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Items: 1 to 20 of 60

1.
Integrin alphavbeta6 mediates the potential for colon cancer cells to colonize in and metastasize to the liver
Guang‐Yun Yang, Ke‐Sen Xu, Zhong‐Qing Pan, Zhao‐Yang Zhang, Yue‐Tang Mi, Jin‐Shen Wang, Rong Chen, Jun Niu
Cancer Sci. 2008 May; 99(5): 879–887. Published online 2008 Feb 20. doi: 10.1111/j.1349-7006.2008.00762.x
PMCID:
PMC11158270
AbstractArticlePDF–2.0M
2.
Knockout of integrin αvβ6 protects against renal inflammation in chronic kidney disease by reduction of pro-inflammatory macrophages
Changjian Zhu, Ruilin Zheng, Xu Han, Ziwen Tang, Feng Li, Xinrong Hu, Ruoni Lin, Jiani Shen, Qiaoqiao Pei, Rong Wang, Guangyan Wei, Zhenwei Peng, Wei Chen, Zhou Liang, Yi Zhou
Cell Death Dis. 2024 Jun; 15(6): 397. Published online 2024 Jun 6. doi: 10.1038/s41419-024-06785-5
PMCID:
PMC11156928
AbstractArticlePDF–13M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
αVβ8 integrin targeting to prevent posterior capsular opacification
Mahbubul H. Shihan, Samuel G. Novo, Yan Wang, Dean Sheppard, Amha Atakilit, Thomas D. Arnold, Nicole M. Rossi, Adam P. Faranda, Melinda K. Duncan
JCI Insight. 2021 Nov 8; 6(21): e145715. Published online 2021 Nov 8. doi: 10.1172/jci.insight.145715
PMCID:
PMC8663568
AbstractArticlePDF–4.5M
5.
Epithelial-Macrophage Crosstalk Initiates Sterile Inflammation in Embryonic Skin
Oindrila Bhattacharjee, Uttkarsh Ayyangar, Ambika S. Kurbet, Vairavan Lakshmanan, Dasaradhi Palakodeti, Florent Ginhoux, Srikala Raghavan
Front Immunol. 2021; 12: 718005. Published online 2021 Oct 14. doi: 10.3389/fimmu.2021.718005
PMCID:
PMC8553113
AbstractArticlePDF–12M
6.
Nonpeptidergic neurons suppress mast cells via glutamate to maintain skin homeostasis
Shiqun Zhang, Tara N. Edwards, Virendra K. Chaudhri, Jianing Wu, Jonathan A. Cohen, Toshiro Hirai, Natalie Rittenhouse, Elizabeth G. Schmitz, Paul Yifan Zhou, Benjamin D. McNeil, Yi Yang, H. Richard Koerber, Tina L. Sumpter, Amanda C. Poholek, Brian M. Davis, Kathryn M. Albers, Harinder Singh, Daniel H. Kaplan
Cell. Author manuscript; available in PMC 2022 Apr 15.
Published in final edited form as: Cell. 2021 Mar 18 : S0092-8674(21)00287-7. Published online 2021 Mar 18. doi: 10.1016/j.cell.2021.03.002
PMCID:
PMC8052305
AbstractArticlePDF–1.2M
7.
Transgenic overexpression of ITGB6 in intestinal epithelial cells exacerbates dextran sulfate sodium‐induced colitis in mice
Haiyan Chen, Liubo Chen, Xin Wang, Xiaoxu Ge, Lifeng Sun, Zhanhuai Wang, Xiaoming Xu, Yongmao Song, Jing Chen, Qun Deng, Haiting Xie, Ting Chen, Yan Chen, Kefeng Ding, Jingjing Wu, Jian Wang
J Cell Mol Med. 2021 Mar; 25(5): 2679–2690. Published online 2021 Jan 24. doi: 10.1111/jcmm.16297
PMCID:
PMC7933932
AbstractArticlePDF–2.1M
8.
Competition for active TGFβ cytokine allows for selective retention of antigen-specific tissue resident memory T cells in the epidermal niche
Toshiro Hirai, Yi Yang, Yukari Zenke, Haiyue Li, Virendra K. Chaudhri, Jacinto S. De La Cruz Diaz, Paul Yifan Zhou, Breanna Anh-Thu Nguyen, Laurent Bartholin, Creg J. Workman, David W. Griggs, Dario A. A. Vignali, Harinder Singh, David Masopust, Daniel H. Kaplan
Immunity. Author manuscript; available in PMC 2022 Jan 12.
Published in final edited form as: Immunity. 2021 Jan 12; 54(1): 84–98.e5. Published online 2020 Nov 18. doi: 10.1016/j.immuni.2020.10.022
PMCID:
PMC7856016
AbstractArticlePDF–2.6M
9.
Integrin Requirement for Hippocampal Synaptic Plasticity and Spatial Memory
Chi-Shing Chan, Edwin J. Weeber, Sindhu Kurup, J. David Sweatt, Ronald L. Davis
J Neurosci. 2003 Aug 6; 23(18): 7107–7116. doi: 10.1523/JNEUROSCI.23-18-07107.2003
PMCID:
PMC6740650
AbstractArticlePDF–858K
10.
Characterization of integrin β6 and thrombospondin‐1 double‐null mice
Anna Ludlow, Karen O. Yee, Ruth Lipman, R. Bronson, P. Weinreb, Xiaozhu Huang, D. Sheppard, J. Lawler
J Cell Mol Med. 2005 Apr; 9(2): 421–437. Published online 2007 May 1. doi: 10.1111/j.1582-4934.2005.tb00367.x
PMCID:
PMC6740207
AbstractArticlePDF–3.3M
11.
Keratinocyte-derived TGFβ is not required to maintain skin immune homeostasis
Yi Yang, Yukari Zenke, Toshiro Hirai, Daniel H. Kaplan
J Dermatol Sci. Author manuscript; available in PMC 2020 May 7.
Published in final edited form as: J Dermatol Sci. 2019 May; 94(2): 290–297. Published online 2019 May 7. doi: 10.1016/j.jdermsci.2019.04.008
Correction in:
J Dermatol Sci. 2019 Sep; 95(3): 134.
PMCID:
PMC6602918
AbstractArticlePDF–1.2M
12.
INITIATION OF FIBROSIS IN THE INTEGRIN αVβ6 KNOCKOUT MICE
Wenjing Wu, Audrey E.K. Hutcheon, Sriniwas Sriram, Jennifer A. Tran, James D. Zieske
Exp Eye Res. Author manuscript; available in PMC 2020 Mar 1.
Published in final edited form as: Exp Eye Res. 2019 Mar; 180: 23–28. Published online 2018 Nov 28. doi: 10.1016/j.exer.2018.11.027
PMCID:
PMC6540115
AbstractArticlePDF–1.5M
13.
Keratinocyte-mediated activation of the cytokine TGFβ maintains skin-recirculating memory CD8+ T cells
Toshiro Hirai, Yukari Zenke, Yi Yang, Laurent Bartholin, Lalit K. Beura, David Masopust, Daniel H. Kaplan
Immunity. Author manuscript; available in PMC 2020 May 21.
Published in final edited form as: Immunity. 2019 May 21; 50(5): 1249–1261.e5. Published online 2019 Apr 2. doi: 10.1016/j.immuni.2019.03.002
PMCID:
PMC6531326
AbstractArticlePDF–1.8M
14.
Transcriptome Analysis of Cardiac Hypertrophic Growth in MYBPC3-Null Mice Suggests Early Responders in Hypertrophic Remodeling
Emily Farrell, Annie E. Armstrong, Adrian C. Grimes, Francisco J. Naya, Willem J. de Lange, J. Carter Ralphe
Front Physiol. 2018; 9: 1442. Published online 2018 Oct 25. doi: 10.3389/fphys.2018.01442
PMCID:
PMC6210548
AbstractArticlePDF–3.8M
15.
Exosomal αvβ6 Integrin Is Required for Monocyte M2 Polarization In Prostate Cancer
Huimin Lu, Nicholas Bowler, Larry A. Harshyne, D. Craig Hooper, Shiv Ram Krishn, Senem Kurtoglu, Carmine Fedele, Qin Liu, Hsin-Yao Tang, Andrew V. Kossenkov, William K. Kelly, Kerith Wang, Rhonda B. Kean, Paul H. Weinreb, Lei Yu, Anindita Dutta, Paolo Fortina, Adam Ertel, Maria Stanczak, Flemming Forsberg, Dmitry I. Gabrilovich, David W. Speicher, Dario C. Altieri, Lucia R. Languino
Matrix Biol. Author manuscript; available in PMC 2019 Sep 1.
Published in final edited form as: Matrix Biol. 2018 Sep; 70: 20–35. Published online 2018 Mar 9. doi: 10.1016/j.matbio.2018.03.009
PMCID:
PMC6081240
AbstractArticlePDF–1.1M
16.
YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis
Chuwen Lin, Erica Yao, Kuan Zhang, Xuan Jiang, Stacey Croll, Katherine Thompson-Peer, Pao-Tien Chuang
eLife. 2017; 6: e21130. Published online 2017 Mar 21. doi: 10.7554/eLife.21130
PMCID:
PMC5360446
AbstractArticlePDF–11M
17.
Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-ß
Javed Mohammed, Lalit K Beura, Aleh Bobr, Brian Astry, Brian Chicoine, Sakeen W Kashem, Nathan E Welty, Botond Z Igyártó, Sathi Wijeyesinghe, Emily A Thompson, Catherine Matte, Laurent Bartholin, Alesia Kaplan, Dean Sheppard, Alina G Bridges, Warren D Shlomchik, David Masopust, Daniel H Kaplan
Nat Immunol. Author manuscript; available in PMC 2017 Apr 1.
Published in final edited form as: Nat Immunol. 2016 Apr; 17(4): 414–421. Published online 2016 Feb 22. doi: 10.1038/ni.3396
PMCID:
PMC5135085
AbstractArticlePDF–1.5M
18.
Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6 Expression
Amanda L. Tatler, Anthony Habgood, Joanne Porte, Alison E. John, Anastasios Stavrou, Emily Hodge, Cheryl Kerama-Likoko, Shelia M. Violette, Paul H. Weinreb, Alan J. Knox, Geoffrey Laurent, Helen Parfrey, Paul John Wolters, William Wallace, Siegfried Alberti, Alfred Nordheim, Gisli Jenkins
J Biol Chem. 2016 Apr 29; 291(18): 9540–9553. Published online 2016 Feb 9. doi: 10.1074/jbc.M115.692368
PMCID:
PMC4850293
AbstractArticlePDF–2.7M
19.
Periodontal Pathogens Invade Gingiva and Aortic Adventitia and Elicit Inflammasome Activation in αvβ6 Integrin-Deficient Mice
Irina M. Velsko, Sasanka S. Chukkapalli, Mercedes F. Rivera-Kweh, Donghang Zheng, Ikramuddin Aukhil, Alexandra R. Lucas, Hannu Larjava, Lakshmyya Kesavalu
Infect Immun. 2015 Dec; 83(12): 4582–4593. Prepublished online 2015 Sep 14. Published online 2015 Nov 10. doi: 10.1128/IAI.01077-15
PMCID:
PMC4645375
AbstractArticlePDF–1.8M
20.
Influenza Promotes Collagen Deposition via αvβ6 Integrin-mediated Transforming Growth Factor β Activation
Lisa Jolly, Anastasios Stavrou, Gilles Vanderstoken, Victoria A. Meliopoulos, Anthony Habgood, Amanda L. Tatler, Joanne Porte, Alan Knox, Paul Weinreb, Shelia Violette, Tracy Hussell, Martin Kolb, Martin R. Stampfli, Stacey Schultz-Cherry, Gisli Jenkins
J Biol Chem. 2014 Dec 19; 289(51): 35246–35263. Published online 2014 Oct 22. doi: 10.1074/jbc.M114.582262
PMCID:
PMC4271213
AbstractArticlePDF–4.3M

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