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Select item 114010341.

Proximity labeling reveals dynamic changes in the SQSTM1 protein network

Alejandro N. Rondón-Ortiz, Lushuang Zhang, Peter E.A. Ash, Avik Basu, Sambhavi Puri, Sophie J.F. van der Spek, Zihan Wang, Luke Dorrian, Andrew Emili, Benjamin Wolozin

J Biol Chem. 2024 Sep; 300(9): 107621. Published online 2024 Aug 3. doi: 10.1016/j.jbc.2024.107621

PMCID:: PMC11401034

Abstract Article PDF–5.4M

Select item 113799752.

ASIC1/RIP1 accelerates atherosclerosis via disrupting lipophagy

Yuan-Mei Wang, Huang Tang, Ya-Jie Tang, Juan Liu, Yu-Fang Yin, Ya-Ling Tang, Yao-Guang Feng, Hong-Feng Gu

J Adv Res. 2024 Sep; 63: 195–206. Published online 2023 Nov 4. doi: 10.1016/j.jare.2023.11.004

PMCID:: PMC11379975

Abstract Article PDF–4.2M

Select item 113735993.

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway

Elena Prosdocimi, Veronica Carpanese, Luca Matteo Todesca, Tatiana Varanita, Magdalena Bachmann, Margherita Festa, Daniele Bonesso, Mireia Perez-Verdaguer, Andrea Carrer, Angelo Velle, Roberta Peruzzo, Silvia Muccioli, Davide Doni, Luigi Leanza, Paola Costantini, Frank Stein, Mandy Rettel, Antonio Felipe, Michael J. Edwards, Erich Gulbins, Laura Cendron, Chiara Romualdi, Vanessa Checchetto, Ildiko Szabo

Sci Adv. 2024 Sep 6; 10(36): eadn9361. Published online 2024 Sep 4. doi: 10.1126/sciadv.adn9361

PMCID:: PMC11373599

Abstract Article PDF–11M

Select item 113159294.

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex

Marisa Bedir, Emily Outwin, Rita Colnaghi, Lydia Bassett, Iga Abramowicz, Mark O’Driscoll

EMBO Rep. 2024 Aug; 25(8): 3432–3455. Published online 2024 Jun 28. doi: 10.1038/s44319-024-00184-9

PMCID:: PMC11315929

Abstract Article PDF–3.4M

Select item 112969145.

DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples

Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang

J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.

Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832

PMCID:: PMC11296914

Abstract Article PDF–1.7M

Select item 112897376.

The Interferon-Stimulated Gene RIPK1 Regulates Cancer Cell Intrinsic and Extrinsic Resistance to Immune Checkpoint Blockade

Lisa Cucolo, Qingzhou Chen, Jingya Qiu, Yongjun Yu, Max Klapholz, Krista Budinich, Zhaojun Zhang, Yue Shao, Igor E. Brodsky, Martha S. Jordan, D. Gary Gilliland, Nancy R. Zhang, Junwei Shi, Andy J. Minn

Immunity. Author manuscript; available in PMC 2024 Jul 31.

Published in final edited form as: Immunity. 2022 Apr 12; 55(4): 671–685.e10. doi: 10.1016/j.immuni.2022.03.007

PMCID:: PMC11289737

Abstract Article PDF–3.5M

Select item 111816677.

The deubiquitinating protein OTUD6B promotes lung adenocarcinoma progression by stabilizing RIPK1

Miaomiao Yang, Yujie Wei, Xin He, Changwei Xia

Biol Direct. 2024; 19: 46. Published online 2024 Jun 16. doi: 10.1186/s13062-024-00489-8

PMCID:: PMC11181667

Abstract Article PDF–7.6M

Select item 111589598.

Modulation of RIP1 ubiquitylation and distribution by MeBS to sensitize cancer cells to tumor necrosis factor α‐induced apoptosis

Seungseob Kim, Nobumichi Ohoka, Keiichiro Okuhira, Kimie Sai, Tomoko Nishimaki‐Mogami, Mikihiko Naito

Cancer Sci. 2010 Nov; 101(11): 2425–2429. Published online 2010 Jul 31. doi: 10.1111/j.1349-7006.2010.01697.x

PMCID:: PMC11158959

Abstract Article PDF–365K

Select item 110727669.

Cell adhesion tunes inflammatory TPL2 kinase signal transduction

Maria Vougioukalaki, Konstantina Georgila, Emmanouil I. Athanasiadis, Aristides G. Eliopoulos

Cell Mol Life Sci. 2022 Mar; 79(3): 156. Published online 2022 Feb 26. doi: 10.1007/s00018-022-04130-7

PMCID:: PMC11072766

Abstract Article PDF–2.1M

Select item 1102417910.

TAK1 inhibition leads to RIPK1-dependent apoptosis in immune-activated cancers

Helene Damhofer, Tülin Tatar, Benjamin Southgate, Scott Scarneo, Karl Agger, Daria Shlyueva, Lene Uhrbom, Gillian M. Morrison, Philip F. Hughes, Timothy Haystead, Steven M. Pollard, Kristian Helin

Cell Death Dis. 2024 Apr; 15(4): 273. Published online 2024 Apr 17. doi: 10.1038/s41419-024-06654-1

PMCID:: PMC11024179

Abstract Article PDF–6.6M

Select item 1071619211.

Elevated peripheral levels of receptor-interacting protein kinase 1 (RIPK1) and IL-8 as biomarkers of human amyotrophic lateral sclerosis

Jun Wei, Min Li, Zhi Ye, Xinqian Hu, Xiaoyan He, Jia Wang, Gaofeng Chen, Chengyu Zou, Daichao Xu, Hongbing Zhang, Junying Yuan, Yunhong Zha

Signal Transduct Target Ther. 2023; 8: 451. Published online 2023 Dec 13. doi: 10.1038/s41392-023-01713-z

PMCID:: PMC10716192

Abstract Article PDF–2.7M

Select item 1056878512.

Caspase 6 promotes innate immune activation by functional crosstalk between RIPK1-IκBα axis in liver inflammation

Yuanbang Lin, Mingwei Sheng, Hua Qin, Peng Zhang, Chunli Wang, Wei Fu, Xiangjun Meng, Duowei Wang, Yachao Hou

Cell Commun Signal. 2023; 21: 282. Published online 2023 Oct 12. doi: 10.1186/s12964-023-01287-x

PMCID:: PMC10568785

Abstract Article PDF–12M

Select item 1040683613.

CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma

You Heng Chuah, Emmy Xue Yun Tay, Oleg V. Grinchuk, Jeehyun Yoon, Jia Feng, Srinivasaraghavan Kannan, Matius Robert, Rekha Jakhar, Yajing Liang, Bernice Woon Li Lee, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw M. Sobota, Guang Lu, Boon Chuan Low, Karen Carmelina Crasta, Chandra Shekhar Verma, Zhewang Lin, Derrick Sek Tong Ong

Cell Death Differ. 2023 Aug; 30(8): 1973–1987. Published online 2023 Jul 19. doi: 10.1038/s41418-023-01192-3

PMCID:: PMC10406836

Abstract Article PDF–5.9M

Select item 1033627114.

TSG101 Physically Interacts with Linear Ubiquitin Chain Assembly Complex (LUBAC) and Upregulates the TNFα-Induced NF-κB Activation

Eunju Kim, Hyunchu Cho, Gaeul Lee, Heawon Baek, In Young Lee, Eui-Ju Choi

Mol Cells. 2023 Jul 31; 46(7): 430–440. Published online 2023 Jul 31. doi: 10.14348/molcells.2023.0026

PMCID:: PMC10336271

Abstract Article PDF–1.9M

Select item 1028900415.

O-GlcNAcylation of RIPK1 rescues red blood cells from necroptosis

Junghwa Seo, Yeolhoe Kim, Suena Ji, Han Byeol Kim, Hyeryeon Jung, Eugene C. Yi, Yong-ho Lee, Injae Shin, Won Ho Yang, Jin Won Cho

Front Immunol. 2023; 14: 1160490. Published online 2023 Jun 9. doi: 10.3389/fimmu.2023.1160490

PMCID:: PMC10289004

Abstract Article PDF–17M

Select item 1024438316.

IKK-mediated TRAF6 and RIPK1 interaction stifles cell death complex assembly leading to the suppression of TNF-α-induced cell death

Choong-Sil Lee, Gyuho Hwang, Young Woo Nam, Chi Hyun Hwang, Jaewhan Song

Cell Death Differ. 2023 Jun; 30(6): 1575–1584. Published online 2023 Apr 21. doi: 10.1038/s41418-023-01161-w

PMCID:: PMC10244383

Abstract Article PDF–2.8M

Select item 1023742217.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233