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Select item 84709391.

GDF6 Knockdown in a Family with Multiple Synostosis Syndrome and Speech Impairment

Raymond A. Clarke, Zhiming Fang, Dedee Murrell, Tabrez Sheriff, Valsamma Eapen

Genes (Basel) 2021 Sep; 12(9): 1354. Published online 2021 Aug 29. doi: 10.3390/genes12091354

PMCID:: PMC8470939

Abstract Article PDF–2.3M

Select item 84562032.

A Novel Human Long Noncoding RNA SCDAL Promotes Angiogenesis through SNF5‐Mediated GDF6 Expression

Rongrong Wu, Wangxing Hu, Huan Chen, Yingchao Wang, Qingju Li, Changchen Xiao, Lin Fan, Zhiwei Zhong, Xiaoying Chen, Kaiqi Lv, Shuhan Zhong, Yanna Shi, Jinghai Chen, Wei Zhu, Jianyi Zhang, Xinyang Hu, Jian'an Wang

Adv Sci (Weinh) 2021 Sep; 8(18): 2004629. Published online 2021 Jul 28. doi: 10.1002/advs.202004629

PMCID:: PMC8456203

Abstract Article PDF–12M

Select item 83934303.

siRNA Mediate RNA Interference Concordant with Early On-Target Transient Transcriptional Interference

Zhiming Fang, Zhongming Zhao, Valsamma Eapen, Raymond A. Clarke

Genes (Basel) 2021 Aug; 12(8): 1290. Published online 2021 Aug 23. doi: 10.3390/genes12081290

PMCID:: PMC8393430

Abstract Article PDF–2.5M

Select item 77848744.

Rare heterozygous GDF6 variants in patients with renal anomalies

Helge Martens, Imke Hennies, Maike Getwan, Anne Christians, Anna-Carina Weiss, Frank Brand, Ann Christin Gjerstad, Arne Christians, Zoran Gucev, Robert Geffers, Tomáš Seeman, Andreas Kispert, Velibor Tasic, Anna Bjerre, Soeren S. Lienkamp, Dieter Haffner, Ruthild G. Weber

Eur J Hum Genet. 2020 Dec; 28(12): 1681–1693. Published online 2020 Jul 31. doi: 10.1038/s41431-020-0678-9

PMCID:: PMC7784874

Abstract Article PDF–10M

Select item 76883435.

GDF6-CD99 Signaling Regulates Src and Ewing Sarcoma Growth

Fuchun Zhou, David J. Elzi, Panneerselvam Jayabal, Xiuye Ma, Yu-Chiao Chiu, Yidong Chen, Barron Blackman, Susan T. Weintraub, Peter J. Houghton, Yuzuru Shiio

Cell Rep. Author manuscript; available in PMC 2020 Nov 25.

Published in final edited form as: Cell Rep. 2020 Nov 3; 33(5): 108332. doi: 10.1016/j.celrep.2020.108332

PMCID:: PMC7688343

Abstract Article PDF–1.9M

Select item 75823666.

Regenerative Response of Degenerate Human Nucleus Pulposus Cells to GDF6 Stimulation

Tom Hodgkinson, Hamish T. J. Gilbert, Tej Pandya, Ashish D. Diwan, Judith A. Hoyland, Stephen M. Richardson

Int J Mol Sci. 2020 Oct; 21(19): 7143. Published online 2020 Sep 27. doi: 10.3390/ijms21197143

PMCID:: PMC7582366

Abstract Article PDF–2.2M

Select item 74100447.

Long-range cis-regulatory elements controlling GDF6 expression are essential for ear development

Guney Bademci, Clemer Abad, Filiz B. Cengiz, Serhat Seyhan, Armagan Incesulu, Shengru Guo, Suat Fitoz, Emine Ikbal Atli, Nicholas C. Gosstola, Selma Demir, Brett M. Colbert, Gozde Cosar Seyhan, Claire J. Sineni, Duygu Duman, Hakan Gurkan, Cynthia C. Morton, Derek M. Dykxhoorn, Katherina Walz, Mustafa Tekin

J Clin Invest. 2020 Aug 3; 130(8): 4213–4217. Published online 2020 Jun 29. doi: 10.1172/JCI136951

PMCID:: PMC7410044

Abstract Article PDF–4.0M

Select item 62993688.

The intracellular NADH level regulates atrophic nonunion pathogenesis through the CtBP2-p300-Runx2 transcriptional complex

Wentao Zhang, Ning Duan, Qian Zhang, Tao Song, Zhong Li, Xun Chen, Kunzheng Wang

Int J Biol Sci. 2018; 14(14): 2023–2036. Published online 2018 Nov 3. doi: 10.7150/ijbs.28302

PMCID:: PMC6299368

Abstract Article PDF–2.0M

Select item 57854479.

Growth Differentiation Factor 6 (GDF6) promotes vascular stability by restraining VEGF signaling

Shlomo Krispin, Amber N. Stratman, Chase H. Melick, Radu V. Stan, Matteo Malinverno, Jamie Gleklen, Daniel Castranova, Elisabetta Dejana, Brant M. Weinstein

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2018 Feb; 38(2): 353–362. Published online 2017 Dec 28. doi: 10.1161/ATVBAHA.117.309571

PMCID:: PMC5785447

Abstract Article PDF–2.3M

Select item 526816610.

A New Subtype of Multiple Synostoses Syndrome Is Caused by a Mutation in GDF6 That Decreases Its Sensitivity to Noggin and Enhances Its Potency as a BMP Signal

Jian Wang, Tingting Yu, Zhigang Wang, Satoshi Ohte, Ru-en Yao, Zhaojing Zheng, Juan Geng, Haiqing Cai, Yihua Ge, Yuchan Li, Yunlan Xu, Qinghua Zhang, James F Gusella, Qihua Fu, Steven Pregizer, Vicki Rosen, Yiping Shen

J Bone Miner Res. Author manuscript; available in PMC 2017 Jan 26.

Published in final edited form as: J Bone Miner Res. 2016 Apr; 31(4): 882–889. Published online 2015 Dec 28. doi: 10.1002/jbmr.2761

PMCID:: PMC5268166

Abstract Article PDF–762K

Select item 425168111.

Association of rs6982567 near GDF6 with neovascular age-related macular degeneration and polypoidal choroidal vasculopathy in a Han Chinese cohort

Yuying Ji, Xiongze Zhang, Kunfang Wu, Yu Su, Meng Li, Chengguo Zuo, Feng Wen

BMC Ophthalmol. 2014; 14: 140. Published online 2014 Nov 22. doi: 10.1186/1471-2415-14-140

PMCID:: PMC4251681

Abstract Article PDF–282K

Select item 358094112.

BMP12 and BMP13 gene transfer induce ligamentogenic differentiation in mesenchymal progenitor and anterior cruciate ligament cells

MEIKE HADDAD-WEBER, PATRICK PRAGER, MANUELA KUNZ, LOTHAR SEEFRIED, FRANZ JAKOB, MARTHA M. MURRAY, CHRISTOPHER H. EVANS, ULRICH NÖTH, ANDRE F. STEINERT

Cytotherapy. Author manuscript; available in PMC 2013 Feb 25.

Published in final edited form as: Cytotherapy. 2010 Jul; 12(4): 505–513. doi: 10.3109/14653241003709652

PMCID:: PMC3580941

Abstract Article PDF–1.5M

Select item 325686413.

High Temperature Requirement Factor A1 (HTRA1) Gene Regulates Angiogenesis through Transforming Growth Factor-β Family Member Growth Differentiation Factor 6

Li Zhang, Siok Lam Lim, Hongjun Du, Ming Zhang, Igor Kozak, Gregory Hannum, Xiaolei Wang, Hong Ouyang, Guy Hughes, Ling Zhao, Xuemei Zhu, Clara Lee, Zhiguang Su, Xinrong Zhou, Robert Shaw, Dongho Geum, Xinran Wei, Jin Zhu, Trey Ideker, Chio Oka, Ningli Wang, Zhenglin Yang, Peter X. Shaw, Kang Zhang

J Biol Chem. 2012 Jan 6; 287(2): 1520–1526. Published online 2011 Nov 2. doi: 10.1074/jbc.M111.275990

PMCID:: PMC3256864

Abstract Article PDF–1.3M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 315454215.

Divergent activities of osteogenic BMP2, and tenogenic BMP12 and BMP13 independent of receptor binding affinities

Stephen P Berasi, Usha Varadarajan, Joanne Archambault, Michael Cain, Tatyana A Souza, Abe Abouzeid, Jian Li, Christopher T Brown, Andrew J Dorner, Howard J Seeherman, Scott A Jelinsky

Growth Factors. 2011 Aug; 29(4): 128–139. Published online 2011 Jun 27. doi: 10.3109/08977194.2011.593178

PMCID:: PMC3154542

Abstract Article PDF–1.9M

Select item 296729716.

A large-scale candidate-gene association study of age at menarche and age at natural menopause

Chunyan He, Peter Kraft, Daniel I. Chasman, Julie E. Buring, Constance Chen, Susan E. Hankinson, Guillaume Paré, Stephen Chanock, Paul M. Ridker, David J. Hunter

Hum Genet. Author manuscript; available in PMC 2010 Nov 1.

Published in final edited form as: Hum Genet. 2010 Nov; 128(5): 515–527. Published online 2010 Aug 24. doi: 10.1007/s00439-010-0878-4