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Select item 106617501.

Unconventional roles of chromatin remodelers and long non-coding RNAs in cell division

Yuri Prozzillo, Maria Virginia Santopietro, Giovanni Messina, Patrizio Dimitri

Cell Mol Life Sci. 2023 Dec; 80(12): 365. Published online 2023 Nov 20. doi: 10.1007/s00018-023-04949-8

PMCID:: PMC10661750

Abstract Article PDF–1.3M

Select item 106537662.

Role of gut commensal bacteria in juvenile developmental growth of the host: insights from Drosophila studies

Hyun Myoung Yun, Seogang Hyun

Anim Cells Syst (Seoul) 2023; 27(1): 329–339. Published online 2023 Nov 15. doi: 10.1080/19768354.2023.2282726

PMCID:: PMC10653766

Abstract Article PDF–1.1M

Select item 106037633.

Targeted RNAi screen identifies transcriptional mechanisms that prevent premature degeneration of adult photoreceptors

Spencer E. Escobedo, Sarah E. McGovern, Juan P. Jauregui-Lozano, Sarah C. Stanhope, Paul Anik, Kratika Singhal, Ryan DeBernardis, Vikki M. Weake

Front Epigenet Epigenom. Author manuscript; available in PMC 2023 Oct 27.

Published in final edited form as: Front Epigenet Epigenom. 2023; 1: 1187980. Published online 2023 May 5. doi: 10.3389/freae.2023.1187980

PMCID:: PMC10603763

Abstract Article PDF–1.3M

Select item 103724084.

Dissecting morphogenetic apoptosis through a genetic screen in Drosophila

Audrey Barbaste, Sonia Schott, Corinne Benassayag, Magali Suzanne

Life Sci Alliance. 2023 Oct; 6(10): e202301967. Published online 2023 Jul 26. doi: 10.26508/lsa.202301967

PMCID:: PMC10372408

Abstract Article PDF–4.5M

Select item 102162355.

Knockdown of DOM/Tip60 Complex Subunits Impairs Male Meiosis of Drosophila melanogaster

Yuri Prozzillo, Gaia Fattorini, Diego Ferreri, Manuela Leo, Patrizio Dimitri, Giovanni Messina

Cells. 2023 May; 12(10): 1348. Published online 2023 May 9. doi: 10.3390/cells12101348

PMCID:: PMC10216235

Abstract Article PDF–8.0M

Select item 100723036.

Tip60's Novel RNA-Binding Function Modulates Alternative Splicing of Pre-mRNA Targets Implicated in Alzheimer's Disease

Akanksha Bhatnagar, Keegan Krick, Bhanu Chandra Karisetty, Ellen M. Armour, Elizabeth A. Heller, Felice Elefant

J Neurosci. 2023 Mar 29; 43(13): 2398–2423. doi: 10.1523/JNEUROSCI.2331-22.2023

PMCID:: PMC10072303

Abstract Article PDF–6.1M

Select item 98941847.

Acetyl-CoA-mediated autoacetylation of fatty acid synthase as a metabolic switch of de novo lipogenesis in Drosophila

Ting Miao, Jinoh Kim, Ping Kang, Hideji Fujiwara, Fong-Fu Hsu, Hua Bai

Proc Natl Acad Sci U S A. 2022 Dec 6; 119(49): e2212220119. Published online 2022 Dec 2. doi: 10.1073/pnas.2212220119

PMCID:: PMC9894184

Abstract Article PDF–3.8M

Select item 94511598.

Variant Polycomb complexes in Drosophila consistent with ancient functional diversity

Hyuckjoon Kang, Janel R. Cabrera, Barry M. Zee, Heather A. Kang, Jenny Marie Jobe, Maeve B. Hegarty, Aurelie E. Barry, Alexander Glotov, Yuri B. Schwartz, Mitzi I. Kuroda

Sci Adv. 2022 Sep; 8(36): eadd0103. Published online 2022 Sep 7. doi: 10.1126/sciadv.add0103

PMCID:: PMC9451159

Abstract Article PDF–1.3M

Select item 93511379.

Evolutionary conserved relocation of chromatin remodeling complexes to the mitotic apparatus

Giovanni Messina, Yuri Prozzillo, Francesca Delle Monache, Maria Virginia Santopietro, Patrizio Dimitri

BMC Biol. 2022; 20: 172. Published online 2022 Aug 3. doi: 10.1186/s12915-022-01365-5

PMCID:: PMC9351137

Abstract Article PDF–10M

Select item 933649510.

Chromatin and transcriptomic profiling uncover dysregulation of the Tip60 HAT/HDAC2 epigenomic landscape in the neurodegenerative brain

Mariah Beaver, Bhanu Chandra Karisetty, Haolin Zhang, Akanksha Bhatnagar, Ellen Armour, Visha Parmar, Reshma Brown, Merry Xiang, Felice Elefant

Epigenetics. 2022; 17(7): 786–807. Published online 2021 Aug 9. doi: 10.1080/15592294.2021.1959742

PMCID:: PMC9336495

Abstract Article PDF–3.5M

Select item 906500111.

Pantothenate kinase 2 interacts with PINK1 to regulate mitochondrial quality control via acetyl-CoA metabolism

Yunpeng Huang, Zhihui Wan, Yinglu Tang, Junxuan Xu, Bretton Laboret, Sree Nallamothu, Chenyu Yang, Boxiang Liu, Rongze Olivia Lu, Bingwei Lu, Juan Feng, Jing Cao, Susan Hayflick, Zhihao Wu, Bing Zhou

Nat Commun. 2022; 13: 2412. Published online 2022 May 3. doi: 10.1038/s41467-022-30178-x

PMCID:: PMC9065001

Abstract Article PDF–5.6M

Select item 866448612.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 838416913.

A genetic screen in Drosophila uncovers the multifaceted properties of the NUP98-HOXA9 oncogene

Gwenaëlle Gavory, Caroline Baril, Gino Laberge, Gawa Bidla, Surapong Koonpaew, Thomas Sonea, Guy Sauvageau, Marc Therrien

PLoS Genet. 2021 Aug; 17(8): e1009730. Published online 2021 Aug 12. doi: 10.1371/journal.pgen.1009730

PMCID:: PMC8384169

Abstract Article PDF–5.3M

Select item 836357014.

Microbiota-derived acetate activates intestinal innate immunity via the Tip60 histone acetyltransferase complex

Bat-Erdene Jugder, Layla Kamareddine, Paula I Watnick

Immunity. Author manuscript; available in PMC 2022 Aug 10.

Published in final edited form as: Immunity. 2021 Aug 10; 54(8): 1683–1697.e3. Published online 2021 Jun 8. doi: 10.1016/j.immuni.2021.05.017

PMCID:: PMC8363570

Abstract Article PDF–3.4M

Select item 812369215.

In Vivo Silencing of Genes Coding for dTip60 Chromatin Remodeling Complex Subunits Affects Polytene Chromosome Organization and Proper Development in Drosophila melanogaster

Yuri Prozzillo, Stefano Cuticone, Diego Ferreri, Gaia Fattorini, Giovanni Messina, Patrizio Dimitri

Int J Mol Sci. 2021 May; 22(9): 4525. Published online 2021 Apr 26. doi: 10.3390/ijms22094525

PMCID:: PMC8123692

Abstract Article PDF–3.5M

Select item 799218716.

Epigenetic Regulation of Drosophila Germline Stem Cell Maintenance and Differentiation

Velinda Vidaurre, Xin Chen

Dev Biol. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Dev Biol. 2021 May; 473: 105–118. Published online 2021 Feb 18. doi: 10.1016/j.ydbio.2021.02.003

PMCID:: PMC7992187

Abstract Article PDF–1.0M

Select item 773720217.

Tip60 protects against amyloid-β-induced transcriptomic alterations via different modes of action in early versus late stages of neurodegeneration

Haolin Zhang, Bhanu Chandra Karisetty, Akanksha Bhatnagar, Ellen M. Armour, Mariah Beaver, Tiffany V. Roach, Sina Mortazavi, Shreya Mandloi, Felice Elefant

Mol Cell Neurosci. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Mol Cell Neurosci. 2020 Dec; 109: 103570. Published online 2020 Nov 4. doi: 10.1016/j.mcn.2020.103570

PMCID:: PMC7737202

Abstract Article PDF–2.7M

Select item 761443018.

Transcriptional memory of dFOXO activation in youth curtails later-life mortality through chromatin remodelling and Xbp1

Guillermo Martínez Corrales, Mengjia Li, Tatiana Svermova, Alex Goncalves, Diana Voicu, Adam J. Dobson, Tony D. Southall, Nazif Alic

Nat Aging. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: Nat Aging. 2022 Dec; 2: 1176–1190. Published online 2022 Dec 1. doi: 10.1038/s43587-022-00312-x

PMCID:: PMC7614430

Abstract Article PDF–5.0M

Select item 758844519.

Disruption of Tip60 HAT mediated neural histone acetylation homeostasis is an early common event in neurodegenerative diseases

Mariah Beaver, Akanksha Bhatnagar, Priyalakshmi Panikker, Haolin Zhang, Renee Snook, Visha Parmar, Gayathri Vijayakumar, Niteesha Betini, Sunya Akhter, Felice Elefant

Sci Rep. 2020; 10: 18265. Published online 2020 Oct 26. doi: 10.1038/s41598-020-75035-3