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Select item 107170491.

Hypoxia suppresses Kv 2.1 channel expression through endogenous 15-hydroxyeicosatetraenoic acid in rat pulmonary artery

Lei Guo, Zhaoping Qiu, Lei Zhang, Shuo Chen, Daling Zhu

J Physiol Sci. 2010 Sep; 60(5): 373–381. Published online 2010 Aug 3. doi: 10.1007/s12576-010-0105-z

PMCID:: PMC10717049

Abstract Article PDF–738K

Select item 104169092.

Kv2.1 Channels Prevent Vasomotion and Safeguard Myogenic Reactivity in Rat Small Superior Cerebellar Arteries

Kristina Här, Natalia N. Lysenko, Daniela Dimitrova, Torsten Schlüter, Olga Zavaritskaya, Andrej G. Kamkin, Mitko Mladenov, Olaf Grisk, Ralf Köhler, Hristo Gagov, Rudolf Schubert

Cells. 2023 Aug; 12(15): 1989. Published online 2023 Aug 2. doi: 10.3390/cells12151989

PMCID:: PMC10416909

Abstract Article PDF–1.2M

Select item 80469733.

Hydrogen sulfide regulates hippocampal neuron excitability via S-sulfhydration of Kv2.1

Mark L. Dallas, Moza M. Al-Owais, Nishani T. Hettiarachchi, Matthew Scott Vandiver, Heledd H. Jarosz-Griffiths, Jason L. Scragg, John P. Boyle, Derek Steele, Chris Peers

Sci Rep. 2021; 11: 8194. Published online 2021 Apr 14. doi: 10.1038/s41598-021-87646-5

PMCID:: PMC8046973

Abstract Article PDF–1.4M

Select item 78638784.

Site-specific contacts enable distinct modes of TRPV1 regulation by the potassium channel Kvβ1 subunit

Yuanyuan Wang, Xiaoyi Mo, Conghui Ping, Qian Huang, Hao Zhang, Chang Xie, Bo Zhong, Dongdong Li, Jing Yao

J Biol Chem. 2020 Dec 11; 295(50): 17337–17348. Published online 2020 Oct 15. doi: 10.1074/jbc.RA120.015605

PMCID:: PMC7863878

Abstract Article PDF–3.4M

Select item 77654285.

Tyrosine Phosphorylation of the K_v2.1 Channel Contributes to Injury in Brain Ischemia

Min-Young Song, Ji Yeon Hwang, Eun Ji Bae, Saesbyeol Kim, Hye-Min Kang, Yong Jun Kim, Chan Park, Kang-Sik Park

Int J Mol Sci. 2020 Dec; 21(24): 9538. Published online 2020 Dec 15. doi: 10.3390/ijms21249538

PMCID:: PMC7765428

Abstract Article PDF–1.6M

Select item 77259226.

Epilepsy and neurobehavioral abnormalities in mice with a dominant-negative KCNB1 pathogenic variant

Nicole A. Hawkins, Sunita N Misra, Manuel Jurado, Seok Kyu Kang, Nicholas C. Vierra, Kimberly Nguyen, Lisa Wren, Alfred L. George, Jr., James S. Trimmer, Jennifer A. Kearney

Neurobiol Dis. Author manuscript; available in PMC 2021 Jan 1.

Published in final edited form as: Neurobiol Dis. 2021 Jan; 147: 105141. Published online 2020 Oct 22. doi: 10.1016/j.nbd.2020.105141

PMCID:: PMC7725922

Abstract Article PDF–1.6M

Select item 67404847.

Zoe A. McCrossan, Anthony Lewis, Gianina Panaghie, Peter N. Jordan, David J. Christini, Daniel J. Lerner, Geoffrey W. Abbott

J Neurosci. 2003 Sep 3; 23(22): 8077–8091. doi: 10.1523/JNEUROSCI.23-22-08077.2003

PMCID:: PMC6740484

Abstract Article PDF–882K

Select item 67256548.

Calcium- and Metabolic State-Dependent Modulation of the Voltage-Dependent Kv2.1 Channel Regulates Neuronal Excitability in Response to Ischemia

Hiroaki Misonou, Durga P. Mohapatra, Milena Menegola, James S. Trimmer

J Neurosci. 2005 Nov 30; 25(48): 11184–11193. doi: 10.1523/JNEUROSCI.3370-05.2005

PMCID:: PMC6725654

Abstract Article PDF–462K

Select item 67057469.

Trafficking of Kv2.1 Channels to the Axon Initial Segment by a Novel Nonconventional Secretory Pathway

Camilla Stampe Jensen, Shoji Watanabe, Jeroen Ingrid Stas, Jessica Klaphaak, Ayaka Yamane, Nicole Schmitt, Søren-Peter Olesen, James S. Trimmer, Hanne Borger Rasmussen, Hiroaki Misonou

J Neurosci. 2017 Nov 29; 37(48): 11523–11536. doi: 10.1523/JNEUROSCI.3510-16.2017

PMCID:: PMC6705746

Abstract Article PDF–3.8M

Select item 668176010.

Defining the Kv2.1–syntaxin molecular interaction identifies a first-in-class small molecule neuroprotectant

Chung-Yang Yeh, Zhaofeng Ye, Aubin Moutal, Shivani Gaur, Amanda M. Henton, Stylianos Kouvaros, Jami L. Saloman, Karen A. Hartnett-Scott, Thanos Tzounopoulos, Rajesh Khanna, Elias Aizenman, Carlos J. Camacho

Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15696–15705. Published online 2019 Jul 15. doi: 10.1073/pnas.1903401116

PMCID:: PMC6681760

Abstract Article PDF–2.4M

Select item 667445511.

Kv2.1 Potassium Channels Are Retained within Dynamic Cell Surface Microdomains That Are Defined by a Perimeter Fence

Kristen M. S. O'Connell, Annah S. Rolig, Jennifer D. Whitesell, Michael M. Tamkun

J Neurosci. 2006 Sep 20; 26(38): 9609–9618. doi: 10.1523/JNEUROSCI.1825-06.2006

PMCID:: PMC6674455

Abstract Article PDF–523K

Select item 667443012.

The Kv2.1 C Terminus Can Autonomously Transfer Kv2.1-Like Phosphorylation-Dependent Localization, Voltage-Dependent Gating, and Muscarinic Modulation to Diverse Kv Channels

Durga P. Mohapatra, James S. Trimmer

J Neurosci. 2006 Jan 11; 26(2): 685–695. doi: 10.1523/JNEUROSCI.4620-05.2006

PMCID:: PMC6674430

Abstract Article PDF–646K

Select item 667374713.

K⁺ Channel Facilitation of Exocytosis by Dynamic Interaction with Syntaxin

Dafna Singer-Lahat, Anton Sheinin, Dodo Chikvashvili, Sharon Tsuk, Dafna Greitzer, Reut Friedrich, Lori Feinshreiber, Uri Ashery, Morris Benveniste, Edwin S. Levitan, Ilana Lotan

J Neurosci. 2007 Feb 14; 27(7): 1651–1658. doi: 10.1523/JNEUROSCI.4006-06.2007

PMCID:: PMC6673747

Abstract Article PDF–390K

Select item 657672314.

Contrasting immunohistochemical localizations in rat brain of two novel K+ channels of the Shab subfamily

PM Hwang, M Fotuhi, DS Bredt, AM Cunningham, SH Snyder

J Neurosci. 1993 Apr 1; 13(4): 1569–1576. doi: 10.1523/JNEUROSCI.13-04-01569.1993

PMCID:: PMC6576723

Abstract PDF–2.4M

Select item 657561015.

Distinct spatial and temporal expression patterns of K+ channel mRNAs from different subfamilies

JA Drewe, S Verma, G Frech, RH Joho

J Neurosci. 1992 Feb 1; 12(2): 538–548. doi: 10.1523/JNEUROSCI.12-02-00538.1992

PMCID:: PMC6575610

Abstract PDF–2.1M

Select item 649793416.

Clustered Kv2.1 decreases dopamine transporter activity and internalization

Joseph J. Lebowitz, Jose A. Pino, Phillip M. Mackie, Min Lin, Cheyenne Hurst, Keeley Divita, Anthony T. Collins, Dimitri N. Koutzoumis, Gonzalo E. Torres, Habibeh Khoshbouei

J Biol Chem. 2019 Apr 26; 294(17): 6957–6971. Published online 2019 Mar 1. doi: 10.1074/jbc.RA119.007441

PMCID:: PMC6497934

Abstract Article PDF–5.9M

Select item 619325417.

Molecular Neuroprotection Induced by Zinc-Dependent Expression of Hepatitis C–Derived Protein NS5A Targeting Kv2.1 Potassium Channels

Jason A. Justice, Daniel T. Manjooran, Chung-Yang Yeh, Karen A. Hartnett-Scott, Anthony J. Schulien, Gabrielle J. Kosobucki, Shalom Mammen, Michael J. Palladino, Elias Aizenman

J Pharmacol Exp Ther. 2018 Nov; 367(2): 348–355. Published online 2018 Nov. doi: 10.1124/jpet.118.252338

PMCID:: PMC6193254

Abstract Article PDF–552K

Select item 607774618.

Kv2 potassium channels form endoplasmic reticulum/plasma membrane junctions via interaction with VAPA and VAPB

Ben Johnson, Ashley N. Leek, Laura Solé, Emily E. Maverick, Tim P. Levine, Michael M. Tamkun

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): E7331–E7340. Published online 2018 Jun 25. doi: 10.1073/pnas.1805757115

PMCID:: PMC6077746

Abstract Article PDF–1.9M

Select item 593683219.

K_v2.1 clusters on β-cell plasma membrane act as reservoirs that replenish pools of newcomer insulin granule through their interaction with syntaxin-3

Dafna Greitzer-Antes, Li Xie, Tairan Qin, Huanli Xie, Dan Zhu, Subhankar Dolai, Tao Liang, Fei Kang, Alexandre B. Hardy, Yan He, Youhou Kang, Herbert Y. Gaisano

J Biol Chem. 2018 May 4; 293(18): 6893–6904. Published online 2018 Mar 16. doi: 10.1074/jbc.RA118.002703

PMCID:: PMC5936832

Abstract Article PDF–2.3M

Select item 571024220.

Neurodevelopmental Disorders Caused by De Novo Variants in KCNB1 Genotypes and Phenotypes

Carolien G. F. de Kovel, Steffen Syrbe, Eva H. Brilstra, Nienke Verbeek, Bronwyn Kerr, Holly Dubbs, Allan Bayat, Sonal Desai, Sakkubai Naidu, Siddharth Srivastava, Hande Cagaylan, Uluc Yis, Carol Saunders, Martin Rook, Susanna Plugge, Hiltrud Muhle, Zaid Afawi, Karl-Martin Klein, Vijayakumar Jayaraman, Ramakrishnan Rajagopalan, Ethan Goldberg, Eric Marsh, Sudha Kessler, Christina Bergqvist, Laura K. Conlin, Bryan L. Krok, Isabelle Thiffault, Manuela Pendziwiat, Ingo Helbig, Tilman Polster, Ingo Borggraefe, Johannes R. Lemke, Marie-José van den Boogaardt, Rikke S. Møller, Bobby P. C. Koeleman

JAMA Neurol. 2017 Oct; 74(10): 1228–1236. Prepublished online 2017 Aug 14. Published online 2017 Oct 9. doi: 10.1001/jamaneurol.2017.1714

PMCID:: PMC5710242

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