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Items: 1 to 20 of 58

1.
Expression of integrin β-7 is epigenetically enhanced in multiple myeloma subgroups with high-risk cytogenetics
Samrat Roy Choudhury, Stephanie D. Byrum, Duah Alkam, Cody Ashby, Fenghuang Zhan, Alan J. Tackett, Frits Van Rhee
Clin Epigenetics. 2023; 15: 18. Published online 2023 Feb 4. doi: 10.1186/s13148-023-01433-9
PMCID:
PMC9898982
AbstractArticlePDF–4.8M
2.
Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors
Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen
Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638
PMCID:
PMC9106303
AbstractArticlePDF–918K
3.
Integrated analysis reveals the participation of IL4I1, ITGB7, and FUT7 in reshaping the TNBC immune microenvironment by targeting glycolysis
Tao Xu, Jiahao Liu, Yu Xia, Zhi Wang, Xingrui Li, Qinglei Gao
Ann Med. 2021; 53(1): 916–928. Published online 2021 Jun 16. doi: 10.1080/07853890.2021.1937694
PMCID:
PMC8604452
AbstractArticlePDF–3.6M
4.
Binding of HIV-1 virions to α4β7 expressing cells and impact of antagonizing α4β7 on HIV-1 infection of primary CD4+ T cells
Chang Li, Wei Jin, Tao Du, Biao Wu, Yalan Liu, Robin J. Shattock, Qinxue Hu
Virol Sin. 2014 Dec; 29(6): 381–392. Published online 2014 Dec 10. doi: 10.1007/s12250-014-3525-8
Correction in:
Virol Sin. 2015 Apr; 30(2): 162.
PMCID:
PMC8206286
AbstractArticlePDF–2.4M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
The V2 loop of HIV gp120 delivers costimulatory signals to CD4+ T cells through Integrin α4β7 and promotes cellular activation and infection
Livia R. Goes, Alia Sajani, Aida Sivro, Ronke Olowojesiku, Jocelyn C. Ray, Ian Perrone, Jason Yolitz, Alexandre Girard, Louise Leyre, Constantinos Kurt Wibmer, Lynn Morris, Giacomo Gorini, Genoveffa Franchini, Rosemarie D. Mason, Mario Roederer, Saurabh Mehandru, Marcelo A. Soares, Claudia Cicala, Anthony S. Fauci, James Arthos
Proc Natl Acad Sci U S A. 2020 Dec 22; 117(51): 32566–32573. Published online 2020 Dec 7. doi: 10.1073/pnas.2011501117
PMCID:
PMC7768698
AbstractArticlePDF–822K
7.
The association of α4β7 expression with HIV acquisition and disease progression in people who inject drugs and men who have sex with men: Case control studies
Alyssa R. Martin, Eshan U. Patel, Charles Kirby, Jacquie Astemborski, Gregory D. Kirk, Shruti H. Mehta, Kyle Marshall, Holly Janes, Ashley Clayton, Lawrence Corey, Scott M. Hammer, Magdalena E. Sobieszczyk, James Arthos, Claudia Cicala, Andrew D. Redd, Thomas C. Quinn
EBioMedicine. 2020 Dec; 62: 103102. Published online 2020 Nov 7. doi: 10.1016/j.ebiom.2020.103102
PMCID:
PMC7658649
AbstractArticlePDF–650K
8.
Racial differences in α4β7 expression on CD4+ T cells of HIV-negative men and women who inject drugs
Alyssa R. Martin, Aida Sivro, Zoe R. Packman, Eshan U. Patel, Livia R. Goes, Lyle R. McKinnon, Jacquie Astemborski, Gregory D. Kirk, Shruti H. Mehta, Claudia Cicala, James Arthos, Andrew D. Redd, Thomas C. Quinn
PLoS One. 2020; 15(8): e0238234. Published online 2020 Aug 25. doi: 10.1371/journal.pone.0238234
PMCID:
PMC7447027
AbstractArticlePDF–734K
9.
Integrin α4β7 expression on peripheral blood CD4+ T cells predicts HIV acquisition and disease progression outcomes
Aida Sivro, Alexandra Schuetz, Daniel Sheward, Vineet Joag, Sergey Yegorov, Lenine J. Liebenberg, Nonhlanhla Yende, Andrew Stalker, Ruth S. Mwatelah, Philippe Selhorst, Nigel Garrett, Natasha Samsunder, Anisha Balgobin, Fatima Nawaz, Claudia Cicala, James Arthos, Anthony S. Fauci, A. Omu Anzala, Joshua Kimani, Bernard S. Bagaya, Noah Kiwanuka, Carolyn Williamson, Rupert Kaul, Jo-Ann S. Passmore, Nittaya Phanuphak, Jintanat Ananworanich, Aftab Ansari, Quarraisha Abdool Karim, Salim S. Abdool Karim, Lyle R. McKinnon
Sci Transl Med. Author manuscript; available in PMC 2019 Oct 30.
Published in final edited form as: Sci Transl Med. 2018 Jan 24; 10(425): eaam6354. doi: 10.1126/scitranslmed.aam6354
PMCID:
PMC6820005
AbstractArticlePDF–1.1M
10.
Perlecan regulates pericyte dynamics in the maintenance and repair of the blood–brain barrier
Kuniyuki Nakamura, Tomoko Ikeuchi, Kazuki Nara, Craig S. Rhodes, Peipei Zhang, Yuta Chiba, Saiko Kazuno, Yoshiki Miura, Tetsuro Ago, Eri Arikawa-Hirasawa, Yoh-suke Mukouyama, Yoshihiko Yamada
J Cell Biol. 2019 Oct 7; 218(10): 3506–3525. Published online 2019 Sep 20. doi: 10.1083/jcb.201807178
PMCID:
PMC6781430
AbstractArticlePDF–5.3M
11.
LncRNAs-directed PTEN enzymatic switch governs epithelial–mesenchymal transition
Qingsong Hu, Chunlai Li, Shouyu Wang, Yajuan Li, Bo Wen, Yanyan Zhang, Ke Liang, Jun Yao, Youqiong Ye, Heidi Hsiao, Tina K. Nguyen, Peter K. Park, Sergey D. Egranov, David H. Hawke, Jeffrey R. Marks, Leng Han, Mien-Chie Hung, Bing Zhang, Chunru Lin, Liuqing Yang
Cell Res. 2019 Apr; 29(4): 286–304. Published online 2019 Jan 10. doi: 10.1038/s41422-018-0134-3
PMCID:
PMC6461864
AbstractArticlePDF–11M
12.
Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development
Hao Sun, Frederic Lagarrigue, Alexandre R. Gingras, Zhichao Fan, Klaus Ley, Mark H. Ginsberg
J Cell Biol. 2018 Apr 2; 217(4): 1453–1465. doi: 10.1083/jcb.201707055
PMCID:
PMC5881498
AbstractArticlePDF–2.1M
13.
Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions
Kyuho Han, Edwin E. Jeng, Gaelen T. Hess, David W. Morgens, Amy Li, Michael C. Bassik
Nat Biotechnol. Author manuscript; available in PMC 2017 Sep 20.
Published in final edited form as: Nat Biotechnol. 2017 May; 35(5): 463–474. Published online 2017 Mar 20. doi: 10.1038/nbt.3834
PMCID:
PMC5557292
AbstractArticlePDF–3.4M
14.
Preferential loss of gut-homing α4β7 CD4+ T cells and their circulating functional subsets in acute HIV-1 infection
Xiaofan Lu, Zhen Li, Qunhui Li, Yanmei Jiao, Yunxia Ji, Hongwei Zhang, Zhuoming Liu, Wei Li, Hao Wu
Cell Mol Immunol. 2016 Nov; 13(6): 776–784. Published online 2015 Aug 17. doi: 10.1038/cmi.2015.60
PMCID:
PMC5101442
AbstractArticlePDF–1.7M
15.
Brief Report: A High Rate of β7+ Gut-Homing Lymphocytes in HIV-Infected Immunological Nonresponders is Associated With Poor CD4 T-Cell Recovery During Suppressive HAART
Alexandre Girard, Delphine Vergnon-Miszczycha, Anne-Emmanuelle Depincé-Berger, Xavier Roblin, Frederic Lutch, Claude Lambert, Nicolas Rochereau, Thomas Bourlet, Christian Genin, Stéphane Paul
J Acquir Immune Defic Syndr. 2016 Jul 1; 72(3): 259–265. Published online 2016 Jun 24. doi: 10.1097/QAI.0000000000000943
PMCID:
PMC4915751
AbstractArticlePDF–610K
16.
Identification of New Regions in HIV-1 gp120 Variable 2 and 3 Loops that Bind to α4β7 Integrin Receptor
Kristina K. Peachman, Nicos Karasavvas, Agnes-Laurence Chenine, Robert McLinden, Supachai Rerks-Ngarm, Kaewkungwal Jaranit, Sorachai Nitayaphan, Punnee Pitisuttithum, Sodsai Tovanabutra, Susan Zolla-Pazner, Nelson L. Michael, Jerome H. Kim, Carl R. Alving, Mangala Rao
PLoS One. 2015; 10(12): e0143895. Published online 2015 Dec 1. doi: 10.1371/journal.pone.0143895
PMCID:
PMC4666614
AbstractArticlePDF–1.2M
17.
Human Blood-Circulating Basophils Capture HIV-1 and Mediate Viral trans-Infection of CD4+ T Cells
Ai-Ping Jiang, Jin-Feng Jiang, Ming-Gao Guo, Yong-Mei Jin, Yu-Ye Li, Jian-Hua Wang
J Virol. 2015 Aug 1; 89(15): 8050–8062. Published online 2015 May 27. doi: 10.1128/JVI.01021-15
PMCID:
PMC4505656
AbstractArticlePDF–3.4M
18.
South African HIV-1 subtype C transmitted variants with a specific V2 motif show higher dependence on α4β7 for replication
Simone I Richardson, Elin S Gray, Nonhlanhla N Mkhize, Daniel J Sheward, Bronwen E Lambson, Constantinos Kurt Wibmer, Lindi Masson, Lise Werner, Nigel Garrett, Jo-Ann S Passmore, Quarraisha Abdool Karim, Salim S Abdool Karim, Carolyn Williamson, Penny L Moore, Lynn Morris
Retrovirology. 2015; 12: 54. Published online 2015 Jun 24. doi: 10.1186/s12977-015-0183-3
PMCID:
PMC4479312
AbstractArticlePDF–4.4M
19.
The Relative Influence of Metal Ion Binding Sites in the I-like Domain and the Interface with the Hybrid Domain on Rolling and Firm Adhesion by Integrin α4β7
JianFeng Chen, Junichi Takagi, Can Xie, Tsan Xiao, Bing-Hao Luo, Timothy A. Springer
J Biol Chem. Author manuscript; available in PMC 2015 Mar 25.
Published in final edited form as: J Biol Chem. 2004 Dec 31; 279(53): 55556–55561. Published online 2004 Sep 24. doi: 10.1074/jbc.M407773200
PMCID:
PMC4373085
AbstractArticlePDF–835K
20.
Cryptic Determinant of α4β7 Binding in the V2 Loop of HIV-1 gp120
Boonrat Tassaneetrithep, Doreen Tivon, James Swetnam, Nicos Karasavvas, Nelson L. Michael, Jerome H. Kim, Mary Marovich, Timothy Cardozo
PLoS One. 2014; 9(9): e108446. Published online 2014 Sep 29. doi: 10.1371/journal.pone.0108446
PMCID:
PMC4180765
AbstractArticlePDF–1.8M

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