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Items: 1 to 20 of 24

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
A widely distributed gene cluster compensates for uricase loss in hominids
Yuanyuan Liu, J. Bryce Jarman, Yen S. Low, Hannah E. Augustijn, Steven Huang, Haoqing Chen, Mary E. DeFeo, Kazuma Sekiba, Bi-Huei Hou, Xiandong Meng, Allison M. Weakley, Ashley V. Cabrera, Zhiwei Zhou, Gilles van Wezel, Marnix H. Medema, Calyani Ganesan, Alan C. Pao, Saurabh Gombar, Dylan Dodd
Cell. Author manuscript; available in PMC 2024 Aug 3.
Published in final edited form as: Cell. 2023 Aug 3; 186(16): 3400–3413.e20. doi: 10.1016/j.cell.2023.06.010
Correction in:
Cell. 2023 Sep 28; 186(20): 4472–4473.
PMCID:
PMC10421625
AbstractArticlePDF–1.8M
3.
Vitamin C transporter SVCT1 serves a physiological role as a urate importer: functional analyses and in vivo investigations
Yu Toyoda, Hiroshi Miyata, Naohiro Uchida, Keito Morimoto, Ryuichiro Shigesawa, Hidetoshi Kassai, Kazuki Nakao, Naoko H. Tomioka, Hirotaka Matsuo, Kimiyoshi Ichida, Makoto Hosoyamada, Atsu Aiba, Hiroshi Suzuki, Tappei Takada
Pflugers Arch. 2023; 475(4): 489–504. Published online 2023 Feb 7. doi: 10.1007/s00424-023-02792-1
PMCID:
PMC10011331
AbstractArticlePDF–1.0M
4.
Alteration of Gut Microbiome and Correlated Amino Acid Metabolism Contribute to Hyperuricemia and Th17-Driven Inflammation in Uox-KO Mice
Siyue Song, Yu Lou, Yingying Mao, Xianghui Wen, Moqi Fan, Zhixing He, Yang Shen, Chengping Wen, Tiejuan Shao
Front Immunol. 2022; 13: 804306. Published online 2022 Feb 7. doi: 10.3389/fimmu.2022.804306
PMCID:
PMC8858814
AbstractArticlePDF–11M
5.
Identification of an exporter that regulates vitamin C supply from blood to the brain
Hiroshi Miyata, Yu Toyoda, Tappei Takada, Toshimitsu Hiragi, Yu Kubota, Ryuichiro Shigesawa, Ryuta Koyama, Yuji Ikegaya, Hiroshi Suzuki
iScience. 2022 Jan 21; 25(1): 103642. Published online 2022 Jan 13. doi: 10.1016/j.isci.2021.103642
PMCID:
PMC8786643
AbstractArticlePDF–3.1M
6.
Association of Hyperuricemia With Immune Disorders and Intestinal Barrier Dysfunction
Qiulan Lv, Daxing Xu, Xuezhi Zhang, Xiaomin Yang, Peng Zhao, Xuena Cui, Xiu Liu, Wan Yang, Guanpin Yang, Shichao Xing
Front Physiol. 2020; 11: 524236. Published online 2020 Nov 27. doi: 10.3389/fphys.2020.524236
PMCID:
PMC7729003
AbstractArticlePDF–4.2M
7.
Identification of GLUT12/SLC2A12 as a urate transporter that regulates the blood urate level in hyperuricemia model mice
Yu Toyoda, Tappei Takada, Hiroshi Miyata, Hirotaka Matsuo, Hidetoshi Kassai, Kazuki Nakao, Masahiro Nakatochi, Yusuke Kawamura, Seiko Shimizu, Nariyoshi Shinomiya, Kimiyoshi Ichida, Makoto Hosoyamada, Atsu Aiba, Hiroshi Suzuki
Proc Natl Acad Sci U S A. 2020 Aug 4; 117(31): 18175–18177. Published online 2020 Jul 20. doi: 10.1073/pnas.2006958117
PMCID:
PMC7414087
AbstractArticlePDF–641K
8.
Hyperuricemia Predisposes to the Onset of Diabetes via Promoting Pancreatic β-Cell Death in Uricase-Deficient Male Mice
Jie Lu, Yuwei He, Lingling Cui, Xiaoming Xing, Zhen Liu, Xinde Li, Hui Zhang, Hailong Li, Wenyan Sun, Aichang Ji, Yao Wang, Huiyong Yin, Changgui Li
Diabetes. 2020 Jun; 69(6): 1149–1163. Published online 2020 Apr 20. doi: 10.2337/db19-0704
PMCID:
PMC7243290
AbstractArticlePDF–2.7M
9.
Perfecting a high hypoxanthine phosphoribosyltransferase activity–uricase KO mice to test the effects of purine‐ and non‐purine‐type xanthine dehydrogenase (XDH) inhibitors
Takuji Hosoya, Shunya Uchida, Shigeru Shibata, Naoko H. Tomioka, Makoto Hosoyamada
Br J Pharmacol. 2020 May; 177(10): 2274–2285. Published online 2020 Feb 18. doi: 10.1111/bph.14978
PMCID:
PMC7174878
AbstractArticlePDF–1.3M
10.
Urate‐lowering therapy alleviates atherosclerosis inflammatory response factors and neointimal lesions in a mouse model of induced carotid atherosclerosis
Jie Lu, Mingshu Sun, Xinjiang Wu, Xuan Yuan, Zhen Liu, Xiaojie Qu, Xiaopeng Ji, Tony R. Merriman, Changgui Li
FEBS J. 2019 Apr; 286(7): 1346–1359. Published online 2019 Feb 9. doi: 10.1111/febs.14768
PMCID:
PMC6849826
AbstractArticlePDF–2.7M
11.
Uric acid enhances longevity and endurance and protects the brain against ischemia
Roy G. Cutler, Simonetta Camandola, Neil H. Feldman, Jeong Seon Yoon, James B. Haran, Sandro Arguelles, Mark P. Mattson
Neurobiol Aging. Author manuscript; available in PMC 2019 Mar 11.
Published in final edited form as: Neurobiol Aging. 2019 Mar; 75: 159–168. Published online 2018 Dec 12. doi: 10.1016/j.neurobiolaging.2018.10.031
PMCID:
PMC6410356
AbstractArticlePDF–1.1M
12.
Dissociation between urate and blood pressure in mice and in people with early Parkinson's disease
Xiqun Chen, Chizoba C. Umeh, Robert E. Tainsh, Danielle D. Feng, Michael Maguire, Fuxing Zuo, Maryam Rahimian, Robert Logan, Xinliumei Wang, Alberto Ascherio, Eric A. Macklin, Emmanuel S. Buys, Michael A. Schwarzschild, Parkinson Study Group (PSG) The Safety of Urate Elevation in Parkinson's Disease (SURE-PD) investigators
EBioMedicine. 2018 Nov; 37: 259–268. Published online 2018 Nov 8. doi: 10.1016/j.ebiom.2018.10.039
PMCID:
PMC6284456
AbstractArticlePDF–1.3M
13.
Evolutionary history and metabolic insights of ancient mammalian uricases
James T. Kratzer, Miguel A. Lanaspa, Michael N. Murphy, Christina Cicerchi, Christina L. Graves, Peter A. Tipton, Eric A. Ortlund, Richard J. Johnson, Eric A. Gaucher
Proc Natl Acad Sci U S A. 2014 Mar 11; 111(10): 3763–3768. Published online 2014 Feb 18. doi: 10.1073/pnas.1320393111
PMCID:
PMC3956161
AbstractArticlePDF–1.0M
14.
Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegeneration
Xiqun Chen, Thomas C. Burdett, Cody A. Desjardins, Robert Logan, Sara Cipriani, Yuehang Xu, Michael A. Schwarzschild
Proc Natl Acad Sci U S A. 2013 Jan 2; 110(1): 300–305. Published online 2012 Dec 17. doi: 10.1073/pnas.1217296110
PMCID:
PMC3538212
AbstractArticlePDF–745K
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
Mitochondrial Phosphoproteome Revealed by an Improved IMAC Method and MS/MS/MS
Jaeick Lee, Yingda Xu, Yue Chen, Robert Sprung, Sung Chan Kim, Shanhai Xie, Yingming Zhao
Mol Cell Proteomics. Author manuscript; available in PMC 2010 Jul 13.
Published in final edited form as: Mol Cell Proteomics. 2007 Apr; 6(4): 669–676. Published online 2007 Jan 5. doi: 10.1074/mcp.M600218-MCP200
PMCID:
PMC2902983
AbstractArticlePDF–392K
17.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K
18.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M
19.
Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes
Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki
Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100
PMCID:
PMC310980
AbstractArticlePDF–1.4M
20.
GenePaint.org: an atlas of gene expression patterns in the mouse embryo
Axel Visel, Christina Thaller, Gregor Eichele
Nucleic Acids Res. 2004 Jan 1; 32(Database issue): D552–D556. doi: 10.1093/nar/gkh029
PMCID:
PMC308763
AbstractArticlePDF–253K

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