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Select item 95394631.

DDX3X alleviates doxorubicin‐induced cardiotoxicity by regulating Wnt/β‐catenin signaling pathway in an in vitro model

Dandan Feng, Jiang Li, Liang Guo, Jing Liu, Shaochen Wang, Xiuyuan Ma, Yunxuan Song, Ju Liu, Enkui Hao

J Biochem Mol Toxicol. 2022 Aug; 36(8): e23077. Published online 2022 Apr 25. doi: 10.1002/jbt.23077

PMCID:: PMC9539463

Abstract Article PDF–1.7M

Select item 69802842.

DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome

Parimal Samir, Sannula Kesavardhana, Deanna M. Patmore, Sebastien Gingras, R. K. Subbarao Malireddi, Rajendra Karki, Clifford S. Guy, Benoit Briard, David E. Place, Anannya Bhattacharya, Bhesh raj Sharma, Amanda Nourse, Sharon V. King, Aaron Pitre, Amanda R. Burton, Stephane Pelletier, Richard J. Gilbertson, Thirumala-Devi Kanneganti

Nature. Author manuscript; available in PMC 2020 Mar 11.

Published in final edited form as: Nature. 2019 Sep; 573(7775): 590–594. Published online 2019 Sep 11. doi: 10.1038/s41586-019-1551-2

PMCID:: PMC6980284

Abstract Article PDF–5.6M

Select item 66859813.

Avenanthramide A triggers potent ROS-mediated anti-tumor effects in colorectal cancer by directly targeting DDX3

Rong Fu, Peng Yang, Zongwei Li, Wen Liu, Sajid Amin, Zhuoyu Li

Cell Death Dis. 2019 Aug; 10(8): 593. Published online 2019 Aug 7. doi: 10.1038/s41419-019-1825-5

PMCID:: PMC6685981

Abstract Article PDF–10M

Select item 59980474.

The TRPV4 channel links calcium influx to DDX3X activity and viral infectivity

P. Doñate-Macián, J. Jungfleisch, G. Pérez-Vilaró, F. Rubio-Moscardo, A. Perálvarez-Marín, J. Diez, M. A. Valverde

Nat Commun. 2018; 9: 2307. Published online 2018 Jun 13. doi: 10.1038/s41467-018-04776-7

PMCID:: PMC5998047

Abstract Article PDF–3.6M

Select item 56538215.

DDX3 regulates endoplasmic reticulum stress-induced ATF4 expression

Pauline Adjibade, Valérie Grenier St-Sauveur, Jonathan Bergeman, Marc-Etienne Huot, Edouard W. Khandjian, Rachid Mazroui

Sci Rep. 2017; 7: 13832. Published online 2017 Oct 23. doi: 10.1038/s41598-017-14262-7

PMCID:: PMC5653821

Abstract Article PDF–1.9M

Select item 55775056.

The helicase, DDX3X, interacts with poly(A)-binding protein 1 (PABP1) and caprin-1 at the leading edge of migrating fibroblasts and is required for efficient cell spreading

Alice C. Copsey, Simon Cooper, Robert Parker, Ella Lineham, Cuzack Lapworth, Deema Jallad, Steve Sweet, Simon J. Morley

Biochem J. 2017 Sep 15; 474(18): 3109–3120. Prepublished online 2017 Jul 21. Published online 2017 Aug 31. doi: 10.1042/BCJ20170354

PMCID:: PMC5577505

Abstract Article PDF–972K

Select item 55733517.

DDX3 localizes to the centrosome and prevents multipolar mitosis by epigenetically and translationally modulating p53 expression

Wei-Ju Chen, Wei-Ting Wang, Tsung-Yuan Tsai, Hao-Kang Li, Yan-Hwa Wu Lee

Sci Rep. 2017; 7: 9411. Published online 2017 Aug 25. doi: 10.1038/s41598-017-09779-w

PMCID:: PMC5573351

Abstract Article PDF–15M

Select item 55610608.

Genome-wide identification and expression profiling of long non-coding RNAs in auditory and vestibular systems

Kathy Ushakov, Tal Koffler-Brill, Aviv Rom, Kobi Perl, Igor Ulitsky, Karen B. Avraham

Sci Rep. 2017; 7: 8637. Published online 2017 Aug 17. doi: 10.1038/s41598-017-08320-3

PMCID:: PMC5561060

Abstract Article PDF–4.9M

Select item 52697339.

RNA helicase DDX3 maintains lipid homeostasis through upregulation of the microsomal triglyceride transfer protein by interacting with HNF4 and SHP

Tsung-Yuan Tsai, Wei-Ting Wang, Hao-Kang Li, Wei-Ju Chen, Yu-Hong Tsai, Chi-Hong Chao, Yan-Hwa Wu Lee

Sci Rep. 2017; 7: 41452. Published online 2017 Jan 27. doi: 10.1038/srep41452

PMCID:: PMC5269733

Abstract Article PDF–2.2M

Select item 506334710.

The DEAD-Box RNA Helicase DDX3 Interacts with NF-κB Subunit p65 and Suppresses p65-Mediated Transcription

Nian Xiang, Miao He, Musarat Ishaq, Yu Gao, Feifei Song, Liang Guo, Li Ma, Guihong Sun, Dan Liu, Deyin Guo, Yu Chen

PLoS One. 2016; 11(10): e0164471. Published online 2016 Oct 13. doi: 10.1371/journal.pone.0164471

PMCID:: PMC5063347

Abstract Article PDF–3.4M

Select item 501046811.

RNA remodeling activity of DEAD-box proteins tuned by protein concentration, RNA length and ATP

Younghoon Kim, Sua Myong

Mol Cell. Author manuscript; available in PMC 2017 Sep 1.

Published in final edited form as: Mol Cell. 2016 Sep 1; 63(5): 865–876. Published online 2016 Aug 18. doi: 10.1016/j.molcel.2016.07.010

PMCID:: PMC5010468

Abstract Article PDF–2.8M

Select item 500839212.

DDX3 enhances oncogenic KRAS-induced tumor invasion in colorectal cancer via the β-catenin/ZEB1 axis

De-Wei Wu, Po-Lin Lin, Ya-Wen Cheng, Chi-Chou Huang, Lee Wang, Huei Lee

Oncotarget. 2016 Apr 19; 7(16): 22687–22699. Published online 2016 Mar 17. doi: 10.18632/oncotarget.8143

PMCID:: PMC5008392

Abstract Article PDF–5.9M

Select item 497239713.

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

Zhenhuan Guo, Lisa J Neilson, Hang Zhong, Paul S Murray, Megha Vaman Rao, Sara Zanivan, Ronen Zaidel-Bar

Sci Signal. Author manuscript; available in PMC 2016 Aug 3.

Published in final edited form as: Sci Signal. 2014 Dec 2; 7(354): rs7. Published online 2014 Dec 2. doi: 10.1126/scisignal.2005473

PMCID:: PMC4972397

Abstract Article PDF–3.1M

Select item 475958814.

DDX3 promotes tumor invasion in colorectal cancer via the CK1ε/Dvl2 axis

Tsung-Ying He, De-Wei Wu, Po-Lin Lin, Lee Wang, Chi-Chou Huang, Ming-Chih Chou, Huei Lee

Sci Rep. 2016; 6: 21483. Published online 2016 Feb 19. doi: 10.1038/srep21483

PMCID:: PMC4759588

Abstract Article PDF–1.5M

Select item 462191315.

DDX3 as a strongest prognosis marker and its downregulation promotes metastasis in colorectal cancer

Chia-Yi Su, Tsung-Chieh Lin, Yuan-Feng Lin, Ming-Huang Chen, Chien-Hsin Lee, Hsuan-Yao Wang, Yu-Chieh Lee, Yu-Peng Liu, Chi-Long Chen, Michael Hsiao

Oncotarget. 2015 Jul 30; 6(21): 18602–18612. Published online 2015 Jun 2. doi: 10.18632/oncotarget.4329

PMCID:: PMC4621913

Abstract Article PDF–4.2M

Select item 457324416.

Mutations in DDX3X Are a Common Cause of Unexplained Intellectual Disability with Gender-Specific Effects on Wnt Signaling

Lot Snijders Blok, Erik Madsen, Jane Juusola, Christian Gilissen, Diana Baralle, Margot R.F. Reijnders, Hanka Venselaar, Céline Helsmoortel, Megan T. Cho, Alexander Hoischen, Lisenka E.L.M. Vissers, Tom S. Koemans, Willemijn Wissink-Lindhout, Evan E. Eichler, Corrado Romano, Hilde Van Esch, Connie Stumpel, Maaike Vreeburg, Eric Smeets, Karin Oberndorff, Bregje W.M. van Bon, Marie Shaw, Jozef Gecz, Eric Haan, Melanie Bienek, Corinna Jensen, Bart L. Loeys, Anke Van Dijck, A. Micheil Innes, Hilary Racher, Sascha Vermeer, Nataliya Di Donato, Andreas Rump, Katrina Tatton-Brown, Michael J. Parker, Alex Henderson, Sally A. Lynch, Alan Fryer, Alison Ross, Pradeep Vasudevan, Usha Kini, Ruth Newbury-Ecob, Kate Chandler, Alison Male, the DDD Study, Sybe Dijkstra, Jolanda Schieving, Jacques Giltay, Koen L.I. van Gassen, Janneke Schuurs-Hoeijmakers, Perciliz L. Tan, Igor Pediaditakis, Stefan A. Haas, Kyle Retterer, Patrick Reed, Kristin G. Monaghan, Eden Haverfield, Marvin Natowicz, Angela Myers, Michael C. Kruer, Quinn Stein, Kevin A. Strauss, Karlla W. Brigatti, Katherine Keating, Barbara K. Burton, Katherine H. Kim, Joel Charrow, Jennifer Norman, Audrey Foster-Barber, Antonie D. Kline, Amy Kimball, Elaine Zackai, Margaret Harr, Joyce Fox, Julie McLaughlin, Kristin Lindstrom, Katrina M. Haude, Kees van Roozendaal, Han Brunner, Wendy K. Chung, R. Frank Kooy, Rolph Pfundt, Vera Kalscheuer, Sarju G. Mehta, Nicholas Katsanis, Tjitske Kleefstra

Am J Hum Genet. 2015 Aug 6; 97(2): 343–352. doi: 10.1016/j.ajhg.2015.07.004