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Select item 63222981.

aThe characteristics of glucose metabolism in the sulfonylurea receptor 1 knockout rat model

Xiaojun Zhou, Chunmei Xu, Zhiwei Zou, Xue Shen, Tianyue Xie, Rui Zhang, Lin Liao, Jianjun Dong

Mol Med. 2019; 25: 2. Published online 2019 Jan 7. doi: 10.1186/s10020-018-0067-9

PMCID:: PMC6322298

Abstract Article PDF–10M

Select item 61011962.

A rare mutation in ABCC8/SUR1 leading to altered K_ATP channel activity and β-cell glucose sensing is associated with type 2 diabetes mellitus in adults

Andrei I. Tarasov, Tamara Nicolson, Jean-Pierre Riveline, Tarvinder K. Taneja, Stephen A. Baldwin, Jocelyn M. Baldwin, Guillaume Charpentier, Jean-François Gautier, Philippe Froguel, Martine Vaxillaire, Guy A. Rutter

Diabetes. Author manuscript; available in PMC 2018 Aug 20.

Published in final edited form as: Diabetes. 2008 Jun; 57(6): 1595–1604. Published online 2008 Mar 17. doi: 10.2337/db07-1547

PMCID:: PMC6101196

Abstract Article PDF–1.4M

Select item 56555153.

Conserved functional consequences of disease-associated mutations in the slide helix of Kir6.1 and Kir6.2 subunits of the ATP-sensitive potassium channel

Paige E. Cooper, Conor McClenaghan, Xingyu Chen, Anna Stary-Weinzinger, Colin G. Nichols

J Biol Chem. 2017 Oct 20; 292(42): 17387–17398. Published online 2017 Aug 23. doi: 10.1074/jbc.M117.804971

PMCID:: PMC5655515

Abstract Article PDF–3.2M

Select item 53446704.

Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating

Gregory M Martin, Craig Yoshioka, Emily A Rex, Jonathan F Fay, Qing Xie, Matthew R Whorton, James Z Chen, Show-Ling Shyng

eLife. 2017; 6: e24149. Published online 2017 Jan 16. doi: 10.7554/eLife.24149

PMCID:: PMC5344670

Abstract Article PDF–6.8M

Select item 49990585.

SUR1-Associated Mechanisms Are Not Involved in Ischemic Optic Neuropathy 1 Day Post-Injury

James D. Nicholson, Yan Guo, Steven L. Bernstein

PLoS One. 2016; 11(8): e0148855. Published online 2016 Aug 25. doi: 10.1371/journal.pone.0148855

PMCID:: PMC4999058

Abstract Article PDF–1.6M

Select item 46200326.

Sur1-Trpm4 Cation Channel Expression in Human Cerebral Infarcts

Rupal I. Mehta, Cigdem Tosun, Svetlana Ivanova, Natalia Tsymbalyuk, Bolanle M. Famakin, Min Seong Kwon, Rudy J. Castellani, Volodymyr Gerzanich, J. Marc Simard

J Neuropathol Exp Neurol. Author manuscript; available in PMC 2016 Aug 1.

Published in final edited form as: J Neuropathol Exp Neurol. 2015 Aug; 74(8): 835–849. doi: 10.1097/NEN.0000000000000223

PMCID:: PMC4620032

Abstract Article PDF–1.0M

Select item 46136877.

Molecular determinants of ATP-sensitive potassium channel MgATPase activity: diabetes risk variants and diazoxide sensitivity

Mohammad Fatehi, Chris R.J. Carter, Nermeen Youssef, Beth E. Hunter, Andrew Holt, Peter E. Light

Biosci Rep. 2015 Aug; 35(4): e00238. Prepublished online 2015 Jul 7. Published online 2015 Aug 18. doi: 10.1042/BSR20150143

PMCID:: PMC4613687

Abstract Article PDF–1.2M

Select item 44101728.

ATP-sensitive potassium channels modulate in vitro tocolytic effects of β₂-AR agonists on uterine muscle rings in rats in early but not in late pregnancy

Norbert Lovasz, Andrea Koncz, Dora Domokos, Robert Gaspar, György Falkay

Croat Med J. 2015 Apr; 56(2): 114–118. doi: 10.3325/cmj.2015.56.114

PMCID:: PMC4410172

Abstract Article PDF–397K

Select item 42294859.

Monoallelic ABCC8 mutations are a common cause of diazoxide-unresponsive diffuse form of congenital hyperinsulinism

Cécile Saint-Martin, Qing Zhou, Gregory M. Martin, Christelle Vaury, Gwendoline Leroy, Jean-Baptiste Arnoux, Pascale de Lonlay, Show-Ling Shyng, Christine Bellanné-Chantelot

Clin Genet. Author manuscript; available in PMC 2016 May 1.

Published in final edited form as: Clin Genet. 2015 May; 87(5): 448–454. Published online 2014 Jun 6. doi: 10.1111/cge.12428

PMCID:: PMC4229485

Abstract Article PDF–279K

Select item 393767010.

Phosphatidylinositol 4,5-Biphosphate (PIP₂) Modulates Interaction of Syntaxin-1A with Sulfonylurea Receptor 1 to Regulate Pancreatic β-Cell ATP-sensitive Potassium Channels

Tao Liang, Li Xie, Christin Chao, Youhou Kang, Xianguang Lin, Tairan Qin, Huanli Xie, Zhong-Ping Feng, Herbert Y. Gaisano

J Biol Chem. 2014 Feb 28; 289(9): 6028–6040. Published online 2014 Jan 15. doi: 10.1074/jbc.M113.511808

PMCID:: PMC3937670

Abstract Article PDF–2.6M

Select item 389485511.

Inhibition of the Sur1-Trpm4 Channel Reduces Neuroinflammation and Cognitive Impairment in Subarachnoid Hemorrhage

Cigdem Tosun, David B. Kurland, Rupal Mehta, Rudy J. Castellani, Joyce L. deJong, Min Seong Kwon, Seung Kyoon Woo, Volodymyr Gerzanich, J. Marc Simard

Stroke. Author manuscript; available in PMC 2014 Jan 17.

Published in final edited form as: Stroke. 2013 Dec; 44(12): 3522–3528. Published online 2013 Oct 10. doi: 10.1161/STROKEAHA.113.002904

PMCID:: PMC3894855

Abstract Article PDF–4.4M

Select item 363835612.

Inhibition of SUR1 Decreases the Vascular Permeability of Cerebral Metastases

Eric M Thompson, Gregory L Pishko, Leslie L Muldoon, Edward A Neuwelt

Neoplasia. 2013 May; 15(5): 535–543. doi: 10.1593/neo.13164

PMCID:: PMC3638356

Abstract Article PDF–2.1M

Select item 358780513.

Glibenclamide enhances neurogenesis and improves long-term functional recovery after transient focal cerebral ischemia

Francisco J Ortega, Jukka Jolkkonen, Nicole Mahy, Manuel J Rodríguez

J Cereb Blood Flow Metab. 2013 Mar; 33(3): 356–364. Published online 2012 Nov 14. doi: 10.1038/jcbfm.2012.166

PMCID:: PMC3587805

Abstract Article PDF–649K

Select item 356158314.

The Sulfonylurea Receptor 1 (Sur1)-Transient Receptor Potential Melastatin 4 (Trpm4) Channel

Seung Kyoon Woo, Min Seong Kwon, Alexander Ivanov, Volodymyr Gerzanich, J. Marc Simard

J Biol Chem. 2013 Feb 1; 288(5): 3655–3667. Published online 2012 Dec 19. doi: 10.1074/jbc.M112.428219

PMCID:: PMC3561583

Abstract Article PDF–3.3M

Select item 349529815.

A universally conserved residue in the SUR1 subunit of the K_ATP channel is essential for translating nucleotide binding at SUR1 into channel opening

Heidi de Wet, Kenju Shimomura, Jussi Aittoniemi, Nawaz Ahmad, Mathilde Lafond, Mark SP Sansom, Frances M Ashcroft

J Physiol. 2012 Oct 15; 590(Pt 20): 5025–5036. Published online 2012 Jul 16. doi: 10.1113/jphysiol.2012.236075

PMCID:: PMC3495298

Abstract Article PDF–1.3M

Select item 337547616.

Dominantly acting ABCC8 mutations in patients with medically unresponsive hyperinsulinaemic hypoglycaemia

SE Flanagan, RR Kapoor, I Banerjee, C Hall, VV Smith, K Hussain, S Ellard

Clin Genet. 2011 Jun; 79(6): 582–587. doi: 10.1111/j.1399-0004.2010.01476.x

PMCID:: PMC3375476

Abstract Article PDF–557K

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 312309618.

Syntaxin-1A Interacts with Distinct Domains within Nucleotide-binding Folds of Sulfonylurea Receptor 1 to Inhibit β-Cell ATP-sensitive Potassium Channels

Nathan Chang, Tao Liang, Xianguang Lin, Youhou Kang, Huanli Xie, Zhong-Ping Feng, Herbert Y. Gaisano

J Biol Chem. 2011 Jul 1; 286(26): 23308–23318. Published online 2011 May 3. doi: 10.1074/jbc.M111.217950

PMCID:: PMC3123096

Abstract Article PDF–2.2M

Select item 303770019.

ATP Modulates Interaction of Syntaxin-1A with Sulfonylurea Receptor 1 to Regulate Pancreatic β-Cell K_ATP Channels

Youhou Kang, Yi Zhang, Tao Liang, Yuk-Man Leung, Betty Ng, Huanli Xie, Nathan Chang, Joseph Chan, Show-Ling Shyng, Robert G. Tsushima, Herbert Y. Gaisano

J Biol Chem. 2011 Feb 18; 286(7): 5876–5883. Published online 2010 Dec 20. doi: 10.1074/jbc.M109.089607