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Items: 1 to 20 of 28

1.
Immune checkpoint gene signature assesses immune infiltration profiles in bladder cancer and identifies KRT23 as an immunotherapeutic target
Dongshan Chen, Haoyuan Cao, Xiang Zheng, Haojun Wang, Zengchi Han, Wei Wang
BMC Cancer. 2024; 24: 1024. Published online 2024 Aug 19. doi: 10.1186/s12885-024-12790-w
PMCID:
PMC11331755
AbstractArticlePDF–16M
2.
DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC
Yejinpeng Wang, Lingao Ju, Gang Wang, Kaiyu Qian, Wan Jin, Mingxing Li, Jingtian Yu, Yiliang Shi, Yongzhi Wang, Yi Zhang, Yu Xiao, Xinghuan Wang
Nat Commun. 2023; 14: 2421. Published online 2023 Apr 27. doi: 10.1038/s41467-023-38160-x
PMCID:
PMC10140023
AbstractArticlePDF–5.8M
3.
EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation
Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing
Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6
PMCID:
PMC8748958
AbstractArticlePDF–3.0M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer
Hantao Wang, Junjie Xing, Wei Wang, Guifen Lv, Haiyan He, Yeqing Lu, Mei Sun, Haiyan Chen, Xu Li
Front Cell Dev Biol. 2020; 8: 601502. Published online 2021 Feb 11. doi: 10.3389/fcell.2020.601502
PMCID:
PMC7905040
AbstractArticlePDF–3.2M
6.
The Overexpression of Keratin 23 Promotes Migration of Ovarian Cancer via Epithelial-Mesenchymal Transition
Meng Ren, Yan Gao, Qi Chen, Hongyu Zhao, Xiaoting Zhao, Wentao Yue
Biomed Res Int. 2020; 2020: 8218735. Published online 2020 Nov 1. doi: 10.1155/2020/8218735
PMCID:
PMC7652601
AbstractArticlePDF–2.7M
7.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
8.
A Genome-Wide Knockout Screen in Human Macrophages Identified Host Factors Modulating Salmonella Infection
Amy T. Y. Yeung, Yoon Ha Choi, Amy H. Y. Lee, Christine Hale, Hannes Ponstingl, Derek Pickard, David Goulding, Mark Thomas, Erin Gill, Jong Kyoung Kim, Allan Bradley, Robert E. W. Hancock, Gordon Dougan
mBio. 2019 Sep-Oct; 10(5): e02169-19. Published online 2019 Oct 8. doi: 10.1128/mBio.02169-19
PMCID:
PMC6786873
AbstractArticlePDF–2.2M
9.
Identification of Keratin 23 as a Hepatitis C Virus-Induced Host Factor in the Human Liver
Volker Kinast, Stefan L. Leber, Richard J. P. Brown, Gabrielle Vieyres, Patrick Behrendt, Constanze Eßbach, Pavel Strnad, Florian W. R. Vondran, Markus Cornberg, Cora Wex, Thomas Pietschmann, Johannes Haybaeck, Daniel Todt, Eike Steinmann
Cells. 2019 Jun; 8(6): 610. Published online 2019 Jun 18. doi: 10.3390/cells8060610
PMCID:
PMC6628310
AbstractArticlePDF–5.8M
10.
Keratin 23 is a PPARA-dependent, MYC-amplified oncogene that promotes hepatocyte proliferation
Donghwan Kim, Chad N. Brocker, Shogo Takahashi, Tomoki Yagai, Taehyeong Kim, Guomin Xie, DR. Hua Wang, Aijuan Qu, Frank J. Gonzalez
Hepatology. Author manuscript; available in PMC 2020 Jul 1.
Published in final edited form as: Hepatology. 2019 Jul; 70(1): 154–167. Published online 2019 Mar 20. doi: 10.1002/hep.30530
PMCID:
PMC6597269
AbstractArticlePDF–3.1M
11.
Parkinson’s disease-associated LRRK2-G2019S mutant acts through regulation of SERCA activity to control ER stress in astrocytes
Jee Hoon Lee, Ji-hye Han, Hyunmi Kim, Sang Myun Park, Eun-hye Joe, Ilo Jou
Acta Neuropathol Commun. 2019; 7: 68. Published online 2019 May 2. doi: 10.1186/s40478-019-0716-4
PMCID:
PMC6498585
AbstractArticlePDF–6.9M
12.
Phosphoprotein Keratin 23 accumulates in MSS but not MSI colon cancers in vivo and impacts viability and proliferation in vitro
Karin Birkenkamp-Demtroder, Francisco Mansilla, Flemming Brandt Sørensen, Mogens Kruhøffer, Teresa Cabezón, Lise Lotte Christensen, Lauri A. Aaltonen, Hein W. Verspaget, Torben Falck Ørntoft
Mol Oncol. 2007 Sep; 1(2): 181–195. Published online 2007 Jun 3. doi: 10.1016/j.molonc.2007.05.005
PMCID:
PMC5543893
AbstractArticlePDF–1.5M
13.
LPS-TLR4 Pathway Mediates Ductular Cell Expansion in Alcoholic Hepatitis
Gemma Odena, Jiegen Chen, Juan Jose Lozano, Jose Altamirano, Daniel Rodrigo-Torres, Silvia Affo, Oriol Morales-Ibanez, Hiroshi Matsushita, Jian Zou, Raluca Dumitru, Juan Caballeria, Pere Gines, Vicente Arroyo, Min You, Pierre-Emmanuel Rautou, Dominique Valla, Fulton Crews, Ekihiro Seki, Pau Sancho-Bru, Ramon Bataller
Sci Rep. 2016; 6: 35610. Published online 2016 Oct 18. doi: 10.1038/srep35610
PMCID:
PMC5067590
AbstractArticlePDF–2.1M
14.
SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling
Paul R. Elliott, Derek Leske, Matous Hrdinka, Katrin Bagola, Berthe K. Fiil, Stephen H. McLaughlin, Jane Wagstaff, Norbert Volkmar, John C. Christianson, Benedikt M. Kessler, Stefan M.V. Freund, David Komander, Mads Gyrd-Hansen
Mol Cell. 2016 Sep 15; 63(6): 990–1005. doi: 10.1016/j.molcel.2016.08.001
PMCID:
PMC5031558
AbstractArticlePDF–5.9M
15.
?F508 CFTR interactome remodeling promotes rescue of Cystic Fibrosis
Sandra Pankow, Casimir Bamberger, Diego Calzolari, Salvador Martínez-Bartolomé, Mathieu Lavallée-Adam, William E. Balch, John R. Yates, III
Nature. Author manuscript; available in PMC 2016 May 30.
Published in final edited form as: Nature. 2015 Dec 24; 528(7583): 510–516. Published online 2015 Nov 30. doi: 10.1038/nature15729
PMCID:
PMC4826614
AbstractArticlePDF–5.7M
16.
Keratin23 (KRT23) Knockdown Decreases Proliferation and Affects the DNA Damage Response of Colon Cancer Cells
Karin Birkenkamp-Demtröder, Stephan A. Hahn, Francisco Mansilla, Kasper Thorsen, Abdelouahid Maghnouj, Rikke Christensen, Bodil Øster, Torben Falck Ørntoft
PLoS One. 2013; 8(9): e73593. Published online 2013 Sep 9. doi: 10.1371/journal.pone.0073593
PMCID:
PMC3767798
AbstractArticlePDF–2.0M
17.
Identification of putative immunologic targets for colon cancer prevention based on conserved gene upregulation from pre-invasive to malignant lesions
Elizabeth K. Broussard, Rachel Kim, Jesse C. Wiley, Juan Pablo Marquez, James E. Annis, David Pritchard, Mary L. Disis
Cancer Prev Res (Phila) Author manuscript; available in PMC 2014 Jul 1.
Published in final edited form as: Cancer Prev Res (Phila). 2013 Jul; 6(7): 666–674. Published online 2013 May 16. doi: 10.1158/1940-6207.CAPR-12-0484
PMCID:
PMC3718634
AbstractArticlePDF–778K
18.
Genetic Susceptibility to Distinct Bladder Cancer Subphenotypes
Lin T. Guey, Montserrat García-Closas, Cristiane Murta-Nascimento, Josep Lloreta, Laia Palencia, Manolis Kogevinas, Nathaniel Rothman, Gemma Vellalta, Malu Calle, Gaëlle Marenne, Adonina Tardón, Alfredo Carrato, Reina García-Closas, Consol Serra, Debra T Silverman, Stephen Chanock, Francisco X. Real, Núria Malats
Eur Urol. Author manuscript; available in PMC 2011 Nov 18.
Published in final edited form as: Eur Urol. 2010 Feb; 57(2): 283–292. Published online 2009 Aug 12. doi: 10.1016/j.eururo.2009.08.001
PMCID:
PMC3220186
AbstractArticlePDF–595K
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
Keratin 23, a novel DPC4/Smad4 target gene which binds 14-3-3ε
Sven-T Liffers, Abdelouahid Maghnouj, Johanna B Munding, René Jackstadt, Ulrike Herbrand, Thomas Schulenborg, Katrin Marcus, Susanne Klein-Scory, Wolff Schmiegel, Irmgard Schwarte-Waldhoff, Helmut E Meyer, Kai Stühler, Stephan A Hahn
BMC Cancer. 2011; 11: 137. Published online 2011 Apr 14. doi: 10.1186/1471-2407-11-137
PMCID:
PMC3095566
AbstractArticlePDF–5.4M

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