sep 12. doi: 10.1016/j.redox.2023.102887

PMCID:: PMC10514219

Abstract Article PDF–13M

Select item 104568526.

ANT-dependent MPTP underlies necrotic myofiber death in muscular dystrophy

Michael J. Bround, Julian R. Havens, Allen J. York, Michelle A. Sargent, Jason Karch, Jeffery D. Molkentin

Sci Adv. 2023 Aug; 9(34): eadi2767. Published online 2023 Aug 25. doi: 10.1126/sciadv.adi2767

PMCID:: PMC10456852

Abstract Article PDF–1.2M

Select item 102061907.

Mitochondrial membrane potential instability on reperfusion after ischemia does not depend on mitochondrial Ca²⁺ uptake

Deepthi Ashok, Kyriakos Papanicolaou, Agnieszka Sidor, Michelle Wang, Soroosh Solhjoo, Ting Liu, Brian O’Rourke

J Biol Chem. 2023 Jun; 299(6): 104708. Published online 2023 Apr 14. doi: 10.1016/j.jbc.2023.104708

PMCID:: PMC10206190

Abstract Article PDF–4.8M

Select item 100532658.

MicroRNA‐155‐5p in serum derived‐exosomes promotes ischaemia–reperfusion injury by reducing CypD ubiquitination by NEDD4

Chenkai Hu, Junyu Liao, Ruiyan Huang, Qiang Su, Lei He

ESC Heart Fail. 2023 Apr; 10(2): 1144–1157. Published online 2023 Jan 11. doi: 10.1002/ehf2.14279

PMCID:: PMC10053265

Abstract Article PDF–2.3M

Select item 98565159.

Genetic Inhibition of Mitochondrial Permeability Transition Pore Exacerbates Ryanodine Receptor 2 Dysfunction in Arrhythmic Disease

Arpita Deb, Brian D. Tow, You Qing, Madelyn Walker, Emmanuel R. Hodges, James A. Stewart, Jr., Björn C. Knollmann, Yi Zheng, Ying Wang, Bin Liu

Cells. 2023 Jan; 12(2): 204. Published online 2023 Jan 4. doi: 10.3390/cells12020204

PMCID:: PMC9856515

Abstract Article PDF–3.8M

Select item 972477210.

SR-Mitochondria Crosstalk Shapes Ca Signalling to Impact Pathophenotype in Disease Models Marked by Dysregulated Intracellular Ca Release

Brian D Tow, Arpita Deb, Shraddha Neupane, Shuchi M Patel, Meagan Reed, Anna-Beth Loper, Roman A Eliseev, Björn C Knollmann, Sándor Györke, Bin Liu

Cardiovasc Res. 2022 Sep; 118(13): 2819–2832. Published online 2021 Oct 22. doi: 10.1093/cvr/cvab324

PMCID:: PMC9724772

Abstract Article PDF–1.3M

Select item 956946511.

Remodeling of Liver and Plasma Lipidomes in Mice Lacking Cyclophilin D

Balazs Koszegi, Gabor Balogh, Zoltan Berente, Anett Vranesics, Edit Pollak, Laszlo Molnar, Aniko Takatsy, Viktoria Poor, Matyas Wahr, Csenge Antus, Krisztian Eros, Laszlo Vigh, Ferenc Gallyas, Jr., Maria Peter, Balazs Veres

Int J Mol Sci. 2022 Oct; 23(19): 11274. Published online 2022 Sep 24. doi: 10.3390/ijms231911274

PMCID:: PMC9569465

Abstract Article PDF–2.1M

Select item 945836812.

SIRT3-Mediated CypD-K166 Deacetylation Alleviates Neuropathic Pain by Improving Mitochondrial Dysfunction and Inhibiting Oxidative Stress

Binbin Yan, Qiang Liu, Xiaobao Ding, Yuwen Lin, Xiaowei Jiao, Yuqing Wu, Huihui Miao, Chenghua Zhou

Oxid Med Cell Longev. 2022; 2022: 4722647. Published online 2022 Sep 1. doi: 10.1155/2022/4722647

PMCID:: PMC9458368

Abstract Article PDF–3.0M

Select item 928254613.

The effect of Cyclophilin D depletion on liver regeneration following associating liver partition and portal vein ligation for staged hepatectomy

Noemi Daradics, Gergo Horvath, Laszlo Tretter, Agnes Paal, Andras Fulop, Andras Budai, Attila Szijarto

PLoS One. 2022; 17(7): e0271606. Published online 2022 Jul 14. doi: 10.1371/journal.pone.0271606

PMCID:: PMC9282546

Abstract Article PDF–2.2M

Select item 919189114.

Transcriptional regulation of cyclophilin D by BMP/Smad signaling and its role in osteogenic differentiation

Rubens Sautchuk, Brianna H Kalicharan, Katherine Escalera-Rivera, Jennifer H Jonason, George A Porter, Hani A Awad, Roman A Eliseev

eLife. 2022; 11: e75023. Published online 2022 May 30. doi: 10.7554/eLife.75023

PMCID:: PMC9191891

Abstract Article PDF–7.2M

Select item 910751215.

Enhanced NCLX-dependent mitochondrial Ca²⁺ efflux attenuates pathological remodeling in heart failure

Joanne F. Garbincius, Timothy S. Luongo, Pooja Jadiya, Alycia N. Hildebrand, Devin W. Kolmetzky, Adam S. Mangold, Rajika Roy, Jessica Ibetti, Mary Nwokedi, Walter J. Koch, John W. Elrod

J Mol Cell Cardiol. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: J Mol Cell Cardiol. 2022 Jun; 167: 52–66. Published online 2022 Mar 28. doi: 10.1016/j.yjmcc.2022.03.001

PMCID:: PMC9107512

Abstract Article PDF–2.5M

Select item 893265216.

Uncontrolled mitochondrial calcium uptake underlies the pathogenesis of neurodegeneration in MICU1-deficient mice and patients

Raghavendra Singh, Adam Bartok, Melanie Paillard, Ashley Tyburski, Melanie Elliott, György Hajnóczky

Sci Adv. 2022 Mar; 8(11): eabj4716. Published online 2022 Mar 18. doi: 10.1126/sciadv.abj4716

PMCID:: PMC8932652

Abstract Article PDF–5.1M

Select item 875235517.

Genetic deletion of p66shc and/or cyclophilin D results in decreased pulmonary vascular tone

Mareike Gierhardt, Oleg Pak, Akylbek Sydykov, Simone Kraut, Julia Schäffer, Claudia Garcia, Christine Veith, Esraa M Zeidan, Monika Brosien, Karin Quanz, Azadeh Esfandiary, Alireza Saraji, Stefan Hadzic, Baktybek Kojonazarov, Jochen Wilhelm, Hossein A Ghofrani, Ralph T Schermuly, Werner Seeger, Friedrich Grimminger, Christiane Herden, Rainer Schulz, Norbert Weissmann, Jacqueline Heger, Natascha Sommer

Cardiovasc Res. 2022 Jan; 118(1): 305–315. Published online 2020 Oct 29. doi: 10.1093/cvr/cvaa310

PMCID:: PMC8752355

Abstract Article PDF–941K

Select item 854056218.

Cyclophilin D Regulates the Nuclear Translocation of AIF, Cardiac Endothelial Cell Necroptosis and Murine Cardiac Transplant Injury

Adnan Qamar, Jianqi Zhao, Laura Xu, Patrick McLeod, Xuyan Huang, Jifu Jiang, Weihua Liu, Aaron Haig, Zhu-Xu Zhang

Int J Mol Sci. 2021 Oct; 22(20): 11038. Published online 2021 Oct 13. doi: 10.3390/ijms222011038

PMCID:: PMC8540562

Abstract Article PDF–37M

Select item 813132419.

The effect of mitochondrial calcium uniporter and cyclophilin D knockout on resistance of brain mitochondria to Ca²⁺-induced damage

James Hamilton, Tatiana Brustovetsky, Nickolay Brustovetsky

J Biol Chem. 2021 Jan-Jun; 296: 100669. Published online 2021 Apr 16. doi: 10.1016/j.jbc.2021.100669

PMCID:: PMC8131324

Abstract Article PDF–2.7M

Select item 793877020.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

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