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Select item 108446391.

NDUFS7 variant in dogs with Leigh syndrome and its functional validation in a Drosophila melanogaster model

Matthias Christen, Anne Gregor, Rodrigo Gutierrez-Quintana, Jos Bongers, Angie Rupp, Jacques Penderis, G. Diane Shelton, Vidhya Jagannathan, Christiane Zweier, Tosso Leeb

Sci Rep. 2024; 14: 2975. Published online 2024 Feb 5. doi: 10.1038/s41598-024-53314-7

PMCID:: PMC10844639

Abstract Article PDF–2.3M

Select item 107182852.

Phospholipids can regulate complex I assembly independent of their role in maintaining mitochondrial membrane integrity

Anjaneyulu Murari, Shauna-Kay Rhooms, Divya Vimal, Kaniz Fatima Binte Hossain, Sanjay Saini, Maximino Villanueva, Michael Schlame, Edward Owusu-Ansah

Cell Rep. Author manuscript; available in PMC 2023 Dec 13.

Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112846. Published online 2023 Jul 29. doi: 10.1016/j.celrep.2023.112846

PMCID:: PMC10718285

Abstract Article PDF–2.8M

Select item 106228403.

Cardiolipin prolongs the lifetimes of respiratory proteins in Drosophila flight muscle

Mindong Ren, Yang Xu, Colin K.L. Phoon, Hediye Erdjument-Bromage, Thomas A. Neubert, Michael Schlame

J Biol Chem. 2023 Oct; 299(10): 105241. Published online 2023 Sep 9. doi: 10.1016/j.jbc.2023.105241

PMCID:: PMC10622840

Abstract Article PDF–1.2M

Select item 102706254.

RNAi of Complex I and V of the electron transport chain in glutamate neurons extends life span, increases sleep, and decreases locomotor activity in Drosophila melanogaster

Jessie E. Landis, Kevin Sungu, Hannah Sipe, Jeffrey M. Copeland

PLoS One. 2023; 18(6): e0286828. Published online 2023 Jun 15. doi: 10.1371/journal.pone.0286828

PMCID:: PMC10270625

Abstract Article PDF–1.2M

Select item 100361225.

Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state

Abhilash Padavannil, Anjaneyulu Murari, Shauna-Kay Rhooms, Edward Owusu-Ansah, James A Letts

eLife. 2023; 12: e84415. Published online 2023 Mar 23. doi: 10.7554/eLife.84415

PMCID:: PMC10036122

Abstract Article PDF–12M

Select item 99772796.

Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster

Ahmed-Noor A Agip, Injae Chung, Alvaro Sanchez-Martinez, Alexander J Whitworth, Judy Hirst

eLife. 2023; 12: e84424. Published online 2023 Jan 9. doi: 10.7554/eLife.84424

PMCID:: PMC9977279

Abstract Article PDF–6.3M

Select item 99534517.

Mitochondrial Neurodegeneration: Lessons from Drosophila melanogaster Models

Michele Brischigliaro, Erika Fernandez-Vizarra, Carlo Viscomi

Biomolecules. 2023 Feb; 13(2): 378. Published online 2023 Feb 16. doi: 10.3390/biom13020378

PMCID:: PMC9953451

Abstract Article PDF–1.6M

Select item 97947288.

The membrane domain of respiratory complex I accumulates during muscle aging in Drosophila melanogaster

Kaniz Fatima Binte Hossain, Anjaneyulu Murari, Bibhuti Mishra, Edward Owusu-Ansah

Sci Rep. 2022; 12: 22433. Published online 2022 Dec 27. doi: 10.1038/s41598-022-26414-5

PMCID:: PMC9794728

Abstract Article PDF–3.7M

Select item 97134319.

Transcriptome analysis of FOXO-dependent hypoxia gene expression identifies Hipk as a regulator of low oxygen tolerance in Drosophila

Kate Ding, Elizabeth C Barretto, Michael Johnston, Byoungchun Lee, Marco Gallo, Savraj S Grewal

G3 (Bethesda) 2022 Dec; 12(12): jkac263. Published online 2022 Oct 6. doi: 10.1093/g3journal/jkac263

PMCID:: PMC9713431

Abstract Article PDF–1.0M

Select item 964406410.

Loss of Drosophila Clueless differentially affects the mitochondrial proteome compared to loss of Sod2 and Pink1

Aditya Sen, Rachel T. Cox

Front Physiol. 2022; 13: 1004099. Published online 2022 Oct 26. doi: 10.3389/fphys.2022.1004099

PMCID:: PMC9644064

Abstract Article PDF–4.2M

Select item 909466711.

IDH2-mediated regulation of the biogenesis of the oxidative phosphorylation system

Anjaneyulu Murari, Naga S. V. Goparaju, Shauna-Kay Rhooms, Kaniz F. B. Hossain, Felix G. Liang, Christian J. Garcia, Cindy Osei, Tong Liu, Hong Li, Richard N. Kitsis, Rajesh Patel, Edward Owusu-Ansah

Sci Adv. 2022 May; 8(19): eabl8716. Published online 2022 May 11. doi: 10.1126/sciadv.abl8716

PMCID:: PMC9094667

Abstract Article PDF–21M

Select item 903811912.

Targeting metabolic pathways for extension of lifespan and healthspan across multiple species

Andrey A. Parkhitko, Elizabeth Filine, Stephanie E. Mohr, Alexey Moskalev, Norbert Perrimon

Ageing Res Rev. Author manuscript; available in PMC 2022 Apr 25.

Published in final edited form as: Ageing Res Rev. 2020 Dec; 64: 101188. Published online 2020 Oct 5. doi: 10.1016/j.arr.2020.101188

PMCID:: PMC9038119

Abstract Article PDF–2.0M

Select item 866448613.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 864520714.

In vivo proximity biotin ligation identifies the interactome of Egalitarian, a Dynein cargo adaptor

Frederick C. Baker, Hannah Neiswender, Rajalakshmi Veeranan-Karmegam, Graydon B. Gonsalvez

Development. 2021 Nov 15; 148(22): dev199935. Published online 2021 Nov 18. doi: 10.1242/dev.199935

PMCID:: PMC8645207

Abstract Article

Select item 846882715.

Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders

Stefano Sechi, Angela Karimpour-Ghahnavieh, Anna Frappaolo, Laura Di Francesco, Roberto Piergentili, Eugenia Schininà, Pier Paolo D’Avino, Maria Grazia Giansanti

Cells. 2021 Sep; 10(9): 2336. Published online 2021 Sep 6. doi: 10.3390/cells10092336

PMCID:: PMC8468827

Abstract Article PDF–4.1M

Select item 834666616.

Dissecting the concordant and disparate roles of NDUFAF3 and NDUFAF4 in mitochondrial complex I biogenesis

Anjaneyulu Murari, Shauna-Kay Rhooms, Christian Garcia, Tong Liu, Hong Li, Bibhuti Mishra, Cassie Deshong, Edward Owusu-Ansah

iScience. 2021 Aug 20; 24(8): 102869. Published online 2021 Jul 16. doi: 10.1016/j.isci.2021.102869

PMCID:: PMC8346666

Abstract Article PDF–6.1M

Select item 765970917.

An antibody toolbox to track complex I assembly defines AIF’s mitochondrial function

Anjaneyulu Murari, Shauna-Kay Rhooms, Naga Sri Goparaju, Maximino Villanueva, Edward Owusu-Ansah

J Cell Biol. 2020 Oct 5; 219(10): e202001071. Published online 2020 Sep 16. doi: 10.1083/jcb.202001071

PMCID:: PMC7659709

Abstract Article PDF–7.1M

Select item 728907718.

Insights from Drosophila on mitochondrial complex I

Shauna-Kay Rhooms, Anjaneyulu Murari, Naga Sri Vidya Goparaju, Maximino Vilanueva, Edward Owusu-Ansah

Cell Mol Life Sci. 2020 Feb; 77(4): 607–618. Published online 2019 Sep 4. doi: 10.1007/s00018-019-03293-0

PMCID:: PMC7289077

Abstract Article PDF–881K

Select item 696157819.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 692398820.

Drosophila Prominin-like, a homolog of CD133, interacts with ND20 to maintain mitochondrial function

Xuexiang Wang, Huimei Zheng, Zexiao Jia, Zhaoying Lei, Mengyao Li, Qianqian Zhuang, Hui Zhou, Yue Qiu, Yong Fu, Xiaohang Yang, Yongmei Xi, Qingfeng Yan

Cell Biosci. 2019; 9: 101. Published online 2019 Dec 19. doi: 10.1186/s13578-019-0365-0