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Items: 1 to 20 of 29

1.
Non-motor symptoms associated with progressive loss of dopaminergic neurons in a mouse model of Parkinson’s disease
Anna Radlicka-Borysewska, Judyta Jabłońska, Michał Lenarczyk, Łukasz Szumiec, Zofia Harda, Monika Bagińska, Justyna Barut, Joanna Pera, Grzegorz Kreiner, Daniel K. Wójcik, Jan Rodriguez Parkitna
Front Neurosci. 2024; 18: 1375265. Published online 2024 Apr 30. doi: 10.3389/fnins.2024.1375265
PMCID:
PMC11091341
AbstractArticlePDF–4.7M
2.
Nucleolar stress controls mutant Huntington toxicity and monitors Huntington’s disease progression
Aynur Sönmez, Rasem Mustafa, Salome T. Ryll, Francesca Tuorto, Ludivine Wacheul, Donatella Ponti, Christian Litke, Tanja Hering, Kerstin Kojer, Jenniver Koch, Claudia Pitzer, Joachim Kirsch, Andreas Neueder, Grzegorz Kreiner, Denis L. J. Lafontaine, Michael Orth, Birgit Liss, Rosanna Parlato
Cell Death Dis. 2021 Dec; 12(12): 1139. Published online 2021 Dec 8. doi: 10.1038/s41419-021-04432-x
PMCID:
PMC8655027
AbstractArticlePDF–4.3M
3.
Activation of an Endogenous Suicide Response after Perturbation of rRNA Synthesis Leads to Neurodegeneration in Mice
Rosanna Parlato, Grzegorz Kreiner, Gitta Erdmann, Claus Rieker, Stefanie Stotz, Ella Savenkova, Stefan Berger, Ingrid Grummt, Günther Schütz
J Neurosci. 2008 Nov 26; 28(48): 12759–12764. doi: 10.1523/JNEUROSCI.2439-08.2008
PMCID:
PMC6671823
AbstractArticlePDF–478K
4.
Nucleolar Disruption in Dopaminergic Neurons Leads to Oxidative Damage and Parkinsonism through Repression of Mammalian Target of Rapamycin Signaling
Claus Rieker, David Engblom, Grzegorz Kreiner, Andrii Domanskyi, Andreas Schober, Stefanie Stotz, Manuela Neumann, Xuejun Yuan, Ingrid Grummt, Günther Schütz, Rosanna Parlato
J Neurosci. 2011 Jan 12; 31(2): 453–460. doi: 10.1523/JNEUROSCI.0590-10.2011
PMCID:
PMC6623444
AbstractArticlePDF–1.9M
5.
Integration of the Deacetylase SIRT1 in the Response to Nucleolar Stress: Metabolic Implications for Neurodegenerative Diseases
Grzegorz Kreiner, Aynur Sönmez, Birgit Liss, Rosanna Parlato
Front Mol Neurosci. 2019; 12: 106. Published online 2019 Apr 26. doi: 10.3389/fnmol.2019.00106
PMCID:
PMC6499230
AbstractArticlePDF–1.4M
6.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
7.
Stimulation of noradrenergic transmission by reboxetine is beneficial for a mouse model of progressive parkinsonism
Grzegorz Kreiner, Katarzyna Rafa-Zabłocka, Justyna Barut, Piotr Chmielarz, Marta Kot, Monika Bagińska, Rosanna Parlato, Władysława Anna Daniel, Irena Nalepa
Sci Rep. 2019; 9: 5262. Published online 2019 Mar 27. doi: 10.1038/s41598-019-41756-3
PMCID:
PMC6437187
AbstractArticlePDF–1.8M
8.
A unique enhancer boundary complex on the mouse ribosomal RNA genes persists after loss of Rrn3 or UBF and the inactivation of RNA polymerase I transcription
Chelsea Herdman, Jean-Clement Mars, Victor Y. Stefanovsky, Michel G. Tremblay, Marianne Sabourin-Felix, Helen Lindsay, Mark D. Robinson, Tom Moss
PLoS Genet. 2017 Jul; 13(7): e1006899. Published online 2017 Jul 17. doi: 10.1371/journal.pgen.1006899
PMCID:
PMC5536353
AbstractArticlePDF–6.0M
9.
Genetic mutations linked to Parkinson's disease differentially control nucleolar activity in pre-symptomatic mouse models
Valentin Evsyukov, Andrii Domanskyi, Holger Bierhoff, Suzana Gispert, Rasem Mustafa, Falk Schlaudraff, Birgit Liss, Rosanna Parlato
Dis Model Mech. 2017 May 1; 10(5): 633–643. doi: 10.1242/dmm.028092
PMCID:
PMC5451170
AbstractArticle
10.
Heat shock represses rRNA synthesis by inactivation of TIF-IA and lncRNA-dependent changes in nucleosome positioning
Zhongliang Zhao, Marcel A. Dammert, Sven Hoppe, Holger Bierhoff, Ingrid Grummt
Nucleic Acids Res. 2016 Sep 30; 44(17): 8144–8152. Published online 2016 Jun 1. doi: 10.1093/nar/gkw496
PMCID:
PMC5041454
AbstractArticlePDF–1.6M
11.
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt
Jernej Murn, Kathi Zarnack, Yawei J. Yang, Omer Durak, Elisabeth A. Murphy, Sihem Cheloufi, Dilenny M. Gonzalez, Marianna Teplova, Tomaž Curk, Johannes Zuber, Dinshaw J. Patel, Jernej Ule, Nicholas M. Luscombe, Li-Huei Tsai, Christopher A. Walsh, Yang Shi
Genes Dev. 2015 Mar 1; 29(5): 501–512. doi: 10.1101/gad.258483.115
PMCID:
PMC4358403
AbstractArticlePDF–1.4M
12.
Akt activation enhances ribosomal RNA synthesis through casein kinase II and TIF-IA
Le Xuan Truong Nguyen, Beverly S. Mitchell
Proc Natl Acad Sci U S A. 2013 Dec 17; 110(51): 20681–20686. Published online 2013 Dec 2. doi: 10.1073/pnas.1313097110
PMCID:
PMC3870716
AbstractArticlePDF–1.4M
13.
Impaired rRNA synthesis triggers homeostatic responses in hippocampal neurons
Anna Kiryk, Katharina Sowodniok, Grzegorz Kreiner, Jan Rodriguez-Parkitna, Aynur Sönmez, Tomasz Górkiewicz, Holger Bierhoff, Marcin Wawrzyniak, Artur K. Janusz, Birgit Liss, Witold Konopka, Günther Schütz, Leszek Kaczmarek, Rosanna Parlato
Front Cell Neurosci. 2013; 7: 207. Published online 2013 Nov 11. doi: 10.3389/fncel.2013.00207
PMCID:
PMC3823236
AbstractArticlePDF–1.5M
14.
A neuroprotective phase precedes striatal degeneration upon nucleolar stress
G Kreiner, H Bierhoff, M Armentano, J Rodriguez-Parkitna, K Sowodniok, J R Naranjo, L Bonfanti, B Liss, G Schütz, I Grummt, R Parlato
Cell Death Differ. 2013 Nov; 20(11): 1455–1464. Published online 2013 Jun 14. doi: 10.1038/cdd.2013.66
PMCID:
PMC3792439
AbstractArticlePDF–2.7M
15.
DNA Binding by the Ribosomal DNA Transcription Factor Rrn3 Is Essential for Ribosomal DNA Transcription
Ann Stepanchick, Huijun Zhi, Alice H. Cavanaugh, Katrina Rothblum, David A. Schneider, Lawrence I. Rothblum
J Biol Chem. 2013 Mar 29; 288(13): 9135–9144. Published online 2013 Feb 7. doi: 10.1074/jbc.M112.444265
PMCID:
PMC3610986
AbstractArticlePDF–1.3M
16.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
19.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
20.
Phosphorylation by Casein Kinase 2 Facilitates rRNA Gene Transcription by Promoting Dissociation of TIF-IA from Elongating RNA Polymerase I
Holger Bierhoff, Miroslav Dundr, Annemieke A. Michels, Ingrid Grummt
Mol Cell Biol. 2008 Aug; 28(16): 4988–4998. Published online 2008 Jun 16. doi: 10.1128/MCB.00492-08
PMCID:
PMC2519707
AbstractArticlePDF–1.1M

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