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Select item 103116421.

Genetically programmed retinoic acid deficiency during gastrulation phenocopies most known developmental defects due to acute prenatal alcohol exposure in FASD

B. Petrelli, A. Oztürk, M. Pind, H. Ayele, A. Fainsod, G. G. Hicks

Front Cell Dev Biol. 2023; 11: 1208279. Published online 2023 Jun 16. doi: 10.3389/fcell.2023.1208279

PMCID:: PMC10311642

Abstract Article PDF–3.1M

Select item 102417892.

A multiple super-enhancer region establishes inter-TAD interactions and controls Hoxa function in cranial neural crest

Sandra Kessler, Maryline Minoux, Onkar Joshi, Yousra Ben Zouari, Sebastien Ducret, Fiona Ross, Nathalie Vilain, Adwait Salvi, Joachim Wolff, Hubertus Kohler, Michael B. Stadler, Filippo M. Rijli

Nat Commun. 2023; 14: 3242. Published online 2023 Jun 5. doi: 10.1038/s41467-023-38953-0

PMCID:: PMC10241789

Abstract Article PDF–6.6M

Select item 100278603.

Variations in the poly-histidine repeat motif of HOXA1 contribute to bicuspid aortic valve in mouse and zebrafish

Gaëlle Odelin, Adèle Faucherre, Damien Marchese, Amélie Pinard, Hager Jaouadi, Solena Le Scouarnec, FranceGenRef Consortium, Raphaël Chiarelli, Younes Achouri, Emilie Faure, Marine Herbane, Alexis Théron, Jean-François Avierinos, Chris Jopling, Gwenaëlle Collod-Béroud, René Rezsohazy, Stéphane Zaffran

Nat Commun. 2023; 14: 1543. Published online 2023 Mar 20. doi: 10.1038/s41467-023-37110-x

PMCID:: PMC10027860

Abstract Article PDF–11M

Select item 84517604.

Dbx2 regulation in limbs suggests interTAD sharing of enhancers

Leonardo Beccari, Gabriel Jaquier, Lucille Lopez‐Delisle, Eddie Rodriguez‐Carballo, Bénédicte Mascrez, Sandra Gitto, Joost Woltering, Denis Duboule

Dev Dyn. 2021 Sep; 250(9): 1280–1299. Published online 2021 Mar 1. doi: 10.1002/dvdy.303

PMCID:: PMC8451760

Abstract Article PDF–16M

Select item 78305215.

Hoxb3 Regulates Jag1 Expression in Pharyngeal Epithelium and Affects Interaction With Neural Crest Cells

Haoran Zhang, Junjie Xie, Karl Kam Hei So, Ka Kui Tong, Jearn Jang Sae-Pang, Li Wang, Sze Lan Tsang, Wood Yee Chan, Elaine Yee Man Wong, Mai Har Sham

Front Physiol. 2020; 11: 612230. Published online 2021 Jan 11. doi: 10.3389/fphys.2020.612230

PMCID:: PMC7830521

Abstract Article PDF–2.2M

Select item 77046666.

Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster

Yoshiki Higashijima, Nao Nagai, Masamichi Yamamoto, Taro Kitazawa, Yumiko K. Kawamura, Akashi Taguchi, Natsuko Nakada, Masaomi Nangaku, Tetsushi Furukawa, Hiroyuki Aburatani, Hiroki Kurihara, Youichiro Wada, Yasuharu Kanki

Commun Biol. 2020; 3: 725. Published online 2020 Nov 30. doi: 10.1038/s42003-020-01456-5

PMCID:: PMC7704666

Abstract Article PDF–1.3M

Select item 72599517.

Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates

Tempei Sato, Kensuke Kataoka, Yoshiaki Ito, Shigetoshi Yokoyama, Masafumi Inui, Masaki Mori, Satoru Takahashi, Keiichi Akita, Shuji Takada, Hiroe Ueno-Kudoh, Hiroshi Asahara

eLife. 2020; 9: e53608. Published online 2020 May 29. doi: 10.7554/eLife.53608

PMCID:: PMC7259951

Abstract Article PDF–5.5M

Select item 71908328.

LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development

Nicholas K. Vinckier, Nisha A. Patel, Ryan J. Geusz, Allen Wang, Jinzhao Wang, Ileana Matta, Austin R. Harrington, Matthew Wortham, Nichole Wetton, Jianxun Wang, Ulupi S. Jhala, Michael G. Rosenfeld, Christopher W. Benner, Hung-Ping Shih, Maike Sander

Nat Commun. 2020; 11: 2082. Published online 2020 Apr 29. doi: 10.1038/s41467-020-16017-x

PMCID:: PMC7190832

Abstract Article PDF–3.5M

Select item 67626599.

Generation of a Novel Functional Neuronal Circuit inHoxa1 Mutant Mice

Eduardo Domínguez del Toro, Véronique Borday, Marc Davenne, Rüdiger Neun, Filippo M. Rijli, Jean Champagnat

J Neurosci. 2001 Aug 1; 21(15): 5637–5642. doi: 10.1523/JNEUROSCI.21-15-05637.2001

PMCID:: PMC6762659

Abstract Article PDF–672K

Select item 671969710.

Single-cell analysis of cardiogenesis reveals basis for organ level developmental defects

T. Yvanka de Soysa, Sanjeev S. Ranade, Satoshi Okawa, Srikanth Ravichandran, Yu Huang, Hazel T. Salunga, Amelia Schricker, Antonio Del Sol, Casey A. Gifford, Deepak Srivastava

Nature. Author manuscript; available in PMC 2020 Jan 24.

Published in final edited form as: Nature. 2019 Aug; 572(7767): 120–124. Published online 2019 Jul 24. doi: 10.1038/s41586-019-1414-x

PMCID:: PMC6719697

Abstract Article PDF–8.9M

Select item 664971611.

A distal enhancer maintaining Hoxa1 expression orchestrates retinoic acid-induced early ESCs differentiation

Guangsong Su, Dianhao Guo, Jun Chen, Man Liu, Jian Zheng, Wenbin Wang, Xueyuan Zhao, Qingqing Yin, Lei Zhang, Zhongfang Zhao, Jiandang Shi, Wange Lu

Nucleic Acids Res. 2019 Jul 26; 47(13): 6737–6752. Published online 2019 May 31. doi: 10.1093/nar/gkz482

PMCID:: PMC6649716

Abstract Article PDF–7.1M

Select item 646668712.

Abnormal level of CUL4B-mediated histone H2A ubiquitination causes disruptive HOX gene expression

Ye Lin, Juan Yu, Jianxin Wu, Shan Wang, Ting Zhang

Epigenetics Chromatin. 2019; 12: 22. Published online 2019 Apr 16. doi: 10.1186/s13072-019-0268-7

PMCID:: PMC6466687

Abstract Article PDF–3.0M

Select item 645219813.

FOXF2 is required for cochlear development in humans and mice

Guney Bademci, Clemer Abad, Armagan Incesulu, Fahed Elian, Azadeh Reyahi, Oscar Diaz-Horta, Filiz B Cengiz, Claire J Sineni, Serhat Seyhan, Emine Ikbal Atli, Hikmet Basmak, Selma Demir, Ali Moussavi Nik, Tim Footz, Shengru Guo, Duygu Duman, Suat Fitoz, Hakan Gurkan, Susan H Blanton, Michael A Walter, Peter Carlsson, Katherina Walz, Mustafa Tekin

Hum Mol Genet. 2019 Apr 15; 28(8): 1286–1297. Published online 2018 Dec 17. doi: 10.1093/hmg/ddy431

PMCID:: PMC6452198

Abstract Article PDF–46M

Select item 611839314.

Ablation of Ezh2 in neural crest cells leads to aberrant enteric nervous system development in mice

Hana Kim, Ingeborg M. Langohr, Mohammad Faisal, Margaret McNulty, Caitlin Thorn, Joomyeong Kim

PLoS One. 2018; 13(8): e0203391. Published online 2018 Aug 31. doi: 10.1371/journal.pone.0203391

PMCID:: PMC6118393

Abstract Article PDF–20M

Select item 558071015.

HOXA1 and TALE proteins display cross-regulatory interactions and form a combinatorial binding code on HOXA1 targets

Bony De Kumar, Hugo J. Parker, Ariel Paulson, Mark E. Parrish, Irina Pushel, Narendra Pratap Singh, Ying Zhang, Brian D. Slaughter, Jay R. Unruh, Laurence Florens, Julia Zeitlinger, Robb Krumlauf

Genome Res. 2017 Sep; 27(9): 1501–1512. doi: 10.1101/gr.219386.116