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Items: 1 to 20 of 27

1.
An integrated model for Gpr124 function in Wnt7a/b signaling among vertebrates
Michelle America, Naguissa Bostaille, Marie Eubelen, Maud Martin, Didier Y.R. Stainier, Benoit Vanhollebeke
Cell Rep. 2022 May 31; 39(9): 110902. Published online 2022 May 31. doi: 10.1016/j.celrep.2022.110902
PMCID:
PMC9171404
AbstractArticle
2.
The WNT7A/WNT7B/GPR124/RECK signaling module plays an essential role in mammalian limb development
Yanshu Wang, Arjun Venkatesh, Jiajia Xu, Mingxin Xu, John Williams, Philip M. Smallwood, Aaron James, Jeremy Nathans
Development. 2022 May 1; 149(9): dev200340. Published online 2022 May 12. doi: 10.1242/dev.200340
PMCID:
PMC9148564
AbstractArticle
3.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
4.
Tissue factor pathway inhibitor is required for cerebrovascular development in mice
Susan A. Maroney, Randal J. Westrick, Audrey C. Cleuren, Nicholas D. Martinez, Amy E. Siebert, Mark Zogg, David Ginsburg, Hartmut Weiler, Alan E. Mast
Blood. 2021 Jan 14; 137(2): 258–268. Prepublished online 2020 Jul 31. doi: 10.1182/blood.2020006054
PMCID:
PMC7820871
AbstractArticle
5.
A RECK-WNT7 Receptor-Ligand Interaction Enables Isoform-Specific Regulation of Wnt Bioavailability
Mario Vallon, Kanako Yuki, Thi D. Nguyen, Junlei Chang, Jenny Yuan, Dirk Siepe, Yi Miao, Markus Essler, Makoto Noda, K. Christopher Garcia, Calvin J. Kuo
Cell Rep. Author manuscript; available in PMC 2019 Jan 18.
Published in final edited form as: Cell Rep. 2018 Oct 9; 25(2): 339–349.e9. doi: 10.1016/j.celrep.2018.09.045
PMCID:
PMC6338448
AbstractArticlePDF–1.5M
6.
Interplay of the Norrin and Wnt7a/Wnt7b signaling systems in blood–brain barrier and blood–retina barrier development and maintenance
Yanshu Wang, Chris Cho, John Williams, Philip M. Smallwood, Chi Zhang, Harald J. Junge, Jeremy Nathans
Proc Natl Acad Sci U S A. 2018 Dec 11; 115(50): E11827–E11836. Published online 2018 Nov 26. doi: 10.1073/pnas.1813217115
Correction in:
Proc Natl Acad Sci U S A. 2019 Feb 26; 116(9): 3934.
PMCID:
PMC6294914
AbstractArticlePDF–3.6M
7.
Reck and Gpr124 are Essential Receptor Cofactors for Wnt7a/Wnt7b-Specific Signaling in Mammalian CNS Angiogenesis and Blood-Brain Barrier Regulation
Chris Cho, Philip M. Smallwood, Jeremy Nathans
Neuron. Author manuscript; available in PMC 2018 Aug 30.
Published in final edited form as: Neuron. 2017 Aug 30; 95(5): 1056–1073.e5. Published online 2017 Aug 10. doi: 10.1016/j.neuron.2017.07.031
Correction in:
Neuron. 2017 Aug 30; 95(5): 1221–1225.
PMCID:
PMC5586543
AbstractArticlePDF–4.6M
8.
Gpr124 is essential for blood–brain barrier integrity in central nervous system disease
Junlei Chang, Michael R Mancuso, Carolina Maier, Xibin Liang, Kanako Yuki, Lu Yang, Jeffrey W Kwong, Jing Wang, Varsha Rao, Mario Vallon, Cynthia Kosinski, J J Hailing Zhang, Amanda T Mah, Lijun Xu, Le Li, Sharareh Gholamin, Teresa F Reyes, Rui Li, Frank Kuhnert, Xiaoyuan Han, Jenny Yuan, Shin-Heng Chiou, Ari D Brettman, Lauren Daly, David C Corney, Samuel H Cheshier, Linda D Shortliffe, Xiwei Wu, Michael Snyder, Pak Chan, Rona G Giffard, Howard Y Chang, Katrin Andreasson, Calvin J Kuo
Nat Med. Author manuscript; available in PMC 2017 Aug 17.
Published in final edited form as: Nat Med. 2017 Apr; 23(4): 450–460. Published online 2017 Mar 13. doi: 10.1038/nm.4309
PMCID:
PMC5559385
AbstractArticlePDF–2.3M
9.
Oligodendrocyte precursors migrate along vasculature in the developing nervous system
Hui-Hsin Tsai, Jianqin Niu, Roeben Munji, Dimitrios Davalos, Junlei Chang, Haijing Zhang, An-Chi Tien, Calvin J. Kuo, Jonah R. Chan, Richard Daneman, Stephen P. J. Fancy
Science. Author manuscript; available in PMC 2017 Jun 15.
Published in final edited form as: Science. 2016 Jan 22; 351(6271): 379–384. doi: 10.1126/science.aad3839
PMCID:
PMC5472053
AbstractArticlePDF–2.2M
10.
Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis
Christian Lange, Miguel Turrero Garcia, Ilaria Decimo, Francesco Bifari, Guy Eelen, Annelies Quaegebeur, Ruben Boon, Hui Zhao, Bram Boeckx, Junlei Chang, Christine Wu, Ferdinand Le Noble, Diether Lambrechts, Mieke Dewerchin, Calvin J Kuo, Wieland B Huttner, Peter Carmeliet
EMBO J. 2016 May 2; 35(9): 924–941. Published online 2016 Feb 8. doi: 10.15252/embj.201592372
PMCID:
PMC5207321
AbstractArticlePDF–4.6M
11.
Early molecular events during retinoic acid induced differentiation of neuromesodermal progenitors
Thomas J. Cunningham, Alexandre Colas, Gregg Duester
Biol Open. 2016 Dec 15; 5(12): 1821–1833. Published online 2016 Oct 28. doi: 10.1242/bio.020891
PMCID:
PMC5200905
AbstractArticlePDF–3.0M
12.
International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein–Coupled Receptors
Jörg Hamann, Gabriela Aust, Demet Araç, Felix B. Engel, Caroline Formstone, Robert Fredriksson, Randy A. Hall, Breanne L. Harty, Christiane Kirchhoff, Barbara Knapp, Arunkumar Krishnan, Ines Liebscher, Hsi-Hsien Lin, David C. Martinelli, Kelly R. Monk, Miriam C. Peeters, Xianhua Piao, Simone Prömel, Torsten Schöneberg, Thue W. Schwartz, Kathleen Singer, Martin Stacey, Yuri A. Ushkaryov, Mario Vallon, Uwe Wolfrum, Mathew W. Wright, Lei Xu, Tobias Langenhan, Helgi B. Schiöth
Pharmacol Rev. 2015 Apr; 67(2): 338–367. Published online 2015 Apr. doi: 10.1124/pr.114.009647
PMCID:
PMC4394687
AbstractArticlePDF–3.0M
13.
Expression of the Immunoglobulin Superfamily Cell Adhesion Molecules in the Developing Spinal Cord and Dorsal Root Ganglion
Zirong Gu, Fumiyasu Imai, In Jung Kim, Hiroko Fujita, Kei ichi Katayama, Kensaku Mori, Yoshihiro Yoshihara, Yutaka Yoshida
PLoS One. 2015; 10(3): e0121550. Published online 2015 Mar 31. doi: 10.1371/journal.pone.0121550
PMCID:
PMC4380438
AbstractArticlePDF–36M
14.
GPR124 Functions as a WNT7-Specific Co-Activator of Canonical β-Catenin Signaling
Ekaterina Posokhova, Animesh Shukla, Steven Seaman, Suresh Volate, Mary Beth Hilton, Bofan Wu, Holly Morris, Deborah A. Swing, Ming Zhou, Enrique Zudaire, Jeffrey S. Rubin, Brad St. Croix
Cell Rep. Author manuscript; available in PMC 2016 Jan 13.
Published in final edited form as: Cell Rep. 2015 Jan 13; 10(2): 123–130. Published online 2014 Dec 31. doi: 10.1016/j.celrep.2014.12.020
PMCID:
PMC4331012
AbstractArticlePDF–1.9M
15.
Gpr124 controls CNS angiogenesis and blood-brain barrier integrity by promoting ligand-specific canonical Wnt signaling
Yulian Zhou, Jeremy Nathans
Dev Cell. Author manuscript; available in PMC 2015 Oct 27.
Published in final edited form as: Dev Cell. 2014 Oct 27; 31(2): 248–256. Published online 2014 Oct 16. doi: 10.1016/j.devcel.2014.08.018
PMCID:
PMC4223636
AbstractArticlePDF–2.8M
16.
Conditionals by inversion provide a universal method for the generation of conditional alleles
Aris N. Economides, David Frendewey, Peter Yang, Melissa G. Dominguez, Anthony T. Dore, Ivan B. Lobov, Trikaldarshi Persaud, Jose Rojas, Joyce McClain, Peter Lengyel, Gustavo Droguett, Rostislav Chernomorsky, Sean Stevens, Wojtek Auerbach, Thomas M. DeChiara, William Pouyemirou, Joseph M. Cruz, Jr., Kieran Feeley, Ian A. Mellis, Jason Yasenchack, Sarah J. Hatsell, LiQin Xie, Esther Latres, Lily Huang, Yuhong Zhang, Evangelos Pefanis, Dimitris Skokos, Ron A. Deckelbaum, Susan D. Croll, Samuel Davis, David M. Valenzuela, Nicholas W. Gale, Andrew J. Murphy, George D. Yancopoulos
Proc Natl Acad Sci U S A. 2013 Aug 20; 110(34): E3179–E3188. Published online 2013 Aug 5. doi: 10.1073/pnas.1217812110
PMCID:
PMC3752204
AbstractArticlePDF–1.8M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124
Frank Kuhnert, Michael R. Mancuso, Amir Shamloo, Hsiao-Ting Wang, Vir Choksi, Mareike Florek, Hua Su, Marcus Fruttiger, William L. Young, Sarah C. Heilshorn, Calvin J. Kuo
Science. Author manuscript; available in PMC 2011 May 23.
Published in final edited form as: Science. 2010 Nov 12; 330(6006): 985–989. doi: 10.1126/science.1196554
PMCID:
PMC3099479
AbstractArticlePDF–2.9M
19.
GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood–brain barrier
Mike Cullen, Mohammed K. Elzarrad, Steven Seaman, Enrique Zudaire, Janine Stevens, Mi Young Yang, Xiujie Li, Amit Chaudhary, Lihong Xu, Mary Beth Hilton, Daniel Logsdon, Emily Hsiao, Erica V. Stein, Frank Cuttitta, Diana C. Haines, Kunio Nagashima, Lino Tessarollo, Brad St. Croix
Proc Natl Acad Sci U S A. 2011 Apr 5; 108(14): 5759–5764. Published online 2011 Mar 18. doi: 10.1073/pnas.1017192108
PMCID:
PMC3078373
AbstractArticlePDF–1.1M
20.
Angiogenic sprouting into neural tissue requires Gpr124, an orphan G protein-coupled receptor
Keith D. Anderson, Li Pan, Xiao-man Yang, Virginia C. Hughes, Johnathon R. Walls, Melissa G. Dominguez, Mary V. Simmons, Patricia Burfeind, Yingzi Xue, Yi Wei, Lynn E. Macdonald, Gavin Thurston, Christopher Daly, Hsin Chieh Lin, Aris N. Economides, David M. Valenzuela, Andrew J. Murphy, George D. Yancopoulos, Nicholas W. Gale
Proc Natl Acad Sci U S A. 2011 Feb 15; 108(7): 2807–2812. Published online 2011 Jan 31. doi: 10.1073/pnas.1019761108
PMCID:
PMC3041062
AbstractArticlePDF–1.2M

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