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Select item 114922401.

Physics-Based Protein Networks Might Recover Effectful Mutations—a Case Study on Cathepsin G

Fabian Schuhmann, Heloisa N. Bordallo, Weria Pezeshkian

J Phys Chem B. 2024 Oct 17; 128(41): 10043–10050. Published online 2024 Oct 2. doi: 10.1021/acs.jpcb.4c04140

PMCID:: PMC11492240

Abstract Article PDF–5.1M

Select item 110287272.

Cathepsin G-mediated proteolytic degradation of MHC class I molecules to facilitate immune detection of human glioblastoma cells

David Palesch, Johanna Wagner, Annika Meid, Nicole Molenda, Marcin Sienczyk, Jutta Burkhardt, Jan Münch, Lea Prokop, Stefan Stevanovic, Mike-Andrew Westhoff, Marc-Eric Halatsch, Christian Rainer Wirtz, Michal Zimecki, Timo Burster

Cancer Immunol Immunother. 2016 Mar; 65(3): 283–291. Published online 2016 Feb 2. doi: 10.1007/s00262-016-1798-5

PMCID:: PMC11028727

Abstract Article PDF–1.7M

Select item 108783333.

Cathepsin G promotes arteriovenous fistula maturation by positively regulating the MMP2/MMP9 pathway

Lemei Hu, Changqing Zheng, Ying Kong, Zhiqing Luo, Fengzhang Huang, Zhigang Zhu, Quhuan Li, Ming Liang

Ren Fail. 2024; 46(1): 2316269. Published online 2024 Feb 16. doi: 10.1080/0886022X.2024.2316269

PMCID:: PMC10878333

Abstract Article PDF–7.9M

Select item 101580204.

CTSG Suppresses Colorectal Cancer Progression through Negative Regulation of Akt/mTOR/Bcl2 Signaling Pathway

Shixin Chan, Xu Wang, Zhenglin Wang, Youwen Du, Xiaomin Zuo, Jiajie Chen, Rui Sun, Qing Zhang, Li Lin, Yang Yang, Zhen Yu, Hu Zhao, Huabing Zhang, Wei Chen

Int J Biol Sci. 2023; 19(7): 2220–2233. Published online 2023 Apr 17. doi: 10.7150/ijbs.82000

PMCID:: PMC10158020

Abstract Article PDF–8.6M

Select item 81766355.

Cathepsin G Degrades Staphylococcus aureus Biofilms

Jeffrey S Kavanaugh, Kevin G Leidal, William M Nauseef, Alexander R Horswill

J Infect Dis. 2021 Jun 1; 223(11): 1865–1869. Published online 2020 Sep 30. doi: 10.1093/infdis/jiaa612

PMCID:: PMC8176635

Abstract Article PDF–2.7M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80787287.

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics

Alexandra Naba, Oliver M. T. Pearce, Amanda Del Rosario, Duanduan Ma, Huiming Ding, Vinothini Rajeeve, Pedro R. Cutillas, Frances R. Balkwill, Richard O. Hynes

J Proteome Res. Author manuscript; available in PMC 2021 Apr 27.

Published in final edited form as: J Proteome Res. 2017 Aug 4; 16(8): 3083–3091. Published online 2017 Jul 19. doi: 10.1021/acs.jproteome.7b00191

PMCID:: PMC8078728

Abstract Article PDF–2.1M

Select item 74273278.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 72617919.

Local structural plasticity of the Staphylococcus aureus evasion protein EapH1 enables engagement with multiple neutrophil serine proteases

Timothy J. Herdendorf, Daphne A. C. Stapels, Suzan H. M. Rooijakkers, Brian V. Geisbrecht

J Biol Chem. 2020 May 29; 295(22): 7753–7762. Published online 2020 Apr 17. doi: 10.1074/jbc.RA120.013601

PMCID:: PMC7261791

Abstract Article PDF–2.4M

Select item 716998310.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 706296211.

Cathepsin G—Not Only Inflammation: The Immune Protease Can Regulate Normal Physiological Processes

Tatyana S. Zamolodchikova, Svetlana M. Tolpygo, Elena V. Svirshchevskaya

Front Immunol. 2020; 11: 411. Published online 2020 Mar 3. doi: 10.3389/fimmu.2020.00411

PMCID:: PMC7062962

Article PDF–492K

Select item 706020412.

Cathepsin g Degrades Both Glycosylated and Unglycosylated Regions of Lubricin, a Synovial Mucin

Shan Huang, Kristina A. Thomsson, Chunsheng Jin, Sally Alweddi, André Struglics, Ola Rolfson, Lena I. Björkman, Sebastian Kalamajski, Tannin A. Schmidt, Gregory D. Jay, Roman Krawetz, Niclas G. Karlsson, Thomas Eisler

Sci Rep. 2020; 10: 4215. Published online 2020 Mar 6. doi: 10.1038/s41598-020-61161-5

Correction in:: Sci Rep. 2021; 11: 4238.

PMCID:: PMC7060204

Abstract Article PDF–2.2M

Select item 681279613.

The N125S polymorphism in the cathepsin G gene (rs45567233) is associated with susceptibility to osteomyelitis in a Spanish population

Laura Pérez-Is, Marcos G. Ocaña, A. Hugo Montes, José A. Carton, Victoria Álvarez, Álvaro Meana, Joshua Fierer, Eulalia Valle-Garay, Víctor Asensi

PLoS One. 2019; 14(10): e0220022. Published online 2019 Oct 24. doi: 10.1371/journal.pone.0220022

PMCID:: PMC6812796

Abstract Article PDF–1.0M

Select item 644057714.

Isoform-specific GSK3A activity is negatively correlated with human sperm motility

M J Freitas, J V Silva, C Brothag, B Regadas-Correia, M Fardilha, S Vijayaraghavan

Mol Hum Reprod. 2019 Apr; 25(4): 171–183. Published online 2019 Mar 2. doi: 10.1093/molehr/gaz009

PMCID:: PMC6440577

Abstract Article PDF–1.0M

Select item 637200715.

Cathepsin G cleaves and activates IL-36γ and promotes the inflammation of psoriasis

Jing Guo, Jie Tu, YingYing Hu, GuoXin Song, ZhiQiang Yin

Drug Des Devel Ther. 2019; 13: 581–588. Published online 2019 Feb 8. doi: 10.2147/DDDT.S194765

PMCID:: PMC6372007

Abstract Article PDF–1.6M

Select item 620219016.

Neutrophil Extracellular Traps Induce Endothelial Cell Activation and Tissue Factor Production through Interleukin-1α and Cathepsin G

Eduardo J. Folco, Thomas L. Mawson, Amélie Vromman, Breno Bernardes-Souza, Grégory Franck, Oscar Persson, Momotaro Nakamura, Gail Newton, Francis W. Luscinskas, Peter Libby

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2019 Aug 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2018 Aug; 38(8): 1901–1912. doi: 10.1161/ATVBAHA.118.311150

PMCID:: PMC6202190

Abstract Article PDF–1.9M

Select item 584953417.

Genome-wide CRISPR-Cas9 screen identifies leukemia-specific dependence on a pre-mRNA metabolic pathway regulated by DCPS

Takuji Yamauchi, Takeshi Masuda, Matthew C. Canver, Michael Seiler, Yuichiro Semba, Mohammad Shboul, Mohammed Al-Raqad, Manami Maeda, Vivien A. C. Schoonenberg, Mitchel A. Cole, Claudio Macias-Trevino, Yuichi Ishikawa, Qiuming Yao, Michitaka Nakano, Fumio Arai, Stuart H. Orkin, Bruno Reversade, Silvia Buonamici, Luca Pinello, Koichi Akashi, Daniel E. Bauer, Takahiro Maeda

Cancer Cell. Author manuscript; available in PMC 2019 Mar 12.

Published in final edited form as: Cancer Cell. 2018 Mar 12; 33(3): 386–400.e5. Published online 2018 Feb 22. doi: 10.1016/j.ccell.2018.01.012

PMCID:: PMC5849534

Abstract Article PDF–1.1M

Select item 576285118.

Caspase-4 activation by a bacterial surface protein is mediated by cathepsin G in human gingival fibroblasts

Hye-Kyoung Jun, Young-Jung Jung, Suk Ji, Sun-Jin An, Bong-Kyu Choi

Cell Death Differ. 2018 Feb; 25(2): 380–391. Published online 2017 Oct 27. doi: 10.1038/cdd.2017.167

PMCID:: PMC5762851

Abstract Article PDF–3.2M

Select item 554350919.

Insulin‐like growth factor‐1 signaling is responsible for cathepsin G‐induced aggregation of breast cancer MCF‐7 cells

Riyo Morimoto‐Kamata, Satoru Yui

Cancer Sci. 2017 Aug; 108(8): 1574–1583. Published online 2017 Jun 21. doi: 10.1111/cas.13286

PMCID:: PMC5543509

Abstract Article PDF–1.9M

Select item 553161120.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

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