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Select item 85900741.

Rise of cGMP by partial phosphodiesterase-3A degradation enhances cardioprotection during hypoxia

Nadja I. Bork, Anna Kuret, Melanie Cruz Santos, Cristina E. Molina, Beate Reiter, Hermann Reichenspurner, Andreas Friebe, Boris V. Skryabin, Timofey S. Rozhdestvensky, Michaela Kuhn, Robert Lukowski, Viacheslav O. Nikolaev

Redox Biol. 2021 Dec; 48: 102179. Published online 2021 Nov 6. doi: 10.1016/j.redox.2021.102179

PMCID:: PMC8590074

Abstract Article PDF–6.7M

Select item 79387702.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 66710703.

cGMP Produced by NO-Sensitive Guanylyl Cyclase Essentially Contributes to Inflammatory and Neuropathic Pain by Using Targets Different from cGMP-Dependent Protein Kinase I

Achim Schmidtko, Wei Gao, Peter König, Sandra Heine, Roberto Motterlini, Peter Ruth, Jens Schlossmann, Doris Koesling, Ellen Niederberger, Irmgard Tegeder, Andreas Friebe, Gerd Geisslinger

J Neurosci. 2008 Aug 20; 28(34): 8568–8576. doi: 10.1523/JNEUROSCI.2128-08.2008

PMCID:: PMC6671070

Abstract Article PDF–578K

Select item 61914454.

A shear-dependent NO-cGMP-cGKI cascade in platelets acts as an auto-regulatory brake of thrombosis

Lai Wen, Susanne Feil, Markus Wolters, Martin Thunemann, Frank Regler, Kjestine Schmidt, Andreas Friebe, Marcus Olbrich, Harald Langer, Meinrad Gawaz, Cor de Wit, Robert Feil

Nat Commun. 2018; 9: 4301. Published online 2018 Oct 16. doi: 10.1038/s41467-018-06638-8

Correction in:: Nat Commun. 2018; 9: 4969.

PMCID:: PMC6191445

Abstract Article PDF–2.0M

Select item 54309815.

Hypertension reduces soluble guanylyl cyclase expression in the mouse aorta via the Notch signaling pathway

Catarina Rippe, Baoyi Zhu, Katarzyna K. Krawczyk, Ed. Van Bavel, Sebastian Albinsson, Jonas Sjölund, Erik N. T. P. Bakker, Karl Swärd

Sci Rep. 2017; 7: 1334. Published online 2017 May 2. doi: 10.1038/s41598-017-01392-1

PMCID:: PMC5430981

Abstract Article PDF–4.3M

Select item 46993936.

Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice

Robrecht Thoonen, Anje Cauwels, Kelly Decaluwe, Sandra Geschka, Robert E. Tainsh, Joris Delanghe, Tino Hochepied, Lode De Cauwer, Elke Rogge, Sofie Voet, Patrick Sips, Richard H. Karas, Kenneth D. Bloch, Marnik Vuylsteke, Johannes-Peter Stasch, Johan Van de Voorde, Emmanuel S. Buys, Peter Brouckaert

Nat Commun. 2015; 6: 8482. Published online 2015 Oct 7. doi: 10.1038/ncomms9482

PMCID:: PMC4699393

Abstract Article PDF–1.1M

Select item 44551117.

Stimulation of soluble guanylyl cyclase protects against obesity by recruiting brown adipose tissue

Linda S. Hoffmann, Jennifer Etzrodt, Lena Willkomm, Abhishek Sanyal, Ludger Scheja, Alexander W.C. Fischer, Johannes-Peter Stasch, Wilhelm Bloch, Andreas Friebe, Joerg Heeren, Alexander Pfeifer

Nat Commun. 2015; 6: 7235. Published online 2015 May 26. doi: 10.1038/ncomms8235

PMCID:: PMC4455111

Abstract Article PDF–1.1M

Select item 42890948.

SOLUBLE GUANYLATE CYCLASE IS REQUIRED FOR SYSTEMIC VASODILATION BUT NOT POSITIVE INOTROPY INDUCED BY NITROXYL (HNO) in the MOUSE

Guangshuo Zhu, Dieter Groneberg, Gautam Sikka, Daijiro Hori, Mark J. Ranek, Taishi Nakamura, Eiki Takimoto, Nazareno Paolocci, Dan E. Berkowitz, Andreas Friebe, David A. Kass

Hypertension. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Hypertension. 2015 Feb; 65(2): 385–392. Published online 2014 Dec 1. doi: 10.1161/HYPERTENSIONAHA.114.04285

PMCID:: PMC4289094

Abstract Article PDF–2.2M

Select item 42673389.

Nitric oxide regulates synaptic transmission between spiny projection neurons

Yotam Sagi, Myriam Heiman, Jayms D. Peterson, Sergei Musatov, Mariangela Scarduzio, Stephen M. Logan, Michael G. Kaplitt, Dalton J. Surmeier, Nathaniel Heintz, Paul Greengard

Proc Natl Acad Sci U S A. 2014 Dec 9; 111(49): 17636–17641. Published online 2014 Nov 20. doi: 10.1073/pnas.1420162111

Correction in:: Proc Natl Acad Sci U S A. 2015 Apr 7; 112(14): E1811.

PMCID:: PMC4267338

Abstract Article PDF–1.3M

Select item 426438210.

Pressure-overload induced subcellular re-localization/oxidation of soluble guanylate cyclase in the heart modulates enzyme stimulation

Emily J. Tsai, Yuchuan Liu, Norimichi Koitabashi, Djahida Bedja, Thomas Danner, Jean-Francois Jasmin, Michael P. Lisanti, Andreas Friebe, Eiki Takimoto, David A. Kass

Circ Res. Author manuscript; available in PMC 2014 Dec 12.

Published in final edited form as: Circ Res. 2012 Jan 20; 110(2): 295–303. Published online 2011 Nov 17. doi: 10.1161/CIRCRESAHA.111.259242

PMCID:: PMC4264382

Abstract Article PDF–1.8M

Select item 403775511.

Endothelium-Derived Nitric Oxide Supports Renin Cell Recruitment Through the Nitric Oxide–Sensitive Guanylate Cyclase Pathway

Björn Neubauer, Katharina Machura, Ramona Kettl, Maria Luisa S. Sequeira Lopez, Andreas Friebe, Armin Kurtz

Hypertension. Author manuscript; available in PMC 2014 May 29.

Published in final edited form as: Hypertension. 2013 Feb; 61(2): 400–407. Published online 2013 Jan 7. doi: 10.1161/HYPERTENSIONAHA.111.00221

PMCID:: PMC4037755

Abstract Article PDF–1.2M

Select item 393637312.

Correlation of cellular expression with function of NO-sensitive guanylyl cyclase in the murine lower urinary tract

Barbara Lies, Dieter Groneberg, Andreas Friebe

J Physiol. 2013 Nov 1; 591(Pt 21): 5365–5375. Published online 2013 Sep 9. doi: 10.1113/jphysiol.2013.262410

PMCID:: PMC3936373

Abstract Article PDF–1.6M

Select item 386641513.

Soluble Guanylate Cyclase Generation of cGMP Regulates Migration of MGE Neurons

Shyamali Mandal, Amelia Stanco, Emmanuel S. Buys, Grigori Enikolopov, John L. R. Rubenstein

J Neurosci. 2013 Oct 23; 33(43): 16897–16914. doi: 10.1523/JNEUROSCI.1871-13.2013

PMCID:: PMC3866415

Abstract Article PDF–6.2M

Select item 357753414.

Preserved fertility despite erectile dysfunction in mice lacking the nitric oxide receptor

Dieter Groneberg, Barbara Lies, Peter König, Ronald Jäger, Andreas Friebe

J Physiol. 2013 Jan 15; 591(Pt 2): 491–502. Published online 2012 Nov 5. doi: 10.1113/jphysiol.2012.245555

PMCID:: PMC3577534

Abstract Article PDF–1.8M

Select item 318633815.

Biphasic roles for soluble guanylyl cyclase (sGC) in platelet activation

Guoying Zhang, Binggang Xiang, Anping Dong, Radek C. Skoda, Alan Daugherty, Susan S. Smyth, Xiaoping Du, Zhenyu Li

Blood. 2011 Sep 29; 118(13): 3670–3679. Prepublished online 2011 Jul 29. doi: 10.1182/blood-2011-03-341107

PMCID:: PMC3186338

Abstract Article

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253417.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 275779818.

C-type natriuretic peptide (CNP) is a bifurcation factor for sensory neurons

Hannes Schmidt, Agne Stonkute, René Jüttner, Doris Koesling, Andreas Friebe, Fritz G. Rathjen

Proc Natl Acad Sci U S A. 2009 Sep 29; 106(39): 16847–16852. Published online 2009 Sep 17. doi: 10.1073/pnas.0906571106

PMCID:: PMC2757798

Abstract Article PDF–1.9M

Select item 272421019.

sGCα₁β₁ attenuates cardiac dysfunction and mortality in murine inflammatory shock models

Emmanuel S. Buys, Anje Cauwels, Michael J. Raher, Jonathan J. Passeri, Ion Hobai, Sharon M. Cawley, Kristen M. Rauwerdink, Helene Thibault, Patrick Y. Sips, Robrecht Thoonen, Marielle Scherrer-Crosbie, Fumito Ichinose, Peter Brouckaert, Kenneth D. Bloch

Am J Physiol Heart Circ Physiol. 2009 Aug; 297(2): H654–H663. Published online 2009 Jun 5. doi: 10.1152/ajpheart.00367.2009

PMCID:: PMC2724210

Abstract Article

Select item 270368920.

Phosphodiesterase 5 Restricts NOS3/Soluble Guanylate Cyclase signaling to L-type Ca²⁺ current in Cardiac Myocytes

Honglan Wang, Mark J Kohr, Christopher J Traynham, Mark T Ziolo

J Mol Cell Cardiol. Author manuscript; available in PMC 2010 Aug 1.

Published in final edited form as: J Mol Cell Cardiol. 2009 Aug; 47(2): 304–314. Published online 2009 Apr 1. doi: 10.1016/j.yjmcc.2009.03.021

PMCID:: PMC2703689

Abstract Article PDF–955K

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