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Items: 1 to 20 of 72

1.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek
Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x
PMCID:
PMC11148184
AbstractArticlePDF–8.1M
2.
The role of Bach2 in regulating CD8 + T cell development and function
Xinyu Weng, Min Zheng, Yanning Liu, Guohua Lou
Cell Commun Signal. 2024; 22: 169. Published online 2024 Mar 8. doi: 10.1186/s12964-024-01551-8
PMCID:
PMC10921639
AbstractArticlePDF–1.0M
3.
The rs11755527 polymorphism in the BACH2 gene and type 1 diabetes mellitus: case control study in a Brazilian population
Cristine Dieter, Natália Emerim Lemos, Luiza Emy Dorfman, Guilherme Coutinho Kullmann Duarte, Taís Silveira Assmann, Daisy Crispim
Arch Endocrinol Metab. 2020 Mar-Apr; 64(2): 138–143. Published online 2020 Mar 18. doi: 10.20945/2359-3997000000214
PMCID:
PMC10118942
AbstractArticlePDF–154K
4.
BACH2 restricts NK cell maturation and function, limiting immunity to cancer metastasis
Charlotte J. Imianowski, Sarah K. Whiteside, Teresa Lozano, Alexander C. Evans, Jayme D. Benson, Christina J.F. Courreges, Firas Sadiyah, Colleen M. Lau, Nordin D. Zandhuis, Francis M. Grant, Martijn J. Schuijs, Panagiota Vardaka, Paula Kuo, Elizabeth J. Soilleux, Jie Yang, Joseph C. Sun, Tomohiro Kurosaki, Klaus Okkenhaug, Timotheus Y.F. Halim, Rahul Roychoudhuri
J Exp Med. 2022 Dec 5; 219(12): e20211476. Published online 2022 Sep 30. doi: 10.1084/jem.20211476
PMCID:
PMC9529614
AbstractArticlePDF–5.6M
5.
Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling
Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser
Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151
PMCID:
PMC9105235
AbstractArticlePDF–5.8M
6.
CRISPR/Cas9-mediated insertion of HIV LTR within BACH2 promotes expansion of T regulatory-like cells
Michelle L. Christian, Michael J. Dapp, Samuel C. Scharffenberger, Hank Jones, Chaozhong Song, Lisa M. Frenkel, Anthony Krumm, James I. Mullins, David J. Rawlings
J Immunol. Author manuscript; available in PMC 2023 Apr 1.
Published in final edited form as: J Immunol. 2022 Apr 1; 208(7): 1700–1710. Published online 2022 Mar 9. doi: 10.4049/jimmunol.2100491
PMCID:
PMC8976747
AbstractArticlePDF–1.6M
7.
BACH2 inhibition reverses β cell failure in type 2 diabetes models
Jinsook Son, Hongxu Ding, Thomas B. Farb, Alexander M. Efanov, Jiajun Sun, Julie L. Gore, Samreen K. Syed, Zhigang Lei, Qidi Wang, Domenico Accili, Andrea Califano
J Clin Invest. 2021 Dec 15; 131(24): e153876. Published online 2021 Dec 15. doi: 10.1172/JCI153876
PMCID:
PMC8670842
AbstractArticlePDF–12M
8.
Polymorphism in BACH2 gene is a marker of polyglandular autoimmunity
Marta Fichna, Magdalena Żurawek, Bartosz Słomiński, Marta Sumińska, Agata Czarnywojtek, Natalia Rozwadowska, Piotr Fichna, Małgorzata Myśliwiec, Marek Ruchała
Endocrine. 2021; 74(1): 72–79. Published online 2021 May 8. doi: 10.1007/s12020-021-02743-9
PMCID:
PMC8440266
AbstractArticlePDF–463K
9.
Whole genome sequencing identifies variants associated with sarcoidosis in a family with a high prevalence of sarcoidosis
Daan Fritz, Bart Ferwerda, Matthijs C. Brouwer, Diederik van de Beek
Clin Rheumatol. 2021; 40(9): 3735–3743. Published online 2021 Apr 27. doi: 10.1007/s10067-021-05684-w
PMCID:
PMC8357727
AbstractArticlePDF–365K
10.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
11.
Up-regulated circBACH2 contributes to cell proliferation, invasion, and migration of triple-negative breast cancer
Xinxing Wang, Bingjian Xue, Yujie Zhang, Guangcheng Guo, Xin Duan, Dongwei Dou
Cell Death Dis. 2021 May; 12(5): 412. Published online 2021 Apr 19. doi: 10.1038/s41419-021-03684-x
PMCID:
PMC8055688
AbstractArticlePDF–3.8M
12.
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale
Science. Author manuscript; available in PMC 2021 Mar 30.
Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239
PMCID:
PMC8009048
AbstractArticlePDF–2.6M
13.
A conserved acetylation switch enables pharmacological control of tubby-like protein stability
Evan M. Kerek, Kevin H. Yoon, Shu Y. Luo, Jerry Chen, Robert Valencia, Olivier Julien, Andrew J. Waskiewicz, Basil P. Hubbard
J Biol Chem. 2021 Jan-Jun; 296: 100073. Published online 2020 Nov 23. doi: 10.1074/jbc.RA120.015839
PMCID:
PMC7948452
AbstractArticlePDF–3.6M
14.
BACH2‐mediated FOS confers cytarabine resistance via stromal microenvironment alterations in pediatric ALL
Han Zhang, Ruidong Zhang, Xueling Zheng, Ming Sun, Jia Fan, Chunlian Fang, Xin Tian, Huyong Zheng
Cancer Sci. 2021 Mar; 112(3): 1235–1250. Published online 2021 Jan 22. doi: 10.1111/cas.14792
PMCID:
PMC7935781
AbstractArticlePDF–3.1M
15.
Bach2 overexpression represses Th9 cell differentiation by suppressing IRF4 expression in systemic lupus erythematosus
Yujun Sheng, Jiali Zhang, Keke Li, Hongyan Wang, Wenjun Wang, Leilei Wen, Jinping Gao, Xianfa Tang, Huayang Tang, He Huang, Minglong Cai, Tao Yuan, Lu Liu, Xiaodong Zheng, Zhengwei Zhu, Yong Cui
FEBS Open Bio. 2021 Feb; 11(2): 395–403. Published online 2020 Dec 22. doi: 10.1002/2211-5463.13050
Retraction in:
FEBS Open Bio. 2024 Dec; 14(12): 2117.
PMCID:
PMC7876501
AbstractArticle
16.
Interaction of BACH2 with FUS promotes malignant progression of glioma cells via the TSLNC8–miR‐10b‐5p–WWC3 pathway
Yang Yang, Xiaobai Liu, Jian Zheng, Yixue Xue, Libo Liu, Jun Ma, Ping Wang, Chunqing Yang, Di Wang, Lianqi Shao, Xuelei Ruan, Yunhui Liu
Mol Oncol. 2020 Nov; 14(11): 2936–2959. Published online 2020 Sep 26. doi: 10.1002/1878-0261.12795
PMCID:
PMC7607167
AbstractArticlePDF–23M
17.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
18.
The Critical Role of Bach2 in Shaping the Balance between CD4+ T Cell Subsets in Immune-Mediated Diseases
Lingyi Yang, Shuli Chen, Qiuyu Zhao, Ying Sun, Hong Nie
Mediators Inflamm. 2019; 2019: 2609737. Published online 2019 Dec 30. doi: 10.1155/2019/2609737
PMCID:
PMC7012215
AbstractArticlePDF–391K
19.
Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity
Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller
Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119
PMCID:
PMC6942044
AbstractArticlePDF–10M
20.
Variants in the BACH2 and CLEC16A gene might be associated with susceptibility to insulin‐triggered type 1 diabetes
Hiroshi Onuma, Ryoichi Kawamura, Yasuharu Tabara, Masakatsu Yamashita, Jun Ohashi, Eiji Kawasaki, Akihisa Imagawa, Yuya Yamada, Daisuke Chujo, Kenji Takahashi, Tadashi Suehiro, Yasunori Takata, Haruhiko Osawa, Hideichi Makino
J Diabetes Investig. 2019 Nov; 10(6): 1447–1453. Published online 2019 May 14. doi: 10.1111/jdi.13057
PMCID:
PMC6825945
AbstractArticlePDF–403K

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