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Items: 1 to 20 of 47

1.
Tumor microenvironment restricts IL-10 induced multipotent progenitors to myeloid-lymphatic phenotype
Lisa Volk-Draper, Shaswati Athaiya, Maria Espinosa Gonzalez, Nihit Bhattarai, Andrew Wilber, Sophia Ran
PLoS One. 2024; 19(4): e0298465. Published online 2024 Apr 19. doi: 10.1371/journal.pone.0298465
PMCID:
PMC11029653
AbstractArticlePDF–4.6M
2.
IL-10 constrains sphingolipid metabolism to limit inflammation
Autumn G. York, Mathias H. Skadow, Joonseok Oh, Rihao Qu, Quan D. Zhou, Wei-Yuan Hsieh, Walter K. Mowel, J. Richard Brewer, Eleanna Kaffe, Kevin J. Williams, Yuval Kluger, Stephen T. Smale, Jason M. Crawford, Steven J. Bensinger, Richard A. Flavell
Nature. 2024; 627(8004): 628–635. Published online 2024 Feb 21. doi: 10.1038/s41586-024-07098-5
PMCID:
PMC10954550
AbstractArticlePDF–4.3M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
Regulatory T cells suppress CD4+ effector T cell activation by controlling protein synthesis
Lomon So, Kazushige Obata-Ninomiya, Alex Hu, Virginia S. Muir, Ayako Takamori, Jing Song, Jane H. Buckner, Ram Savan, Steven F. Ziegler
J Exp Med. 2023 Mar 6; 220(3): e20221676. Published online 2023 Jan 4. doi: 10.1084/jem.20221676
PMCID:
PMC9827529
AbstractArticlePDF–5.2M
5.
Antigen presentation safeguards the integrity of the hematopoietic stem cell pool
Pablo Hernández-Malmierca, Dominik Vonficht, Alexandra Schnell, Hannah J. Uckelmann, Alina Bollhagen, Mohamed A.A. Mahmoud, Sophie-Luise Landua, Elise van der Salm, Christine L. Trautmann, Simon Raffel, Florian Grünschläger, Raphael Lutz, Michael Ghosh, Simon Renders, Nádia Correia, Elisa Donato, Karin O. Dixon, Christoph Hirche, Carolin Andresen, Claudia Robens, Paula S. Werner, Tobias Boch, David Eisel, Wolfram Osen, Franziska Pilz, Adriana Przybylla, Corinna Klein, Frank Buchholz, Michael D. Milsom, Marieke A.G. Essers, Stefan B. Eichmüller, Wolf-Karsten Hofmann, Daniel Nowak, Daniel Hübschmann, Michael Hundemer, Christian Thiede, Lars Bullinger, Carsten Müller-Tidow, Scott A. Armstrong, Andreas Trumpp, Vijay K. Kuchroo, Simon Haas
Cell Stem Cell. Author manuscript; available in PMC 2023 May 5.
Published in final edited form as: Cell Stem Cell. 2022 May 5; 29(5): 760–775.e10. doi: 10.1016/j.stem.2022.04.007
PMCID:
PMC9202612
AbstractArticlePDF–2.2M
6.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
7.
STAT3 Inhibits CD103+ cDC1 Vaccine Efficacy in Murine Breast Cancer
Taylor T. Chrisikos, Yifan Zhou, Haiyan S. Li, Rachel L. Babcock, Xianxiu Wan, Bhakti Patel, Kathryn Newton, James J. Mancuso, Stephanie S. Watowich
Cancers (Basel) 2020 Jan; 12(1): 128. Published online 2020 Jan 4. doi: 10.3390/cancers12010128
PMCID:
PMC7017236
AbstractArticlePDF–2.8M
8.
Interleukin 22 disrupts pancreatic function in newborn mice expressing IL-23
Lili Chen, Valentina Strohmeier, Zhengxiang He, Madhura Deshpande, Jovani Catalan-Dibene, Scott K. Durum, Thomas M. Moran, Thomas Kraus, Huabao Xiong, Jeremiah J. Faith, Chhinder P. Sodhi, David J. Hackam, Sergio A. Lira, Glaucia C. Furtado
Nat Commun. 2019; 10: 4517. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12540-8
PMCID:
PMC6778080
AbstractArticlePDF–7.6M
9.
IFN-mediated negative feedback supports bacteria class-specific macrophage inflammatory responses
Rachel A Gottschalk, Michael G Dorrington, Bhaskar Dutta, Kathleen S Krauss, Andrew J Martins, Stefan Uderhardt, Waipan Chan, John S Tsang, Parizad Torabi-Parizi, Iain DC Fraser, Ronald N Germain
eLife. 2019; 8: e46836. Published online 2019 Aug 6. doi: 10.7554/eLife.46836
PMCID:
PMC6684266
AbstractArticlePDF–1.0M
10.
Chronic lymphocytic leukemia derived interleukin-10 suppresses anti-tumor immunity
Sara S. Alhakeem, Mary K. McKenna, Karine Z. Oben, Sunil K. Noothi, Jacqueline R. Rivas, Gerhard C. Hildebrandt, Roger A. Fleischman, Vivek M. Rangnekar, Natarajan Muthusamy, Subbarao Bondada
J Immunol. Author manuscript; available in PMC 2019 Jun 15.
Published in final edited form as: J Immunol. 2018 Jun 15; 200(12): 4180–4189. Published online 2018 Apr 30. doi: 10.4049/jimmunol.1800241
PMCID:
PMC6555426
AbstractArticlePDF–4.0M
11.
Blocking IL-10 receptor signaling ameliorates Mycobacterium tuberculosis infection during influenza-induced exacerbation
Sarah Ring, Lars Eggers, Jochen Behrends, Adam Wutkowski, Dominik Schwudke, Andrea Kröger, Alexandra Maximiliane Hierweger, Christoph Hölscher, Gülsah Gabriel, Bianca E. Schneider
JCI Insight. 2019 May 16; 4(10): e126533. Published online 2019 May 16. doi: 10.1172/jci.insight.126533
PMCID:
PMC6542649
AbstractArticlePDF–3.6M
12.
Adaptive plasticity of IL-10+ and IL-35+ Treg cells cooperatively promotes tumor T cell exhaustion
Deepali V. Sawant, Hiroshi Yano, Maria Chikina, Qianxia Zhang, Mengting Liao, Chang Liu, Derrick J Callahan, Zhe Sun, Tao Sun, Tracy Tabib, Arjun Pennathur, David B. Corry, James D. Luketich, Robert Lafyatis, Wei Chen, Amanda C. Poholek, Tullia C. Bruno, Creg J. Workman, Dario A.A. Vignali
Nat Immunol. Author manuscript; available in PMC 2019 Oct 1.
Published in final edited form as: Nat Immunol. 2019 Jun; 20(6): 724–735. Published online 2019 Apr 1. doi: 10.1038/s41590-019-0346-9
PMCID:
PMC6531353
AbstractArticlePDF–3.6M
13.
Female-biased embryonic death from genomic instability-induced inflammation
Adrian J. McNairn, Chen-Hua Chuang, Jordana C. Bloom, Marsha D. Wallace, John C. Schimenti
Nature. Author manuscript; available in PMC 2019 Aug 20.
Published in final edited form as: Nature. 2019 Mar; 567(7746): 105–108. Published online 2019 Feb 20. doi: 10.1038/s41586-019-0936-6
PMCID:
PMC6497049
AbstractArticlePDF–1018K
14.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
15.
STAT1 signaling shields T cells from NK cell-mediated cytotoxicity
Yu Hui Kang, Amlan Biswas, Michael Field, Scott B. Snapper
Nat Commun. 2019; 10: 912. Published online 2019 Feb 22. doi: 10.1038/s41467-019-08743-8
PMCID:
PMC6385318
AbstractArticlePDF–1.8M
16.
Regulatory T cells promote macrophage efferocytosis during inflammation resolution
Jonathan D. Proto, Amanda C. Doran, Galina Gusarova, Arif Yurdagul, Jr., Erdi Sozen, Manikandan Subramanian, Mohammad N. Islam, Christina C. Rymond, Jasper Du, Jaime Hook, George Kuriakose, Jahar Bhattacharya, Ira Tabas
Immunity. Author manuscript; available in PMC 2019 Oct 16.
Published in final edited form as: Immunity. 2018 Sep 25 : S1074-7613(18)30335-2. Published online 2018 Sep 25. doi: 10.1016/j.immuni.2018.07.015
PMCID:
PMC6192849
ArticlePDF–967K
17.
Interleukin-15 Complex Treatment Protects Mice from Cerebral Malaria by Inducing Interleukin-10-Producing Natural Killer Cells
Kristina S. Burrack, Matthew A. Huggins, Emily Taras, Philip Dougherty, Christine M. Henzler, Rendong Yang, Sarah Alter, Emily K. Jeng, Hing C. Wong, Martin Felices, Frank Cichocki, Jeffrey S. Miller, Geoffrey T. Hart, Aaron J. Johnson, Stephen C. Jameson, Sara E. Hamilton
Immunity. Author manuscript; available in PMC 2019 Apr 17.
Published in final edited form as: Immunity. 2018 Apr 17; 48(4): 760–772.e4. Published online 2018 Apr 3. doi: 10.1016/j.immuni.2018.03.012
PMCID:
PMC5906161
AbstractArticlePDF–1.4M
18.
Re-evaluation of IL-10 signaling reveals novel insights on the contribution of the intracellular domain of the IL-10R2 chain
Ruud H. P. Wilbers, Debbie R. van Raaij, Lotte B. Westerhof, Jaap Bakker, Geert Smant, Arjen Schots
PLoS One. 2017; 12(10): e0186317. Published online 2017 Oct 10. doi: 10.1371/journal.pone.0186317
PMCID:
PMC5634637
AbstractArticlePDF–5.5M
19.
Macrophage dysfunction initiates colitis during weaning of infant mice lacking the interleukin-10 receptor
Naresh S Redhu, Vasudevan Bakthavatchalu, Evan A Conaway, Dror S Shouval, Amy Tsou, Jeremy A Goettel, Amlan Biswas, Chuanwu Wang, Michael Field, Werner Muller, Andre Bleich, Ning Li, Georg K Gerber, Lynn Bry, James G Fox, Scott B Snapper, Bruce H Horwitz
eLife. 2017; 6: e27652. Published online 2017 Jul 5. doi: 10.7554/eLife.27652
PMCID:
PMC5531923
AbstractArticlePDF–6.4M
20.
Insensitivity of Astrocytes to Interleukin-10 Signaling following Peripheral Immune Challenge Results in Prolonged Microglial Activation in the Aged Brain
Diana M. Norden, Paige J. Trojanowski, Frederick R. Walker, Jonathan P. Godbout
Neurobiol Aging. Author manuscript; available in PMC 2017 Aug 1.
Published in final edited form as: Neurobiol Aging. 2016 Aug; 44: 22–41. Published online 2016 Apr 27. doi: 10.1016/j.neurobiolaging.2016.04.014
PMCID:
PMC5467746
AbstractArticlePDF–2.0M

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