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Items: 1 to 20 of 65

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway
Chunsik Lee, Rongyuan Chen, Guangli Sun, Xialin Liu, Xianchai Lin, Chang He, Liying Xing, Lixian Liu, Lasse D. Jensen, Anil Kumar, Harald F. Langer, Xiangrong Ren, Jianing Zhang, Lijuan Huang, Xiangke Yin, JongKyong Kim, Juanhua Zhu, Guanqun Huang, Jiani Li, Weiwei Lu, Wei Chen, Juanxi Liu, Jiaxin Hu, Qihang Sun, Weisi Lu, Lekun Fang, Shasha Wang, Haiqing Kuang, Yihan Zhang, Geng Tian, Jia Mi, Bi-Ang Kang, Masashi Narazaki, Aaron Prodeus, Luc Schoonjans, David M. Ornitz, Jean Gariepy, Guy Eelen, Mieke Dewerchin, Yunlong Yang, Jing-Song Ou, Antonio Mora, Jin Yao, Chen Zhao, Yizhi Liu, Peter Carmeliet, Yihai Cao, Xuri Li
Signal Transduct Target Ther. 2023; 8: 305. Published online 2023 Aug 18. doi: 10.1038/s41392-023-01539-9
PMCID:
PMC10435562
AbstractArticlePDF–4.9M
3.
Reducing VEGFB expression regulates the balance of glucose and lipid metabolism in mice via VEGFR1
Xu Luo, Rong-Rong Li, Yu-Qi Li, Han-Pu Yu, Hai-Ning Yu, Wen-Guo Jiang, Ya-Na Li
Mol Med Rep. 2022 Sep; 26(3): 285. Published online 2022 Jul 26. doi: 10.3892/mmr.2022.12801
PMCID:
PMC9366154
AbstractArticlePDF–7.2M
4.
Reducing VEGFB accelerates NAFLD and insulin resistance in mice via inhibiting AMPK signaling pathway
Rongrong Li, Yuqi Li, Xueling Yang, Yaorui Hu, Haining Yu, Yana Li
J Transl Med. 2022; 20: 341. Published online 2022 Jul 30. doi: 10.1186/s12967-022-03540-2
PMCID:
PMC9338666
AbstractArticlePDF–12M
5.
Knockdown of VEGFB/VEGFR1 Signaling Promotes White Adipose Tissue Browning and Skeletal Muscle Development
Mingfa Ling, Xumin Lai, Lulu Quan, Fan Li, Limin Lang, Yiming Fu, Shengchun Feng, Xin Yi, Canjun Zhu, Ping Gao, Xiaotong Zhu, Lina Wang, Gang Shu, Qingyan Jiang, Songbo Wang
Int J Mol Sci. 2022 Jul; 23(14): 7524. Published online 2022 Jul 7. doi: 10.3390/ijms23147524
PMCID:
PMC9315609
AbstractArticlePDF–2.6M
6.
VEGFB Promotes Myoblasts Proliferation and Differentiation through VEGFR1-PI3K/Akt Signaling Pathway
Mingfa Ling, Lulu Quan, Xumin Lai, Limin Lang, Fan Li, Xiaohua Yang, Yiming Fu, Shengchun Feng, Xin Yi, Canjun Zhu, Ping Gao, Xiaotong Zhu, Lina Wang, Gang Shu, Qingyan Jiang, Songbo Wang
Int J Mol Sci. 2021 Dec; 22(24): 13352. Published online 2021 Dec 12. doi: 10.3390/ijms222413352
PMCID:
PMC8707860
AbstractArticlePDF–2.7M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
Susceptibility to Cardiac Arrhythmias and Sympathetic Nerve Growth in VEGF-B Overexpressing Myocardium
Johanna Lähteenvuo, Olli-Pekka Hätinen, Antti Kuivanen, Jenni Huusko, Jussi Paananen, Markku Lähteenvuo, Jussi Nurro, Marja Hedman, Juha Hartikainen, Nihay Laham-Karam, Petri Mäkinen, Markus Räsänen, Kari Alitalo, Anthony Rosenzweig, Seppo Ylä-Herttuala
Mol Ther. 2020 Jul 8; 28(7): 1731–1740. Published online 2020 Mar 19. doi: 10.1016/j.ymthe.2020.03.011
PMCID:
PMC7335717
AbstractArticlePDF–2.2M
9.
VEGF‐B signaling impairs endothelial glucose transcytosis by decreasing membrane cholesterol content
Christine Moessinger, Ingrid Nilsson, Lars Muhl, Manuel Zeitelhofer, Benjamin Heller Sahlgren, Josefin Skogsberg, Ulf Eriksson
EMBO Rep. 2020 Jul 3; 21(7): e49343. Published online 2020 May 24. doi: 10.15252/embr.201949343
PMCID:
PMC7332976
AbstractArticlePDF–3.0M
10.
VEGF-B ablation in pancreatic β-cells upregulates insulin expression without affecting glucose homeostasis or islet lipid uptake
Frank Chenfei Ning, Nina Jensen, Jiarui Mi, William Lindström, Mirela Balan, Lars Muhl, Ulf Eriksson, Ingrid Nilsson, Daniel Nyqvist
Sci Rep. 2020; 10: 923. Published online 2020 Jan 22. doi: 10.1038/s41598-020-57599-2
PMCID:
PMC6976647
AbstractArticlePDF–6.5M
11.
CircAnks1a in the spinal cord regulates hypersensitivity in a rodent model of neuropathic pain
Su-Bo Zhang, Su-Yan Lin, Meng Liu, Cui-Cui Liu, Huan-Huan Ding, Yang Sun, Chao Ma, Rui-Xian Guo, You-You Lv, Shao-Ling Wu, Ting Xu, Wen-Jun Xin
Nat Commun. 2019; 10: 4119. Published online 2019 Sep 11. doi: 10.1038/s41467-019-12049-0
PMCID:
PMC6739334
AbstractArticlePDF–2.9M
12.
Novel Role for Vascular Endothelial Growth Factor (VEGF) Receptor-1 and Its Ligand VEGF-B in Motor Neuron Degeneration
Koen Poesen, Diether Lambrechts, Philip Van Damme, Joke Dhondt, Florian Bender, Nicolas Frank, Elke Bogaert, Bart Claes, Line Heylen, An Verheyen, Katrien Raes, Marc Tjwa, Ulf Eriksson, Masabumi Shibuya, Rony Nuydens, Ludo Van Den Bosch, Theo Meert, Rudi D'Hooge, Michael Sendtner, Wim Robberecht, Peter Carmeliet
J Neurosci. 2008 Oct 15; 28(42): 10451–10459. doi: 10.1523/JNEUROSCI.1092-08.2008
Correction in:
J Neurosci. 2008 Dec 17; 28(51): np.
PMCID:
PMC6671326
AbstractArticlePDF–343K
13.
Secondary Placental Defects in Cxadr Mutant Mice
Jennifer E. Outhwaite, Jatin Patel, David G. Simmons
Front Physiol. 2019; 10: 622. Published online 2019 May 29. doi: 10.3389/fphys.2019.00622
PMCID:
PMC6628872
AbstractArticlePDF–5.9M
14.
Developmental origins for semilunar valve stenosis identified in mice harboring congenital heart disease-associated GATA4 mutation
Stephanie LaHaye, Uddalak Majumdar, Jun Yasuhara, Sara N. Koenig, Adrianna Matos-Nieves, Rahul Kumar, Vidu Garg
Dis Model Mech. 2019 Jun 1; 12(6): dmm036764. Published online 2019 Jun 24. doi: 10.1242/dmm.036764
PMCID:
PMC6602309
AbstractArticle
15.
VEGF-B is a potent antioxidant
Pachiappan Arjunan, Xianchai Lin, Zhongshu Tang, Yuxiang Du, Anil Kumar, Lixian Liu, Xiangke Yin, Lijuan Huang, Wei Chen, Qishan Chen, Zhimin Ye, Shasha Wang, Haiqing Kuang, Linbin Zhou, Kai Xu, Xue Chen, Haitao Zeng, Weisi Lu, Yihai Cao, Yizhi Liu, Chen Zhao, Xuri Li
Proc Natl Acad Sci U S A. 2018 Oct 9; 115(41): 10351–10356. Published online 2018 Sep 24. doi: 10.1073/pnas.1801379115
PMCID:
PMC6187152
AbstractArticlePDF–1.9M
16.
Dynamic Expression of Genes Involved in Proteoglycan/Glycosaminoglycan Metabolism during Skin Development
P. J. E. Uijtdewilligen, E. M. Versteeg, E. M. A. van de Westerlo, J. van der Vlag, W. F. Daamen, T. H. van Kuppevelt
Biomed Res Int. 2018; 2018: 9873471. Published online 2018 Aug 29. doi: 10.1155/2018/9873471
PMCID:
PMC6136507
AbstractArticlePDF–838K
17.
VEGFB/VEGFR1-Induced Expansion of Adipose Vasculature Counteracts Obesity and Related Metabolic Complications
Marius R. Robciuc, Riikka Kivelä, Ian M. Williams, Jan Freark de Boer, Theo H. van Dijk, Harri Elamaa, Feven Tigistu-Sahle, Dmitry Molotkov, Veli-Matti Leppänen, Reijo Käkelä, Lauri Eklund, David H. Wasserman, Albert K. Groen, Kari Alitalo
Cell Metab. Author manuscript; available in PMC 2018 Apr 13.
Published in final edited form as: Cell Metab. 2016 Apr 12; 23(4): 712–724. doi: 10.1016/j.cmet.2016.03.004
PMCID:
PMC5898626
AbstractArticlePDF–1.3M
18.
ARID3A is required for mammalian placenta development
Catherine Rhee, Melissa Edwards, Christine Dang, June Harris, Mark Brown, Jonghwan Kim, Haley O Tucker
Dev Biol. Author manuscript; available in PMC 2017 Aug 2.
Published in final edited form as: Dev Biol. 2017 Feb 15; 422(2): 83–91. Published online 2016 Dec 11. doi: 10.1016/j.ydbio.2016.12.003
PMCID:
PMC5540318
AbstractArticlePDF–2.0M
19.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
20.
VEGF-B promotes recovery of corneal innervations and trophic functions in diabetic mice
Guohu Di, Xiaowen Zhao, Xia Qi, Songmei Zhang, Lu Feng, Weiyun Shi, Qingjun Zhou
Sci Rep. 2017; 7: 40582. Published online 2017 Jan 16. doi: 10.1038/srep40582
PMCID:
PMC5238415
AbstractArticlePDF–2.6M

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