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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108552042.

Involvement of the Na⁺, K⁺-ATPase α1 Isoform and Endogenous Cardiac Steroids in Depression- and Manic-like Behaviors

Noa Horesh, Ilana Pelov, Ilana Pogodin, Hiba Zannadeh, Haim Rosen, Anastasiia Leonidovna Mikhrina, Moran Dvela-Levitt, Vishnu Priya Sampath, David Lichtstein

Int J Mol Sci. 2024 Feb; 25(3): 1644. Published online 2024 Jan 29. doi: 10.3390/ijms25031644

PMCID:: PMC10855204

Abstract Article PDF–1.6M

Select item 107693503.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 105722094.

Normalization of the ATP1A1 Signalosome Rescinds Epigenetic Modifications and Induces Cell Autophagy in Hepatocellular Carcinoma

Pradeep Kumar Rajan, Utibe-Abasi S. Udoh, Yuto Nakafuku, Sandrine V. Pierre, Juan Sanabria

Cells. 2023 Oct; 12(19): 2367. Published online 2023 Sep 27. doi: 10.3390/cells12192367

PMCID:: PMC10572209

Abstract Article PDF–5.7M

Select item 102682405.

ZBTB20 is essential for cochlear maturation and hearing in mice

Zhifang Xie, Xian-Hua Ma, Qiu-Fang Bai, Jie Tang, Jian-He Sun, Fei Jiang, Wei Guo, Chen-Ma Wang, Rui Yang, Yin-Chuan Wen, Fang-Yuan Wang, Yu-Xia Chen, Hai Zhang, David Z. He, Matthew W. Kelley, Shiming Yang, Weiping J. Zhang

Proc Natl Acad Sci U S A. 2023 Jun 13; 120(24): e2220867120. Published online 2023 Jun 6. doi: 10.1073/pnas.2220867120

PMCID:: PMC10268240

Abstract Article PDF–7.7M

Select item 99382166.

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes

Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x

PMCID:: PMC9938216

Abstract Article PDF–5.3M

Select item 96038607.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 95641928.

PGC-1α4 Interacts with REST to Upregulate Neuronal Genes and Augment Energy Consumption in Developing Cardiomyocytes

Tomi Tuomainen, Nikolay Naumenko, Maija Mutikainen, Anastasia Shakirzyanova, Sarah Sczelecki, Jennifer L. Estall, Jorge L. Ruas, Pasi Tavi

Cells. 2022 Oct; 11(19): 2944. Published online 2022 Sep 20. doi: 10.3390/cells11192944

PMCID:: PMC9564192

Abstract Article PDF–3.2M

Select item 94819339.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 944236110.

Na/K-ATPase suppresses LPS-induced pro-inflammatory signaling through Lyn

Jue Zhang, Jackie Chang, Mirza Ahmar Beg, Wenxin Huang, Yiqiong Zhao, Wen Dai, Xiaopeng Wu, Weiguo Cui, Sneha S. Pillai, Hari Vishal Lakhani, Komal Sodhi, Joseph I. Shapiro, Daisy Sahoo, Ze Zheng, Roy L. Silverstein, Yiliang Chen

iScience. 2022 Sep 16; 25(9): 104963. Published online 2022 Aug 17. doi: 10.1016/j.isci.2022.104963

PMCID:: PMC9442361

Abstract Article PDF–3.6M

Select item 902285511.

A real-time PCR method to genotype mutant mouse models with altered affinity for cardiotonic steroids on the Na,K-ATPase

Peter W. Chomczynski, Kianna M. Vires, Michal Rymaszewski, Judith A. Heiny

PLoS One. 2022; 17(4): e0267348. Published online 2022 Apr 21. doi: 10.1371/journal.pone.0267348

PMCID:: PMC9022855

Abstract Article PDF–1.2M

Select item 896988412.

PPAR-α knockout leads to elevated blood pressure response to angiotensin II infusion associated with an increase in renal α-1 Na⁺/K⁺ ATPase protein expression and activity

Syed J. Khundmiri, Carolyn M. Ecelbarger, Joycemary Amponsem, Hong Ji, Kathryn Sandberg, Dexter L. Lee

Life Sci. Author manuscript; available in PMC 2023 May 1.

Published in final edited form as: Life Sci. 2022 May 1; 296: 120444. Published online 2022 Mar 1. doi: 10.1016/j.lfs.2022.120444

Correction in:: Life Sci. 2023 Oct 15; 331: 122068.

PMCID:: PMC8969884

Abstract Article PDF–761K

Select item 863166213.

The cellular prion protein interacts with and promotes the activity of Na,K-ATPases

Declan Williams, Mohadeseh Mehrabian, Hamza Arshad, Shehab Eid, Christopher Sackmann, Wenda Zhao, Xinzhu Wang, Farinaz Ghodrati, Claire E. Verkuyl, Joel C. Watts, Gerold Schmitt-Ulms

PLoS One. 2021; 16(11): e0258682. Published online 2021 Nov 30. doi: 10.1371/journal.pone.0258682

PMCID:: PMC8631662

Abstract Article PDF–3.1M

Select item 857053414.

The Na/K-ATPase α1/Src interaction regulates metabolic reserve and Western diet intolerance

Laura C Kutz, Xiaoyu Cui, Jeffrey X. Xie, Shreya T Mukherji, Kayleigh C Terrell, Minqi Huang, Xiaoliang Wang, Jiayan Wang, Adam J Martin, Marco T Pessoa, Liquan Cai, Hua Zhu, Judith A Heiny, Joseph I Shapiro, Gustavo Blanco, Zijian Xie, Sandrine V Pierre

Acta Physiol (Oxf) Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: Acta Physiol (Oxf). 2021 Jul; 232(3): e13652. Published online 2021 Apr 4. doi: 10.1111/apha.13652

PMCID:: PMC8570534

Abstract Article PDF–3.0M

Select item 848125015.

Vacuolar-type proton ATPase is required for maintenance of apicobasal polarity of embryonic visceral endoderm

Ge-Hong Sun-Wada, Hiroyuki Tabata, Yoh Wada

Sci Rep. 2021; 11: 19355. Published online 2021 Sep 29. doi: 10.1038/s41598-021-98952-3

PMCID:: PMC8481250

Abstract Article PDF–3.5M

Select item 831323916.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 828286017.

Spatio-temporal expression pattern and role of the tight junction protein MarvelD3 in pancreas development and function

Charlotte Heymans, Ophélie Delcorte, Catherine Spourquet, Mylah Villacorte-Tabelin, Sébastien Dupasquier, Younes Achouri, Siam Mahibullah, Pascale Lemoine, Maria S. Balda, Karl Matter, Christophe E. Pierreux

Sci Rep. 2021; 11: 14519. Published online 2021 Jul 15. doi: 10.1038/s41598-021-93654-2

PMCID:: PMC8282860

Abstract Article PDF–6.6M

Select item 813767518.

Cochlear supporting cells require GAS2 for cytoskeletal architecture and hearing

Tingfang Chen, Alex M. Rohacek, Matthew Caporizzo, Amir Nankali, Jeroen J. Smits, Jaap Oostrik, Cornelis P. Lanting, Erdi Kücük, Christian Gilissen, Jiddeke M. van de Kamp, Ronald J.E. Pennings, Staci M. Rakowiecki, Klaus H. Kaestner, Kevin K. Ohlemiller, John S. Oghalai, Hannie Kremer, Benjamin L. Prosser, Douglas J. Epstein

Dev Cell. Author manuscript; available in PMC 2022 May 17.

Published in final edited form as: Dev Cell. 2021 May 17; 56(10): 1526–1540.e7. Published online 2021 May 7. doi: 10.1016/j.devcel.2021.04.017

PMCID:: PMC8137675

Abstract Article PDF–3.8M

Select item 803899619.

The Ncoa7 locus regulates V-ATPase formation and function, neurodevelopment and behaviour

Enrico Castroflorio, Joery den Hoed, Daria Svistunova, Mattéa J. Finelli, Alberto Cebrian-Serrano, Silvia Corrochano, Andrew R. Bassett, Benjamin Davies, Peter L. Oliver

Cell Mol Life Sci. 2021 Apr; 78(7): 3503–3524. Published online 2020 Dec 19. doi: 10.1007/s00018-020-03721-6

PMCID:: PMC8038996

Abstract Article PDF–6.4M

Select item 801959620.

Tsg101 Is Necessary for the Establishment and Maintenance of Mouse Retinal Pigment Epithelial Cell Polarity

Dai Le, Soyeon Lim, Kwang Wook Min, Joon Woo Park, Youjoung Kim, Taejeong Ha, Kyeong Hwan Moon, Kay-Uwe Wagner, Jin Woo Kim

Mol Cells. 2021 Mar 31; 44(3): 168–178. Published online 2021 Mar 28. doi: 10.14348/molcells.2021.0027

PMCID:: PMC8019596

Abstract Article PDF–34M

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