PMC Links for GEO Profiles (Select 62653005) - PMC

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Items: 19

Select item 91196751.

Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects

Maja Solman, Sasja Blokzijl-Franke, Florian Piques, Chuan Yan, Qiqi Yang, Marion Strullu, Sarah M Kamel, Pakize Ak, Jeroen Bakkers, David M Langenau, Hélène Cavé, Jeroen den Hertog

eLife. 2022; 11: e73040. Published online 2022 May 10. doi: 10.7554/eLife.73040

PMCID:: PMC9119675

Abstract Article PDF–5.2M

Select item 57890282.

Shp2–Mitogen-Activated Protein Kinase Signaling Drives Proliferation during Zebrafish Embryo Caudal Fin Fold Regeneration

Alexander James Hale, Jeroen den Hertog

Mol Cell Biol. 2018 Feb 15; 38(4): e00515-17. Prepublished online 2017 Dec 4. Published online 2018 Jan 29. doi: 10.1128/MCB.00515-17

PMCID:: PMC5789028

Abstract Article PDF–3.6M

Select item 57839633.

The Protein Tyrosine Phosphatase Shp2 Regulates Oligodendrocyte Differentiation and Early Myelination and Contributes to Timely Remyelination

Jared T. Ahrendsen, Danielle E. Harlow, Lisbet T. Finseth, Jennifer N. Bourne, Sean P. Hickey, Elizabeth A. Gould, Cecilia M. Culp, Wendy B. Macklin

J Neurosci. 2018 Jan 24; 38(4): 787–802. doi: 10.1523/JNEUROSCI.2864-16.2017

PMCID:: PMC5783963

Abstract Article PDF–8.5M

Select item 55596104.

Differential oxidation of protein-tyrosine phosphatases during zebrafish caudal fin regeneration

Wei Wu, Alexander James Hale, Simone Lemeer, Jeroen den Hertog

Sci Rep. 2017; 7: 8460. Published online 2017 Aug 16. doi: 10.1038/s41598-017-07109-8

PMCID:: PMC5559610

Abstract Article PDF–2.9M

Select item 53930485.

Critical Role for GAB2 in Neuroblastoma Pathogenesis Through the Promotion of SHP2/MYCN Cooperation

Xiaoling Zhang, Zhiwei Dong, Cheng Zhang, Choong Yong Ung, Shuning He, Ting Tao, Andre M. Oliveira, Alexander Meves, Baoan Ji, A. Thomas Look, Hu Li, Benjamin G. Neel, Shizhen Zhu

Cell Rep. Author manuscript; available in PMC 2017 Apr 17.

Published in final edited form as: Cell Rep. 2017 Mar 21; 18(12): 2932–2942. doi: 10.1016/j.celrep.2017.02.065

PMCID:: PMC5393048

Abstract Article PDF–1.8M

Select item 52784226.

Utilising polymorphisms to achieve allele-specific genome editing in zebrafish

Samuel J. Capon, Gregory J. Baillie, Neil I. Bower, Jason A. da Silva, Scott Paterson, Benjamin M. Hogan, Cas Simons, Kelly A. Smith

Biol Open. 2017 Jan 15; 6(1): 125–131. Published online 2016 Nov 28. doi: 10.1242/bio.020974

PMCID:: PMC5278422

Abstract Article PDF–2.0M

Select item 46341377.

RFX transcription factors are essential for hearing in mice

Ran Elkon, Beatrice Milon, Laura Morrison, Manan Shah, Sarath Vijayakumar, Manoj Racherla, Carmen C. Leitch, Lorna Silipino, Shadan Hadi, Michèle Weiss-Gayet, Emmanuèle Barras, Christoph D. Schmid, Aouatef Ait-Lounis, Ashley Barnes, Yang Song, David J. Eisenman, Efrat Eliyahu, Gregory I. Frolenkov, Scott E. Strome, Bénédicte Durand, Norann A. Zaghloul, Sherri M. Jones, Walter Reith, Ronna Hertzano

Nat Commun. 2015; 6: 8549. Published online 2015 Oct 15. doi: 10.1038/ncomms9549

PMCID:: PMC4634137

Abstract Article PDF–5.5M

Select item 43267118.

Heterozygous germline mutations in A2ML1 are associated with a disorder clinically related to Noonan syndrome

Lisenka ELM Vissers, Monica Bonetti, Jeroen Paardekooper Overman, Willy M Nillesen, Suzanna G M Frints, Joep de Ligt, Giuseppe Zampino, Ana Justino, José C Machado, Marga Schepens, Han G Brunner, Joris A Veltman, Hans Scheffer, Piet Gros, José L Costa, Marco Tartaglia, Ineke van der Burgt, Helger G Yntema, Jeroen den Hertog

Eur J Hum Genet. 2015 Mar; 23(3): 317–324. Published online 2014 Jun 18. doi: 10.1038/ejhg.2014.115

PMCID:: PMC4326711

Abstract Article PDF–1.3M

Select item 41536549.

Phosphoproteomics-Mediated Identification of Fer Kinase as a Target of Mutant Shp2 in Noonan and LEOPARD Syndrome

Jeroen Paardekooper Overman, Christian Preisinger, Karin Prummel, Monica Bonetti, Piero Giansanti, Albert Heck, Jeroen den Hertog

PLoS One. 2014; 9(9): e106682. Published online 2014 Sep 3. doi: 10.1371/journal.pone.0106682

PMCID:: PMC4153654

Abstract Article PDF–12M

Select item 413557210.

PZR Coordinates Shp2 Noonan and LEOPARD Syndrome Signaling in Zebrafish and Mice

Jeroen Paardekooper Overman, Jae-Sung Yi, Monica Bonetti, Matthew Soulsby, Christian Preisinger, Matthew P. Stokes, Li Hui, Jeffrey C. Silva, John Overvoorde, Piero Giansanti, Albert J. R. Heck, Maria I. Kontaridis, Jeroen den Hertog, Anton M. Bennett

Mol Cell Biol. 2014 Aug; 34(15): 2874–2889. doi: 10.1128/MCB.00135-14

PMCID:: PMC4135572

Abstract Article PDF–4.0M

Select item 399243711.

Clonal evolution enhances leukemia propagating cell frequency in T-cell acute lymphoblastic leukemia through Akt/mTORC1 pathway activation

Jessica S. Blackburn, Sali Liu, Jayme L. Wilder, Kimberly P. Dobrinski, Riadh Lobbardi, Finola E. Moore, Sarah A. Martinez, Eleanor Y. Chen, Charles Lee, David M. Langenau

Cancer Cell. Author manuscript; available in PMC 2015 Mar 17.

Published in final edited form as: Cancer Cell. 2014 Mar 17; 25(3): 366–378. Published online 2014 Mar 6. doi: 10.1016/j.ccr.2014.01.032

PMCID:: PMC3992437

Abstract Article PDF–1.4M

Select item 398809912.

Distinct and Overlapping Functions of ptpn11 Genes in Zebrafish Development

Monica Bonetti, Virginia Rodriguez-Martinez, Jeroen Paardekooper Overman, John Overvoorde, Mark van Eekelen, Chris Jopling, Jeroen den Hertog

PLoS One. 2014; 9(4): e94884. Published online 2014 Apr 15. doi: 10.1371/journal.pone.0094884

PMCID:: PMC3988099

Abstract Article PDF–1.3M

Select item 393145313.

From zebrafish heart jogging genes to mouse and human orthologs: using Gene Ontology to investigate mammalian heart development.

Varsha K Khodiyar, Doug Howe, Philippa J Talmud, Ross Breckenridge, Ruth C Lovering

Version 2. F1000Res. 2013; 2: 242. Published online 2014 Feb 10. doi: 10.12688/f1000research.2-242.v2

PMCID:: PMC3931453

Abstract Article PDF–957K

Select item 329674414.

Evolution of JAK-STAT Pathway Components: Mechanisms and Role in Immune System Development

Clifford Liongue, Lynda A. O'Sullivan, Monique C. Trengove, Alister C. Ward

PLoS One. 2012; 7(3): e32777. Published online 2012 Mar 7. doi: 10.1371/journal.pone.0032777

PMCID:: PMC3296744

Abstract Article PDF–1.5M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 303515416.

Phosphatase-dependent and -independent Functions of Shp2 in Neural Crest Cells Underlie LEOPARD Syndrome Pathogenesis

Rodney A. Stewart, Takaomi Sanda, Hans R. Widlund, Shizhen Zhu, Kenneth D. Swanson, Aeron D. Hurley, Mohamed Bentires-Alj, David E. Fisher, Maria I. Kontaridis, A. Thomas Look, Benjamin G. Neel

Dev Cell. Author manuscript; available in PMC 2011 May 18.

Published in final edited form as: Dev Cell. 2010 May 18; 18(5): 750–762. doi: 10.1016/j.devcel.2010.03.009