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Select item 103916751.

The tardigrade Dsup protein enhances radioresistance in Drosophila melanogaster and acts as an unspecific repressor of transcription

Mikhail Zarubin, Talyana Azorskaya, Olga Kuldoshina, Sergey Alekseev, Semen Mitrofanov, Elena Kravchenko

iScience. 2023 Jul 21; 26(7): 106998. Published online 2023 May 29. doi: 10.1016/j.isci.2023.106998

PMCID:: PMC10391675

Abstract Article PDF–3.0M

Select item 101927202.

HR repair pathway plays a crucial role in maintaining neural stem cell fate under irradiation stress

Xiao Xu, Huanping An, Cheng Wu, Rong Sang, Litao Wu, Yuhan Lou, Xiaohang Yang, Yongmei Xi

Life Sci Alliance. 2023 Aug; 6(8): e202201802. Published online 2023 May 17. doi: 10.26508/lsa.202201802

PMCID:: PMC10192720

Abstract Article PDF–2.9M

Select item 82827493.

Polyploid mitosis and depolyploidization promote chromosomal instability and tumor progression in a Notch-induced tumor model

Xian-Feng Wang, Sheng-An Yang, Shangyu Gong, Chih-Hsuan Chang, Juan Martin Portilla, Deeptiman Chatterjee, Jerome Irianto, Hongcun Bao, Yi-Chun Huang, Wu-Min Deng

Dev Cell. Author manuscript; available in PMC 2022 Jul 12.

Published in final edited form as: Dev Cell. 2021 Jul 12; 56(13): 1976–1988.e4. Published online 2021 Jun 18. doi: 10.1016/j.devcel.2021.05.017

PMCID:: PMC8282749

Abstract Article PDF–3.2M

Select item 82758074.

VCP maintains nuclear size by regulating the DNA damage-associated MDC1–p53–autophagy axis in Drosophila

Ya-Chu Chang, Yu-Xiang Peng, Bo-Hua Yu, Henry C. Chang, Pei-Shin Liang, Ting-Yi Huang, Chao-Jie Shih, Li-An Chu, Tzu-Kang Sang

Nat Commun. 2021; 12: 4258. Published online 2021 Jul 12. doi: 10.1038/s41467-021-24556-0

PMCID:: PMC8275807

Abstract Article PDF–5.6M

Select item 81072845.

ERR and dPECR Suggest a Link Between Neuroprotection and the Regulation of Ethanol Consumption Preference

Laura Velo Escarcena, Margarita Neufeld, Marcella Rietschel, Rainer Spanagel, Henrike Scholz

Front Psychiatry. 2021; 12: 655816. Published online 2021 Apr 26. doi: 10.3389/fpsyt.2021.655816

PMCID:: PMC8107284

Abstract Article PDF–1.7M

Select item 78861936.

Kinetochore-independent mechanisms of sister chromosome separation

Hannah Vicars, Travis Karg, Brandt Warecki, Ian Bast, William Sullivan

PLoS Genet. 2021 Jan; 17(1): e1009304. Published online 2021 Jan 29. doi: 10.1371/journal.pgen.1009304

PMCID:: PMC7886193

Abstract Article PDF–2.8M

Select item 78803787.

Evaluation of the geroprotective effects of withaferin A in Drosophila melanogaster

Liubov Koval, Nadezhda Zemskaya, Alexander Aliper, Alex Zhavoronkov, Alexey Moskalev

Aging (Albany NY) 2021 Jan 31; 13(2): 1817–1841. Published online 2021 Jan 26. doi: 10.18632/aging.202572

PMCID:: PMC7880378

Abstract Article PDF–2.0M

Select item 69328908.

Identification of novel genes associated with longevity in Drosophila melanogaster - a computational approach

Bethany S. Hall, Yvonne A. Barnett, Jonathan J. Crofts, Nadia Chuzhanova

Aging (Albany NY) 2019 Dec 15; 11(23): 11244–11267. Published online 2019 Dec 3. doi: 10.18632/aging.102527

PMCID:: PMC6932890

Abstract Article PDF–1.2M

Select item 68845799.

Transcription elongation factor AFF2/FMR2 regulates expression of expanded GGGGCC repeat-containing C9ORF72 allele in ALS/FTD

Yeliz Yuva-Aydemir, Sandra Almeida, Gopinath Krishnan, Tania F. Gendron, Fen-Biao Gao

Nat Commun. 2019; 10: 5466. Published online 2019 Nov 29. doi: 10.1038/s41467-019-13477-8

PMCID:: PMC6884579

Abstract Article PDF–2.5M

Select item 672460410.

Drosophila p53 directs nonapoptotic programs in postmitotic tissue

Paula Kurtz, Amanda E. Jones, Bhavana Tiwari, Nichole Link, Annika Wylie, Charles Tracy, Helmut Krämer, John M. Abrams

Mol Biol Cell. 2019 May 15; 30(11): 1339–1351. doi: 10.1091/mbc.E18-12-0791

PMCID:: PMC6724604

Abstract Article PDF–1.2M

Select item 669866111.

A Drosophila cell-free system that senses DNA breaks and triggers phosphorylation signalling

Lisa Harpprecht, Sandro Baldi, Tamas Schauer, Andreas Schmidt, Tanja Bange, Maria S Robles, Elisabeth Kremmer, Axel Imhof, Peter B Becker

Nucleic Acids Res. 2019 Aug 22; 47(14): 7444–7459. Published online 2019 May 31. doi: 10.1093/nar/gkz473

PMCID:: PMC6698661

Abstract Article PDF–4.3M

Select item 651102112.

Partial inhibition of the overactivated Ku80-dependent DNA repair pathway rescues neurodegeneration in C9ORF72-ALS/FTD

Rodrigo Lopez-Gonzalez, Dejun Yang, Mochtar Pribadi, Tanya S. Kim, Gopinath Krishnan, So Yoen Choi, Soojin Lee, Giovanni Coppola, Fen-Biao Gao

Proc Natl Acad Sci U S A. 2019 May 7; 116(19): 9628–9633. Published online 2019 Apr 24. doi: 10.1073/pnas.1901313116

PMCID:: PMC6511021

Abstract Article PDF–1.3M

Select item 631732013.

Timely double-strand break repair and pathway choice in pericentromeric heterochromatin depend on the histone demethylase dKDM4A

Aniek Janssen, Serafin U. Colmenares, Timothy Lee, Gary H. Karpen

Genes Dev. 2019 Jan 1; 33(1-2): 103–115. doi: 10.1101/gad.317537.118

PMCID:: PMC6317320

Abstract Article PDF–2.1M

Select item 602824914.

The Histone Demethylase KDM5 Is Essential for Larval Growth in Drosophila

Coralie Drelon, Helen M. Belalcazar, Julie Secombe

Genetics. 2018 Jul; 209(3): 773–787. Published online 2018 May 15. doi: 10.1534/genetics.118.301004

PMCID:: PMC6028249

Abstract Article PDF–2.0M

Select item 570780515.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900216.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 528983017.

DNA Repair in Drosophila: Mutagens, Models, and Missing Genes

Jeff Sekelsky

Genetics. 2017 Feb; 205(2): 471–490. Published online 2017 Jan 31. doi: 10.1534/genetics.116.186759

PMCID:: PMC5289830

Abstract Article PDF–891K

Select item 507911118.

C9orf72 dipeptide repeats impair the assembly, dynamics and function of membrane-less organelles

Kyung-Ha Lee, Peipei Zhang, Hong Joo Kim, Diana Mitrea, Mohona Sarkar, Brian Freibaum, Jaclyn Cika, Maura Coughlin, James Messing, Amandine Molliex, Brian Maxwell, Nam Chul Kim, Jamshid Temirov, Jennifer Moore, Regina-Maria Kolaitis, Timothy Shaw, Bing Bai, Junmin Peng, Richard Kriwacki, J. Paul Taylor

Cell. Author manuscript; available in PMC 2017 Oct 20.

Published in final edited form as: Cell. 2016 Oct 20; 167(3): 774–788.e17. doi: 10.1016/j.cell.2016.10.002

PMCID:: PMC5079111

Abstract Article PDF–2.3M

Select item 488965819.

mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster

Gildas Lepennetier, Francesco Catania

G3 (Bethesda) 2016 Jun; 6(6): 1617–1626. Published online 2016 Mar 28. doi: 10.1534/g3.116.029231

PMCID:: PMC4889658

Abstract Article PDF–1.5M

Select item 473800520.

Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes

Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Bezginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, W. Brent Derry, Elisabeth R. Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Data Brief. 2016 Mar; 6: 715–721. Published online 2015 Dec 12. doi: 10.1016/j.dib.2015.11.062

PMCID:: PMC4738005

Abstract Article PDF–205K

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