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Select item 113735991.

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway

Elena Prosdocimi, Veronica Carpanese, Luca Matteo Todesca, Tatiana Varanita, Magdalena Bachmann, Margherita Festa, Daniele Bonesso, Mireia Perez-Verdaguer, Andrea Carrer, Angelo Velle, Roberta Peruzzo, Silvia Muccioli, Davide Doni, Luigi Leanza, Paola Costantini, Frank Stein, Mandy Rettel, Antonio Felipe, Michael J. Edwards, Erich Gulbins, Laura Cendron, Chiara Romualdi, Vanessa Checchetto, Ildiko Szabo

Sci Adv. 2024 Sep 6; 10(36): eadn9361. Published online 2024 Sep 4. doi: 10.1126/sciadv.adn9361

PMCID:: PMC11373599

Abstract Article PDF–11M

Select item 113447042.

XTP8 Promotes Ovarian Cancer Progression by Activating AKT/AMPK/mTOR Pathway to Regulate EMT

Ruixue Zhao, Xin Ning, Hongping Lu, Wei Xu, Jiaxin Ma, Jun Cheng, Rong Ma

Cell Biochem Biophys. 2024; 82(2): 945–957. Published online 2024 Mar 13. doi: 10.1007/s12013-024-01246-4

PMCID:: PMC11344704

Abstract Article PDF–2.7M

Select item 109457073.

Comparative interactome analysis of α-arrestin families in human and Drosophila

Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam

eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328

PMCID:: PMC10945707

Abstract Article PDF–2.8M

Select item 109168664.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 106356595.

DEPDC1B-mediated USP5 deubiquitination of β-catenin promotes breast cancer metastasis by activating the wnt/β-catenin pathway

Qingqing Wang, Fengxia Chen, Ningning Yang, Lu Xu, Xiaoyan Yu, Meng Wu, Yunfeng Zhou

Am J Physiol Cell Physiol. 2023 Oct 1; 325(4): C833–C848. Published online 2023 Aug 29. doi: 10.1152/ajpcell.00249.2023

PMCID:: PMC10635659

Abstract Article

Select item 105658766.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 103459637.

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2–Bispecific Antibody for Combination Cancer Therapy

Amr El Zawily, Frederick S. Vizeacoumar, Renuka Dahiya, Sara L. Banerjee, Kalpana K. Bhanumathy, Hussain Elhasasna, Glinton Hanover, Jessica C. Sharpe, Malkon G. Sanchez, Paul Greidanus, R. Greg Stacey, Kyung-Mee Moon, Ilya Alexandrov, Juha P. Himanen, Dimitar B. Nikolov, Humphrey Fonge, Aaron P. White, Leonard J. Foster, Bingcheng Wang, Behzad M. Toosi, Nicolas Bisson, Tajib A. Mirzabekov, Franco J. Vizeacoumar, Andrew Freywald

Clin Cancer Res. 2023 Jul 14; 29(14): 2686–2701. Published online 2023 Mar 28. doi: 10.1158/1078-0432.CCR-22-2535

PMCID:: PMC10345963

Abstract Article PDF–13M

Select item 102066228.

DEPDC1B is involved in the proliferation, metastasis, cell cycle arrest and apoptosis of colon cancer cells by regulating NUP37

Hui Xiong, Yun Li, Manhua Liu

Mol Med Rep. 2023 Jun; 27(6): 126. Published online 2023 May 16. doi: 10.3892/mmr.2023.13013

PMCID:: PMC10206622

Abstract Article PDF–19M

Select item 97694489.

DEPDC1B promotes colorectal cancer via facilitating cell proliferation and migration while inhibiting apoptosis

Fei Han, Chao Cheng, Qianqian Xu, Jisong Chen, Zhaohui Yang, Jun Liu

Cell Cycle. 2023; 22(1): 131–143. Published online 2022 Aug 25. doi: 10.1080/15384101.2022.2110439

PMCID:: PMC9769448

Abstract Article PDF–4.5M

Select item 917141110.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 911973611.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 905883612.

The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside

Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang

J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009

PMCID:: PMC9058836

Abstract Article PDF–2.9M

Select item 898190413.

DEPDC1B Promotes Melanoma Angiogenesis and Metastasis through Sequestration of Ubiquitin Ligase CDC16 to Stabilize Secreted SCUBE3

Feng Hu, Ki On Fong, May Pui Lai Cheung, Jessica Aijia Liu, Rui Liang, Tsz Wai Li, Rakesh Sharma, Philip Pun‐Ching IP, Xintao Yang, Martin Cheung

Adv Sci (Weinh) 2022 Apr; 9(10): 2105226. Published online 2022 Jan 27. doi: 10.1002/advs.202105226

PMCID:: PMC8981904

Abstract Article PDF–13M

Select item 880596614.

DEP domain containing 1B (DEPDC1B) exerts the tumor promoter in hepatocellular carcinoma through activating p53 signaling pathway via kinesin family member 23 (KIF23)

Enhua Shen, Jingzhi Zhang, Yujuan Lu

Bioengineered. 2022; 13(1): 1103–1114. Published online 2022 Jan 5. doi: 10.1080/21655979.2021.2017629

PMCID:: PMC8805966

Abstract Article PDF–3.7M

Select item 843691515.

Overexpressed DEPDC1B contributes to the progression of hepatocellular carcinoma by CDK1

Xiao-Wei Dang, Qi Pan, Zhen-Hai Lin, Hao-Hao Wang, Lu-Hao Li, Lin Li, Dong-Qi Shen, Pei-Ju Wang

Aging (Albany NY) 2021 Aug 31; 13(16): 20094–20115. Published online 2021 May 25. doi: 10.18632/aging.203016

PMCID:: PMC8436915

Abstract Article PDF–3.0M

Select item 832477716.

DEPDC1B regulates the progression of human chordoma through UBE2T-mediated ubiquitination of BIRC5

Liang Wang, Liang Tang, Ruijun Xu, Junpeng Ma, Kaibing Tian, Yanbin Liu, Yanghu Lu, Zhen Wu, Xiaodong Zhu

Cell Death Dis. 2021 Aug; 12(8): 753. Published online 2021 Jul 30. doi: 10.1038/s41419-021-04026-7

Correction in:: Cell Death Dis. 2022 Jul; 13(7): 631.

PMCID:: PMC8324777

Abstract Article PDF–3.6M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 808827418.

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch

Agnieszka T. Kawashima, Cassandra Wong, Gema Lordén, Charles C. King, Pablo Lara-Gonzalez, Arshad Desai, Anne-Claude Gingras, Alexandra C. Newton

Mol Cell Biol. 2021 Mar; 41(3): e00333-20. Prepublished online 2021 Jan 4. Published online 2021 Feb 23. doi: 10.1128/MCB.00333-20

PMCID:: PMC8088274

Abstract Article PDF–3.1M

Select item 803721119.

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective

Veronique Jonckheere, Petra Van Damme

Int J Mol Sci. 2021 Apr; 22(7): 3690. Published online 2021 Apr 1. doi: 10.3390/ijms22073690

PMCID:: PMC8037211

Abstract Article PDF–6.5M

Select item 767206220.

DEPDC1B is a tumor promotor in development of bladder cancer through targeting SHC1

Chin-Hui Lai, Kexin Xu, Jianhua Zhou, Mingrui Wang, Weiyu Zhang, Xianhui Liu, Jie Xiong, Tao Wang, Qi Wang, Huanrui Wang, Tao Xu, Hao Hu

Cell Death Dis. 2020 Nov; 11(11): 986. Published online 2020 Nov 17. doi: 10.1038/s41419-020-03190-6

PMCID:: PMC7672062

Abstract Article PDF–2.4M

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