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Select item 108696951.

¹H NMR metabolomics insights into comparative diabesity in male and female zebrafish and the antidiabetic activity of DL-limonene

Khaled Benchoula, Christopher J. Serpell, Ahmed Mediani, Abdulaziz Albogami, Norazlan Mohmad Misnan, Nor Hadiani Ismail, Ishwar S. Parhar, Satoshi Ogawa, Wong Eng Hwa

Sci Rep. 2024; 14: 3823. Published online 2024 Feb 15. doi: 10.1038/s41598-023-45608-z

PMCID:: PMC10869695

Abstract Article PDF–8.4M

Select item 102506792.

Attenuated glucose uptake promotes catabolic metabolism through activated AMPK signaling and impaired insulin signaling in zebrafish

Longwei Xi, Gang Zhai, Yulong Liu, Yulong Gong, Qisheng Lu, Zhimin Zhang, Haokun Liu, Junyan Jin, Xiaoming Zhu, Zhan Yin, Shouqi Xie, Dong Han

Front Nutr. 2023; 10: 1187283. Published online 2023 May 26. doi: 10.3389/fnut.2023.1187283

PMCID:: PMC10250679

Abstract Article PDF–3.3M

Select item 101385853.

Type I Diabetes in Zebrafish Reduces Sperm Quality and Increases Insulin and Glucose Transporter Transcripts

Patrícia Diogo, Gil Martins, Márcio Simão, Ana Marreiros, Ana Catarina Eufrásio, Elsa Cabrita, Paulo Jorge Gavaia

Int J Mol Sci. 2023 Apr; 24(8): 7035. Published online 2023 Apr 11. doi: 10.3390/ijms24087035

PMCID:: PMC10138585

Abstract Article PDF–2.6M

Select item 99725784.

Enhanced insulin activity achieved in VDRa/b ablation zebrafish

Ruolan Liu, Yao Lu, Xuyan Peng, Jingyi Jia, Yonglin Ruan, Shengchi Shi, Tingting Shu, Tianhui Li, Xia Jin, Gang Zhai, Jiangyan He, Qiyong Lou, Zhan Yin

Front Endocrinol (Lausanne) 2023; 14: 1054665. Published online 2023 Feb 13. doi: 10.3389/fendo.2023.1054665

PMCID:: PMC9972578

Abstract Article PDF–3.1M

Select item 99590615.

A New In Vivo Zebrafish Bioassay Evaluating Liver Steatosis Identifies DDE as a Steatogenic Endocrine Disruptor, Partly through SCD1 Regulation

Hélène Le Mentec, Emmanuelle Monniez, Antoine Legrand, Céline Monvoisin, Dominique Lagadic-Gossmann, Normand Podechard

Int J Mol Sci. 2023 Feb; 24(4): 3942. Published online 2023 Feb 15. doi: 10.3390/ijms24043942

PMCID:: PMC9959061

Abstract Article PDF–10M

Select item 97928926.

Loss of glyoxalase 2 alters the glucose metabolism in zebrafish

Christoph Tobias Tabler, Elisabeth Lodd, Katrin Bennewitz, Chiara Simone Middel, Vanessa Erben, Hannes Ott, Tanja Poth, Thomas Fleming, Jakob Morgenstern, Ingrid Hausser, Carsten Sticht, Gernot Poschet, Julia Szendroedi, Peter Paul Nawroth, Jens Kroll

Redox Biol. 2023 Feb; 59: 102576. Published online 2022 Dec 14. doi: 10.1016/j.redox.2022.102576

PMCID:: PMC9792892

Abstract Article PDF–12M

Select item 94897017.

Glucocorticoid receptor activation reduces food intake independent of hyperglycemia in zebrafish

Niepukolie Nipu, Femilarani Antomagesh, Erin Faught, Mathilakath M. Vijayan

Sci Rep. 2022; 12: 15677. Published online 2022 Sep 20. doi: 10.1038/s41598-022-19572-z

PMCID:: PMC9489701

Abstract Article PDF–4.0M

Select item 88109048.

CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations

Ida Höijer, Anastasia Emmanouilidou, Rebecka Östlund, Robin van Schendel, Selma Bozorgpana, Marcel Tijsterman, Lars Feuk, Ulf Gyllensten, Marcel den Hoed, Adam Ameur

Nat Commun. 2022; 13: 627. Published online 2022 Feb 2. doi: 10.1038/s41467-022-28244-5

PMCID:: PMC8810904

Abstract Article PDF–1.1M

Select item 84562089.

Reduced Acrolein Detoxification in akr1a1a Zebrafish Mutants Causes Impaired Insulin Receptor Signaling and Microvascular Alterations

Haozhe Qi, Felix Schmöhl, Xiaogang Li, Xin Qian, Christoph T. Tabler, Katrin Bennewitz, Carsten Sticht, Jakob Morgenstern, Thomas Fleming, Nadine Volk, Ingrid Hausser, Elena Heidenreich, Rüdiger Hell, Peter Paul Nawroth, Jens Kroll

Adv Sci (Weinh) 2021 Sep; 8(18): 2101281. Published online 2021 Jul 18. doi: 10.1002/advs.202101281

PMCID:: PMC8456208

Abstract Article PDF–13M

Select item 780947210.

Stimulation of hepatocarcinogenesis by activated cholangiocytes via Il17a/f1 pathway in kras transgenic zebrafish model

Mohamed Helal, Chuan Yan, Zhiyuan Gong

Sci Rep. 2021; 11: 1372. Published online 2021 Jan 14. doi: 10.1038/s41598-020-80621-6

Correction in:: Sci Rep. 2021; 11: 13223.

PMCID:: PMC7809472

Abstract Article PDF–13M

Select item 773403211.

Identification of Potentially Relevant Genes for Excessive Exercise-Induced Pathological Cardiac Hypertrophy in Zebrafish

Zuoqiong Zhou, Lan Zheng, Changfa Tang, Zhanglin Chen, Runkang Zhu, Xiyang Peng, Xiushan Wu, Ping Zhu

Front Physiol. 2020; 11: 565307. Published online 2020 Nov 30. doi: 10.3389/fphys.2020.565307

PMCID:: PMC7734032

Abstract Article PDF–3.7M

Select item 752479912.

Vitamin D deficiency serves as a precursor to stunted growth and central adiposity in zebrafish

Megan M. Knuth, Debabrata Mahapatra, Dereje Jima, Debin Wan, Bruce D. Hammock, Mac Law, Seth W. Kullman

Sci Rep. 2020; 10: 16032. Published online 2020 Sep 29. doi: 10.1038/s41598-020-72622-2

PMCID:: PMC7524799

Abstract Article PDF–3.5M

Select item 704709713.

Generation of Novel Genetic Models to Dissect Resistance to Thyroid Hormone Receptor α in Zebrafish

Cho Rong Han, Erik Holmsen, Blake Carrington, Kevin Bishop, Yuelin Jack Zhu, Matthew Starost, Paul Meltzer, Raman Sood, Paul Liu, Sheue-yann Cheng

Thyroid. February 2020; 30(2): 314–328. Published online 2020 Feb 14. doi: 10.1089/thy.2019.0598

PMCID:: PMC7047097

Abstract Article PDF–1.1M

Select item 701462414.

Inhibition of methyltransferase activity of enhancer of zeste 2 leads to enhanced lipid accumulation and altered chromatin status in zebrafish

Marjo J. den Broeder, Jarle Ballangby, Leonie M. Kamminga, Peter Aleström, Juliette Legler, Leif C. Lindeman, Jorke H. Kamstra

Epigenetics Chromatin. 2020; 13: 5. Published online 2020 Feb 12. doi: 10.1186/s13072-020-0329-y

PMCID:: PMC7014624

Abstract Article PDF–5.7M

Select item 700639915.

RNA-Seq reveals differential expression profiles and functional annotation of genes involved in retinal degeneration in Pde6c mutant Danio rerio

Madhu Sudhana Saddala, Anton Lennikov, Adam Bouras, Hu Huang

BMC Genomics. 2020; 21: 132. Published online 2020 Feb 7. doi: 10.1186/s12864-020-6550-z

PMCID:: PMC7006399

Abstract Article PDF–2.2M

Select item 641634716.

Corosolic acid isolated from Eriobotrya japonica leaves reduces glucose level in human hepatocellular carcinoma cells, zebrafish and rats

Shuwen Xu, Gang Wang, Wei Peng, Yandi Xu, Yu Zhang, Ying Ge, Yue Jing, Zhunan Gong

Sci Rep. 2019; 9: 4388. Published online 2019 Mar 13. doi: 10.1038/s41598-019-40934-7

PMCID:: PMC6416347

Abstract Article PDF–4.6M

Select item 599197617.

Distant insulin signaling regulates vertebrate pigmentation through the sheddase Bace2

Yan M. Zhang, Milena A. Zimmer, Talia Guardia, Scott J. Callahan, Chandrani Mondal, Julie Di Martino, Toshimitsu Takagi, Myles Fennell, Ralph Garippa, Nathaniel R. Campbell, Jose Javier Bravo-Cordero, Richard M. White

Dev Cell. Author manuscript; available in PMC 2019 Jun 4.

Published in final edited form as: Dev Cell. 2018 Jun 4; 45(5): 580–594.e7. Published online 2018 May 24. doi: 10.1016/j.devcel.2018.04.025

PMCID:: PMC5991976

Abstract Article PDF–1.7M

Select item 598972918.

Insulin resistance in cavefish as an adaptation to a nutrient-limited environment

Misty R. Riddle, Ariel C. Aspiras, Karin Gaudenz, Robert Peuß, Jenny Y. Sung, Brian Martineau, Megan Peavey, Andrew C. Box, Julius A. Tabin, Suzanne McGaugh, Richard Borowsky, Clifford J. Tabin, Nicolas Rohner

Nature. Author manuscript; available in PMC 2018 Sep 29.

Published in final edited form as: Nature. 2018 Mar 29; 555(7698): 647–651. Published online 2018 Mar 21. doi: 10.1038/nature26136

PMCID:: PMC5989729

Abstract Article PDF–2.8M

Select item 595409019.

Inhibited Carnitine Synthesis Causes Systemic Alteration of Nutrient Metabolism in Zebrafish

Jia-Min Li, Ling-Yu Li, Xuan Qin, Pascal Degrace, Laurent Demizieux, Samwel M. Limbu, Xin Wang, Mei-Ling Zhang, Dong-Liang Li, Zhen-Yu Du

Front Physiol. 2018; 9: 509. Published online 2018 May 9. doi: 10.3389/fphys.2018.00509

PMCID:: PMC5954090

Abstract Article PDF–1.9M

Select item 582020220.

Oxidative stress-dependent MMP-13 activity underlies glucose neurotoxicity

Ashley L. Waldron, Patricia A. Schroder, Kelly L. Bourgon, Jessie K. Bolduc, James L. Miller, Adriana D. Pellegrini, Amanda L. Dubois, Magdalena Blaszkiewicz, Kristy L. Townsend, Sandra Rieger

J Diabetes Complications. Author manuscript; available in PMC 2019 Mar 1.

Published in final edited form as: J Diabetes Complications. 2018 Mar; 32(3): 249–257. Published online 2017 Dec 6. doi: 10.1016/j.jdiacomp.2017.11.012