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Items: 1 to 20 of 23

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Elucidating the role of nicotinamide N-methyltransferase-p53 axis in the progression of chronic kidney disease
Xin Zhen, Yuxiang Sun, Hongchun Lin, Yuebo Huang, Tianwei Liu, Yuanqing Li, Hui Peng
PeerJ. 2023; 11: e16301. Published online 2023 Nov 8. doi: 10.7717/peerj.16301
PMCID:
PMC10638915
AbstractArticlePDF–22M
3.
Effect of nicotinamide N-methyltransferase on lipid accumulation in 3T3-L1 adipocytes
Wanfeng Xu, Ling Hou, Ping Li, Ling Li
Bioengineered. 2022; 13(5): 12421–12434. Published online 2022 May 21. doi: 10.1080/21655979.2022.2074768
PMCID:
PMC9276046
AbstractArticlePDF–4.6M
4.
Remote solid cancers rewire hepatic nitrogen metabolism via host nicotinamide-N-methyltransferase
Rin Mizuno, Hiroaki Hojo, Masatomo Takahashi, Soshiro Kashio, Sora Enya, Motonao Nakao, Riyo Konishi, Mayuko Yoda, Ayano Harata, Junzo Hamanishi, Hiroshi Kawamoto, Masaki Mandai, Yutaka Suzuki, Masayuki Miura, Takeshi Bamba, Yoshihiro Izumi, Shinpei Kawaoka
Nat Commun. 2022; 13: 3346. Published online 2022 Jun 15. doi: 10.1038/s41467-022-30926-z
PMCID:
PMC9200709
AbstractArticlePDF–1.1M
5.
The significance of NAD + metabolites and nicotinamide N-methyltransferase in chronic kidney disease
Rina Takahashi, Takeshi Kanda, Motoaki Komatsu, Tomoaki Itoh, Hitoshi Minakuchi, Hidenori Urai, Tomohiro Kuroita, Shuhei Shigaki, Tasuku Tsukamoto, Naoko Higuchi, Minoru Ikeda, Risa Yamanaka, Norito Yoshimura, Takashi Ono, Hideo Yukioka, Kazuhiro Hasegawa, Hirobumi Tokuyama, Shu Wakino, Hiroshi Itoh
Sci Rep. 2022; 12: 6398. Published online 2022 Apr 16. doi: 10.1038/s41598-022-10476-6
PMCID:
PMC9013399
AbstractArticlePDF–2.7M
6.
ER stress-induced upregulation of NNMT contributes to alcohol-related fatty liver development
Qing Song, Yingli Chen, Jun Wang, Liuyi Hao, Chuyi Huang, Alexandra Griffiths, Zhaoli Sun, Zhangxiang Zhou, Zhenyuan Song
J Hepatol. Author manuscript; available in PMC 2021 Oct 1.
Published in final edited form as: J Hepatol. 2020 Oct; 73(4): 783–793. Published online 2020 May 7. doi: 10.1016/j.jhep.2020.04.038
PMCID:
PMC8301603
AbstractArticlePDF–2.0M
7.
HOXA5 Participates in Brown Adipose Tissue and Epaxial Skeletal Muscle Patterning and in Brown Adipocyte Differentiation
Miriam A. Holzman, Abigail Ryckman, Tova M. Finkelstein, Kim Landry-Truchon, Kyra A. Schindler, Jenna M. Bergmann, Lucie Jeannotte, Jennifer H. Mansfield
Front Cell Dev Biol. 2021; 9: 632303. Published online 2021 Feb 25. doi: 10.3389/fcell.2021.632303
PMCID:
PMC7959767
AbstractArticlePDF–12M
8.
Subtype-Specific Genes that Characterize Subpopulations of Callosal Projection Neurons in Mouse Identify Molecularly Homologous Populations in Macaque Cortex
Ryann M. Fame, Colette Dehay, Henry Kennedy, Jeffrey D. Macklis
Cereb Cortex. 2017 Mar; 27(3): 1817–1830. Published online 2016 Feb 13. doi: 10.1093/cercor/bhw023
PMCID:
PMC6317451
AbstractArticlePDF–23M
9.
NNMT activation can contribute to the development of fatty liver disease by modulating the NAD+ metabolism
Motoaki Komatsu, Takeshi Kanda, Hidenori Urai, Arata Kurokochi, Rina Kitahama, Shuhei Shigaki, Takashi Ono, Hideo Yukioka, Kazuhiro Hasegawa, Hirobumi Tokuyama, Hiroshi Kawabe, Shu Wakino, Hiroshi Itoh
Sci Rep. 2018; 8: 8637. Published online 2018 Jun 5. doi: 10.1038/s41598-018-26882-8
PMCID:
PMC5988709
AbstractArticlePDF–2.3M
10.
Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization
Shangyu Hong, Jose M Moreno-Navarrete, Xiaojing Wei, Yusuke Kikukawa, Iphigenia Tzameli, Deepthi Prasad, Yoonjin Lee, John M Asara, Jose Manuel Fernandez-Real, Eleftheria Maratos-Flier, Pavlos Pissios
Nat Med. Author manuscript; available in PMC 2016 Feb 1.
Published in final edited form as: Nat Med. 2015 Aug; 21(8): 887–894. Published online 2015 Jul 13. doi: 10.1038/nm.3882
PMCID:
PMC4529375
AbstractArticlePDF–3.3M
11.
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity
Daniel Kraus, Qin Yang, Dong Kong, Alexander S. Banks, Lin Zhang, Joseph T. Rodgers, Eija Pirinen, Thomas C. Pulinilkunnil, Fengying Gong, Ya-chin Wang, Yana Cen, Anthony A. Sauve, John M. Asara, Odile D. Peroni, Brett P. Monia, Sanjay Bhanot, Leena Alhonen, Pere Puigserver, Barbara B. Kahn
Nature. Author manuscript; available in PMC 2015 Apr 10.
Published in final edited form as: Nature. 2014 Apr 10; 508(7495): 258–262. doi: 10.1038/nature13198
PMCID:
PMC4107212
AbstractArticlePDF–778K
12.
Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice
Matthew J. Harms, Jeff Ishibashi, Wenshan Wang, Hee-Woong Lim, Susumu Goyama, Tomohiko Sato, Mineo Kurokawa, Kyoung-Jae Won, Patrick Seale
Cell Metab. Author manuscript; available in PMC 2015 Apr 1.
Published in final edited form as: Cell Metab. 2014 Apr 1; 19(4): 593–604. doi: 10.1016/j.cmet.2014.03.007
PMCID:
PMC4012340
AbstractArticlePDF–2.3M
13.
EBF2 determines and maintains brown adipocyte identity
Sona Rajakumari, Jun Wu, Jeff Ishibashi, Lim Hee-Woong, An-Hoa Giang, Kyoung-Jae Won, Randall R. Reed, Patrick Seale
Cell Metab. Author manuscript; available in PMC 2014 Apr 2.
Published in final edited form as: Cell Metab. 2013 Apr 2; 17(4): 562–574. Published online 2013 Mar 14. doi: 10.1016/j.cmet.2013.01.015
PMCID:
PMC3622114
AbstractArticlePDF–3.2M
14.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
15.
Genome-Wide Location Analysis Reveals Distinct Transcriptional Circuitry by Paralogous Regulators Foxa1 and Foxa2
Irina M. Bochkis, Jonathan Schug, Diana Z. Ye, Svitlana Kurinna, Sabrina A. Stratton, Michelle C. Barton, Klaus H. Kaestner
PLoS Genet. 2012 Jun; 8(6): e1002770. Published online 2012 Jun 21. doi: 10.1371/journal.pgen.1002770
PMCID:
PMC3380847
AbstractArticlePDF–1.0M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
18.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
19.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K
20.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M

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