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Select item 115159241.

FOXO1‐NCOA4 Axis Contributes to Cisplatin‐Induced Cochlea Spiral Ganglion Neuron Ferroptosis via Ferritinophagy

Xue Wang, Lei Xu, Yu Meng, Fang Chen, Jinzhu Zhuang, Man Wang, Weibin An, Yuechen Han, Bo Chu, Renjie Chai, Wenwen Liu, Haibo Wang

Adv Sci (Weinh) 2024 Oct; 11(40): 2402671. Published online 2024 Aug 29. doi: 10.1002/advs.202402671

PMCID:: PMC11515924

Abstract Article PDF–41M

Select item 108856092.

Regulation of NCOA4-mediated iron recycling ameliorates paraquat-induced lung injury by inhibiting ferroptosis

Jing Du, Lingyan Yu, Xinyi Yang, Fangchun Shao, Jun Xia, Weidong Jin, Yinhao Zhang, Guojie Lei, Ying Wang, Yanchun Li, Jun Zhang

Cell Commun Signal. 2024; 22: 146. Published online 2024 Feb 22. doi: 10.1186/s12964-024-01520-1

PMCID:: PMC10885609

Abstract Article PDF–16M

Select item 107693503.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 107607944.

Nrf2 protects against cartilage endplate degeneration through inhibiting NCOA4-mediated ferritinophagy

Zhenkai Ma, Hui Lu, Xuemin Feng, Ting Du, Jianhua Li, Qiang Zhang, Xindong Gu, Yuandong Shao, Xingzhi Jing, Cheng Su

Int J Mol Med. 2024 Feb; 53(2): 15. Published online 2023 Dec 7. doi: 10.3892/ijmm.2023.5339

PMCID:: PMC10760794

Abstract Article PDF–11M

Select item 102834185.

ATM orchestrates ferritinophagy and ferroptosis by phosphorylating NCOA4

Hao Wu, Qian Liu, Xinyi Shan, Weihua Gao, Quan Chen

Autophagy. 2023; 19(7): 2062–2077. Published online 2023 Feb 8. doi: 10.1080/15548627.2023.2170960

PMCID:: PMC10283418

Abstract Article PDF–5.7M

Select item 101048926.

Mycobacterium tuberculosis hijacks host TRIM21- and NCOA4-dependent ferritinophagy to enhance intracellular growth

Youchao Dai, Chuanzhi Zhu, Wei Xiao, Kaisong Huang, Xin Wang, Chenyan Shi, Dachuan Lin, Huihua Zhang, Xiaoqian Liu, Bin Peng, Yi Gao, Cui Hua Liu, Baoxue Ge, Stefan H.E. Kaufmann, Carl G. Feng, Xinchun Chen, Yi Cai

J Clin Invest. 2023 Apr 17; 133(8): e159941. Published online 2023 Apr 17. doi: 10.1172/JCI159941

PMCID:: PMC10104892

Abstract Article PDF–10M

Select item 95368427.

Selective optogenetic activation of Na_V1.7–expressing afferents in Na_V1.7-ChR2 mice induces nocifensive behavior without affecting responses to mechanical and thermal stimuli

Toyoaki Maruta, Kotaro Hidaka, Satoshi Kouroki, Tomohiro Koshida, Mio Kurogi, Yohko Kage, Seiya Mizuno, Tetsuro Shirasaka, Toshihiko Yanagita, Satoru Takahashi, Ryu Takeya, Isao Tsuneyoshi

PLoS One. 2022; 17(10): e0275751. Published online 2022 Oct 6. doi: 10.1371/journal.pone.0275751

PMCID:: PMC9536842

Abstract Article PDF–1.4M

Select item 93342698.

The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages

Jie Wu, Qinjie Liu, Xufei Zhang, Miaomiao Tan, Xuanheng Li, Peizhao Liu, Lei Wu, Fan Jiao, Zhaoyu Lin, Xiuwen Wu, Xin Wang, Yun Zhao, Jianan Ren

Cell Death Dis. 2022 Jul; 13(7): 653. Published online 2022 Jul 28. doi: 10.1038/s41419-022-05115-x

PMCID:: PMC9334269

Abstract Article PDF–9.3M

Select item 88324619.

DYRK1a mediates BAFF-induced noncanonical NF-κB activation to promote autoimmunity and B-cell leukemogenesis

Yanchuan Li, Xiaoping Xie, Zuliang Jie, Lele Zhu, Jin-Young Yang, Chun-Jung Ko, Tianxiao Gao, Antrix Jain, Sung Yun Jung, Natalia Baran, Marina Y. Konopleva, Xuhong Cheng, Shao-Cong Sun

Blood. 2021 Dec 9; 138(23): 2360–2371. doi: 10.1182/blood.2021011247

PMCID:: PMC8832461

Abstract Article

Select item 845012310.

Curcumol inhibits ferritinophagy to restrain hepatocyte senescence through YAP/NCOA4 in non‐alcoholic fatty liver disease

Xiaoyu Qi, Anping Song, Mingyue Ma, Peipei Wang, Xinbei Zhang, Chunfeng Lu, Junxiu Zhang, Shuguo Zheng, Huanhuan Jin

Cell Prolif. 2021 Sep; 54(9): e13107. Published online 2021 Aug 3. doi: 10.1111/cpr.13107

PMCID:: PMC8450123

Abstract Article PDF–2.7M

Select item 838659711.

ATG7 is essential for secretion of iron from ameloblasts and normal growth of murine incisors during aging

Supawadee Sukseree, Uwe Yacine Schwarze, Reinhard Gruber, Florian Gruber, Maria Quiles Del Rey, Joseph D. Mancias, John D. Bartlett, Erwin Tschachler, Leopold Eckhart

Autophagy. 2020; 16(10): 1851–1857. Published online 2020 Jan 3. doi: 10.1080/15548627.2019.1709764

PMCID:: PMC8386597

Abstract Article PDF–3.2M

Select item 793877012.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 792801513.

NCOA4-mediated ferritinophagy in macrophages is crucial to sustain erythropoiesis in mice

Antonella Nai, Maria Rosa Lidonnici, Giorgia Federico, Mariateresa Pettinato, Violante Olivari, Federica Carrillo, Simonetta Geninatti Crich, Giuliana Ferrari, Clara Camaschella, Laura Silvestri, Francesca Carlomagno

Haematologica. 2021 Mar 1; 106(3): 795–805. Published online 2020 Feb 27. doi: 10.3324/haematol.2019.241232

PMCID:: PMC7928015

Abstract Article PDF–2.1M

Select item 773515814.

NCOA4 is regulated by HIF and mediates mobilization of murine hepatic iron stores after blood loss

Xiuqi Li, Larisa Lozovatsky, Abitha Sukumaran, Luis Gonzalez, Anisha Jain, Dong Liu, Nadia Ayala-Lopez, Karin E. Finberg

Blood. 2020 Dec 3; 136(23): 2691–2702. Prepublished online 2020 Jul 13. doi: 10.1182/blood.2020006321

PMCID:: PMC7735158

Abstract Article

Select item 741599115.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 714768816.

Spatiotemporal gene expression patterns reveal molecular relatedness between retinal laminae

Danye Jiang, Courtney A. Burger, Anna Casasent, Nicholas E. Albrecht, Fenge Li, Melanie A. Samuel

J Comp Neurol. Author manuscript; available in PMC 2021 Apr 1.

Published in final edited form as: J Comp Neurol. 2020 Apr 1; 528(5): 729–755. Published online 2019 Oct 31. doi: 10.1002/cne.24784

PMCID:: PMC7147688

Abstract Article PDF–4.0M

Select item 694937717.

Microbial metabolite signaling is required for systemic iron homeostasis.

Nupur K. Das, Andrew J. Schwartz, Gabrielle Barthel, Naohiro Inohara, Qing Liu, Amanda Sankar, David Hill, Xiaoya Ma, Olivia Lamberg, Matthew K. Schnizlein, Juan L Arqués, Jason R. Spence, Gabriel Nunez, Andrew D. Patterson, Duxin Sun, Vincent B. Young, Yatrik M. Shah

Cell Metab. Author manuscript; available in PMC 2021 Jan 7.

Published in final edited form as: Cell Metab. 2020 Jan 7; 31(1): 115–130.e6. Published online 2019 Nov 7. doi: 10.1016/j.cmet.2019.10.005

PMCID:: PMC6949377

Abstract Article PDF–2.5M

Select item 660109418.

NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms

Naiara Santana-Codina, Sebastian Gableske, Maria Quiles del Rey, Beata Małachowska, Mark P. Jedrychowski, Douglas E. Biancur, Paul J. Schmidt, Mark D. Fleming, Wojciech Fendler, J. Wade Harper, Alec C. Kimmelman, Joseph D. Mancias

Haematologica. 2019 Jul; 104(7): 1342–1354. Prepublished online 2019 Jan 10. doi: 10.3324/haematol.2018.204123

PMCID:: PMC6601094

Abstract Article PDF–4.0M

Select item 629804019.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 579538820.

The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes

Fan Liu, Philip Lössl, Beverley M. Rabbitts, Robert S. Balaban, Albert J. R. Heck

Mol Cell Proteomics. 2018 Feb; 17(2): 216–232. Published online 2017 Dec 8. doi: 10.1074/mcp.RA117.000470

PMCID:: PMC5795388

Abstract Article PDF–4.4M

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