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Select item 107924251.

Resistin stimulates PC-3 prostate cancer cell growth through stimulation of SOCS3 and SOCS5 genes

Chi-Wei Liu, Hsuan-Yu Peng, An-Ci Siao, Yi-Wei Tsuei, Yen-Yue Lin, Shine-Gwo Shiah, Li-Jane Shih, Chien-Chih Yeh, Shih-Wei Lee, Yung-Hsi Kao

Exp Biol Med (Maywood) 2023 Oct; 248(20): 1695–1707. Published online 2023 Aug 30. doi: 10.1177/15353702231191206

PMCID:: PMC10792425

Abstract Article PDF–3.2M

Select item 105688882.

Sequential inspiratory muscle exercise-noninvasive positive pressure ventilation alleviates oxidative stress in COPD by mediating SOCS5/JAK2/STAT3 pathway

Yirou Lei, Jiaying He, Fang Hu, Hao Zhu, Jing Gu, Lijuan Tang, Man Luo

BMC Pulm Med. 2023; 23: 385. Published online 2023 Oct 12. doi: 10.1186/s12890-023-02656-5

PMCID:: PMC10568888

Abstract Article PDF–3.1M

Select item 93421423.

SOCS5 contributes to temozolomide resistance in glioblastoma by regulating Bcl-2-mediated autophagy

Jie Yu, Lin Han, Feng Yang, Mingliang Zhao, Hong Zhou, Linwang Hu

Bioengineered. 2022; 13(6): 14125–14137. Published online 2022 Jun 22. doi: 10.1080/21655979.2022.2081463

PMCID:: PMC9342142

Abstract Article PDF–3.9M

Select item 88099634.

LncRNA DHRS4-AS1 ameliorates hepatocellular carcinoma by suppressing proliferation and promoting apoptosis via miR-522-3p/SOCS5 axis

Yongping Zhou, Kuan Li, Xuexia Zou, Zhiyuan Hua, Hao Wang, Wuyang Bian, Hong Wang, Fangming Chen, Tu Dai

Bioengineered. 2021; 12(2): 10862–10877. Published online 2021 Nov 29. doi: 10.1080/21655979.2021.1994719

PMCID:: PMC8809963

Abstract Article PDF–3.1M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 77388986.

H3K27 acetylation activated-COL6A1 promotes osteosarcoma lung metastasis by repressing STAT1 and activating pulmonary cancer-associated fibroblasts

Ying Zhang, Zhaoyong Liu, Xia Yang, Weiqing Lu, Yelong Chen, Youbin Lin, Jin Wang, Suxia Lin, Jing-Ping Yun

Theranostics. 2021; 11(3): 1473–1492. Published online 2021 Jan 1. doi: 10.7150/thno.51245

Correction in:: Theranostics. 2022; 12(10): 4604–4605.

PMCID:: PMC7738898

Abstract Article PDF–4.9M

Select item 75295537.

Long non‐coding RNA HCG11 sponging miR‐522‐3p inhibits the tumorigenesis of non‐small cell lung cancer by upregulating SOCS5

Gang Fan, Jin Jiao, Feng Shen, Qingxia Ren, Qing Wang, Fulu Chu

Thorac Cancer. 2020 Oct; 11(10): 2877–2886. Published online 2020 Aug 26. doi: 10.1111/1759-7714.13624

PMCID:: PMC7529553

Abstract Article PDF–3.5M

Select item 70501038.

AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair

Zhen Chen, Chao Wang, Antrix Jain, Mrinal Srivastava, Mengfan Tang, Huimin Zhang, Xu Feng, Litong Nie, Dan Su, Yun Xiong, Sung Yun Jung, Jun Qin, Junjie Chen

Mol Cell Proteomics. 2020 Mar; 19(3): 467–477. Published online 2020 Jan 3. doi: 10.1074/mcp.RA119.001794

PMCID:: PMC7050103

Abstract Article PDF–1.8M

Select item 69277549.

Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC

Hao Zeng, Johnny Castillo-Cabrera, Mika Manser, Bo Lu, Zinger Yang, Vaik Strande, Damien Begue, Raffaella Zamponi, Shumei Qiu, Frederic Sigoillot, Qiong Wang, Alicia Lindeman, John S Reece-Hoyes, Carsten Russ, Debora Bonenfant, Xiaomo Jiang, Youzhen Wang, Feng Cong

eLife. 2019; 8: e50223. Published online 2019 Nov 19. doi: 10.7554/eLife.50223

PMCID:: PMC6927754

Abstract Article PDF–5.1M

Select item 669095210.

SOCS5 inhibition induces autophagy to impair metastasis in hepatocellular carcinoma cells via the PI3K/Akt/mTOR pathway

Mao Zhang, Shihai Liu, Mei-Sze Chua, Haoran Li, Dingan Luo, Sheng Wang, Shun Zhang, Bing Han, Chuandong Sun

Cell Death Dis. 2019 Aug; 10(8): 612. Published online 2019 Aug 13. doi: 10.1038/s41419-019-1856-y

Correction in:: Cell Death Dis. 2019 Nov; 10(11): 799.

PMCID:: PMC6690952

Abstract Article PDF–7.3M

Select item 654993311.

Epigenetic silencing of SOCS5 potentiates JAK‐STAT signaling and progression of T‐cell acute lymphoblastic leukemia

Nitesh D. Sharma, Christian K. Nickl, Huining Kang, Wojciech Ornatowski, Roger Brown, Scott A. Ness, Mignon L. Loh, Charles G. Mullighan, Stuart S. Winter, Stephen P. Hunger, Judy L. Cannon, Ksenia Matlawska‐Wasowska

Cancer Sci. 2019 Jun; 110(6): 1931–1946. Published online 2019 May 3. doi: 10.1111/cas.14021

PMCID:: PMC6549933

Abstract Article PDF–3.0M

Select item 567858112.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 553161113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 535451914.

Suppressor of cytokine signaling (SOCS)5 ameliorates influenza infection via inhibition of EGFR signaling

Lukasz Kedzierski, Michelle D Tate, Alan C Hsu, Tatiana B Kolesnik, Edmond M Linossi, Laura Dagley, Zhaoguang Dong, Sarah Freeman, Giuseppe Infusini, Malcolm R Starkey, Nicola L Bird, Simon M Chatfield, Jeffrey J Babon, Nicholas Huntington, Gabrielle Belz, Andrew Webb, Peter AB Wark, Nicos A Nicola, Jianqing Xu, Katherine Kedzierska, Philip M Hansbro, Sandra E Nicholson

eLife. 2017; 6: e20444. Published online 2017 Feb 14. doi: 10.7554/eLife.20444

PMCID:: PMC5354519

Abstract Article PDF–3.9M

Select item 521679915.

Deregulation of SOCS5 suppresses dendritic cell function in chronic lymphocytic leukemia

Patricia A. Toniolo, Suhu Liu, Jennifer E. Yeh, Darwin Q. Ye, José Alexandre M. Barbuto, David A. Frank

Oncotarget. 2016 Jul 19; 7(29): 46301–46314. Published online 2016 Jun 15. doi: 10.18632/oncotarget.10093

PMCID:: PMC5216799

Abstract Article PDF–3.9M

Select item 408311016.

Enhanced Prediction of Src Homology 2 (SH2) Domain Binding Potentials Using a Fluorescence Polarization-derived c-Met, c-Kit, ErbB, and Androgen Receptor Interactome

Kin K. Leung, Ronald J. Hause, Jr., John L. Barkinge, Mark F. Ciaccio, Chih-Pin Chuu, Richard B. Jones

Mol Cell Proteomics. 2014 Jul; 13(7): 1705–1723. Published online 2014 Apr 12. doi: 10.1074/mcp.M113.034876

PMCID:: PMC4083110

Abstract Article PDF–6.6M

Select item 386025817.

Gene-alcohol interactions identify several novel blood pressure loci including a promising locus near SLC16A9

Jeannette Simino, Yun Ju Sung, Rezart Kume, Karen Schwander, D. C. Rao

Front Genet. 2013; 4: 277. Published online 2013 Dec 12. doi: 10.3389/fgene.2013.00277

PMCID:: PMC3860258

Abstract Article PDF–2.9M

Select item 374913618.

Suppressor of Cytokine Signaling (SOCS) 5 Utilises Distinct Domains for Regulation of JAK1 and Interaction with the Adaptor Protein Shc-1

Edmond M. Linossi, Indu R. Chandrashekaran, Tatiana B. Kolesnik, James M. Murphy, Andrew I. Webb, Tracy A. Willson, Lukasz Kedzierski, Alex N. Bullock, Jeffrey J. Babon, Raymond S. Norton, Nicos A. Nicola, Sandra E. Nicholson

PLoS One. 2013; 8(8): e70536. Published online 2013 Aug 21. doi: 10.1371/journal.pone.0070536

PMCID:: PMC3749136

Abstract Article PDF–3.3M

Select item 357913819.

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

James A Nathan, Hyoung Tae Kim, Lily Ting, Steven P Gygi, Alfred L Goldberg

EMBO J. 2013 Feb 20; 32(4): 552–565. Published online 2013 Jan 11. doi: 10.1038/emboj.2012.354

PMCID:: PMC3579138

Abstract Article PDF–1.5M

Select item 343378220.

Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway

Guanglei Zhuang, Xiumin Wu, Zhaoshi Jiang, Ian Kasman, Jenny Yao, Yinghui Guan, Jason Oeh, Zora Modrusan, Carlos Bais, Deepak Sampath, Napoleone Ferrara

EMBO J. 2012 Aug 29; 31(17): 3513–3523. Published online 2012 Jul 6. doi: 10.1038/emboj.2012.183

PMCID:: PMC3433782

Abstract Article PDF–888K

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