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Select item 109416581.

The neuronal transcription factor MEIS2 is a calpain-2 protease target

Tanja Müller, Marina Reichlmeir, Ann-Christin Hau, Ilka Wittig, Dorothea Schulte

J Cell Sci. 2024 Feb 15; 137(4): jcs261482. Published online 2024 Feb 28. doi: 10.1242/jcs.261482

PMCID:: PMC10941658

Abstract Article

Select item 108298712.

Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors

Yiting Wang, Yufan Sun, Shouyan Deng, Jiayang Liu, Jianghong Yu, Hao Chi, Xue Han, Yuan Zhang, Jiawei Shi, Yungang Wang, Yingfei Quan, Hai Li, Jie Xu

Cell Rep Med. 2024 Jan 16; 5(1): 101374. Published online 2024 Jan 16. doi: 10.1016/j.xcrm.2023.101374

PMCID:: PMC10829871

Abstract Article PDF–8.2M

Select item 103250923.

Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens

Huntly M. Morrison, Julia Craft, Rafael Rivera-Lugo, Jeffery R. Johnson, Guillaume R. Golovkine, Samantha L. Bell, Claire E. Dodd, Erik Van Dis, Wandy L. Beatty, Shally R. Margolis, Teresa Repasy, Isaac Shaker, Angus Y. Lee, Russell E. Vance, Sarah A. Stanley, Robert O. Watson, Nevan J. Krogan, Daniel A. Portnoy, Bennett H. Penn, Jeffery S. Cox

PLoS Pathog. 2023 Jun; 19(6): e1011088. Published online 2023 Jun 23. doi: 10.1371/journal.ppat.1011088

PMCID:: PMC10325092

Abstract Article PDF–1.6M

Select item 98981644.

Galectin-8 downmodulates TLR4 activation and impairs bacterial clearance in a mouse model of Pseudomonas keratitis

Abdulraouf Ramadan, Zhiyi Cao, Mujtaba Hassan, Fredrik Zetterberg, Ulf J. Nilsson, Mihaela Gadjeva, Vijay Rathinam, Noorjahan Panjwani

J Immunol. Author manuscript; available in PMC 2024 Feb 15.

Published in final edited form as: J Immunol. 2023 Feb 15; 210(4): 398–407. doi: 10.4049/jimmunol.2200706

PMCID:: PMC9898164

Abstract Article PDF–890K

Select item 97246575.

The AAA‐ATPase ATAD1 and its partners promote degradation of desmin intermediate filaments in muscle

Dina Aweida, Shenhav Cohen

EMBO Rep. 2022 Dec; 23(12): e55175. Published online 2022 Oct 24. doi: 10.15252/embr.202255175

PMCID:: PMC9724657

Abstract Article PDF–3.0M

Select item 92334396.

Calpain-2 Mediates MBNL2 Degradation and a Developmental RNA Processing Program in Neurodegeneration

Lee-Hsin Wang, Chien-Yu Lin, Yu-Mei Lin, Luc Buée, Nicolas Sergeant, David Blum, Yijuang Chern, Guey-Shin Wang

J Neurosci. 2022 Jun 22; 42(25): 5102–5114. doi: 10.1523/JNEUROSCI.2006-21.2022

PMCID:: PMC9233439

Abstract Article PDF–3.5M

Select item 90585447.

Endosomal phosphatidylinositol 3‐phosphate controls synaptic vesicle cycling and neurotransmission

Guan‐Ting Liu, Gaga Kochlamazashvili, Dmytro Puchkov, Rainer Müller, Carsten Schultz, Albert I Mackintosh, Dennis Vollweiter, Volker Haucke, Tolga Soykan

EMBO J. 2022 May; 41(9): e109352. Published online 2022 Mar 22. doi: 10.15252/embj.2021109352

PMCID:: PMC9058544

Abstract Article PDF–4.6M

Select item 85284288.

Computational repurposing of therapeutic small molecules from cancer to pulmonary hypertension

Vinny Negi, Jimin Yang, Gil Speyer, Andres Pulgarin, Adam Handen, Jingsi Zhao, Yi Yin Tai, Ying Tang, Miranda K. Culley, Qiujun Yu, Patricia Forsythe, Anastasia Gorelova, Annie M. Watson, Yassmin Al Aaraj, Taijyu Satoh, Maryam Sharifi-Sanjani, Arun Rajaratnam, John Sembrat, Steeve Provencher, Xianglin Yin, Sara O. Vargas, Mauricio Rojas, Sébastien Bonnet, Stephanie Torrino, Bridget K. Wagner, Stuart L. Schreiber, Mingji Dai, Thomas Bertero, Imad Al Ghouleh, Seungchan Kim, Stephen Y. Chan

Sci Adv. 2021 Oct; 7(43): eabh3794. Published online 2021 Oct 20. doi: 10.1126/sciadv.abh3794

PMCID:: PMC8528428

Abstract Article PDF–2.1M

Select item 84063269.

Galectin-8 Senses Phagosomal Damage and Recruits Selective Autophagy Adapter TAX1BP1 To Control Mycobacterium tuberculosis Infection in Macrophages

Samantha L. Bell, Kayla L. Lopez, Jeffery S. Cox, Kristin L. Patrick, Robert O. Watson

mBio. 2021 Jul-Aug; 12(4): e01871-20. Published online 2021 Jul 6. doi: 10.1128/mBio.01871-20

PMCID:: PMC8406326

Abstract Article PDF–8.5M

Select item 820042310.

Autoantibody of NRIP, a novel AChR‐interacting protein, plays a detrimental role in myasthenia gravis

Li‐Kai Tsai, I‐Hsin Chen, Chi‐Chao Chao, Hsueh‐Wen Hsueh, Hsin‐Hsiung Chen, Yun‐Hsin Huang, Rong‐Wei Weng, Tzu‐Yun Lai, Yi‐Chieh Tsai, Yeou‐Ping Tsao, Show‐Li Chen

J Cachexia Sarcopenia Muscle. 2021 Jun; 12(3): 665–676. Published online 2021 Mar 26. doi: 10.1002/jcsm.12697

PMCID:: PMC8200423

Abstract Article PDF–11M

Select item 806230711.

Inducible Depletion of Calpain-2 Mitigates Abdominal Aortic Aneurysm in Mice

Latha Muniappan, Michihiro Okuyama, Aida Javidan, Devi Thiagarajan, Weihua Jiang, Jessica J. Moorleghen, Lihua Yang, Anju Balakrishnan, Deborah A. Howatt, Haruhito A. Uchida, Takaomi C. Saido, Venkateswaran Subramanian

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2022 May 5.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2021 May 5; 41(5): 1694–1709. Published online 2021 Mar 25. doi: 10.1161/ATVBAHA.120.315546

PMCID:: PMC8062307

Abstract Article PDF–2.6M

Select item 793877012.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 782026113.

A new mouse model for retinal degeneration due to Fam161a deficiency

Avigail Beryozkin, Chen Matsevich, Alexey Obolensky, Corinne Kostic, Yvan Arsenijevic, Uwe Wolfrum, Eyal Banin, Dror Sharon

Sci Rep. 2021; 11: 2030. Published online 2021 Jan 21. doi: 10.1038/s41598-021-81414-1

PMCID:: PMC7820261

Abstract Article PDF–3.3M

Select item 761663014.

Podoplanin-expressing macrophages promote lymphangiogenesis and lymphoinvasion via Galectin 8-mediated adhesion to tumor lymphatics

Paweł Bieniasz-Krzywiec, Rosa Martín-Pérez, Manuel Ehling, Melissa García-Caballero, Sotiria Pinioti, Samantha Pretto, Roel Kroes, Chiara Aldeni, Mario Di Matteo, Hans Prenen, María Virginia Tribulatti, Oscar Campetella, Ann Smeets, Agnes Noel, Giuseppe Floris, Jo A. Van Ginderachter, Massimiliano Mazzone

Cell Metab. Author manuscript; available in PMC 2024 Sep 24.

Published in final edited form as: Cell Metab. 2019 Nov 5; 30(5): 917–936.e10. Published online 2019 Aug 22. doi: 10.1016/j.cmet.2019.07.015

PMCID:: PMC7616630

Abstract Article PDF–3.4M

Select item 745846615.

Calpain-2 as a therapeutic target in repeated concussion–induced neuropathy and behavioral impairment

Yubin Wang, Yan Liu, Amy Nham, Arash Sherbaf, Diana Quach, Emad Yahya, Davis Ranburger, Xiaoning Bi, Michel Baudry

Sci Adv. 2020 Jul; 6(27): eaba5547. Published online 2020 Jul 1. doi: 10.1126/sciadv.aba5547

PMCID:: PMC7458466

Abstract Article PDF–3.5M

Select item 741599116.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 734384917.

Anti-inflammatory Role of Galectin-8 During Trypanosoma cruzi Chronic Infection

Adriano Bertelli, Liliana M. Sanmarco, Carla A. Pascuale, Miriam Postan, Maria P. Aoki, María S. Leguizamón

Front Cell Infect Microbiol. 2020; 10: 285. Published online 2020 Jul 2. doi: 10.3389/fcimb.2020.00285

PMCID:: PMC7343849

Abstract Article PDF–3.7M

Select item 733437618.

Galectin-8 Enhances T cell Response by Promotion of Antigen Internalization and Processing

Cecilia Arahí Prato, Julieta Carabelli, Oscar Campetella, María Virginia Tribulatti

iScience. 2020 Jul 24; 23(7): 101278. Published online 2020 Jun 17. doi: 10.1016/j.isci.2020.101278

PMCID:: PMC7334376

Abstract Article PDF–7.1M

Select item 719359419.

The Animal Lectin Galectin-8 Promotes Cytokine Expression and Metastatic Tumor Growth in Mice

Hadas Shatz-Azoulay, Yaron Vinik, Roi Isaac, Ulrike Kohler, Sima Lev, Yehiel Zick

Sci Rep. 2020; 10: 7375. Published online 2020 Apr 30. doi: 10.1038/s41598-020-64371-z

PMCID:: PMC7193594

Abstract Article PDF–3.9M

Select item 630254720.

Galectin-8 Favors the Presentation of Surface-Tethered Antigens by Stabilizing the B Cell Immune Synapse

Dorian Obino, Luc Fetler, Andrea Soza, Odile Malbec, Juan José Saez, Mariana Labarca, Claudia Oyanadel, Felipe Del Valle Batalla, Nicolas Goles, Aleksandra Chikina, Danielle Lankar, Fabián Segovia-Miranda, Camille Garcia, Thibaut Léger, Alfonso Gonzalez, Marion Espéli, Ana-Maria Lennon-Duménil, Maria-Isabel Yuseff

Cell Rep. 2018 Dec 11; 25(11): 3110–3122.e6. Published online 2018 Dec 11. doi: 10.1016/j.celrep.2018.11.052

PMCID:: PMC6302547

Abstract Article

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