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Items: 1 to 20 of 51

1.
SHLD1 is dispensable for 53BP1-dependent V(D)J recombination but critical for productive class switch recombination
Estelle Vincendeau, Wenming Wei, Xuefei Zhang, Cyril Planchais, Wei Yu, Hélène Lenden-Hasse, Thomas Cokelaer, Juliana Pipoli da Fonseca, Hugo Mouquet, David J. Adams, Frederick W. Alt, Stephen P. Jackson, Gabriel Balmus, Chloé Lescale, Ludovic Deriano
Nat Commun. 2022; 13: 3707. Published online 2022 Jun 28. doi: 10.1038/s41467-022-31287-3
PMCID:
PMC9240092
AbstractArticlePDF–3.7M
2.
An XRCC4 mutant mouse, a model for human X4 syndrome, reveals interplays with Xlf, PAXX, and ATM in lymphoid development
Benoit Roch, Vincent Abramowski, Olivier Etienne, Stefania Musilli, Pierre David, Jean-Baptiste Charbonnier, Isabelle Callebaut, François D Boussin, Jean-Pierre de Villartay
eLife. 2021; 10: e69353. Published online 2021 Sep 14. doi: 10.7554/eLife.69353
PMCID:
PMC8516412
AbstractArticlePDF–10M
3.
DNA damage–induced phosphorylation of CtIP at a conserved ATM/ATR site T855 promotes lymphomagenesis in mice
Xiaobin S. Wang, Demis Menolfi, Foon Wu-Baer, Marco Fangazio, Stefanie N. Meyer, Zhengping Shao, Yunyue Wang, Yimeng Zhu, Brian J. Lee, Verna M. Estes, Olivia M. Cupo, Jean Gautier, Laura Pasqualucci, Riccardo Dalla-Favera, Richard Baer, Shan Zha
Proc Natl Acad Sci U S A. 2021 Sep 21; 118(38): e2105440118. Published online 2021 Sep 14. doi: 10.1073/pnas.2105440118
PMCID:
PMC8463888
AbstractArticlePDF–2.1M
4.
CtIP-mediated DNA resection is dispensable for IgH class switch recombination by alternative end-joining
Xiaobin S. Wang, Junfei Zhao, Foon Wu-Baer, Zhengping Shao, Brian J. Lee, Olivia M. Cupo, Raul Rabadan, Jean Gautier, Richard Baer, Shan Zha
Proc Natl Acad Sci U S A. 2020 Oct 13; 117(41): 25700–25711. Published online 2020 Sep 28. doi: 10.1073/pnas.2010972117
PMCID:
PMC7568320
AbstractArticlePDF–2.4M
5.
Kinase-dependent structural role of DNA-PKcs during immunoglobulin class switch recombination
Jennifer L. Crowe, Zhengping Shao, Xiaobin S. Wang, Pei-Chi Wei, Wenxia Jiang, Brian J. Lee, Verna M. Estes, Frederick W. Alt, Shan Zha
Proc Natl Acad Sci U S A. 2018 Aug 21; 115(34): 8615–8620. Published online 2018 Aug 2. doi: 10.1073/pnas.1808490115
PMCID:
PMC6112704
AbstractArticlePDF–1.2M
6.
Germline Chd8 haploinsufficiency alters brain development in mouse
Andrea L. Gompers, Linda Su-Feher, Jacob Ellegood, Nycole A. Copping, M. Asrafuzzaman Riyadh, Tyler W. Stradleigh, Michael C. Pride, Melanie D. Schaffler, A. Ayanna Wade, Rinaldo Catta-Preta, Iva Zdilar, Shreya Louis, Gaurav Kaushik, Brandon J. Mannion, Ingrid Plajzer-Frick, Veena Afzal, Axel Visel, Len A. Pennacchio, Diane E. Dickel, Jason P. Lerch, Jacqueline N. Crawley, Konstantinos S. Zarbalis, Jill L. Silverman, Alex S. Nord
Nat Neurosci. Author manuscript; available in PMC 2018 Jun 19.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1062–1073. Published online 2017 Jun 26. doi: 10.1038/nn.4592
PMCID:
PMC6008102
AbstractArticlePDF–1.8M
7.
PAXX and Xlf interplay revealed by impaired CNS development and immunodeficiency of double KO mice
Vincent Abramowski, Olivier Etienne, Ramy Elsaid, Junjie Yang, Aurélie Berland, Laetitia Kermasson, Benoit Roch, Stefania Musilli, Jean-Paul Moussu, Karelia Lipson-Ruffert, Patrick Revy, Ana Cumano, François D Boussin, Jean-Pierre de Villartay
Cell Death Differ. 2018 Feb; 25(2): 444–452. Published online 2017 Oct 27. doi: 10.1038/cdd.2017.184
PMCID:
PMC5762856
AbstractArticlePDF–3.3M
8.
Synthetic lethality between murine DNA repair factors XLF and DNA-PKcs is rescued by inactivation of Ku70
Mengtan Xing, Magnar Bjørås, Jeremy A. Daniel, Frederick W. Alt, Valentyn Oksenych
DNA Repair (Amst) Author manuscript; available in PMC 2018 Sep 1.
Published in final edited form as: DNA Repair (Amst). 2017 Sep; 57: 133–138. Published online 2017 Jul 26. doi: 10.1016/j.dnarep.2017.07.008
PMCID:
PMC5584571
AbstractArticlePDF–793K
9.
Contribution of canonical nonhomologous end joining to chromosomal rearrangements is enhanced by ATM kinase deficiency
Ragini Bhargava, Caree R. Carson, Gabriella Lee, Jeremy M. Stark
Proc Natl Acad Sci U S A. 2017 Jan 24; 114(4): 728–733. Published online 2017 Jan 5. doi: 10.1073/pnas.1612204114
PMCID:
PMC5278456
AbstractArticlePDF–1.1M
10.
Contribution of classical end-joining to PTEN inactivation in p53-mediated glioblastoma formation and drug-resistant survival
Youn-Jung Kang, Barbara Balter, Eva Csizmadia, Brian Haas, Himanshu Sharma, Roderick Bronson, Catherine T. Yan
Nat Commun. 2017; 8: 14013. Published online 2017 Jan 17. doi: 10.1038/ncomms14013
Correction in:
Nat Commun. 2017; 8: 15795.
PMCID:
PMC5247582
AbstractArticlePDF–4.5M
11.
Complex Breakpoints and Template Switching Associated with Non-canonical Termination of Homologous Recombination in Mammalian Cells
Andrea J. Hartlerode, Nicholas A. Willis, Anbazhagan Rajendran, John P. Manis, Ralph Scully
PLoS Genet. 2016 Nov; 12(11): e1006410. Published online 2016 Nov 10. doi: 10.1371/journal.pgen.1006410
Correction in:
PLoS Genet. 2016 Dec; 12(12): e1006509.
PMCID:
PMC5104497
AbstractArticlePDF–2.3M
12.
Unexpected effects of different genetic backgrounds on identification of genomic rearrangements via whole-genome next generation sequencing
Zhangguo Chen, Katherine Gowan, Sonia M. Leach, Sawanee S. Viboolsittiseri, Ameet K. Mishra, Tanya Kadoishi, Katrina Diener, Bifeng Gao, Kenneth Jones, Jing H. Wang
BMC Genomics. 2016; 17: 823. Published online 2016 Oct 21. doi: 10.1186/s12864-016-3153-9
PMCID:
PMC5075209
AbstractArticlePDF–4.5M
13.
Tissue-Specific Effects of Valproic Acid on DNA Repair Genes and Apoptosis in Postimplantation Mouse Embryos
Christina Lamparter, Louise M. Winn
Toxicol Sci. 2014 Sep 1; 141(1): 59–67. Published online 2014 Sep 12. doi: 10.1093/toxsci/kfu105
PMCID:
PMC4833099
AbstractArticlePDF–1.6M
14.
FBXW7 facilitates non-homologous end-joining via K63-linked polyubiquitylation of XRCC4
Qiang Zhang, David Karnak, Mingjia Tan, Theodore S. Lawrence, Meredith A. Morgan, Yi Sun
Mol Cell. Author manuscript; available in PMC 2017 Feb 4.
Published in final edited form as: Mol Cell. 2016 Feb 4; 61(3): 419–433. Published online 2016 Jan 7. doi: 10.1016/j.molcel.2015.12.010
PMCID:
PMC4744117
AbstractArticlePDF–2.6M
15.
Combined deletion of Xrcc4 and Trp53 in mouse germinal center B cells leads to novel B cell lymphomas with clonal heterogeneity
Zhangguo Chen, Mihret T. Elos, Sawanee S. Viboolsittiseri, Katherine Gowan, Sonia M. Leach, Michael Rice, Maxwell D. Eder, Kenneth Jones, Jing H. Wang
J Hematol Oncol. 2016; 9: 2. Published online 2016 Jan 7. doi: 10.1186/s13045-015-0230-5
PMCID:
PMC4704435
AbstractArticlePDF–3.4M
16.
Differential phosphorylation of DNA-PKcs regulates the interplay between end-processing and end-ligation during non-homologous end-joining
Wenxia Jiang, Jennifer L. Crowe, Xiangyu Liu, Satoshi Nakajima, Yunyue Wang, Chen Li, Brian J. Lee, Richard L. Dubois, Chao Liu, Xiaochun Yu, Li Lan, Shan Zha
Mol Cell. Author manuscript; available in PMC 2016 Apr 2.
Published in final edited form as: Mol Cell. 2015 Apr 2; 58(1): 172–185. Published online 2015 Mar 26. doi: 10.1016/j.molcel.2015.02.024
PMCID:
PMC4415111
AbstractArticlePDF–3.0M
17.
Ionizing radiation-induced XRCC4 phosphorylation is mediated through ATM in addition to DNA-PK
Shoji IMAMICHI, Mukesh Kumar SHARMA, Radhika Pankaj KAMDAR, Mikoto FUKUCHI, Yoshihisa MATSUMOTO
Proc Jpn Acad Ser B Phys Biol Sci. 2014 Nov 11; 90(9): 365–372. doi: 10.2183/pjab.90.365
PMCID:
PMC4324928
AbstractArticlePDF–390K
18.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
19.
Functional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joining
Valentyn Oksenych, Vipul Kumar, Xiangyu Liu, Chunguang Guo, Bjoern Schwer, Shan Zha, Frederick W. Alt
Proc Natl Acad Sci U S A. 2013 Feb 5; 110(6): 2234–2239. Published online 2013 Jan 23. doi: 10.1073/pnas.1222573110
PMCID:
PMC3568359
AbstractArticlePDF–711K
20.
De Novo CNV Formation in Mouse Embryonic Stem Cells Occurs in the Absence of Xrcc4-Dependent Nonhomologous End Joining
Martin F. Arlt, Sountharia Rajendran, Shanda R. Birkeland, Thomas E. Wilson, Thomas W. Glover
PLoS Genet. 2012 Sep; 8(9): e1002981. Published online 2012 Sep 20. doi: 10.1371/journal.pgen.1002981
PMCID:
PMC3447954
AbstractArticlePDF–902K

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