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Select item 109164191.

NRF1 mitigates motor dysfunction and dopamine neuron degeneration in mice with Parkinson's disease by promoting GLRX m⁶A methylation through upregulation of METTL3 transcription

Xin Gong, Mengyi Huang, Lei Chen

CNS Neurosci Ther. 2024 Mar; 30(3): e14441. Published online 2023 Sep 22. doi: 10.1111/cns.14441

PMCID:: PMC10916419

Abstract Article PDF–17M

Select item 105118082.

Single-nucleus RNA-sequencing reveals NRF1/NFE2L1 as a key factor determining the thermogenesis and cellular heterogeneity and dynamics of brown adipose tissues in mice

Wei Shen, Suping Ren, Yongyong Hou, Zhuo Zuo, Shengnan Liu, Zhiyuan Liu, Jingqi Fu, Huihui Wang, Bei Yang, Rui Zhao, Yanyan Chen, Masayuki Yamamoto, Yuanyuan Xu, Qiang Zhang, Jingbo Pi

Redox Biol. 2023 Nov; 67: 102879. Published online 2023 Sep 11. doi: 10.1016/j.redox.2023.102879

PMCID:: PMC10511808

Abstract Article PDF–15M

Select item 104258783.

NRF1‐mediated mitochondrial biogenesis antagonizes innate antiviral immunity

Tian Zhao, Jiaojiao Zhang, Hong Lei, Yuanyuan Meng, Hongcheng Cheng, Yanping Zhao, Guangfeng Geng, Chenglong Mu, Linbo Chen, Qiangqiang Liu, Qian Luo, Chuanmei Zhang, Yijia Long, Jingyi Su, Yinhao Wang, Zhuoya Li, Jiaxing Sun, Guo Chen, Yanjun Li, Xudong Liao, Yingli Shang, Gang Hu, Quan Chen, Yushan Zhu

EMBO J. 2023 Aug; 42(16): e113258. Published online 2023 Jul 6. doi: 10.15252/embj.2022113258

PMCID:: PMC10425878

Abstract Article PDF–5.3M

Select item 99867424.

Hacd2 deficiency in mice leads to an early and lethal mitochondrial disease

Nahed Khadhraoui, Alexandre Prola, Aymeline Vandestienne, Jordan Blondelle, Laurent Guillaud, Guillaume Courtin, Maxime Bodak, Bastien Prost, Hélène Huet, Mélody Wintrebert, Christine Péchoux, Audrey Solgadi, Frédéric Relaix, Laurent Tiret, Fanny Pilot-Storck

Mol Metab. 2023 Mar; 69: 101677. Published online 2023 Jan 21. doi: 10.1016/j.molmet.2023.101677

PMCID:: PMC9986742

Abstract Article PDF–3.1M

Select item 94869285.

NRF1-mediated microglial activation triggers high-altitude cerebral edema

Xueting Wang, Guijuan Chen, Baolan Wan, Zhangji Dong, Yan Xue, Qianqian Luo, Dan Wang, Yapeng Lu, Li Zhu

J Mol Cell Biol. 2022 May; 14(5): mjac036. Published online 2022 Jun 15. doi: 10.1093/jmcb/mjac036

PMCID:: PMC9486928

Abstract Article PDF–3.8M

Select item 93277376.

Placental structure, function, and mitochondrial phenotype relate to fetal size in each fetal sex in mice

Esteban Salazar-Petres, Daniela Pereira-Carvalho, Jorge Lopez-Tello, Amanda Nancy Sferruzzi-Perri

Biol Reprod. 2022 Jun; 106(6): 1292–1311. Published online 2022 Mar 16. doi: 10.1093/biolre/ioac056

PMCID:: PMC9327737

Abstract Article PDF–3.0M

Select item 93212227.

Differential Susceptibility of Retinal Neurons to the Loss of Mitochondrial Biogenesis Factor Nrf1

Takae Kiyama, Ching-Kang Chen, Annie Zhang, Chai-An Mao

Cells. 2022 Jul; 11(14): 2203. Published online 2022 Jul 14. doi: 10.3390/cells11142203

PMCID:: PMC9321222

Abstract Article PDF–28M

Select item 86047848.

NRF1 Association with AUTS2-Polycomb Mediates Specific Gene Activation in the Brain

Sanxiong Liu, Kimberly A. Aldinger, Chi Vicky Cheng, Takae Kiyama, Mitali Dave, Hanna K. McNamara, Wukui Zhao, James M. Stafford, Nicolas Descostes, Pedro Lee, Stefano G. Caraffi, Ivan Ivanovski, Edoardo Errichiello, Christiane Zweier, Orsetta Zuffardi, Michael Schneider, Antigone S. Papavasiliou, M. Scott Perry, Jennifer Humberson, Megan T. Cho, Astrid Weber, Andrew Swale, Tudor C. Badea, Chai-An Mao, Livia Garavelli, William B. Dobyns, Danny Reinberg

Mol Cell. Author manuscript; available in PMC 2022 Nov 18.

Published in final edited form as: Mol Cell. 2021 Nov 18; 81(22): 4663–4676.e8. Published online 2021 Oct 11. doi: 10.1016/j.molcel.2021.09.020

Correction in:: Mol Cell. 2021 Nov 18; 81(22): 4757.

PMCID:: PMC8604784

Abstract Article PDF–2.8M

Select item 80962309.

Myod1 and GR coordinate myofiber-specific transcriptional enhancers

Daniela Rovito, Anna-Isavella Rerra, Vanessa Ueberschlag-Pitiot, Shilpy Joshi, Nezih Karasu, Vanessa Dacleu-Siewe, Khalil Ben Rayana, Kamar Ghaibour, Maxime Parisotto, Arnaud Ferry, Scott A Jelinsky, Gilles Laverny, Bruno P Klaholz, Tom Sexton, Isabelle M L Billas, Delphine Duteil, Daniel Metzger

Nucleic Acids Res. 2021 May 7; 49(8): 4472–4492. Published online 2021 Apr 9. doi: 10.1093/nar/gkab226

PMCID:: PMC8096230

Abstract Article PDF–5.9M

Select item 780145310.

The histone H3-lysine 4-methyltransferase Mll4 regulates the development of growth hormone-releasing hormone-producing neurons in the mouse hypothalamus

Christian Huisman, Young A. Kim, Shin Jeon, Bongjin Shin, Jeonghoon Choi, Su Jeong Lim, Sung Min Youn, Younjung Park, Medha K. C., Sangsoo Kim, Soo-Kyung Lee, Seunghee Lee, Jae W. Lee

Nat Commun. 2021; 12: 256. Published online 2021 Jan 11. doi: 10.1038/s41467-020-20511-7

PMCID:: PMC7801453

Abstract Article PDF–5.6M

Select item 774418611.

Synergism and Antagonism of Two Distinct, but Confused, Nrf1 Factors in Integral Regulation of the Nuclear-to-Mitochondrial Respiratory and Antioxidant Transcription Networks

Shuwei Zhang, Yangxu Deng, Yuancai Xiang, Shaofan Hu, Lu Qiu, Yiguo Zhang

Oxid Med Cell Longev. 2020; 2020: 5097109. Published online 2020 Nov 16. doi: 10.1155/2020/5097109

PMCID:: PMC7744186

Abstract Article PDF–6.1M

Select item 727242412.

SIRT1 accelerates the progression of activity-based anorexia

Timothy M. Robinette, Justin W. Nicholatos, Adam B. Francisco, Kayla E. Brooks, Rachel Y. Diao, Sandro Sorbi, Valdo Ricca, Benedetta Nacmias, Miguel A. Brieño-Enríquez, Sergiy Libert

Nat Commun. 2020; 11: 2814. Published online 2020 Jun 4. doi: 10.1038/s41467-020-16348-9

PMCID:: PMC7272424

Abstract Article PDF–1.2M

Select item 722702813.

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss

Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs

Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931

PMCID:: PMC7227028

Abstract Article PDF–5.4M

Select item 671944114.

CDK2 regulates the NRF1/Ehmt1 axis during meiotic prophase I

Nathan Palmer, S. Zakiah A. Talib, Chandrahas Koumar Ratnacaram, Diana Low, Xavier Bisteau, Joanna Hui Si Lee, Elisabeth Pfeiffenberger, Heike Wollmann, Joel Heng Loong Tan, Sheena Wee, Radoslaw Sobota, Jayantha Gunaratne, Daniel M. Messerschmidt, Ernesto Guccione, Philipp Kaldis

J Cell Biol. 2019 Sep 2; 218(9): 2896–2918. Published online 2019 Jul 26. doi: 10.1083/jcb.201903125

PMCID:: PMC6719441

Abstract Article PDF–3.7M

Select item 644521715.

TCF11/Nrf1-Mediated Induction of Proteasome Expression Prevents Cytotoxicity by Rotenone

Franziska Sotzny, Eileen Schormann, Ina Kühlewindt, Annett Koch, Anja Brehm, Raphaela Goldbach-Mansky, Kate E. Gilling, Elke Krüger

Antioxid Redox Signal. 2016 Dec 1; 25(16): 870–885. Published online 2016 Dec 1. doi: 10.1089/ars.2015.6539

PMCID:: PMC6445217

Abstract Article PDF–956K

Select item 640056016.

ATM is activated by ATP depletion and modulates mitochondrial function through NRF1

Hei-Man Chow, Aifang Cheng, Xuan Song, Mavis R. Swerdel, Ronald P. Hart, Karl Herrup

J Cell Biol. 2019 Mar 4; 218(3): 909–928. doi: 10.1083/jcb.201806197

PMCID:: PMC6400560

Abstract Article PDF–4.5M

Select item 621436217.

A spontaneous mouse deletion in Mctp1 uncovers a long-range cis-regulatory region crucial for NR2F1 function during inner ear development

Basile Tarchini, Chantal Longo-Guess, Cong Tian, Abigail L.D. Tadenev, Nicholas Devanney, Kenneth R. Johnson

Dev Biol. Author manuscript; available in PMC 2019 Nov 15.

Published in final edited form as: Dev Biol. 2018 Nov 15; 443(2): 153–164. Published online 2018 Sep 11. doi: 10.1016/j.ydbio.2018.09.011

PMCID:: PMC6214362

Abstract Article PDF–1.9M

Select item 621309318.

Nrf1D Is the First Candidate Secretory Transcription Factor in the Blood Plasma, Its Precursor Existing as a Unique Redox-Sensitive Transmembrane CNC-bZIP Protein in Hemopoietic and Somatic Tissues

Jianxin Yuan, Hongxia Wang, Yuancai Xiang, Shaofan Hu, Shaojun Li, Meng Wang, Lu Qiu, Yiguo Zhang

Int J Mol Sci. 2018 Oct; 19(10): 2940. Published online 2018 Sep 27. doi: 10.3390/ijms19102940

PMCID:: PMC6213093

Abstract Article PDF–6.6M

Select item 619212119.

Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis

Takae Kiyama, Ching-Kang Chen, Steven W Wang, Ping Pan, Zhenlin Ju, Jing Wang, Shinako Takada, William H Klein, Chai-An Mao

Mol Neurodegener. 2018; 13: 56. Published online 2018 Oct 17. doi: 10.1186/s13024-018-0287-z

PMCID:: PMC6192121

Abstract Article PDF–12M

Select item 606247020.

A Negative Feedback Loop Between microRNA-378 and Nrf1 Promotes the Development of Hepatosteatosis in Mice Treated with a High Fat Diet

Tianpeng Zhang, Xiaoling Zhao, Clifford J. Steer, Guiqin Yan, Guisheng Song

Metabolism. Author manuscript; available in PMC 2019 Aug 1.

Published in final edited form as: Metabolism. 2018 Aug; 85: 183–191. Published online 2018 Apr 3. doi: 10.1016/j.metabol.2018.03.023

PMCID:: PMC6062470

Abstract Article PDF–2.2M

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