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Select item 105847551.

Insights into human kidney function from the study of Drosophila

Sybille Koehler, Tobias B. Huber

Pediatr Nephrol. 2023; 38(12): 3875–3887. Published online 2023 May 12. doi: 10.1007/s00467-023-05996-w

PMCID:: PMC10584755

Abstract Article PDF–1.2M

Select item 105237612.

Analysis of asymptomatic Drosophila models for ALS and SMA reveals convergent impact on functional protein complexes linked to neuro-muscular degeneration

Marina L. Garcia-Vaquero, Marjorie Heim, Barbara Flix, Marcelo Pereira, Lucile Palin, Tânia M. Marques, Francisco R. Pinto, Javier de Las Rivas, Aaron Voigt, Florence Besse, Margarida Gama-Carvalho

BMC Genomics. 2023; 24: 576. Published online 2023 Sep 27. doi: 10.1186/s12864-023-09562-4

PMCID:: PMC10523761

Abstract Article PDF–3.2M

Select item 105014493.

Fusion pore dynamics of large secretory vesicles define a distinct mechanism of exocytosis

Tom Biton, Nadav Scher, Shari Carmon, Yael Elbaz-Alon, Eyal D. Schejter, Ben-Zion Shilo, Ori Avinoam

J Cell Biol. 2023 Nov 6; 222(11): e202302112. Published online 2023 Sep 14. doi: 10.1083/jcb.202302112

PMCID:: PMC10501449

Abstract Article PDF–8.7M

Select item 101057364.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 100172665.

Systematic analysis of RhoGEF/GAP localizations uncovers regulators of mechanosensing and junction formation during epithelial cell division

Florencia di Pietro, Mariana Osswald, José M. De las Heras, Inês Cristo, Jesús López-Gay, Zhimin Wang, Stéphane Pelletier, Isabelle Gaugué, Adrien Leroy, Charlotte Martin, Eurico Morais-de-Sá, Yohanns Bellaïche

Curr Biol. 2023 Mar 13; 33(5): 858–874.e7. doi: 10.1016/j.cub.2023.01.028

PMCID:: PMC10017266

Abstract Article

Select item 88989026.

Using Drosophila Nephrocytes to Understand the Formation and Maintenance of the Podocyte Slit Diaphragm

Joyce van de Leemput, Pei Wen, Zhe Han

Front Cell Dev Biol. 2022; 10: 837828. Published online 2022 Feb 21. doi: 10.3389/fcell.2022.837828

PMCID:: PMC8898902

Abstract Article PDF–1018K

Select item 79276647.

RhoGAP19D inhibits Cdc42 laterally to control epithelial cell shape and prevent invasion

Weronika Fic, Rebecca Bastock, Francesco Raimondi, Erinn Los, Yoshiko Inoue, Jennifer L. Gallop, Robert B. Russell, Daniel St Johnston

J Cell Biol. 2021 Apr 5; 220(4): e202009116. Published online 2021 Mar 1. doi: 10.1083/jcb.202009116

PMCID:: PMC7927664

Abstract Article PDF–7.3M

Select item 69615788.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 60747929.

A Drosophila model system to assess the function of human monogenic podocyte mutations that cause nephrotic syndrome

Yulong Fu, Jun-yi Zhu, Adam Richman, Zhanzheng Zhao, Fujian Zhang, Patricio E. Ray, Zhe Han

Hum Mol Genet. 2017 Feb 15; 26(4): 768–780. Published online 2017 Feb 6. doi: 10.1093/hmg/ddw428

PMCID:: PMC6074792

Abstract Article PDF–1.4M

Select item 594031110.

Feedback inhibition of actin on Rho mediates content release from large secretory vesicles

Dagan Segal, Assaf Zaritsky, Eyal D. Schejter, Ben-Zion Shilo

J Cell Biol. 2018 May 7; 217(5): 1815–1826. doi: 10.1083/jcb.201711006

PMCID:: PMC5940311

Abstract Article PDF–2.5M

Select item 570780511.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900212.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 540772213.

Modeling Monogenic Human Nephrotic Syndrome in the Drosophila Garland Cell Nephrocyte

Tobias Hermle, Daniela A. Braun, Martin Helmstädter, Tobias B. Huber, Friedhelm Hildebrandt

J Am Soc Nephrol. 2017 May; 28(5): 1521–1533. Published online 2016 Dec 8. doi: 10.1681/ASN.2016050517

PMCID:: PMC5407722

Abstract Article

Select item 534099814.

A Luciferase-fragment Complementation Assay to Detect Lipid Droplet-associated Protein-Protein Interactions

Petra Kolkhof, Michael Werthebach, Anna van de Venn, Gereon Poschmann, Lili Chen, Michael Welte, Kai Stühler, Mathias Beller

Mol Cell Proteomics. 2017 Mar; 16(3): 329–345. Published online 2016 Dec 12. doi: 10.1074/mcp.M116.061499

PMCID:: PMC5340998

Abstract Article PDF–3.8M

Select item 509821815.

Functional screening of mammalian mechanosensitive genes using Drosophila RNAi library– Smarcd3/Bap60 is a mechanosensitive pro-inflammatory gene

Sandeep Kumar, In-hwan Jang, Chan Woo Kim, Dong-Won Kang, Won Jae Lee, Hanjoong Jo

Sci Rep. 2016; 6: 36461. Published online 2016 Nov 7. doi: 10.1038/srep36461

PMCID:: PMC5098218

Abstract Article PDF–1.6M

Select item 473800516.

Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes

Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Bezginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, W. Brent Derry, Elisabeth R. Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Data Brief. 2016 Mar; 6: 715–721. Published online 2015 Dec 12. doi: 10.1016/j.dib.2015.11.062

PMCID:: PMC4738005

Abstract Article PDF–205K

Select item 452833017.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832918.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 445871419.

The Drosophila Helicase Maleless (MLE) is Implicated in Functions Distinct From its Role in Dosage Compensation

Simona Cugusi, Satish Kallappagoudar, Huiping Ling, John C. Lucchesi

Mol Cell Proteomics. 2015 Jun; 14(6): 1478–1488. Published online 2015 Mar 16. doi: 10.1074/mcp.M114.040667

PMCID:: PMC4458714

Abstract Article PDF–625K

Select item 435288720.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Abstract Article PDF–1022K

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