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Select item 115479091.

Interindividual Variation in Gut Nitrergic Neuron Density Is Regulated By GDNF Levels and ETV1

Heikki T. Virtanen, Peyman Choopanian, L. Lauriina Porokuokka, Richard Forsgård, Daniel R. Garton, Soophie Olfat, Riitta Korpela, Mehdi Mirzaie, Jaan-Olle Andressoo

Cell Mol Gastroenterol Hepatol. 2024; 18(6): 101405. Published online 2024 Sep 17. doi: 10.1016/j.jcmgh.2024.101405

PMCID:: PMC11547909

Abstract Article PDF–8.1M

Select item 115209482.

Pcgf1 gene disruption reveals primary involvement of epigenetic mechanism in neuronal subtype specification in the enteric nervous system

Bayu Pratama Putra, Keisuke Ito, Carla Cirillo, Mukhamad Sunardi, Haruhiko Koseki, Toshihiro Uesaka, Hideki Enomoto

Dev Growth Differ. 2023 Oct; 65(8): 461–469. Published online 2023 Aug 18. doi: 10.1111/dgd.12880

PMCID:: PMC11520948

Abstract Article PDF–3.7M

Select item 112428643.

Skeletal Muscle UCHL1 Negatively Regulates Muscle Development and Recovery after Muscle Injury

Ryan Antony, Katherine Aby, Morgan Montgomery, Yifan Li

Int J Mol Sci. 2024 Jul; 25(13): 7330. Published online 2024 Jul 4. doi: 10.3390/ijms25137330

PMCID:: PMC11242864

Abstract Article PDF–5.6M

Select item 109735254.

A novel proteomic signature of osteoclast differentiation unveils the deubiquitinase UCHL1 as a necessary osteoclastogenic driver

Maria Materozzi, Massimo Resnati, Cecilia Facchi, Matteo Trudu, Ugo Orfanelli, Tommaso Perini, Luigi Gennari, Enrico Milan, Simone Cenci

Sci Rep. 2024; 14: 7290. Published online 2024 Mar 27. doi: 10.1038/s41598-024-57898-y

PMCID:: PMC10973525

Abstract Article PDF–8.3M

Select item 109377945.

Deubiquitinase UCHL1 promotes angiogenesis and blood–spinal cord barrier function recovery after spinal cord injury by stabilizing Sox17

Jiaxing Wang, Chengyue Ji, Wu Ye, Yuluo Rong, Xuhui Ge, Zhuanghui Wang, Pengyu Tang, Zheng Zhou, Yongjun Luo, Weihua Cai

Cell Mol Life Sci. 2024 Dec; 81(1): 137. Published online 2024 Mar 13. doi: 10.1007/s00018-024-05186-3

PMCID:: PMC10937794

Abstract Article PDF–5.3M

Select item 109176606.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107845247.

Diabetic sensory neuropathy and insulin resistance are induced by loss of UCHL1 in Drosophila

Daewon Lee, Eunju Yoon, Su Jin Ham, Kunwoo Lee, Hansaem Jang, Daihn Woo, Da Hyun Lee, Sehyeon Kim, Sekyu Choi, Jongkyeong Chung

Nat Commun. 2024; 15: 468. Published online 2024 Jan 11. doi: 10.1038/s41467-024-44747-9

PMCID:: PMC10784524

Abstract Article PDF–4.8M

Select item 106916568.

A developmental atlas of somatosensory diversification and maturation in the dorsal root ganglia by single-cell mass cytometry

Austin B. Keeler, Amy L. Van Deusen, Irene C. Gadani, Corey M. Williams, Sarah M Goggin, Ashley K. Hirt, Shayla A. Vradenburgh, Kristen I. Fread, Emily A. Puleo, Lucy Jin, O. Yipkin Calhan, Christopher D. Deppmann, Eli R. Zunder

Nat Neurosci. Author manuscript; available in PMC 2023 Dec 1.

Published in final edited form as: Nat Neurosci. 2022 Nov; 25(11): 1543–1558. Published online 2022 Oct 27. doi: 10.1038/s41593-022-01181-8

PMCID:: PMC10691656

Abstract Article PDF–8.2M

Select item 105721879.

UCHL1 Regulates Radiation Lung Injury via Sphingosine Kinase-1

Yulia Epshtein, Biji Mathew, Weiguo Chen, Jeffrey R. Jacobson

Cells. 2023 Oct; 12(19): 2405. Published online 2023 Oct 5. doi: 10.3390/cells12192405

PMCID:: PMC10572187

Abstract Article PDF–2.4M

Select item 1030785210.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 1026634811.

Osteopontin depletion in macrophages perturbs proteostasis via regulating UCHL1-UPS axis and mitochondria-mediated apoptosis

Altan Rentsendorj, Koen Raedschelders, Dieu-Trang Fuchs, Julia Sheyn, Vineet Vaibhav, Rebecca A. Porritt, Haoshen Shi, Jargalsaikhan Dagvadorj, Juliana de Freitas Germano, Yosef Koronyo, Moshe Arditi, Keith L. Black, Bhakta Prasad Gaire, Jennifer E. Van Eyk, Maya Koronyo-Hamaoui

Front Immunol. 2023; 14: 1155935. Published online 2023 May 30. doi: 10.3389/fimmu.2023.1155935

PMCID:: PMC10266348

Abstract Article PDF–12M

Select item 1019788912.

The deubiquitinase UCHL1 negatively controls osteoclastogenesis by regulating TAZ/NFATC1 signalling

Zhenhua Feng, Siyue Tao, Zhaobo Huang, Bingjie Zheng, Xiangxi Kong, Yufeng Xiang, Qibin Zhang, Haixin Song, Zhikun Xu, Xiaoan Wei, Fengdong Zhao, Jian Chen

Int J Biol Sci. 2023; 19(8): 2319–2332. Published online 2023 Apr 24. doi: 10.7150/ijbs.82152

PMCID:: PMC10197889

Abstract Article PDF–7.7M

Select item 1010202213.

Non-functional ubiquitin C-terminal hydrolase L1 drives podocyte injury through impairing proteasomes in autoimmune glomerulonephritis

Julia Reichelt, Wiebke Sachs, Sarah Frömbling, Julia Fehlert, Maja Studencka-Turski, Anna Betz, Desiree Loreth, Lukas Blume, Susanne Witt, Sandra Pohl, Johannes Brand, Maire Czesla, Jan Knop, Bogdan I. Florea, Stephanie Zielinski, Marlies Sachs, Elion Hoxha, Irm Hermans-Borgmeyer, Gunther Zahner, Thorsten Wiech, Elke Krüger, Catherine Meyer-Schwesinger

Nat Commun. 2023; 14: 2114. Published online 2023 Apr 13. doi: 10.1038/s41467-023-37836-8

Correction in:: Nat Commun. 2023; 14: 2453.

PMCID:: PMC10102022

Abstract Article PDF–9.7M

Select item 999226714.

Role of UCHL1 in the pathogenesis of neurodegenerative diseases and brain injury

Zhiping Mi, Steven H Graham

Ageing Res Rev. Author manuscript; available in PMC 2024 Apr 1.

Published in final edited form as: Ageing Res Rev. 2023 Apr; 86: 101856. Published online 2023 Jan 19. doi: 10.1016/j.arr.2023.101856

PMCID:: PMC9992267

Abstract Article PDF–629K

Select item 972465715.

The AAA‐ATPase ATAD1 and its partners promote degradation of desmin intermediate filaments in muscle

Dina Aweida, Shenhav Cohen

EMBO Rep. 2022 Dec; 23(12): e55175. Published online 2022 Oct 24. doi: 10.15252/embr.202255175

PMCID:: PMC9724657

Abstract Article PDF–3.0M

Select item 960569216.

Little skate genome provides insights into genetic programs essential for limb-based locomotion

DongAhn Yoo, Junhee Park, Chul Lee, Injun Song, Young Ho Lee, Tery Yun, Hyemin Lee, Adriana Heguy, Jae Yong Han, Jeremy S Dasen, Heebal Kim, Myungin Baek

eLife. 2022; 11: e78345. Published online 2022 Oct 26. doi: 10.7554/eLife.78345

PMCID:: PMC9605692

Abstract Article PDF–8.4M

Select item 960386017.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 956689918.

In vivo visualization and molecular targeting of the cardiac conduction system

William R. Goodyer, Benjamin M. Beyersdorf, Lauren Duan, Nynke S. van den Berg, Sruthi Mantri, Francisco X. Galdos, Nazan Puluca, Jan W. Buikema, Soah Lee, Darren Salmi, Elise R. Robinson, Stephan Rogalla, Dillon P. Cogan, Chaitan Khosla, Eben L. Rosenthal, Sean M. Wu

J Clin Invest. 2022 Oct 17; 132(20): e156955. Published online 2022 Oct 17. doi: 10.1172/JCI156955

PMCID:: PMC9566899

Abstract Article PDF–9.4M

Select item 954903019.

Structural basis for specific inhibition of the deubiquitinase UCHL1

Christian Grethe, Mirko Schmidt, Gian-Marvin Kipka, Rachel O’Dea, Kai Gallant, Petra Janning, Malte Gersch

Nat Commun. 2022; 13: 5950. Published online 2022 Oct 10. doi: 10.1038/s41467-022-33559-4

PMCID:: PMC9549030

Abstract Article PDF–4.9M

Select item 948193320.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

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