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Items: 1 to 20 of 65

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Catechol-O-Methyltransferase Loss Drives Cell-Specific Nociceptive Signaling via the Enteric COMT/miR-155/TNF-α Axis
QiQi Zhou, Liuqing Yang, Meghan L. Verne, Benjamin B. Zhang, Jeremy Fields, George Nicholas Verne
Gastroenterology. Author manuscript; available in PMC 2024 Apr 1.
Published in final edited form as: Gastroenterology. 2023 Apr; 164(4): 630–641.e34. Published online 2023 Jan 6. doi: 10.1053/j.gastro.2022.12.041
PMCID:
PMC10038873
AbstractArticlePDF–1.5M
3.
The impact of pimavanserin on psychotic phenotypes and tau phosphorylation in the P301L/COMT– and rTg(P301L)4510 mouse models of Alzheimer's disease
Heidy Jimenez, Leslie Adrien, Adam Wolin, John Eun, Eric H. Chang, Ethan S. Burstein, Jesus Gomar, Peter Davies, Jeremy Koppel
Alzheimers Dement (N Y) 2022; 8(1): e12247. Published online 2022 Feb 1. doi: 10.1002/trc2.12247
PMCID:
PMC8804623
AbstractArticlePDF–913K
4.
Distinct roles of androgen receptor, estrogen receptor alpha, and BCL6 in the establishment of sex-biased DNA methylation in mouse liver
Najla AlOgayil, Klara Bauermeister, Jose Hector Galvez, Varun S. Venkatesh, Qinwei Kim-wee Zhuang, Matthew L. Chang, Rachel A. Davey, Jeffrey D. Zajac, Kinuyo Ida, Akihide Kamiya, Teruko Taketo, Guillaume Bourque, Anna K. Naumova
Sci Rep. 2021; 11: 13766. Published online 2021 Jul 2. doi: 10.1038/s41598-021-93216-6
Correction in:
Sci Rep. 2021; 11: 22975.
PMCID:
PMC8253761
AbstractArticlePDF–7.9M
5.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
6.
Increased tau phosphorylation follows impeded dopamine clearance in a P301L and novel P301L/COMT-deleted (DM) tau mouse model
Jeremy Koppel, Heidy Jimenez, Leslie Adrien, Eric H. Chang, Anil K. Malhotra, Peter Davies
J Neurochem. Author manuscript; available in PMC 2019 Sep 24.
Published in final edited form as: J Neurochem. 2019 Jan; 148(1): 127–135. Published online 2018 Nov 12. doi: 10.1111/jnc.14593
PMCID:
PMC6758923
AbstractArticlePDF–826K
7.
Site-Specific Role of Catechol-O-Methyltransferase in Dopamine Overflow within Prefrontal Cortex and Dorsal Striatum
Leonid Yavich, Markus M. Forsberg, Maria Karayiorgou, Joseph A. Gogos, Pekka T. Männistö
J Neurosci. 2007 Sep 19; 27(38): 10196–10209. doi: 10.1523/JNEUROSCI.0665-07.2007
PMCID:
PMC6672678
AbstractArticlePDF–300K
8.
Heritable Differences in Catecholamine Signaling Modulate Susceptibility to Trauma and Response to Methylphenidate Treatment: Relevance for PTSD
Jessica Deslauriers, Mate Toth, Xianjin Zhou, Victoria B. Risbrough
Front Behav Neurosci. 2019; 13: 111. Published online 2019 May 17. doi: 10.3389/fnbeh.2019.00111
PMCID:
PMC6534065
AbstractArticlePDF–2.0M
9.
Loss of placental growth factor ameliorates maternal hypertension and preeclampsia in mice
Jacqueline G. Parchem, Keizo Kanasaki, Megumi Kanasaki, Hikaru Sugimoto, Liang Xie, Yuki Hamano, Soo Bong Lee, Vincent H. Gattone, Samuel Parry, Jerome F. Strauss, Vesna D. Garovic, Thomas F. McElrath, Karen H. Lu, Baha M. Sibai, Valerie S. LeBleu, Peter Carmeliet, Raghu Kalluri
J Clin Invest. 2018 Nov 1; 128(11): 5008–5017. Published online 2018 Oct 8. doi: 10.1172/JCI99026
PMCID:
PMC6205389
AbstractArticlePDF–8.3M
10.
Apolipoprotein A1 mimetic peptide ATI-5261 reverses arterial stiffness at late pregnancy and early postpartum in a COMT−/− mouse model of preeclampsia
Shutan Liao, Hao Wu, Ruiying Chen
Clin Hypertens. 2018; 24: 11. Published online 2018 Sep 15. doi: 10.1186/s40885-018-0097-1
PMCID:
PMC6138905
AbstractArticlePDF–1.0M
11.
Adolescence is the starting point of sex-dichotomous COMT genetic effects
S Sannino, M C Padula, F Managò, M Schaer, M Schneider, M Armando, E Scariati, F Sloan-Bena, M Mereu, M Pontillo, S Vicari, G Contarini, C Chiabrera, M Pagani, A Gozzi, S Eliez, F Papaleo
Transl Psychiatry. 2017 May; 7(5): e1141. Published online 2017 May 30. doi: 10.1038/tp.2017.109
PMCID:
PMC5584523
AbstractArticlePDF–1.5M
12.
Attentional Control in Adolescent Mice Assessed with a Modified Five Choice Serial Reaction Time Task
Mariasole Ciampoli, Gabriella Contarini, Maddalena Mereu, Francesco Papaleo
Sci Rep. 2017; 7: 9936. Published online 2017 Aug 30. doi: 10.1038/s41598-017-10112-8
PMCID:
PMC5577211
AbstractArticlePDF–4.3M
13.
Deficiency in catechol-o-methyltransferase is linked to a disruption of glucose homeostasis in mice
Megumi Kanasaki, Swayam Prakash Srivastava, Fan Yang, Ling Xu, Sumiyo Kudoh, Munehiro Kitada, Norikazu Ueki, Hyoh Kim, Jinpeng Li, Satoru Takeda, Keizo Kanasaki, Daisuke Koya
Sci Rep. 2017; 7: 7927. Published online 2017 Aug 11. doi: 10.1038/s41598-017-08513-w
PMCID:
PMC5554180
AbstractArticlePDF–4.5M
14.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
15.
Genotype-Dependent Effects of COMT Inhibition on Cognitive Function in a Highly Specific, Novel Mouse Model of Altered COMT Activity
Chris Barkus, Clio Korn, Katharina Stumpenhorst, Linda M Laatikainen, Dominic Ballard, Sheena Lee, Trevor Sharp, Paul J Harrison, David M Bannerman, Daniel R Weinberger, Jingshan Chen, Elizabeth M Tunbridge
Neuropsychopharmacology. 2016 Dec; 41(13): 3060–3069. Prepublished online 2016 Jul 8. Published online 2016 Aug 10. doi: 10.1038/npp.2016.119
PMCID:
PMC5101554
AbstractArticlePDF–369K
16.
Epistatic interaction between COMT and DTNBP1 modulates prefrontal function in mice and in humans
F Papaleo, MC Burdick, JH Callicott, DR Weinberger
Mol Psychiatry. Author manuscript; available in PMC 2016 Apr 26.
Published in final edited form as: Mol Psychiatry. 2014 Mar; 19(3): 311–316. Published online 2013 Oct 22. doi: 10.1038/mp.2013.133
PMCID:
PMC4845721
AbstractArticlePDF–1003K
17.
Ranbp1, Deleted in DiGeorge/22q11.2 Deletion Syndrome, is a Microcephaly Gene That Selectively Disrupts Layer 2/3 Cortical Projection Neuron Generation
Elizabeth M. Paronett, Daniel W. Meechan, Beverly A. Karpinski, Anthony-Samuel LaMantia, Thomas M. Maynard
Cereb Cortex. 2015 Oct; 25(10): 3977–3993. Published online 2014 Dec 1. doi: 10.1093/cercor/bhu285
PMCID:
PMC4585528
AbstractArticlePDF–2.0M
18.
Molecular genetic mechanisms of allelic specific regulation of murine Comt expression
Samantha K. Segall, Svetlana A. Shabalina, Carolina B. Meloto, Xia Wen, Danielle Cunningham, Lisa M. Tarantino, Tim Wiltshire, Josée Gauthier, Sarasa Tohyama, Loren J. Martin, Jeffrey S. Mogil, Luda Diatchenko
Pain. 2015 Oct; 156(10): 1965–1977. Published online 2015 Jun 9. doi: 10.1097/j.pain.0000000000000258
PMCID:
PMC4579042
AbstractArticlePDF–1000K
19.
COMT Genetic Reduction Produces Sexually Divergent Effects on Cortical Anatomy and Working Memory in Mice and Humans
Sara Sannino, Alessandro Gozzi, Antonio Cerasa, Fabrizio Piras, Diego Scheggia, Francesca Managò, Mario Damiano, Alberto Galbusera, Lucy C. Erickson, Davide De Pietri Tonelli, Angelo Bifone, Sotirios A. Tsaftaris, Carlo Caltagirone, Daniel R. Weinberger, Gianfranco Spalletta, Francesco Papaleo
Cereb Cortex. 2015 Sep; 25(9): 2529–2541. Published online 2014 Mar 21. doi: 10.1093/cercor/bhu053
PMCID:
PMC4542698
AbstractArticlePDF–1010K
20.
A high resolution spatiotemporal atlas of gene expression of the developing mouse brain
Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones
Neuron. Author manuscript; available in PMC 2015 Jul 16.
Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033
PMCID:
PMC4319559
AbstractArticlePDF–3.0M

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