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Items: 1 to 20 of 60

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
BACH1 promotes tissue necrosis and Mycobacterium tuberculosis susceptibility
Eduardo P. Amaral, Sivaranjani Namasivayam, Artur T. L. Queiroz, Eduardo Fukutani, Kerry L. Hilligan, Kate Aberman, Logan Fisher, Caio Cesar B. Bomfim, Keith Kauffman, Jay Buchanan, Leslie Santuo, Pedro Henrique Gazzinelli-Guimaraes, Diego L. Costa, Mariane Araujo Teixeira, Beatriz Barreto-Duarte, Clarissa Gurgel Rocha, Monique Freire Santana, Marcelo Cordeiro-Santos, Daniel L. Barber, Robert J. Wilkinson, Igor Kramnik, Kazuhiko Igarashi, Thomas Scriba, Katrin D. Mayer-Barber, Bruno B. Andrade, Alan Sher
Nat Microbiol. 2024; 9(1): 120–135. Published online 2023 Dec 8. doi: 10.1038/s41564-023-01523-7
PMCID:
PMC10769877
AbstractArticlePDF–17M
3.
BACH1 controls hepatic insulin signaling and glucose homeostasis in mice
Jiayu Jin, Yunquan He, Jieyu Guo, Qi Pan, Xiangxiang Wei, Chen Xu, Zhiyuan Qi, Qinhan Li, Siyu Ma, Jiayi Lin, Nan Jiang, Jinghua Ma, Xinhong Wang, Lindi Jiang, Qiurong Ding, Elena Osto, Xiuling Zhi, Dan Meng
Nat Commun. 2023; 14: 8428. Published online 2023 Dec 21. doi: 10.1038/s41467-023-44088-z
PMCID:
PMC10739811
AbstractArticlePDF–3.0M
4.
The placental vasculature is affected by changes in gene expression and glycogen-rich cells in a diet-induced obesity mouse model
Hui Zhao, Ronald J. Wong, David K. Stevenson
PLoS One. 2023; 18(11): e0294185. Published online 2023 Nov 10. doi: 10.1371/journal.pone.0294185
PMCID:
PMC10637699
AbstractArticlePDF–3.6M
5.
BACH1-Hemoxygenase-1 axis regulates cellular energetics and survival following sepsis
Lun Cai, Ali S. Arbab, Tae Jin Lee, Ashok Sharma, Bobby Thomas, Kazuhiko Igarashi, Raghavan Pillai Raju
Free Radic Biol Med. Author manuscript; available in PMC 2023 Sep 19.
Published in final edited form as: Free Radic Biol Med. 2022 Aug 1; 188: 134–145. Published online 2022 Jun 9. doi: 10.1016/j.freeradbiomed.2022.06.005
PMCID:
PMC10507736
AbstractArticlePDF–1.0M
6.
BACH1 deficiency prevents neointima formation and maintains the differentiated phenotype of vascular smooth muscle cells by regulating chromatin accessibility
Jieyu Guo, Jingjing Qiu, Mengping Jia, Qinhan Li, Xiangxiang Wei, Liliang Li, Qi Pan, Jiayu Jin, Fei Ge, Siyu Ma, Yunquan He, Jiayi Lin, Yongbo Li, Jinghua Ma, Nan Jiang, Xiuling Zhi, Lindi Jiang, Jianyi Zhang, Elena Osto, Qing Jing, Xinhong Wang, Dan Meng
Nucleic Acids Res. 2023 May 22; 51(9): 4284–4301. Published online 2023 Mar 2. doi: 10.1093/nar/gkad120
PMCID:
PMC10201429
AbstractArticlePDF–6.1M
7.
BACH1-induced ferroptosis drives lymphatic metastasis by repressing the biosynthesis of monounsaturated fatty acids
Xiufeng Xie, Lusong Tian, Yan Zhao, Fang Liu, Shuyang Dai, Xinglu Gu, Yuxin Ye, Lanping Zhou, Xinmiao Liu, Yulin Sun, Xiaohang Zhao
Cell Death Dis. 2023 Jan; 14(1): 48. Published online 2023 Jan 20. doi: 10.1038/s41419-023-05571-z
PMCID:
PMC9860034
AbstractArticlePDF–5.8M
8.
Counter Regulation of Spic by NF-κB and STAT Signaling Controls Inflammation and Iron Metabolism in Macrophages
Zahidul Alam, Samir Devalaraja, Minghong Li, Tsun Ki Jerrick To, Ian W. Folkert, Erick Mitchell-Velasquez, Mai T. Dang, Patricia Young, Christopher J. Wilbur, Michael A. Silverman, Xinyuan Li, Youhai H. Chen, Paul T. Hernandez, Aritra Bhattacharyya, Mallar Bhattacharya, Matthew H. Levine, Malay Haldar
Cell Rep. Author manuscript; available in PMC 2022 Mar 24.
Published in final edited form as: Cell Rep. 2020 Jun 30; 31(13): 107825. doi: 10.1016/j.celrep.2020.107825
PMCID:
PMC8944937
AbstractArticlePDF–2.0M
9.
Genetic BACH1 deficiency alters mitochondrial function and increases NLRP3 inflammasome activation in mouse macrophages
Pooja Pradhan, Vijith Vijayan, Karsten Cirksena, Falk F.R. Buettner, Kazuhiko Igarashi, Roberto Motterlini, Roberta Foresti, Stephan Immenschuh
Redox Biol. 2022 May; 51: 102265. Published online 2022 Feb 10. doi: 10.1016/j.redox.2022.102265
PMCID:
PMC8861416
AbstractArticlePDF–5.8M
10.
Bach1 derepression is neuroprotective in a mouse model of Parkinson’s disease
Manuj Ahuja, Navneet Ammal Kaidery, Otis C. Attucks, Erin McDade, Dmitry M. Hushpulian, Arsen Gaisin, Irina Gaisina, Young Hoon Ahn, Sergey Nikulin, Andrey Poloznikov, Irina Gazaryan, Masayuki Yamamoto, Mitsuyo Matsumoto, Kazuhiko Igarashi, Sudarshana M. Sharma, Bobby Thomas
Proc Natl Acad Sci U S A. 2021 Nov 9; 118(45): e2111643118. Published online 2021 Nov 5. doi: 10.1073/pnas.2111643118
Correction in:
Proc Natl Acad Sci U S A. 2021 Dec 28; 118(52): e2120610118.
Correction in:
Proc Natl Acad Sci U S A. 2024 Jul 2; 121(27): e2411303121.
PMCID:
PMC8694049
AbstractArticlePDF–1.6M
11.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
12.
BACH1 recruits NANOG and histone H3 lysine 4 methyltransferase MLL/SET1 complexes to regulate enhancer–promoter activity and maintains pluripotency
Cong Niu, Siqing Wang, Jieyu Guo, Xiangxiang Wei, Mengping Jia, Zhaoxiong Chen, Wenxuan Gong, Yue Qin, Xinhong Wang, Xiuling Zhi, Meng Lu, Sifeng Chen, Mingxia Gu, Jianyi Zhang, Jing-Dong J Han, Fei Lan, Dan Meng
Nucleic Acids Res. 2021 Feb 26; 49(4): 1972–1986. Published online 2021 Jan 27. doi: 10.1093/nar/gkab034
PMCID:
PMC7913776
AbstractArticlePDF–7.5M
13.
Chronic intermittent hypoxia promoted lung cancer stem cell-like properties via enhancing Bach1 expression
Shengyu Hao, Xiaodan Zhu, Zilong Liu, Xiaodan Wu, Shanqun Li, Pan Jiang, Liyan Jiang
Respir Res. 2021; 22: 58. Published online 2021 Feb 17. doi: 10.1186/s12931-021-01655-6
PMCID:
PMC7890965
AbstractArticlePDF–4.6M
14.
Bach1‐mediated suppression of p53 is inhibited by p19ARF independently of MDM2
Hironari Nishizawa, Kazushige Ota, Yoshihiro Dohi, Tsuyoshi Ikura, Kazuhiko Igarashi
Cancer Sci. 2012 May; 103(5): 897–903. Published online 2012 Apr 11. doi: 10.1111/j.1349-7006.2012.02244.x
PMCID:
PMC7659397
AbstractArticlePDF–513K
15.
Dysregulation of hypoxia-inducible factor-1α (Hif1α) expression in the Hmox1-deficient placenta
Hui Zhao, Purnima Narasimhan, Flora Kalish, Ronald J. Wong, David K. Stevenson
Placenta. 2020 Sep 15; 99: 108–116. doi: 10.1016/j.placenta.2020.07.015
PMCID:
PMC7549641
AbstractArticle
16.
Bach1 promotes muscle regeneration through repressing Smad-mediated inhibition of myoblast differentiation
Katsushi Suzuki, Mitsuyo Matsumoto, Yasutake Katoh, Liang Liu, Kyoko Ochiai, Yuta Aizawa, Ryoichi Nagatomi, Hiroshi Okuno, Eiji Itoi, Kazuhiko Igarashi
PLoS One. 2020; 15(8): e0236781. Published online 2020 Aug 10. doi: 10.1371/journal.pone.0236781
PMCID:
PMC7416950
AbstractArticlePDF–6.9M
17.
Ferroptosis is controlled by the coordinated transcriptional regulation of glutathione and labile iron metabolism by the transcription factor BACH1
Hironari Nishizawa, Mitsuyo Matsumoto, Tomohiko Shindo, Daisuke Saigusa, Hiroki Kato, Katsushi Suzuki, Masaki Sato, Yusho Ishii, Hiroaki Shimokawa, Kazuhiko Igarashi
J Biol Chem. 2020 Jan 3; 295(1): 69–82. Published online 2019 Nov 18. doi: 10.1074/jbc.RA119.009548
PMCID:
PMC6952604
AbstractArticlePDF–2.5M
18.
Developmental conservation of microRNA gene localization at the nuclear periphery
Eralda Salataj, Chrysoula Stathopoulou, Róbert A. Hafþórsson, Christoforos Nikolaou, Charalampos G. Spilianakis
PLoS One. 2019; 14(11): e0223759. Published online 2019 Nov 4. doi: 10.1371/journal.pone.0223759
PMCID:
PMC6827902
AbstractArticlePDF–4.0M
19.
The BACH1-HMOX1 regulatory axis is indispensable for proper macrophage subtype specification and skeletal muscle regeneration
Andreas Patsalos, Petros Tzerpos, Laszlo Halasz, Gergely Nagy, Attila Pap, Nikolas Giannakis, Konstantina Lyroni, Vasiliki Koliaraki, Eva Pintye, Balazs Dezso, George Kollias, Charalampos G Spilianakis, Laszlo Nagy
J Immunol. Author manuscript; available in PMC 2020 Sep 15.
Published in final edited form as: J Immunol. 2019 Sep 15; 203(6): 1532–1547. Published online 2019 Aug 12. doi: 10.4049/jimmunol.1900553
PMCID:
PMC6736746
AbstractArticlePDF–2.2M
20.
Salvianolic acid B, an antioxidant derived from Salvia militarize, protects mice against γ-radiation-induced damage through Nrf2/Bach1
Ruifang Zhou, Haishan Long, Bei Zhang, Zhizhao Lao, Quanyu Zheng, Tiancheng Wang, Yongxin Zhang, Qingguang Wu, Xiaoping Lai, Geng Li, Lizhu Lin
Mol Med Rep. 2019 Feb; 19(2): 1309–1317. Published online 2018 Dec 3. doi: 10.3892/mmr.2018.9718
PMCID:
PMC6323199
AbstractArticlePDF–1.3M

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