PMC Links for GEO Profiles (Select 61476506) - PMC

Federica Rubbino, Valentina Garlatti, Valeria Garzarelli, Luca Massimino, Salvatore Spanò, Paolo Iadarola, Maddalena Cagnone, Martin Giera, Marieke Heijink, Simone Guglielmetti, Vincenzo Arena, Alberto Malesci, Luigi Laghi, Silvio Danese, Stefania Vetrano

Sci Rep. 2022; 12: 381. Published online 2022 Jan 10. doi: 10.1038/s41598-021-03787-7

PMCID:: PMC8748819

Abstract Article PDF–6.1M

Select item 76833466.

Autocrine negative feedback regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT

Anna Sofie Husted, Jeppe H. Ekberg, Emma Tripp, Tinne A.D. Nissen, Stijn Meijnikman, Shannon L. O'Brien, Trond Ulven, Yair Acherman, Sjoerd C. Bruin, Max Nieuwdorp, Zach Gerhart-Hines, Davide Calebiro, Lars O. Dragsted, Thue W. Schwartz

Mol Metab. 2020 Dec; 42: 101103. Published online 2020 Oct 19. doi: 10.1016/j.molmet.2020.101103

PMCID:: PMC7683346

Abstract Article PDF–1.9M

Select item 73322227.

Omega-3 fatty acids activate ciliary FFAR4 to control adipogenesis

Keren I. Hilgendorf, Carl T. Johnson, Anja Mezger, Selena L. Rice, Alessandra M. Norris, Janos Demeter, William J. Greenleaf, Jeremy F. Reiter, Daniel Kopinke, Peter K. Jackson

Cell. Author manuscript; available in PMC 2020 Nov 27.

Published in final edited form as: Cell. 2019 Nov 27; 179(6): 1289–1305.e21. Published online 2019 Nov 21. doi: 10.1016/j.cell.2019.11.005

PMCID:: PMC7332222

Abstract Article PDF–3.7M

Select item 70810538.

Carboxy-Terminal Phosphoregulation of the Long Splice Isoform of Free-Fatty Acid Receptor-4 Mediates β-Arrestin Recruitment and Signaling to ERK1/2

Ilya S. Senatorov, Ameneh Cheshmehkani, Rebecca N. Burns, Kirti Singh, Nader H. Moniri

Mol Pharmacol. 2020 May; 97(5): 304–313. Published online 2020 May. doi: 10.1124/mol.119.117697

PMCID:: PMC7081053

Abstract Article PDF–1.1M

Select item 64868259.

FFAR4 Is Involved in Regulation of Neurotensin Release From Neuroendocrine Cells and Male C57BL/6 Mice

Jing Li, Jun Song, Xian Li, Stephanie B Rock, Heather F Sinner, Heidi L Weiss, Todd Weiss, Courtney M Townsend, Jr, Tianyan Gao, B Mark Evers

Endocrinology. 2018 Aug; 159(8): 2939–2952. Published online 2018 May 22. doi: 10.1210/en.2018-00284

PMCID:: PMC6486825

Abstract Article

Select item 644971110.

G-Protein-Coupled Receptor 120 Mediates DHA-Induced Apoptosis by Regulating IP3R, ROS and, ER Stress Levels in Cisplatin-Resistant Cancer Cells

Jong-Il Shin, Yong-Joon Jeon, Sol Lee, Yoon Gyeong Lee, Ji Beom Kim, Kyungho Lee

Mol Cells. 2019 Mar 31; 42(3): 252–261. Published online 2019 Feb 13. doi: 10.14348/molcells.2019.2440

PMCID:: PMC6449711

Abstract Article PDF–1.3M

Select item 641529511.

Free-fatty acid receptor-4 (GPR120): cellular and molecular function and its role in metabolic disorders

Nader H. Moniri

Biochem Pharmacol. Author manuscript; available in PMC 2019 Mar 13.

Published in final edited form as: Biochem Pharmacol. 2016 Jun 15; 110-111: 1–15. Published online 2016 Jan 28. doi: 10.1016/j.bcp.2016.01.021

PMCID:: PMC6415295

Abstract Article PDF–1.0M

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Fatty acid receptor GPR120 promotes breast cancer chemoresistance by upregulating ABC transporters expression and fatty acid synthesis

Xue Wang, Songbing He, Yuting Gu, Qiwei Wang, Xiao Chu, Min Jin, Liang Xu, Qiong Wu, Qianjun Zhou, Bei Wang, Yanyun Zhang, Hui Wang, Leizhen Zheng

EBioMedicine. 2019 Feb; 40: 251–262. Published online 2019 Feb 6. doi: 10.1016/j.ebiom.2018.12.037

PMCID:: PMC6413582

Abstract Article PDF–4.0M

Select item 635532713.

Protective role of GPR120 in the maintenance of pregnancy by promoting decidualization via regulation of glucose metabolism

Jiefang Huang, Mingxing Xue, Jie Zhang, Hongshuang Yu, Yuting Gu, Meirong Du, Wenfeng Ye, Bing Wan, Min Jin, Yanyun Zhang

EBioMedicine. 2019 Jan; 39: 540–551. Published online 2018 Dec 18. doi: 10.1016/j.ebiom.2018.12.019

PMCID:: PMC6355327

Abstract Article PDF–3.3M

Select item 609109814.

GPR120 is an important inflammatory regulator in the development of osteoarthritis

Yuanfeng Chen, Dan Zhang, Ki Wai Ho, Sien Lin, Wade Chun-Wai Suen, Huantian Zhang, Zhengang Zha, Gang Li, Po Sing Leung

Arthritis Res Ther. 2018; 20: 163. Published online 2018 Aug 3. doi: 10.1186/s13075-018-1660-6

PMCID:: PMC6091098

Abstract Article PDF–5.0M

Select item 511854615.

The lipid sensor GPR120 promotes brown fat activation and FGF21 release from adipocytes

Tania Quesada-López, Rubén Cereijo, Jean-Valery Turatsinze, Anna Planavila, Montserrat Cairó, Aleix Gavaldà-Navarro, Marion Peyrou, Ricardo Moure, Roser Iglesias, Marta Giralt, Decio L. Eizirik, Francesc Villarroya

Nat Commun. 2016; 7: 13479. Published online 2016 Nov 17. doi: 10.1038/ncomms13479

PMCID:: PMC5118546

Abstract Article PDF–2.3M

Select item 503470316.

Positive and Negative Cross-Talk between Lysophosphatidic Acid Receptor 1, Free Fatty Acid Receptor 4, and Epidermal Growth Factor Receptor in Human Prostate Cancer Cells

Mandi M. Hopkins, Ze Liu, Kathryn E. Meier

J Pharmacol Exp Ther. 2016 Oct; 359(1): 124–133. Published online 2016 Oct. doi: 10.1124/jpet.116.233379

PMCID:: PMC5034703

Abstract Article PDF–1.7M

Select item 482416017.

A novel anti-inflammatory role of GPR120 in intestinal epithelial cells

Arivarasu N. Anbazhagan, Shubha Priyamvada, Tarunmeet Gujral, Sumit Bhattacharyya, Waddah A. Alrefai, Pradeep K. Dudeja, Alip Borthakur

Am J Physiol Cell Physiol. 2016 Apr 1; 310(7): C612–C621. Published online 2016 Jan 20. doi: 10.1152/ajpcell.00123.2015

PMCID:: PMC4824160

Abstract Article

Select item 450036418.

Characterizing pharmacological ligands to study the long-chain fatty acid receptors GPR40/FFA1 and GPR120/FFA4

G Milligan, E Alvarez-Curto, K R Watterson, T Ulven, B D Hudson

Br J Pharmacol. 2015 Jul; 172(13): 3254–3265. Published online 2015 Feb 27. doi: 10.1111/bph.12879

PMCID:: PMC4500364

Abstract Article PDF–732K

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Functional Analysis of Free Fatty Acid Receptor GPR120 in Human Eosinophils: Implications in Metabolic Homeostasis

Yasunori Konno, Shigeharu Ueki, Masahide Takeda, Yoshiki Kobayashi, Mami Tamaki, Yuki Moritoki, Hajime Oyamada, Masamichi Itoga, Hiroyuki Kayaba, Ayumi Omokawa, Makoto Hirokawa

PLoS One. 2015; 10(3): e0120386. Published online 2015 Mar 19. doi: 10.1371/journal.pone.0120386