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Items: 1 to 20 of 41

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Cell type-specific role of CBX2 and its disordered region in spermatogenesis
Jongmin J. Kim, Emma R. Steinson, Mei Sheng Lau, Dirk G. de Rooij, David C. Page, Robert E. Kingston
Genes Dev. 2023 Jul 1; 37(13-14): 640–660. doi: 10.1101/gad.350393.122
PMCID:
PMC10499018
AbstractArticlePDF–9.9M
3.
Polycomb group protein CBX7 represses cardiomyocyte proliferation via modulation of the TARDBP/RBM38 axis
Kyu-Won Cho, Mark Andrade, Seongho Bae, Sangsung Kim, Jin Eyun Kim, Er Yearn Jang, Sangho Lee, Ahsan Husain, Roy L. Sutliff, John W. Calvert, Changwon Park, Young-sup Yoon
Circulation. Author manuscript; available in PMC 2024 Jun 13.
Published in final edited form as: Circulation. 2023 Jun 13; 147(24): 1823–1842. Published online 2023 May 9. doi: 10.1161/CIRCULATIONAHA.122.061131
PMCID:
PMC10330362
AbstractArticlePDF–1.6M
4.
Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis
Dahai Wang, Mayuri Tanaka-Yano, Eleanor Meader, Melissa A. Kinney, Vivian Morris, Edroaldo Lummertz da Rocha, Nan Liu, Tianxin Liu, Qian Zhu, Stuart H. Orkin, Trista E. North, George Q. Daley, R. Grant Rowe
Cell Rep. Author manuscript; available in PMC 2022 Apr 22.
Published in final edited form as: Cell Rep. 2022 Apr 5; 39(1): 110587. doi: 10.1016/j.celrep.2022.110587
PMCID:
PMC9029260
AbstractArticlePDF–3.1M
5.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
6.
TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation
Xiaochen Fan, V Pragathi Masamsetti, Jane QJ Sun, Kasper Engholm-Keller, Pierre Osteil, Joshua Studdert, Mark E Graham, Nicolas Fossat, Patrick PL Tam
eLife. 2021; 10: e62873. Published online 2021 Feb 8. doi: 10.7554/eLife.62873
PMCID:
PMC7968925
AbstractArticlePDF–4.0M
7.
CBX2 depletion inhibits the proliferation, invasion and migration of gastric cancer cells by inactivating the YAP/β-catenin pathway
Miaomiao Zeng, Bangxue Li, Lei Yang, Quanlin Guan
Mol Med Rep. 2021 Feb; 23(2): 137. Published online 2020 Dec 13. doi: 10.3892/mmr.2020.11776
PMCID:
PMC7751489
AbstractArticlePDF–939K
8.
Loss of CBX2 induces genome instability and senescence-associated chromosomal rearrangements
Claudia Baumann, Xiangyu Zhang, Rabindranath De La Fuente
J Cell Biol. 2020 Nov 2; 219(11): e201910149. Published online 2020 Sep 1. doi: 10.1083/jcb.201910149
PMCID:
PMC7594495
AbstractArticlePDF–6.7M
9.
Phase separation of Polycomb-repressive complex 1 is governed by a charged disordered region of CBX2
Aaron J. Plys, Christopher P. Davis, Jongmin Kim, Gizem Rizki, Madeline M. Keenen, Sharon K. Marr, Robert E. Kingston
Genes Dev. 2019 Jul 1; 33(13-14): 799–813. doi: 10.1101/gad.326488.119
PMCID:
PMC6601514
AbstractArticlePDF–11M
10.
CBX2 is required to stabilize the testis pathway by repressing Wnt signaling
S. Alexandra Garcia-Moreno, Yi-Tzu Lin, Christopher R. Futtner, Isabella M. Salamone, Blanche Capel, Danielle M. Maatouk
PLoS Genet. 2019 May; 15(5): e1007895. Published online 2019 May 22. doi: 10.1371/journal.pgen.1007895
PMCID:
PMC6548405
AbstractArticlePDF–3.7M
11.
Polycomb chromobox Cbx2 enhances antiviral innate immunity by promoting Jmjd3-mediated demethylation of H3K27 at the Ifnb promoter
Donghao Sun, Xuetao Cao, Chunmei Wang
Protein Cell. 2019 Apr; 10(4): 285–294. Published online 2018 Oct 24. doi: 10.1007/s13238-018-0581-0
PMCID:
PMC6418077
AbstractArticlePDF–1.2M
12.
Nuclear condensates of the Polycomb protein chromobox 2 (CBX2) assemble through phase separation
Roubina Tatavosian, Samantha Kent, Kyle Brown, Tingting Yao, Huy Nguyen Duc, Thao Ngoc Huynh, Chao Yu Zhen, Brian Ma, Haobin Wang, Xiaojun Ren
J Biol Chem. 2019 Feb 1; 294(5): 1451–1463. Published online 2018 Dec 4. doi: 10.1074/jbc.RA118.006620
PMCID:
PMC6364756
AbstractArticlePDF–2.2M
13.
The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1
Gina E. Elsen, Francesco Bedogni, Rebecca D. Hodge, Theo K. Bammler, James W. MacDonald, Susan Lindtner, John L. R. Rubenstein, Robert F. Hevner
Front Neurosci. 2018; 12: 571. Published online 2018 Aug 22. doi: 10.3389/fnins.2018.00571
PMCID:
PMC6113890
AbstractArticlePDF–4.8M
14.
Mutation of a nucleosome compaction region disrupts Polycomb-mediated axial patterning
Mei Sheng Lau, Matthew G. Schwartz, Sharmistha Kundu, Andrej J. Savol, Peggy I. Wang, Sharon K. Marr, Daniel J. Grau, Patrick Schorderet, Ruslan I. Sadreyev, Clifford J. Tabin, Robert E. Kingston
Science. Author manuscript; available in PMC 2018 Mar 10.
Published in final edited form as: Science. 2017 Mar 10; 355(6329): 1081–1084. Published online 2017 Mar 9. doi: 10.1126/science.aah5403
PMCID:
PMC5503153
AbstractArticlePDF–1.1M
15.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
16.
Cbx2 stably associates with mitotic chromosomes via a PRC2- or PRC1-independent mechanism and is needed for recruiting PRC1 complex to mitotic chromosomes
Chao Yu Zhen, Huy Nguyen Duc, Marko Kokotovic, Christopher J. Phiel, Xiaojun Ren
Mol Biol Cell. 2014 Nov 15; 25(23): 3726–3739. doi: 10.1091/mbc.E14-06-1109
PMCID:
PMC4230780
AbstractArticlePDF–5.2M
17.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
18.
Heterochromatin protein 1 promotes self-renewal and triggers regenerative proliferation in adult stem cells
An Zeng, Yong-Qin Li, Chen Wang, Xiao-Shuai Han, Ge Li, Jian-Yong Wang, Dang-Sheng Li, Yong-Wen Qin, Yufang Shi, Gary Brewer, Qing Jing
J Cell Biol. 2013 Apr 29; 201(3): 409–425. doi: 10.1083/jcb.201207172
PMCID:
PMC3639387
AbstractArticlePDF–6.4M
19.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
20.
Compaction of chromatin by diverse Polycomb group proteins requires localized regions of high charge
Daniel J. Grau, Brad A. Chapman, Joe D. Garlick, Mark Borowsky, Nicole J. Francis, Robert E. Kingston
Genes Dev. 2011 Oct 15; 25(20): 2210–2221. doi: 10.1101/gad.17288211
PMCID:
PMC3205590
AbstractArticlePDF–1.7M

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