PMC Links for GEO Profiles (Select 63839797) - PMC

Select item 81091341.

Inhibition of sestrin 1 alleviates polycystic ovary syndrome by decreasing autophagy

Xiaoyuan Xu, Xinli Song, Xiaohua Xu, Yanluan Zheng, Lan Xu, Ling Shen

Aging (Albany NY) 2021 Apr 30; 13(8): 11774–11785. Published online 2021 Apr 22. doi: 10.18632/aging.202872

PMCID:: PMC8109134

Abstract Article PDF–1.3M

Select item 65801702.

Evidence for a role for Sestrin1 in mediating leucine-induced activation of mTORC1 in skeletal muscle

Dandan Xu, Kevin L. Shimkus, Holly A. Lacko, Lydia Kutzler, Leonard S. Jefferson, Scot R. Kimball

Am J Physiol Endocrinol Metab. 2019 May 1; 316(5): E817–E828. Published online 2019 Mar 5. doi: 10.1152/ajpendo.00522.2018

PMCID:: PMC6580170

Abstract Article

Select item 46980173.

Sestrin2 is a leucine sensor for the mTORC1 pathway

Rachel L. Wolfson, Lynne Chantranupong, Robert A. Saxton, Kuang Shen, Sonia M. Scaria, Jason R. Cantor, David M. Sabatini

Science. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Science. 2016 Jan 1; 351(6268): 43–48. Published online 2015 Oct 8. doi: 10.1126/science.aab2674

PMCID:: PMC4698017

Abstract Article PDF–1.4M

Select item 42238664.

The Sestrins interact with GATOR2 to negatively regulate the amino acid sensing pathway upstream of mTORC1

Lynne Chantranupong, Rachel L. Wolfson, Jose M. Orozco, Robert A. Saxton, Sonia M. Scaria, Liron Bar-Peled, Eric Spooner, Marta Isasa, Steven P. Gygi, David M. Sabatini

Cell Rep. Author manuscript; available in PMC 2014 Nov 7.

Published in final edited form as: Cell Rep. 2014 Oct 9; 9(1): 1–8. Published online 2014 Sep 25. doi: 10.1016/j.celrep.2014.09.014

PMCID:: PMC4223866

Abstract Article PDF–616K

Select item 41813525.

Sestrins Function as Guanine Nucleotide Dissociation Inhibitors for Rag GTPases to Control mTORC1 Signaling

Min Peng, Na Yin, Ming O. Li

Cell. Author manuscript; available in PMC 2015 Sep 25.

Published in final edited form as: Cell. 2014 Sep 25; 159(1): 122–133. doi: 10.1016/j.cell.2014.08.038

PMCID:: PMC4181352

Abstract Article PDF–2.7M

Select item 36873656.

Maintenance of metabolic homeostasis by Sestrin 2 and 3

Jun Hee Lee, Andrei V. Budanov, Saswata Talukdar, Eek Joong Park, Hae Li Park, Hwan-Woo Park, Gautam Bandyopadhyay, Ning Li, Mariam Aghajan, Insook Jang, Amber M. Wolfe, Guy A. Perkins, Mark H. Ellisman, Ethan Bier, Miriam Scadeng, Marc Foretz, Benoit Viollet, Jerrold Olefsky, Michael Karin

Cell Metab. Author manuscript; available in PMC 2013 Jun 20.

Published in final edited form as: Cell Metab. 2012 Sep 5; 16(3): 311–321. doi: 10.1016/j.cmet.2012.08.004

PMCID:: PMC3687365

Abstract Article PDF–5.0M

Select item 31780597.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 28666328.

Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies

Jun Hee Lee, Andrei V. Budanov, Eek Joong Park, Ryan Birse, Teddy E. Kim, Guy A. Perkins, Karen Ocorr, Mark H. Ellisman, Rolf Bodmer, Ethan Bier, Michael Karin

Science. Author manuscript; available in PMC 2011 Mar 5.

Published in final edited form as: Science. 2010 Mar 5; 327(5970): 1223–1228. doi: 10.1126/science.1182228

PMCID:: PMC2866632

Abstract Article PDF–2.3M

Select item 27585229.

The p53-regulated Sestrin gene products inhibit mTOR signaling

Andrei V. Budanov, Michael Karin

Cell. Author manuscript; available in PMC 2009 Oct 7.

Published in final edited form as: Cell. 2008 Aug 8; 134(3): 451–460. doi: 10.1016/j.cell.2008.06.028

Correction in:: volume 136 on page 378

PMCID:: PMC2758522

Abstract Article PDF–1.7M

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