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Select item 103001651.

Dispensable role of Rac1 and Rac3 after cochlear hair cell specification

Takashi Nakamura, Hirofumi Sakaguchi, Hiroaki Mohri, Yuzuru Ninoyu, Akihiro Goto, Taro Yamaguchi, Yoshitaka Hishikawa, Michiyuki Matsuda, Naoaki Saito, Takehiko Ueyama

J Mol Med (Berl) 2023; 101(7): 843–854. Published online 2023 May 19. doi: 10.1007/s00109-023-02317-4

PMCID:: PMC10300165

Abstract Article PDF–2.1M

Select item 102089582.

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome

Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh

Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5

PMCID:: PMC10208958

Abstract Article PDF–7.0M

Select item 99577273.

RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells

Fuhui Chen, Sevim B. Gurler, David Novo, Cigdem Selli, Denis G. Alferez, Secil Eroglu, Kyriaki Pavlou, Jingwei Zhang, Andrew H. Sims, Neil E. Humphreys, Antony Adamson, Andrew Campbell, Owen J. Sansom, Cathy Tournier, Robert B. Clarke, Keith Brennan, Charles H. Streuli, Ahmet Ucar

Oncogene. 2023; 42(9): 679–692. Published online 2023 Jan 5. doi: 10.1038/s41388-022-02574-6

PMCID:: PMC9957727

Abstract Article PDF–2.9M

Select item 99382164.

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes

Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x

PMCID:: PMC9938216

Abstract Article PDF–5.3M

Select item 94369605.

Rac-deficient cerebellar granule neurons die before they migrate to the internal granule layer

Kei-ichi Katayama, Yi Zheng, Norimitsu Inoue

Sci Rep. 2022; 12: 14848. Published online 2022 Sep 1. doi: 10.1038/s41598-022-19252-y

PMCID:: PMC9436960

Abstract Article PDF–8.7M

Select item 84646036.

Negative regulation of TGFβ-induced apoptosis by RAC1B enhances intestinal tumourigenesis

Victoria Gudiño, Patrizia Cammareri, Caroline V. Billard, Kevin B. Myant

Cell Death Dis. 2021 Oct; 12(10): 873. Published online 2021 Sep 25. doi: 10.1038/s41419-021-04177-7

PMCID:: PMC8464603

Abstract Article PDF–8.7M

Select item 83132397.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 80580718.

RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways

Victoria Gudiño, Sebastian Öther-Gee Pohl, Caroline V. Billard, Patrizia Cammareri, Alfonso Bolado, Stuart Aitken, David Stevenson, Adam E. Hall, Mark Agostino, John Cassidy, Colin Nixon, Alex von Kriegsheim, Paz Freile, Linda Popplewell, George Dickson, Laura Murphy, Ann Wheeler, Malcolm Dunlop, Farhat Din, Douglas Strathdee, Owen J. Sansom, Kevin B. Myant

Nat Commun. 2021; 12: 2335. Published online 2021 Apr 20. doi: 10.1038/s41467-021-22531-3

PMCID:: PMC8058071

Abstract Article PDF–12M

Select item 66750909.

Rac1 and Rac3 GTPases differently influence the morphological maturation of dendritic spines in hippocampal neurons

Roberta Pennucci, Irene Gucciardi, Ivan de Curtis

PLoS One. 2019; 14(8): e0220496. Published online 2019 Aug 1. doi: 10.1371/journal.pone.0220496

PMCID:: PMC6675090

Abstract Article PDF–2.3M

Select item 667241210.

Rac1 Controls the Formation of Midline Commissures and the Competency of Tangential Migration in Ventral Telencephalic Neurons

Lei Chen, Guanghong Liao, Ronald R. Waclaw, Kevin A. Burns, Diana Linquist, Kenneth Campbell, Yi Zheng, Chia-Yi Kuan

J Neurosci. 2007 Apr 4; 27(14): 3884–3893. doi: 10.1523/JNEUROSCI.3509-06.2007

PMCID:: PMC6672412

Abstract Article PDF–750K

Select item 660230911.

Developmental origins for semilunar valve stenosis identified in mice harboring congenital heart disease-associated GATA4 mutation

Stephanie LaHaye, Uddalak Majumdar, Jun Yasuhara, Sara N. Koenig, Adrianna Matos-Nieves, Rahul Kumar, Vidu Garg

Dis Model Mech. 2019 Jun 1; 12(6): dmm036764. Published online 2019 Jun 24. doi: 10.1242/dmm.036764

PMCID:: PMC6602309

Abstract Article

Select item 571628412.

Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation

Sara K. Donnelly, Ramon Cabrera, Serena P.H. Mao, John R. Christin, Bin Wu, Wenjun Guo, Jose Javier Bravo-Cordero, John S. Condeelis, Jeffrey E. Segall, Louis Hodgson

J Cell Biol. 2017 Dec 4; 216(12): 4331–4349. doi: 10.1083/jcb.201704048

PMCID:: PMC5716284

Abstract Article PDF–2.7M

Select item 517413113.

Identification of a Protein Network Driving Neuritogenesis of MGE-Derived GABAergic Interneurons

Sira A. Franchi, Veronica Astro, Romina Macco, Diletta Tonoli, Jean-Vianney Barnier, Martina Botta, Ivan de Curtis

Front Cell Neurosci. 2016; 10: 289. Published online 2016 Dec 21. doi: 10.3389/fncel.2016.00289

PMCID:: PMC5174131

Abstract Article PDF–4.0M

Select item 471280914.

Loss of Either Rac1 or Rac3 GTPase Differentially Affects the Behavior of Mutant Mice and the Development of Functional GABAergic Networks

Roberta Pennucci, Francesca Talpo, Veronica Astro, Valentina Montinaro, Lorenzo Morè, Marco Cursi, Valerio Castoldi, Sara Chiaretti, Veronica Bianchi, Silvia Marenna, Marco Cambiaghi, Diletta Tonoli, Letizia Leocani, Gerardo Biella, Patrizia D'Adamo, Ivan de Curtis

Cereb Cortex. 2016 Feb; 26(2): 873–890. Published online 2015 Nov 17. doi: 10.1093/cercor/bhv274

PMCID:: PMC4712809

Abstract Article PDF–1.6M

Select item 455775315.

Beads-free protein immunoprecipitation for a mass spectrometry-based interactome and posttranslational modifications analysis

Michal Mikula, Tymon Rubel, Jakub Karczmarski, Malgorzata Statkiewicz, Karol Bomsztyk, Jerzy Ostrowski

Proteome Sci. 2015; 13: 23. Published online 2015 Sep 2. doi: 10.1186/s12953-015-0079-0

PMCID:: PMC4557753

Abstract Article PDF–1.5M

Select item 453741716.

Rac-GTPases Regulate Microtubule Stability and Axon Growth of Cortical GABAergic Interneurons

Simona Tivodar, Katerina Kalemaki, Zouzana Kounoupa, Marina Vidaki, Kostas Theodorakis, Myrto Denaxa, Nicoletta Kessaris, Ivan de Curtis, Vassilis Pachnis, Domna Karagogeos

Cereb Cortex. 2015 Sep; 25(9): 2370–2382. Published online 2014 Mar 13. doi: 10.1093/cercor/bhu037

PMCID:: PMC4537417

Abstract Article PDF–1.1M

Select item 443200417.

Perivascular deletion of murine Rac reverses the ratio of marrow arterioles and sinusoid vessels and alters hematopoiesis in vivo

Marioara F. Ciuculescu, Shin-Young Park, Kimberly Canty, Ronald Mathieu, Leslie E. Silberstein, David A. Williams

Blood. 2015 May 14; 125(20): 3105–3113. Prepublished online 2015 Mar 30. doi: 10.1182/blood-2014-10-604892

PMCID:: PMC4432004

Abstract Article

Select item 431955918.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 397761919.

Rac1 and Rac3 GTPases Control Synergistically the Development of Cortical and Hippocampal GABAergic Interneurons

Valentina Vaghi, Roberta Pennucci, Francesca Talpo, Sara Corbetta, Valentina Montinaro, Cinzia Barone, Laura Croci, Paolo Spaiardi, G. Giacomo Consalez, Gerardo Biella, Ivan de Curtis

Cereb Cortex. 2014 May; 24(5): 1247–1258. Published online 2012 Dec 20. doi: 10.1093/cercor/bhs402

PMCID:: PMC3977619

Abstract Article PDF–22M

Select item 373350320.

Matrix Metalloproteinase Induction of Rac1b, a Key Effector of Lung Cancer Progression

Melody L. Stallings-Mann, Jens Waldmann, Ying Zhang, Erin Miller, Mona L. Gauthier, Daniel W. Visscher, Gregory P. Downey, Evette S. Radisky, Alan P. Fields, Derek C. Radisky

Sci Transl Med. Author manuscript; available in PMC 2013 Aug 5.

Published in final edited form as: Sci Transl Med. 2012 Jul 11; 4(142): 142ra95. doi: 10.1126/scitranslmed.3004062

PMCID:: PMC3733503

Abstract Article PDF–5.9M

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