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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 94778532.

Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro

Tulsi Patel, Jennifer Hammelman, Siaresh Aziz, Sumin Jang, Michael Closser, Theodore L. Michaels, Jacob A. Blum, David K. Gifford, Hynek Wichterle

Nat Commun. 2022; 13: 5427. Published online 2022 Sep 15. doi: 10.1038/s41467-022-33022-4

PMCID:: PMC9477853

Abstract Article PDF–7.4M

Select item 79387703.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78563464.

Tropomodulin1 Expression Increases Upon Maturation in Dendritic Cells and Promotes Their Maturation and Immune Functions

Xianmei Liu, Xue Xia, Xifu Wang, Jing Zhou, Lanping Amy Sung, Jinhua Long, Xueyu Geng, Zhu Zeng, Weijuan Yao

Front Immunol. 2020; 11: 587441. Published online 2021 Jan 15. doi: 10.3389/fimmu.2020.587441

PMCID:: PMC7856346

Abstract Article PDF–2.9M

Select item 72950335.

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant

Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely

Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089

PMCID:: PMC7295033

Abstract Article PDF–2.7M

Select item 67969266.

Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate

Rui Gao, Xingqun Liang, Sirisha Cheedipudi, Julio Cordero, Xue Jiang, Qingquan Zhang, Luca Caputo, Stefan Günther, Carsten Kuenne, Yonggang Ren, Shoumo Bhattacharya, Xuejun Yuan, Guillermo Barreto, Yihan Chen, Thomas Braun, Sylvia M. Evans, Yunfu Sun, Gergana Dobreva

Cell Res. 2019 Jun; 29(6): 486–501. Published online 2019 Apr 25. doi: 10.1038/s41422-019-0168-1

PMCID:: PMC6796926

Abstract Article PDF–6.5M

Select item 65547237.

Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca²⁺/CaM) and CaM Kinase II (CaMKII) Binding Partner

Paul R. Evans, Kyle J. Gerber, Eric B. Dammer, Duc M. Duong, Devrishi Goswami, Daniel J. Lustberg, Juan Zou, Jenny J. Yang, Serena M. Dudek, Patrick R. Griffin, Nicholas T. Seyfried, John R. Hepler

J Proteome Res. Author manuscript; available in PMC 2019 Jun 7.

Published in final edited form as: J Proteome Res. 2018 Apr 6; 17(4): 1700–1711. Published online 2018 Mar 20. doi: 10.1021/acs.jproteome.8b00027

PMCID:: PMC6554723

Abstract Article PDF–2.0M

Select item 64595108.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 57669109.

The actin-organizing formin protein Fhod3 is required for postnatal development and functional maintenance of the adult heart in mice

Tomoki Ushijima, Noriko Fujimoto, Sho Matsuyama, Meikun Kan-o, Hiroshi Kiyonari, Go Shioi, Yohko Kage, Sho Yamasaki, Ryu Takeya, Hideki Sumimoto

J Biol Chem. 2018 Jan 5; 293(1): 148–162. Published online 2017 Nov 20. doi: 10.1074/jbc.M117.813931

PMCID:: PMC5766910

Abstract Article PDF–4.5M

Select item 569259210.

HSPB7 is indispensable for heart development by modulating actin filament assembly

Tongbin Wu, Yongxin Mu, Julius Bogomolovas, Xi Fang, Jennifer Veevers, Roberta B. Nowak, Christopher T. Pappas, Carol C. Gregorio, Sylvia M. Evans, Velia M. Fowler, Ju Chen

Proc Natl Acad Sci U S A. 2017 Nov 7; 114(45): 11956–11961. Published online 2017 Oct 23. doi: 10.1073/pnas.1713763114

PMCID:: PMC5692592

Abstract Article PDF–1.1M

Select item 558027611.

Tropomodulin 1 controls erythroblast enucleation via regulation of F-actin in the enucleosome

Roberta B. Nowak, Julien Papoin, David S. Gokhin, Carla Casu, Stefano Rivella, Jeffrey M. Lipton, Lionel Blanc, Velia M. Fowler

Blood. 2017 Aug 31; 130(9): 1144–1155. Prepublished online 2017 Jul 20. doi: 10.1182/blood-2017-05-787051

PMCID:: PMC5580276

Abstract Article

Select item 550797912.

Circulating primitive erythroblasts establish a functional, protein 4.1R-dependent cytoskeletal network prior to enucleating

Yu-Shan Huang, Luis F. Delgadillo, Kathryn H. Cyr, Paul D. Kingsley, Xiuli An, Kathleen E. McGrath, Narla Mohandas, John G. Conboy, Richard E. Waugh, Jiandi Wan, James Palis

Sci Rep. 2017; 7: 5164. Published online 2017 Jul 12. doi: 10.1038/s41598-017-05498-4

PMCID:: PMC5507979

Abstract Article PDF–2.1M

Select item 498676813.

Tropomodulin 1 Regulation of Actin Is Required for the Formation of Large Paddle Protrusions Between Mature Lens Fiber Cells

Catherine Cheng, Roberta B. Nowak, Sondip K. Biswas, Woo-Kuen Lo, Paul G. FitzGerald, Velia M. Fowler

Invest Ophthalmol Vis Sci. 2016 Aug; 57(10): 4084–4099. Published online 2016 Aug 8. doi: 10.1167/iovs.16-19949

PMCID:: PMC4986768

Abstract Article PDF–3.1M

Select item 468922014.

Tropomodulin 1 directly controls thin filament length in both wild-type and tropomodulin 4-deficient skeletal muscle

David S. Gokhin, Julien Ochala, Andrea A. Domenighetti, Velia M. Fowler

Development. 2015 Dec 15; 142(24): 4351–4362. doi: 10.1242/dev.129171

PMCID:: PMC4689220

Abstract Article

Select item 464078015.

Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality

Christopher T. Pappas, Rachel M. Mayfield, Christine Henderson, Nima Jamilpour, Cathleen Cover, Zachary Hernandez, Kirk R. Hutchinson, Miensheng Chu, Ki-Hwan Nam, Jose M. Valdez, Pak Kin Wong, Henk L. Granzier, Carol C. Gregorio

Proc Natl Acad Sci U S A. 2015 Nov 3; 112(44): 13573–13578. Published online 2015 Oct 20. doi: 10.1073/pnas.1508273112