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Select item 94034401.

Targeting peptidyl-prolyl isomerase 1 in experimental pulmonary arterial hypertension

Nabham Rai, Akylbek Sydykov, Baktybek Kojonazarov, Jochen Wilhelm, Grégoire Manaud, Swathi Veeroju, Clemens Ruppert, Frédéric Perros, Hossein Ardeschir Ghofrani, Norbert Weissmann, Werner Seeger, Ralph T. Schermuly, Tatyana Novoyatleva

Eur Respir J. 2022 Aug; 60(2): 2101698. Published online 2022 Aug 25. doi: 10.1183/13993003.01698-2021

PMCID:: PMC9403440

Abstract Article PDF–1.1M

Select item 90009792.

Pin1 aggravates renal injury induced by ischemia and reperfusion in rats via Nrf2/HO-1 mediated endoplasmic reticulum stress

Honglin Yu, Guanjun Jiang, Wei Hu, Changgeng Xu

Acta Cir Bras. 2022; 37(1): e370101. Published online 2022 Apr 8. doi: 10.1590/acb370101

PMCID:: PMC9000979

Abstract Article PDF–2.5M

Select item 83492973.

The Suppression of Pin1-Alleviated Oxidative Stress through the p38 MAPK Pathway in Ischemia- and Reperfusion-Induced Acute Kidney Injury

Xiaojie Zhao, Dan Wang, Shanshan Wan, Xiuheng Liu, Wei Wang, Lei Wang

Oxid Med Cell Longev. 2021; 2021: 1313847. Published online 2021 Jul 30. doi: 10.1155/2021/1313847

PMCID:: PMC8349297

Abstract Article PDF–2.8M

Select item 58199294.

Pin1 facilitates isoproterenol-induced cardiac fibrosis and collagen deposition by promoting oxidative stress and activating the MEK1/2-ERK1/2 signal transduction pathway in rats

Xian Wu, Mingjiang Li, Su-Qin Chen, Sha Li, Furong Guo

Int J Mol Med. 2018 Mar; 41(3): 1573–1583. Published online 2017 Dec 29. doi: 10.3892/ijmm.2017.3354

PMCID:: PMC5819929

Abstract Article PDF–1.0M

Select item 53852205.

Pathological Role of Peptidyl-Prolyl Isomerase Pin1 in the Disruption of Synaptic Plasticity in Alzheimer's Disease

Lingyan Xu, Zhiyun Ren, Frances E. Chow, Richard Tsai, Tongzheng Liu, Flavio Rizzolio, Silvia Boffo, Yungen Xu, Shaohui Huang, Carol F. Lippa, Yuesong Gong

Neural Plast. 2017; 2017: 3270725. Published online 2017 Mar 26. doi: 10.1155/2017/3270725

PMCID:: PMC5385220

Abstract Article PDF–3.5M

Select item 44236216.

Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer’s disease

Chun-Hau Chen, Wenzong Li, Rukhsana Sultana, Mi-Hyeon You, Asami Kondo, Kooroch Shahpasand, Byeong Mo Kim, ManLi Luo, Morris Nechama, Yu-Min Lin, Yandan Yao, Tae Ho Lee, Xiao Zhen Zhou, Aaron M. Swomley, D. Allan Butterfield, Yan Zhang, Kun Ping Lu

Neurobiol Dis. Author manuscript; available in PMC 2016 Apr 1.

Published in final edited form as: Neurobiol Dis. 2015 Apr; 76: 13–23. Published online 2015 Jan 6. doi: 10.1016/j.nbd.2014.12.027

PMCID:: PMC4423621

Abstract Article PDF–1.8M

Select item 40967677.

Pin1 Deficiency Causes Endothelial Dysfunction and Hypertension

Valorie L. Chiasson, Nidhi Munshi, Piyali Chatterjee, Kristina J. Young, Brett M. Mitchell

Hypertension. Author manuscript; available in PMC 2014 Jul 15.

Published in final edited form as: Hypertension. 2011 Sep; 58(3): 431–438. Published online 2011 Aug 1. doi: 10.1161/HYPERTENSIONAHA.111.172338

PMCID:: PMC4096767

Abstract Article PDF–621K

Select item 38944578.

Pin1, a new player in the fate of HIF-1α degradation: an hypothetical mechanism inside vascular damage as Alzheimer’s disease risk factor

Elena Lonati, Anna Brambilla, Chiara Milani, Massimo Masserini, Paola Palestini, Alessandra Bulbarelli

Front Cell Neurosci. 2014; 8: 001. Published online 2014 Jan 17. doi: 10.3389/fncel.2014.00001

PMCID:: PMC3894457

Abstract Article PDF–1.2M

Select item 38497969.

Peptidyl-Prolyl Isomerase 1 Regulates Protein Phosphatase 2A-Mediated Topographic Phosphorylation of Neurofilament Proteins

Parvathi Rudrabhatla, Wayne Albers, Harish C. Pant

J Neurosci. 2009 Nov 25; 29(47): 14869–14880. doi: 10.1523/JNEUROSCI.4469-09.2009

PMCID:: PMC3849796

Abstract Article PDF–2.9M

Select item 374210910.

Regulation of Cardiac Hypertrophic Signaling by Prolyl Isomerase Pin1

Haruhiro Toko, Mathias H. Konstandin, Shirin Doroudgar, Lucia Ormachea, Eri Joyo, Anya Y. Joyo, Shabana Din, Natalie A. Gude, Brett Collins, Mirko Völkers, Donna J. Thuerauf, Christopher C. Glembotski, Chun-Hau Chen, Kun Ping Lu, Oliver J. Müller, Takafumi Uchida, Mark A. Sussman

Circ Res. Author manuscript; available in PMC 2014 Apr 26.

Published in final edited form as: Circ Res. 2013 Apr 26; 112(9): 1244–1252. Published online 2013 Mar 13. doi: 10.1161/CIRCRESAHA.113.301084

PMCID:: PMC3742109

Abstract Article PDF–3.2M

Select item 359783311.

Isomerase Pin1 Stimulates Dephosphorylation of Tau Protein at Cyclin-dependent Kinase (Cdk5)-dependent Alzheimer Phosphorylation Sites

Taeko Kimura, Koji Tsutsumi, Masato Taoka, Taro Saito, Masami Masuda-Suzukake, Koichi Ishiguro, Florian Plattner, Takafumi Uchida, Toshiaki Isobe, Masato Hasegawa, Shin-ichi Hisanaga

J Biol Chem. 2013 Mar 15; 288(11): 7968–7977. Published online 2013 Jan 28. doi: 10.1074/jbc.M112.433326

PMCID:: PMC3597833

Abstract Article PDF–2.1M

Select item 343451912.

Prolyl Isomerase Pin1 Regulates Neuronal Differentiation via β-Catenin

Kazuhiro Nakamura, Isao Kosugi, Daniel Y. Lee, Angela Hafner, David A. Sinclair, Akihide Ryo, Kun Ping Lu

Mol Cell Biol. 2012 Aug; 32(15): 2966–2978. doi: 10.1128/MCB.05688-11

PMCID:: PMC3434519

Abstract Article PDF–3.1M

Select item 338765513.

Mutant p53: one name, many proteins

William A. Freed-Pastor, Carol Prives

Genes Dev. 2012 Jun 15; 26(12): 1268–1286. doi: 10.1101/gad.190678.112

PMCID:: PMC3387655

Abstract Article PDF–412K

Select item 325576914.

Regulation of Estrogen Receptor α N-Terminus Conformation and Function by Peptidyl Prolyl Isomerase Pin1

Prashant Rajbhandari, Greg Finn, Natalia M. Solodin, Kiran K. Singarapu, Sarata C. Sahu, John L. Markley, Kelley J. Kadunc, Stephanie J. Ellison-Zelski, Anastasia Kariagina, Sandra Z. Haslam, Kun Ping Lu, Elaine T. Alarid

Mol Cell Biol. 2012 Jan; 32(2): 445–457. doi: 10.1128/MCB.06073-11

PMCID:: PMC3255769

Abstract Article PDF–1.6M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 303137716.

The prolyl isomerase Pin1 acts as a novel molecular switch for TNF-α–induced priming of the NADPH oxidase in human neutrophils

Tarek Boussetta, Marie-Anne Gougerot-Pocidalo, Gilles Hayem, Silvia Ciappelloni, Houssam Raad, Riad Arabi Derkawi, Odile Bournier, Yolande Kroviarski, Xiao Zhen Zhou, James S. Malter, Ping K. Lu, Aghleb Bartegi, Pham My-Chan Dang, Jamel El-Benna

Blood. 2010 Dec 23; 116(26): 5795–5802. Prepublished online 2010 Oct 18. doi: 10.1182/blood-2010-03-273094