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Items: 1 to 20 of 26

1.
EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation
Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing
Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6
PMCID:
PMC8748958
AbstractArticlePDF–3.0M
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
4.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
5.
Malignant Brain Tumor Repeats: A Three-Leaved Propeller Architecture with Ligand/Peptide Binding Pockets
Wooi Koon Wang, Valentina Tereshko, Piernicola Boccuni, Donal MacGrogan, Stephen D. Nimer, Dinshaw J. Patel
Structure. Author manuscript; available in PMC 2015 Dec 29.
Published in final edited form as: Structure. 2003 Jul; 11(7): 775–789. doi: 10.1016/s0969-2126(03)00127-8
PMCID:
PMC4693639
AbstractArticlePDF–3.3M
6.
Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger
Haitao Li, Wolfgang Fischle, Wooikoon Wang, Elizabeth M. Duncan, Lena Liang, Satoko Murakami-Ishibe, C. David Allis, Dinshaw J. Patel
Mol Cell. Author manuscript; available in PMC 2015 Dec 23.
Published in final edited form as: Mol Cell. 2007 Nov 30; 28(4): 677–691. doi: 10.1016/j.molcel.2007.10.023
PMCID:
PMC4689580
AbstractArticlePDF–995K
7.
A functional deficiency of TERA/VCP/p97 contributes to impaired DNA damage repair in multiple polyglutamine diseases
Kyota Fujita, Yoko Nakamura, Tsutomu Oka, Hikaru Ito, Takuya Tamura, Kazuhiko Tagawa, Toshikazu Sasabe, Asuka Katsuta, Kazumi Motoki, Hiroki Shiwaku, Masaki Sone, Chisato Yoshida, Masahisa Katsuno, Yoshinobu Eishi, Miho Murata, J. Paul Taylor, Erich E. Wanker, Kazuteru Kono, Satoshi Tashiro, Gen Sobue, Albert R. La Spada, Hitoshi Okazawa
Nat Commun. Author manuscript; available in PMC 2015 Aug 20.
Published in final edited form as: Nat Commun. 2013; 4: 1816. doi: 10.1038/ncomms2828
PMCID:
PMC4543262
AbstractArticlePDF–2.0M
8.
The Polycomb Group Protein L3MBTL1 Represses a SMAD5-Mediated Hematopoietic Transcriptional Program in Human Pluripotent Stem Cells
Fabiana Perna, Ly P. Vu, Maria Themeli, Sonja Kriks, Ruben Hoya-Arias, Raya Khanin, Todd Hricik, Jorge Mansilla-Soto, Eirini P. Papapetrou, Ross L. Levine, Lorenz Studer, Michel Sadelain, Stephen D. Nimer
Stem Cell Reports. 2015 Apr 14; 4(4): 658–669. Published online 2015 Mar 5. doi: 10.1016/j.stemcr.2015.02.003
PMCID:
PMC4400644
AbstractArticlePDF–2.1M
9.
Meta-analysis of expression of l(3)mbt tumor-associated germline genes supports the model that a soma-to-germline transition is a hallmark of human cancers
Julia Feichtinger, Lee Larcombe, Ramsay J McFarlane
Int J Cancer. 2014 May 15; 134(10): 2359–2365. Published online 2013 Oct 31. doi: 10.1002/ijc.28577
PMCID:
PMC4166677
AbstractArticlePDF–6.5M
10.
L3MBTL1 Deficiency Directs the Differentiation of Human Embryonic Stem Cells Toward Trophectoderm
Ruben Hoya-Arias, Mark Tomishima, Fabiana Perna, Francesca Voza, Stephen D. Nimer
Stem Cells Dev. 2011 Nov; 20(11): 1889–1900. Published online 2011 Feb 22. doi: 10.1089/scd.2010.0437
PMCID:
PMC3202892
AbstractArticlePDF–1.6M
11.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
12.
Protein interactome reveals converging molecular pathways among autism disorders
Yasunari Sakai, Chad A. Shaw, Brian C. Dawson, Diana V. Dugas, Zaina Al-Mohtaseb, David E. Hill, Huda Y. Zoghbi
Sci Transl Med. Author manuscript; available in PMC 2011 Dec 8.
Published in final edited form as: Sci Transl Med. 2011 Jun 8; 3(86): 86ra49. doi: 10.1126/scitranslmed.3002166
PMCID:
PMC3169432
AbstractArticlePDF–6.0M
13.
The XLMR gene PHF8 encodes a histone H4K20/H3K9 demethylase and regulates zebrafish brain and craniofacial development
Hank H. Qi, Madathia Sarkissian, Gang-Qing Hu, Zhibin Wang, Arindam Bhattacharjee, D. Benjamin Gordon, Michelle Gonzales, Fei Lan, Pat P. Ongusaha, Maite Huarte, Nasser K. Yaghi, Huijun Lim, Benjamin A. Garcia, Leonardo Brizuela, Keji Zhao, Thomas M. Roberts, Yang Shi
Nature. Author manuscript; available in PMC 2011 Apr 7.
Published in final edited form as: Nature. 2010 Jul 22; 466(7305): 503–507. Published online 2010 Jul 11. doi: 10.1038/nature09261
PMCID:
PMC3072215
AbstractArticlePDF–2.1M
14.
L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability
Nadia Gurvich, Fabiana Perna, Andrea Farina, Francesca Voza, Silvia Menendez, Jerard Hurwitz, Stephen D. Nimer
Proc Natl Acad Sci U S A. 2010 Dec 28; 107(52): 22552–22557. Published online 2010 Dec 13. doi: 10.1073/pnas.1017092108
PMCID:
PMC3012470
AbstractArticlePDF–686K
15.
Methylation of the Retinoblastoma Tumor Suppressor by SMYD2
Louis A. Saddic, Lisandra E. West, Aaron Aslanian, John R. Yates, III, Seth M. Rubin, Or Gozani, Julien Sage
J Biol Chem. 2010 Nov 26; 285(48): 37733–37740. Published online 2010 Sep 24. doi: 10.1074/jbc.M110.137612
PMCID:
PMC2988378
AbstractArticlePDF–3.0M
16.
The MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene Repression
Lisandra E. West, Siddhartha Roy, Karin Lachmi-Weiner, Ryo Hayashi, Xiaobing Shi, Ettore Appella, Tatiana G. Kutateladze, Or Gozani
J Biol Chem. 2010 Nov 26; 285(48): 37725–37732. Published online 2010 Sep 24. doi: 10.1074/jbc.M110.139527
PMCID:
PMC2988377
AbstractArticlePDF–1.3M
17.
Depletion of L3MBTL1 promotes the erythroid differentiation of human hematopoietic progenitor cells: possible role in 20q− polycythemia vera
Fabiana Perna, Nadia Gurvich, Ruben Hoya-Arias, Omar Abdel-Wahab, Ross L. Levine, Takashi Asai, Francesca Voza, Silvia Menendez, Lan Wang, Fan Liu, Xinyang Zhao, Stephen D. Nimer
Blood. 2010 Oct 14; 116(15): 2812–2821. Prepublished online 2010 Jun 28. doi: 10.1182/blood-2010-02-270611
PMCID:
PMC2974589
AbstractArticle
18.
Histone H4 lysine 20 monomethylation promotes transcriptional repression by L3MBTL1
N Kalakonda, W Fischle, P Boccuni, N Gurvich, R Hoya-Arias, X Zhao, Y Miyata, D MacGrogan, J Zhang, JK Sims, JC Rice, SD Nimer
Oncogene. Author manuscript; available in PMC 2009 Sep 11.
Published in final edited form as: Oncogene. 2008 Jul 17; 27(31): 4293–4304. Published online 2008 Apr 14. doi: 10.1038/onc.2008.67
PMCID:
PMC2742506
AbstractArticlePDF–2.0M
19.
Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins
Patrick Trojer, Jin Zhang, Masato Yonezawa, Andreas Schmidt, Haiyan Zheng, Thomas Jenuwein, Danny Reinberg
J Biol Chem. 2009 Mar 27; 284(13): 8395–8405. doi: 10.1074/jbc.M807818200
PMCID:
PMC2659197
AbstractArticlePDF–797K
20.
PR-Set7 Establishes a Repressive trans-Tail Histone Code That Regulates Differentiation
Jennifer K. Sims, Judd C. Rice
Mol Cell Biol. 2008 Jul; 28(14): 4459–4468. Published online 2008 May 12. doi: 10.1128/MCB.00410-08
PMCID:
PMC2447116
AbstractArticlePDF–638K

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