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Select item 107436161.

HIV-1 Tat Induces Dysregulation of PGC1-Alpha and Sirtuin 3 Expression in Neurons: The Role of Mitochondrial Biogenesis in HIV-Associated Neurocognitive Disorder (HAND)

Izchel Figarola-Centurión, Martha Escoto-Delgadillo, Gracia Viviana González-Enríquez, Juan Ernesto Gutiérrez-Sevilla, Eduardo Vázquez-Valls, Jhonathan Cárdenas-Bedoya, Blanca Miriam Torres-Mendoza

Int J Mol Sci. 2023 Dec; 24(24): 17566. Published online 2023 Dec 17. doi: 10.3390/ijms242417566

PMCID:: PMC10743616

Abstract Article PDF–1.6M

Select item 107178132.

The effects of running exercise on oxidative capacity and PGC-1α mRNA levels in the soleus muscle of rats with metabolic syndrome

Fumiko Nagatomo, Hidemi Fujino, Hiroyo Kondo, Motoki Kouzaki, Ning Gu, Isao Takeda, Kinsuke Tsuda, Akihiko Ishihara

J Physiol Sci. 2012 Mar; 62(2): 105–114. Published online 2012 Jan 11. doi: 10.1007/s12576-011-0188-1

PMCID:: PMC10717813

Abstract Article PDF–677K

Select item 106442923.

Cooling of male rat skeletal muscle during endurance‐like contraction attenuates contraction‐induced PGC‐1α mRNA expression

Daisuke Hoshino, Ryota Wada, Yutaro Mori, Reo Takeda, Yudai Nonaka, Ryotaro Kano, Ryo Takagi, Yutaka Kano

Physiol Rep. 2023 Nov; 11(21): e15867. Published online 2023 Nov 14. doi: 10.14814/phy2.15867

PMCID:: PMC10644292

Abstract Article PDF–3.1M

Select item 102758234.

Role of Estrogen-Related Receptor γ and PGC-1α/SIRT3 Pathway in Early Brain Injury After Subarachnoid Hemorrhage

Yong Guo, Yongmei Hu, Yi Huang, Lei Huang, Hideki Kanamaru, Yushin Takemoto, Hao Li, Dujuan Li, Jianjun Gu, John H. Zhang

Neurotherapeutics. 2023 Apr; 20(3): 822–837. Published online 2022 Dec 8. doi: 10.1007/s13311-022-01330-8

Correction in:: Neurotherapeutics. 2023 Apr; 20(3): 908.

PMCID:: PMC10275823

Abstract Article PDF–8.1M

Select item 101223815.

The mechanism by which miR-494-3p regulates PGC1-α-mediated inhibition of mitophagy in cardiomyocytes and alleviation of myocardial ischemia—reperfusion injury

Ninghui Mu, Tong Zhang, Ying Zhu, Bingtuan Lu, Qi Zheng, Jinlan Duan

BMC Cardiovasc Disord. 2023; 23: 204. Published online 2023 Apr 21. doi: 10.1186/s12872-023-03226-7

PMCID:: PMC10122381

Abstract Article PDF–2.1M

Select item 93222556.

NF-κB p65 Attenuates Cardiomyocyte PGC-1α Expression in Hypoxia

Inna Rabinovich-Nikitin, Alexandra Blant, Rimpy Dhingra, Lorrie A. Kirshenbaum, Michael P. Czubryt

Cells. 2022 Jul; 11(14): 2193. Published online 2022 Jul 13. doi: 10.3390/cells11142193

PMCID:: PMC9322255

Abstract Article PDF–2.9M

Select item 85482177.

过氧化物酶体增殖物激活受体γ共激活因子-1α在牙周炎诱发大鼠肝损伤中的作用研究

夏博园, 李艳, 丁旭, 李鑫, 刘歆婵, 于维先

Hua Xi Kou Qiang Yi Xue Za Zhi. 2021 Oct; 39(5): 518–523. Chinese. doi: 10.7518/hxkq.2021.05.004

PMCID:: PMC8548217

Abstract Article PDF–3.0M

Select item 84651188.

Renal Ischemia/Reperfusion Early Induces Myostatin and PCSK9 Expression in Rat Kidneys and HK-2 Cells

Chiara Barisione, Daniela Verzola, Silvano Garibaldi, Pier Francesco Ferrari, Giacomo Garibotto, Pietro Ameri, Bianca Pane, Giovanni Spinella, Giovanni Pratesi, Domenico Palombo

Int J Mol Sci. 2021 Sep; 22(18): 9884. Published online 2021 Sep 13. doi: 10.3390/ijms22189884

PMCID:: PMC8465118

Abstract Article PDF–7.4M

Select item 84446139.

NAD⁺ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway

Yao Zhao, Jiawei Zhang, Yaling Zheng, Yaxuan Zhang, Xiao Jie Zhang, Hongmei Wang, Yu Du, Jian Guan, Xiuzhe Wang, Jianliang Fu

J Neuroinflammation. 2021; 18: 207. Published online 2021 Sep 16. doi: 10.1186/s12974-021-02250-8

PMCID:: PMC8444613

Abstract Article PDF–4.0M

Select item 758391410.

Peroxisome Proliferator-Activated Receptor γ Coactivator 1α Activates Vascular Endothelial Growth Factor That Protects Against Neuronal Cell Death Following Status Epilepticus through PI3K/AKT and MEK/ERK Signaling

Jyun-Bin Huang, Shih-Pin Hsu, Hsiu-Yung Pan, Shang-Der Chen, Shu-Fang Chen, Tsu-Kung Lin, Xuan-Ping Liu, Jie-Hau Li, Nai-Ching Chen, Chia-Wei Liou, Chung-Yao Hsu, Hung-Yi Chuang, Yao-Chung Chuang

Int J Mol Sci. 2020 Oct; 21(19): 7247. Published online 2020 Sep 30. doi: 10.3390/ijms21197247

PMCID:: PMC7583914

Abstract Article PDF–4.9M

Select item 720248911.

Melatonin improves mitochondrial biogenesis through the AMPK/PGC1α pathway to attenuate ischemia/reperfusion-induced myocardial damage

Xueyan Qi, Jin Wang

Aging (Albany NY) 2020 Apr 30; 12(8): 7299–7312. Published online 2020 Apr 19. doi: 10.18632/aging.103078

PMCID:: PMC7202489

Abstract Article PDF–2.0M

Select item 714611012.

Exercise Training-Induced PPARβ Increases PGC-1α Protein Stability and Improves Insulin-Induced Glucose Uptake in Rodent Muscles

Ju-Sik Park, John O. Holloszy, Kijin Kim, Jin-Ho Koh

Nutrients. 2020 Mar; 12(3): 652. Published online 2020 Feb 28. doi: 10.3390/nu12030652

PMCID:: PMC7146110

Abstract Article PDF–1.9M

Select item 713827013.

Melatonin elicits protective effects on OGD/R-insulted H9c2 cells by activating PGC-1α/Nrf2 signaling

Weiwei Zhi, Kai Li, Hongbing Wang, Ming Lei, Yingqiang Guo

Int J Mol Med. 2020 May; 45(5): 1294–1304. Published online 2020 Feb 25. doi: 10.3892/ijmm.2020.4514

PMCID:: PMC7138270

Abstract Article PDF–1.1M

Select item 703141614.

The Expression of CNS-Specific PPARGC1A Transcripts Is Regulated by Hypoxia and a Variable GT Repeat Polymorphism

Selma M. Soyal, Petra Bonova, Markus Kwik, Greta Zara, Simon Auer, Cornelia Scharler, Dirk Strunk, Charity Nofziger, Markus Paulmichl, Wolfgang Patsch

Mol Neurobiol. 2020; 57(2): 752–764. Published online 2019 Aug 30. doi: 10.1007/s12035-019-01731-5