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Items: 1 to 20 of 73

1.
BRD9-SMAD2/3 Orchestrates Stemness and Tumorigenesis in Pancreatic Ductal Adenocarcinoma
Yuliang Feng, Liuyang Cai, Martin Pook, Feng Liu, Chao-Hui Chang, Mai Abdel Mouti, Reshma Nibhani, Stefania Militi, James Dunford, Martin Philpott, Yanbo Fan, Guo-Chang Fan, Qi Liu, Jun Qi, Cheng Wang, Wanzi Hong, Hannah Morgan, Mingyang Wang, Sakthivel Sadayappan, Anil G. Jegga, Udo Oppermann, Yigang Wang, Wei Huang, Lei Jiang, Siim Pauklin
Gastroenterology. Author manuscript; available in PMC 2024 Aug 7.
Published in final edited form as: Gastroenterology. 2024 Jan; 166(1): 139–154. Published online 2023 Sep 21. doi: 10.1053/j.gastro.2023.09.021
PMCID:
PMC11304550
AbstractArticlePDF–3.2M
2.
BRD9 regulates normal human hematopoietic stem cell function and lineage differentiation
Swati Garg, Wei Ni, Basudev Chowdhury, Ellen L. Weisberg, Martin Sattler, James D. Griffin
Cell Death Differ. 2024 Jul; 31(7): 868–880. Published online 2024 May 30. doi: 10.1038/s41418-024-01306-5
PMCID:
PMC11239944
AbstractArticlePDF–42M
3.
Interaction network of human early embryonic transcription factors
Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo
EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0
PMCID:
PMC10933267
AbstractArticlePDF–2.9M
4.
Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7
Joseph S. Baxter, Rachel Brough, Dragomir B. Krastev, Feifei Song, Sandhya Sridhar, Aditi Gulati, John Alexander, Theodoros I. Roumeliotis, Zuza Kozik, Jyoti S. Choudhary, Syed Haider, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord
Mol Oncol. 2024 Feb; 18(2): 369–385. Published online 2023 Oct 22. doi: 10.1002/1878-0261.13537
PMCID:
PMC10850818
AbstractArticlePDF–2.7M
5.
Pan‐cancer analyses of bromodomain containing 9 as a novel therapeutic target reveals its diagnostic, prognostic potential and biological mechanism in human tumours
Yu Chen, Zitong Gao, Isam Mohd‐Ibrahim, Hua Yang, Lang Wu, Yuanyuan Fu, Youping Deng
Clin Transl Med. 2024 Feb; 14(2): e1543. Published online 2024 Feb 1. doi: 10.1002/ctm2.1543
PMCID:
PMC10835192
AbstractArticlePDF–13M
6.
The ncBAF Complex Regulates Transcription in AML Through H3K27ac Sensing by BRD9
David C. Klein, Santana M. Lardo, Sarah J. Hainer
Cancer Res Commun. 2024 Jan; 4(1): 237–252. Published online 2024 Jan 30. doi: 10.1158/2767-9764.CRC-23-0382
PMCID:
PMC10831031
AbstractArticlePDF–17M
7.
Bromodomain-Containing Protein 9 Regulates Signaling Pathways and Reprograms the Epigenome in Immortalized Human Uterine Fibroid Cells
Qiwei Yang, Somayeh Vafaei, Ali Falahati, Azad Khosh, Maria Victoria Bariani, Mervat M. Omran, Tao Bai, Hiba Siblini, Mohamed Ali, Chuan He, Thomas G. Boyer, Ayman Al-Hendy
Int J Mol Sci. 2024 Jan; 25(2): 905. Published online 2024 Jan 11. doi: 10.3390/ijms25020905
PMCID:
PMC10815284
AbstractArticlePDF–5.0M
8.
BRD9-mediated control of the TGF-β/Activin/Nodal pathway regulates self-renewal and differentiation of human embryonic stem cells and progression of cancer cells
Xuepeng Wang, Chengcheng Song, Ying Ye, Yashi Gu, Xuemei Li, Peixin Chen, Dongliang Leng, Jing Xiao, Hao Wu, Sisi Xie, Weiwei Liu, Qi Zhao, Di Chen, Xi Chen, Qiang Wu, Guokai Chen, Wensheng Zhang
Nucleic Acids Res. 2023 Nov 27; 51(21): 11634–11651. Published online 2023 Oct 23. doi: 10.1093/nar/gkad907
PMCID:
PMC10681724
AbstractArticlePDF–1.8M
9.
Large‐scale phosphomimetic screening identifies phospho‐modulated motif‐based protein interactions
Johanna Kliche, Dimitriya Hristoforova Garvanska, Leandro Simonetti, Dilip Badgujar, Doreen Dobritzsch, Jakob Nilsson, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2023 Jul; 19(7): e11164. Published online 2023 May 23. doi: 10.15252/msb.202211164
PMCID:
PMC10333884
AbstractArticlePDF–5.0M
10.
BRD9 Degradation Disrupts Ribosome Biogenesis in Multiple Myeloma
Keiji Kurata, Mehmet K. Samur, Priscilla Liow, Kenneth Wen, Leona Yamamoto, Jiye Liu, Eugenio Morelli, Annamaria Gulla, Yu-Tzu Tai, Jun Qi, Teru Hideshima, Kenneth C. Anderson
Clin Cancer Res. 2023 May 1; 29(9): 1807–1821. Published online 2023 Feb 13. doi: 10.1158/1078-0432.CCR-22-3668
Correction in:
Clin Cancer Res. 2024 Sep 3; 30(17): 3956.
PMCID:
PMC10150249
AbstractArticlePDF–11M
11.
BRD9 is an essential regulator of glycolysis that creates an epigenetic vulnerability in colon adenocarcinoma
Qunshan Zhu, Xiang Gu, Wei Wei, Zheng Wu, Fengqin Gong, Xiaoqiang Dong
Cancer Med. 2023 Jan; 12(2): 1572–1587. Published online 2022 Jul 2. doi: 10.1002/cam4.4954
PMCID:
PMC9883419
AbstractArticlePDF–12M
12.
TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1
Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel
J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144
PMCID:
PMC9797988
AbstractArticlePDF–6.9M
13.
The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers
Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy
eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676
PMCID:
PMC9708086
AbstractArticlePDF–8.5M
14.
A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation
Yulemi Gonzalez Quesada, Luc DesGroseillers
Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588
PMCID:
PMC9569955
AbstractArticlePDF–2.1M
15.
The in vivo Interaction Landscape of Histones H3.1 and H3.3
Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins
Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411
PMCID:
PMC9540345
AbstractArticlePDF–3.9M
16.
Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1
Amelia K. Luciano, Ekaterina D. Korobkina, Scott P. Lyons, John A. Haley, Shelagh M. Fluharty, Su Myung Jung, Arminja N. Kettenbach, David A. Guertin
J Biol Chem. 2022 Oct; 298(10): 102379. Published online 2022 Aug 13. doi: 10.1016/j.jbc.2022.102379
PMCID:
PMC9513271
AbstractArticlePDF–2.7M
17.
Ultra-Rare BRD9 Loss-of-Function Variants Limit the Antiviral Action of Interferon
Nina K. Mair, Benjamin G. Hale
Sci Rep. 2022; 12: 15360. Published online 2022 Sep 13. doi: 10.1038/s41598-022-19648-w
PMCID:
PMC9468519
AbstractArticlePDF–3.1M
18.
The Functional Role and Regulatory Mechanism of Bromodomain-Containing Protein 9 in Human Uterine Leiomyosarcoma
Qiwei Yang, Maria Victoria Bariani, Ali Falahati, Azad Khosh, Ricardo R. Lastra, Hiba Siblini, Thomas G. Boyer, Ayman Al-Hendy
Cells. 2022 Jul; 11(14): 2160. Published online 2022 Jul 10. doi: 10.3390/cells11142160
PMCID:
PMC9323884
AbstractArticlePDF–3.4M
19.
BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma
Ellen Weisberg, Basudev Chowdhury, Chengcheng Meng, Abigail E. Case, Wei Ni, Swati Garg, Martin Sattler, Abdel Kareem Azab, Jennifer Sun, Barbara Muz, Dana Sanchez, Anthia Toure, Richard M. Stone, Ilene Galinsky, Eric Winer, Scott Gleim, Sofia Gkountela, Alexia Kedves, Edmund Harrington, Tinya Abrams, Thomas Zoller, Andrea Vaupel, Paul Manley, Michael Faller, BoYee Chung, Xin Chen, Philipp Busenhart, Christine Stephan, Keith Calkins, Debora Bonenfant, Claudio R. Thoma, William Forrester, James D. Griffin
Blood Cancer J. 2022 Jul; 12(7): 110. Published online 2022 Jul 19. doi: 10.1038/s41408-022-00704-7
PMCID:
PMC9296512
AbstractArticlePDF–2.4M
20.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M

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