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Select item 88421651.

CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system

Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar

Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629

PMCID:: PMC8842165

Abstract Article PDF–3.0M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 63383663.

Variants in FAT1 and COL9A1 genes in male population with or without substance use to assess the risk factors for oral malignancy

Chia-Min Chung, Chung-Chieh Hung, Chien-Hung Lee, Chi-Pin Lee, Ka-Wo Lee, Mu-Kuan Chen, Kun-Tu Yeh, Ying-Chin Ko

PLoS One. 2019; 14(1): e0210901. Published online 2019 Jan 18. doi: 10.1371/journal.pone.0210901

PMCID:: PMC6338366

Abstract Article PDF–611K

Select item 63038684.

Whole-genome sequencing reveals novel genes in ossification of the posterior longitudinal ligament of the thoracic spine in the Chinese population

Chen Liang, Peng Wang, Xiao Liu, Chenlong Yang, Yunlong Ma, Lei Yong, Bin Zhu, Xiaoguang Liu, Zhongjun Liu

J Orthop Surg Res. 2018; 13: 324. Published online 2018 Dec 22. doi: 10.1186/s13018-018-1022-8

PMCID:: PMC6303868

Abstract Article PDF–1.1M

Select item 55593065.

A genome-wide CRISPR screen identifies genes critical for resistance to FLT3 inhibitor AC220

Panpan Hou, Chao Wu, Yuchen Wang, Rui Qi, Dheeraj Bhavanasi, Zhixiang Zuo, Cedric Dos Santos, Shuliang Chen, Yu Chen, Hong Zheng, Hong Wang, Alexander Perl, Deyin Guo, Jian Huang

Cancer Res. Author manuscript; available in PMC 2018 Aug 15.

Published in final edited form as: Cancer Res. 2017 Aug 15; 77(16): 4402–4413. Published online 2017 Jun 16. doi: 10.1158/0008-5472.CAN-16-1627

PMCID:: PMC5559306

Abstract Article PDF–885K

Select item 55316116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 51266617.

Structural insight for chain selection and stagger control in collagen

Sergei P. Boudko, Hans Peter Bächinger

Sci Rep. 2016; 6: 37831. Published online 2016 Nov 29. doi: 10.1038/srep37831

PMCID:: PMC5126661

Abstract Article PDF–1.4M

Select item 46172118.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 43617359.

COL9A1 Gene Polymorphism Is Associated with Kashin-Beck Disease in a Northwest Chinese Han Population

Xiaowei Shi, Feng Zhang, Aili Lv, Yan Wen, Xiong Guo

PLoS One. 2015; 10(3): e0120365. Published online 2015 Mar 16. doi: 10.1371/journal.pone.0120365

PMCID:: PMC4361735

Abstract Article PDF–514K

Select item 422362710.

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver

Alexandra Naba, Karl R Clauser, Charles A Whittaker, Steven A Carr, Kenneth K Tanabe, Richard O Hynes

BMC Cancer. 2014; 14: 518. Published online 2014 Jul 18. doi: 10.1186/1471-2407-14-518

PMCID:: PMC4223627

Abstract Article PDF–1.5M

Select item 421198411.

Association of Reduced Type IX Collagen Gene Expression in Human Osteoarthritic Chondrocytes With Epigenetic Silencing by DNA Hypermethylation

Kei Imagawa, María C de Andrés, Ko Hashimoto, Eiji Itoi, Miguel Otero, Helmtrud I Roach, Mary B Goldring, Richard O C Oreffo

Arthritis Rheumatol. 2014 Nov; 66(11): 3040–3051. Published online 2014 Oct 26. doi: 10.1002/art.38774

PMCID:: PMC4211984

Abstract Article PDF–637K

Select item 355736912.

Type IX collagen gene mutations can result in multiple epiphyseal dysplasia that is associated with osteochondritis dissecans and a mild myopathy

Gail C Jackson, Dominique Marcus-Soekarman, Irene Stolte-Dijkstra, Aad Verrips, Jacqueline A Taylor, Michael D Briggs

Am J Med Genet A. 2010 Apr; 152A(4): 863–869. Published online 2012 Mar 26. doi: 10.1002/ajmg.a.33240

PMCID:: PMC3557369

Abstract Article PDF–202K

Select item 353176713.

The NC2 Domain of Type IX Collagen Determines the Chain Register of the Triple Helix

Sergei P. Boudko, Hans Peter Bächinger

J Biol Chem. 2012 Dec 28; 287(53): 44536–44545. Published online 2012 Nov 6. doi: 10.1074/jbc.M112.417543

PMCID:: PMC3531767

Abstract Article PDF–1.4M

Select item 318640814.

Type IX Collagen Interacts with Fibronectin Providing an Important Molecular Bridge in Articular Cartilage

Philippa Parsons, Sophie J. Gilbert, Anne Vaughan-Thomas, David A. Sorrell, Rebecca Notman, Mark Bishop, Anthony J. Hayes, Deborah J. Mason, Victor C. Duance

J Biol Chem. 2011 Oct 7; 286(40): 34986–34997. Published online 2011 Jul 15. doi: 10.1074/jbc.M111.238188

PMCID:: PMC3186408

Abstract Article PDF–2.2M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 294516816.

Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators

Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452

PMCID:: PMC2945168

Abstract Article PDF–153K

Select item 291127217.

The NC2 Domain of Collagen IX Provides Chain Selection and Heterotrimerization

Sergei P. Boudko, Keith D. Zientek, Jesse Vance, Jessica L. Hacker, Jürgen Engel, Hans Peter Bächinger

J Biol Chem. 2010 Jul 30; 285(31): 23721–23731. Published online 2010 May 27. doi: 10.1074/jbc.M110.128405

PMCID:: PMC2911272

Abstract Article PDF–3.3M

Select item 289646418.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Abstract Article PDF–2.4M

Select item 277583219.

Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani

Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014

PMCID:: PMC2775832

Abstract Article PDF–2.8M

Select item 267305520.

STRUCTURAL AND FUNCTIONAL CHARACTERISATION OF RECOMBINANT MATRILIN-3 A-DOMAIN AND IMPLICATIONS FOR HUMAN GENETIC BONE DISEASES

Maryline Fresquet, Thomas A. Jowitt, Joni Ylöstalo, Paul Coffey, Roger S. Meadows, Leena Ala-Kokko, David J. Thornton, Michael D. Briggs

J Biol Chem. Author manuscript; available in PMC 2009 Apr 24.

Published in final edited form as: J Biol Chem. 2007 Nov 30; 282(48): 34634–34643. Published online 2007 Sep 18. doi: 10.1074/jbc.M705301200

PMCID:: PMC2673055

Abstract Article PDF–1.3M

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