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Items: 1 to 20 of 29

1.
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome
Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh
Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5
PMCID:
PMC10208958
AbstractArticlePDF–7.0M
2.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
3.
An unexpected 2-histidine phosphoesterase activity of suppressor of T-cell receptor signaling protein 1 contributes to the suppression of cell signaling
Yue Yin, David Frank, Weijie Zhou, Neena Kaur, Jarrod B. French, Nick Carpino
J Biol Chem. 2020 Jun 19; 295(25): 8514–8523. Published online 2020 May 5. doi: 10.1074/jbc.RA120.013482
PMCID:
PMC7307200
AbstractArticlePDF–1.5M
4.
LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow
Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher
J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214
PMCID:
PMC6262777
AbstractArticle
5.
Phagocytes from Mice Lacking the Sts Phosphatases Have an Enhanced Antifungal Response to Candida albicans
David Frank, Shamoon Naseem, Gian Luigi Russo, Cindy Li, Kaustubh Parashar, James B. Konopka, Nick Carpino
mBio. 2018 Jul-Aug; 9(4): e00782-18. Published online 2018 Jul 17. doi: 10.1128/mBio.00782-18
PMCID:
PMC6050958
AbstractArticlePDF–2.1M
6.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
7.
TULA-2 Protein Phosphatase Suppresses Activation of Syk through the GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr(P)346, a Regulatory Site of Syk
Kevin Reppschläger, Jeanne Gosselin, Carol A. Dangelmaier, Dafydd H. Thomas, Nick Carpino, Steven E. McKenzie, Satya P. Kunapuli, Alexander Y. Tsygankov
J Biol Chem. 2016 Oct 21; 291(43): 22427–22441. Published online 2016 Sep 8. doi: 10.1074/jbc.M116.743732
Correction in:
J Biol Chem. 2017 Mar 10; 292(10): 4360.
PMCID:
PMC5077183
AbstractArticlePDF–3.2M
8.
The Phosphatases STS1 and STS2 Regulate Hematopoietic Stem and Progenitor Cell Fitness
Jing Zhang, Olesya Vakhrusheva, Srinivasa Rao Bandi, Özlem Demirel, Julhash U. Kazi, Ramona Gomes Fernandes, Katja Jakobi, Astrid Eichler, Lars Rönnstrand, Michael A. Rieger, Nick Carpino, Hubert Serve, Christian H. Brandts
Stem Cell Reports. 2015 Oct 13; 5(4): 633–646. Published online 2015 Sep 10. doi: 10.1016/j.stemcr.2015.08.006
PMCID:
PMC4624938
AbstractArticlePDF–2.6M
9.
Insights into the suppressor of T-cell receptor (TCR) signaling-1 (Sts-1)-mediated regulation of TCR signaling through the use of novel substrate-trapping Sts-1 phosphatase variants
Boris San Luis, Nick Carpino
FEBS J. Author manuscript; available in PMC 2014 Mar 28.
Published in final edited form as: FEBS J. 2014 Feb; 281(3): 696–707. Published online 2013 Dec 12. doi: 10.1111/febs.12615
PMCID:
PMC3968691
AbstractArticlePDF–3.1M
10.
Enhanced Response of T Cells from Murine Gammaherpesvirus 68-Infected Mice Lacking the Suppressor of T Cell Receptor Signaling Molecules Sts-1 and Sts-2
Brandon Cieniewicz, Nicholas Carpino, Laurie T. Krug
PLoS One. 2014; 9(2): e90196. Published online 2014 Feb 28. doi: 10.1371/journal.pone.0090196
PMCID:
PMC3938662
AbstractArticlePDF–1.6M
11.
Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates
Jeremy A. Miller, Jason Nathanson, Daniel Franjic, Sungbo Shim, Rachel A. Dalley, Sheila Shapouri, Kimberly A. Smith, Susan M. Sunkin, Amy Bernard, Jeffrey L. Bennett, Chang-Kyu Lee, Michael J. Hawrylycz, Allan R. Jones, David G. Amaral, Nenad Sestan, Fred H. Gage, Ed S. Lein
Development. 2013 Nov 15; 140(22): 4633–4644. doi: 10.1242/dev.097212
PMCID:
PMC3817946
AbstractArticle
12.
TULA-2, a novel histidine phosphatase, regulates bone remodeling by modulating osteoclast function
Steven H. Back, Naga Suresh Adapala, Mary F. Barbe, Nick C. Carpino, Alexander Y. Tsygankov, Archana Sanjay
Cell Mol Life Sci. 2013 Apr; 70(7): 1269–1284. Published online 2012 Nov 13. doi: 10.1007/s00018-012-1203-2
PMCID:
PMC3752794
AbstractArticlePDF–1.0M
13.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
14.
Once Phosphorylated, Tyrosines in Carboxyl Terminus of Protein-tyrosine Kinase Syk Interact with Signaling Proteins, Including TULA-2, a Negative Regulator of Mast Cell Degranulation
Rodrigo Orlandini de Castro, Juan Zhang, Jacqueline R. Groves, Emilia Alina Barbu, Reuben P. Siraganian
J Biol Chem. 2012 Mar 9; 287(11): 8194–8204. Published online 2012 Jan 20. doi: 10.1074/jbc.M111.326850
PMCID:
PMC3318758
AbstractArticlePDF–2.9M
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
Sts-2 Is a Phosphatase That Negatively Regulates Zeta-associated Protein (ZAP)-70 and T Cell Receptor Signaling Pathways
Boris San Luis, Ben Sondgeroth, Nicolas Nassar, Nick Carpino
J Biol Chem. 2011 May 6; 286(18): 15943–15954. Published online 2011 Mar 10. doi: 10.1074/jbc.M110.177634
PMCID:
PMC3091203
AbstractArticlePDF–1.6M
17.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
18.
A novel histidine tyrosine phosphatase, TULA-2, associates with Syk and negatively regulates GPVI signaling in platelets
Dafydd H. Thomas, Todd M. Getz, Tiffanny N. Newman, Carol A. Dangelmaier, Nick Carpino, Satya P. Kunapuli, Alexander Y. Tsygankov, James L. Daniel
Blood. 2010 Oct 7; 116(14): 2570–2578. Prepublished online 2010 Jun 29. doi: 10.1182/blood-2010-02-268136
PMCID:
PMC2953889
AbstractArticle
19.
Determination of the Substrate Specificity of Protein-tyrosine Phosphatase TULA-2 and Identification of Syk as a TULA-2 Substrate
Xianwen Chen, Lige Ren, Soochong Kim, Nicholas Carpino, James L. Daniel, Satya P. Kunapuli, Alexander Y. Tsygankov, Dehua Pei
J Biol Chem. 2010 Oct 8; 285(41): 31268–31276. Published online 2010 Jul 29. doi: 10.1074/jbc.M110.114181
PMCID:
PMC2951201
AbstractArticlePDF–1.0M
20.
The Sts proteins target tyrosine phosphorylated, ubiquitinated proteins within TCR signaling pathways
Nick Carpino, Yunting Chen, Nicolas Nassar, Hye-Won Oh
Mol Immunol. Author manuscript; available in PMC 2010 Oct 1.
Published in final edited form as: Mol Immunol. 2009 Oct; 46(16): 3224–3231. Published online 2009 Sep 5. doi: 10.1016/j.molimm.2009.08.015
PMCID:
PMC2757469
AbstractArticlePDF–684K

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