PMC Links for GEO Profiles (Select 62572190) - PMC

Select item 90325221.

Cysteine-Rich LIM-Only Protein 4 (CRP4) Promotes Atherogenesis in the ApoE^−/− Mouse Model

Natalie Längst, Julia Adler, Anna Kuret, Andreas Peter, Peter Ruth, Karsten Boldt, Robert Lukowski

Cells. 2022 Apr; 11(8): 1364. Published online 2022 Apr 17. doi: 10.3390/cells11081364

PMCID:: PMC9032522

Select item 88944892.

Changes to gut amino acid transporters and microbiome associated with increased E/I ratio in Chd8^+/− mouse model of ASD-like behavior

You Yu, Bing Zhang, Peifeng Ji, Zhenqiang Zuo, Yongxi Huang, Ning Wang, Chang Liu, Shuang-Jiang Liu, Fangqing Zhao

Nat Commun. 2022; 13: 1151. Published online 2022 Mar 3. doi: 10.1038/s41467-022-28746-2

PMCID:: PMC8894489

Abstract Article PDF–3.1M

Select item 85706913.

IFN-γ mediates Paneth cell death via suppression of mTOR

Alessandra Araujo, Alexandra Safronova, Elise Burger, Américo López-Yglesias, Shilpi Giri, Ellie T Camanzo, Andrew T Martin, Sergei Grivennikov, Felix Yarovinsky

eLife. 2021; 10: e60478. Published online 2021 Oct 11. doi: 10.7554/eLife.60478

PMCID:: PMC8570691

Abstract Article PDF–14M

Select item 81924974.

Western Diet Induces Paneth Cell Defects through Microbiome Alterations and Farnesoid X Receptor and Type I Interferon Activation

Ta-Chiang Liu, Justin T. Kern, Umang Jain, Naomi M. Sonnek, Shanshan Xiong, Katherine F. Simpson, Kelli L. VanDussen, Emma S. Winkler, Talin Haritunians, Atika Malique, Qiuhe Lu, Yo Sasaki, Chad Storer, Michael S. Diamond, Richard D. Head, Dermot P.B. McGovern, Thaddeus S. Stappenbeck

Cell Host Microbe. Author manuscript; available in PMC 2022 Jun 9.

Published in final edited form as: Cell Host Microbe. 2021 Jun 9; 29(6): 988–1001.e6. Published online 2021 May 18. doi: 10.1016/j.chom.2021.04.004

PMCID:: PMC8192497

Abstract Article PDF–1.9M

Select item 77727745.

Paneth cell–derived growth factors support tumorigenesis in the small intestine

Qing Chen, Kohei Suzuki, Luis Sifuentes-Dominguez, Naoteru Miyata, Jie Song, Adam Lopez, Petro Starokadomskyy, Purva Gopal, Igor Dozmorov, Shuai Tan, Bujun Ge, Ezra Burstein

Life Sci Alliance. 2021 Mar; 4(3): e202000934. Published online 2020 Dec 28. doi: 10.26508/lsa.202000934

PMCID:: PMC7772774

Abstract Article PDF–3.1M

Select item 73329816.

LGR5 controls extracellular matrix production by stem cells in the developing intestine

Valeria Fernandez Vallone, Morgane Leprovots, Didac Ribatallada‐Soriano, Romain Gerbier, Anne Lefort, Frédérick Libert, Gilbert Vassart, Marie‐Isabelle Garcia

EMBO Rep. 2020 Jul 3; 21(7): e49224. Published online 2020 May 28. doi: 10.15252/embr.201949224

PMCID:: PMC7332981

Abstract Article PDF–7.1M

Select item 61794457.

Loss of Paneth cell autophagy causes acute susceptibility to Toxoplasma gondii-mediated inflammation

Elise Burger, Alessandra Araujo, Américo López-Yglesias, Michael W. Rajala, Linda Geng, Beth Levine, Lora V. Hooper, Ezra Burstein, Felix Yarovinsky

Cell Host Microbe. Author manuscript; available in PMC 2019 Feb 14.

Published in final edited form as: Cell Host Microbe. 2018 Feb 14; 23(2): 177–190.e4. Published online 2018 Jan 18. doi: 10.1016/j.chom.2018.01.001

PMCID:: PMC6179445

Abstract Article PDF–1.1M

Select item 32368168.

Biosynthesis and antimicrobial evaluation of backbone-cyclized alpha-defensins^#

Angie E. Garcia, Kenneth P. Tai, Shadakshara S. Puttamadappa, Alexander Shekhtman, Andre J. Ouellette, Julio A. Camarero

Biochemistry. Author manuscript; available in PMC 2012 Dec 6.

Published in final edited form as: Biochemistry. 2011 Dec 6; 50(48): 10508–10519. Published online 2011 Nov 9. doi: 10.1021/bi201430f

PMCID:: PMC3236816

Abstract Article PDF–1.9M

Select item 31780599.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 312827310.

Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo

Roxana C Mustata, Tom Van Loy, Anne Lefort, Frédérick Libert, Sandra Strollo, Gilbert Vassart, Marie-Isabelle Garcia

EMBO Rep. 2011 Jun; 12(6): 558–564. Published online 2011 Apr 21. doi: 10.1038/embor.2011.52

PMCID:: PMC3128273

Abstract Article PDF–1.5M

Select item 301990611.

Strain-Specific Polymorphisms in Paneth Cell α-Defensins of C57BL/6 Mice and Evidence of Vestigial Myeloid α-Defensin Pseudogenes

Michael T. Shanahan, Hiroki Tanabe, André J. Ouellette

Infect Immun. 2011 Jan; 79(1): 459–473. Published online 2010 Nov 1. doi: 10.1128/IAI.00996-10

PMCID:: PMC3019906

Abstract Article PDF–4.3M

Select item 284419712.

Elevated Expression of Paneth Cell CRS4C in Ileitis-prone SAMP1/YitFc Mice: REGIONAL DISTRIBUTION, SUBCELLULAR LOCALIZATION, AND MECHANISM OF ACTION

Michael T. Shanahan, Alda Vidrich, Yoshinori Shirafuji, Claire L. Dubois, Agnes Henschen-Edman, Susan J. Hagen, Steven M. Cohn, André J. Ouellette

J Biol Chem. 2010 Mar 5; 285(10): 7493–7504. Published online 2010 Jan 7. doi: 10.1074/jbc.M109.083220

PMCID:: PMC2844197

Abstract Article PDF–1.9M

Select item 277254613.

Electropositive Charge in α-Defensin Bactericidal Activity: Functional Effects of Lys-for-Arg Substitutions Vary with the Peptide Primary Structure

R. Alan Llenado, Colby S. Weeks, Melanie J. Cocco, André J. Ouellette

Infect Immun. 2009 Nov; 77(11): 5035–5043. Published online 2009 Sep 8. doi: 10.1128/IAI.00695-09

PMCID:: PMC2772546

Abstract Article PDF–1.7M

Select item 264593914.

Mechanisms of α-defensin bactericidal action: COMPARATIVE MEMBRANE DISRUPTION BY CRYPTDIN-4 AND ITS DISULFIDE-NULL ANALOG

Chrystalleni Hadjicharalambous, Tanya Sheynis, Raz Jelinek, Michael T. Shanahan, Andre J. Ouellette, Electra Gizeli

Biochemistry. Author manuscript; available in PMC 2009 Nov 25.

Published in final edited form as: Biochemistry. 2008 Nov 25; 47(47): 12626–12634. doi: 10.1021/bi800335e

PMCID:: PMC2645939

Abstract Article PDF–892K

Select item 228956915.

Enteric defensins: antibiotic peptide components of intestinal host defense

J Cell Biol. 1992 Aug 2; 118(4): 929–936. doi: 10.1083/jcb.118.4.929

PMCID:: PMC2289569

Summary PDF–4.0M

Select item 30322416.

Mouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms.

A J Ouellette, M M Hsieh, M T Nosek, D F Cano-Gauci, K M Huttner, R N Buick, M E Selsted

Infect Immun. 1994 Nov; 62(11): 5040–5047. doi: 10.1128/iai.62.11.5040-5047.1994

PMCID:: PMC303224

Summary Page Browse PDF–1.7M

Select item 13924117.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

Select item 9707818.

Peptide Localization and Gene Structure of Cryptdin 4, a Differentially Expressed Mouse Paneth Cell α-Defensin

Andre J. Ouellette, Dalila Darmoul, Dat Tran, Kenneth M. Huttner, Jun Yuan, Michael E. Selsted

Infect Immun. 1999 Dec; 67(12): 6643–6651. doi: 10.1128/iai.67.12.6643-6651.1999

PMCID:: PMC97078

Abstract Article PDF–1.6M

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